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Search term: YDL029W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ARP2
SGD link S000002187
Alternative ID YDL029W
Description Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
Synonyms YDL029W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0677 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Actin-related protein Arp2/3 complex, subunit Arp2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g27000 GI:15232057
Caenorhabditis elegans (Cel) CE06111
(WBGene00000200)		 GI:17562290 P53489
Drosophila melanogaster (Dme) 7293239 GI:7293239 A8JV17
Homo sapiens (Hsa) Hs5031571 GI:5031571 P61160
Homo sapiens (Hsa) Hs18594223_1 GI:18594223
Saccharomyces cerevisiae (Sce) YDL029w
(S000002187)		 GI:6320175 P32381
Schizosaccharomyces pombe (Spo) SPAC11H11.06 GI:19115636 Q9UUJ1
Arabidopsis thaliana (Ath) At3g27000 GI:15232057
Caenorhabditis elegans (Cel) CE06111
(WBGene00000200)		 GI:17562290 P53489
Drosophila melanogaster (Dme) 7293239 GI:7293239 A8JV17
Homo sapiens (Hsa) Hs5031571 GI:5031571 P61160
Homo sapiens (Hsa) Hs18594223_1 GI:18594223
Saccharomyces cerevisiae (Sce) YDL029w
(S000002187)		 GI:6320175 P32381
Schizosaccharomyces pombe (Spo) SPAC11H11.06 GI:19115636 Q9UUJ1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002187
GO:0005885 Arp2/3 protein complex C
IDA
SceS000002187
SpoSPAC11H11.06
TAS
AthAt3g27000
GO:0030479 actin cortical patch C
IDA
SpoSPAC11H11.06
GO:0005200 structural constituent of cytoskeleton F
ISS
AthAt3g27000
GO:0005524 ATP binding F
IDA
SceS000002187
IMP
SceS000002187
GO:0016887 ATPase activity F
IMP
SceS000002187
GO:0000001 mitochondrion inheritance P
IMP
SceS000002187
IPI
SceS000002187
GO:0000147 actin cortical patch assembly P
IC
SpoSPAC11H11.06
GO:0000902 cell morphogenesis P
IMP
AthAt3g27000
GO:0002119 nematode larval development P
IMP
CelWBGene00000200
GO:0006200 ATP catabolic process P
IMP
SceS000002187
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000200
GO:0007015 actin filament organization P
IMP
AthAt3g27000
SceS000002187
GO:0007047 cellular cell wall organization P
RCA
SceS000002187
GO:0007126 meiosis P
IMP
CelWBGene00000200
GO:0009790 embryo development P
IMP
CelWBGene00000200
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000200
GO:0009825 multidimensional cell growth P
IMP
AthAt3g27000
GO:0010090 trichome morphogenesis P
IMP
AthAt3g27000
GO:0010631 epithelial cell migration P
IMP
CelWBGene00000200
GO:0016331 morphogenesis of embryonic epithelium P
IMP
CelWBGene00000200
GO:0019953 sexual reproduction P
RCA
SceS000002187
GO:0030029 actin filament-based process P
TAS
AthAt3g27000
GO:0030036 actin cytoskeleton organization P
TAS
AthAt3g27000
GO:0030100 regulation of endocytosis P
IMP
SpoSPAC11H11.06
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002187
GO:0030476 ascospore wall assembly P
IMP
SceS000002187
GO:0034314 Arp2/3 complex-mediated actin nucleation P
IDA
SpoSPAC11H11.06
IMP
CelWBGene00000200
SceS000002187
GO:0040007 growth P
IMP
CelWBGene00000200
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000200
GO:0040011 locomotion P
IMP
CelWBGene00000200
GO:0043652 engulfment of apoptotic cell P
IMP
CelWBGene00000200
GO:0048308 organelle inheritance P
RCA
SceS000002187
GO:0051654 establishment of mitochondrion
localization		 P
IMP
SceS000002187

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4181

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ACTR2 GI:53692187
Pan troglodytes (Ptr) ACTR2 GI:114577814
Canis familiaris (Cfa) ACTR2 GI:73969818
Mus musculus (Mmu) Actr2
(MGI:1913963)		 GI:22122825 P61161
Rattus norvegicus (Rno) Actr2
(RGD:1310826)		 GI:57164143
Gallus gallus (Gga) ACTR2 GI:45382569
Drosophila melanogaster (Dme) Arp14D
(FBgn0011742)		 GI:161077869
Anopheles gambiae (Aga) AgaP_AGAP000985 GI:158287121
Schizosaccharomyces pombe (Spo) SPAC22F8.01 GI:68004845
Saccharomyces cerevisiae (Sce) ARP2
(S000002187)		 GI:6320175 P32381
Kluyveromyces lactis (Kla) KLLA0C03850g GI:50304825
Eremothecium gossypii (Ego) AGOS_ADR316W GI:45188189
Magnaporthe grisea (Mgr) MGG_10690 GI:39971339
Neurospora crassa (Ncr) NCU07171.1 GI:32413955


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1913963
GO:0005739 mitochondrion C
IDA
SceS000002187
GO:0005884 actin filament C
ISS
DmeFBgn0011742
GO:0005885 Arp2/3 protein complex C
IDA
SceS000002187
ISS
DmeFBgn0011742
NAS
DmeFBgn0011742
RCA
HsaACTR2
TAS
HsaACTR2
GO:0015629 actin cytoskeleton C
NAS
DmeFBgn0011742
TAS
HsaACTR2
GO:0003674 molecular_function F
ND
MmuMGI:1913963
GO:0003779 actin binding F
ISS
DmeFBgn0011742
GO:0005200 structural constituent of cytoskeleton F
ISS
DmeFBgn0011742
GO:0005515 protein binding F
IPI
HsaACTR2
GO:0005524 ATP binding F
IDA
SceS000002187
IMP
SceS000002187
GO:0016887 ATPase activity F
IMP
SceS000002187
GO:0000001 mitochondrion inheritance P
IMP
SceS000002187
IPI
SceS000002187
GO:0006200 ATP catabolic process P
IMP
SceS000002187
GO:0006928 cellular component movement P
TAS
HsaACTR2
GO:0007010 cytoskeleton organization P
ISS
DmeFBgn0011742
GO:0007015 actin filament organization P
IMP
SceS000002187
GO:0007047 cellular cell wall organization P
RCA
SceS000002187
GO:0008064 regulation of actin polymerization or
depolymerization		 P
NAS
DmeFBgn0011742
GO:0008150 biological_process P
ND
MmuMGI:1913963
GO:0019953 sexual reproduction P
RCA
SceS000002187
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002187
GO:0030476 ascospore wall assembly P
IMP
SceS000002187
GO:0034314 Arp2/3 complex-mediated actin nucleation P
IMP
SceS000002187
GO:0048308 organelle inheritance P
RCA
SceS000002187
GO:0051654 establishment of mitochondrion
localization		 P
IMP
SceS000002187

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3281

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15697 ENSANGP00000018684
Ashbya gossypii (Ago) ago2057 ADR316W
Arabidopsis thaliana (Ath) ath15050 At3g27000.1
Caenorhabditis elegans (Cel) cel12110 K07C5.1
(CE06111;
WBGene00000200)
Candida glabrata (Cgl) cgl3589 CAGL0K01595g
Cryptococcus neoformans (Cne) cne311 162.m02873
Cryptococcus neoformans (Cne) cne312 162.m02874
Cryptococcus neoformans (Cne) cne313 162.m04104
Dictyostelium discoideum (Ddi) ddi12023 DDB0185179
Debaryomyces hansenii (Dha) dha963 DEHA0B06292g
Drosophila melanogaster (Dme) dme18199 CG9901-PA
(FBgn0011742)
Danio rerio (Dre) dre1099 ENSDARP00000049275
Takifugu rubripes (Fru) fru1502 SINFRUP00000135215
Takifugu rubripes (Fru) fru11140 SINFRUP00000136212
Gallus gallus (Gga) gga14435 ENSGALP00000014260
(ACTR2)		 P53488
Homo sapiens (Hsa) hsa17907 ENSP00000260641
(ACTR2)		 P61160
Kluyveromyces lactis (Kla) kla1367 KLLA0C03850g
Mus musculus (Mmu) mmu3308 ENSMUSP00000000137
(MGI:1913963)		 P61161
Neurospora crassa (Ncr) ncr6978 NCU07171.2
Oryza sativa (Osa) osa71995 7211.m00112
Rattus norvegicus (Rno) rno10821 ENSRNOP00000006607
(RGD:1310826)		 Q5M7U6
Rattus norvegicus (Rno) rno10822 ENSRNOP00000029024
Saccharomyces cerevisiae (Sce) sce798 YDL029W
(S000002187)
Schizosaccharomyces pombe (Spo) spo1729 SPAC11H11.06 Q9UUJ1
Yarrowia lipolytica (Yli) yli5993 YALI0F15389g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1913963
GO:0005739 mitochondrion C
IDA
SceS000002187
GO:0005884 actin filament C
ISS
DmeFBgn0011742
GO:0005885 Arp2/3 protein complex C
IDA
SceS000002187
SpoSPAC11H11.06
ISS
DmeFBgn0011742
NAS
DmeFBgn0011742
TAS
AthAt3g27000
GO:0015629 actin cytoskeleton C
NAS
DmeFBgn0011742
GO:0030479 actin cortical patch C
IDA
SpoSPAC11H11.06
GO:0003674 molecular_function F
ND
MmuMGI:1913963
GO:0003779 actin binding F
ISS
DmeFBgn0011742
GO:0005200 structural constituent of cytoskeleton F
ISS
AthAt3g27000
DmeFBgn0011742
GO:0005524 ATP binding F
IDA
SceS000002187
IMP
SceS000002187
GO:0016887 ATPase activity F
IMP
SceS000002187
GO:0000001 mitochondrion inheritance P
IMP
SceS000002187
IPI
SceS000002187
GO:0000147 actin cortical patch assembly P
IC
SpoSPAC11H11.06
GO:0000902 cell morphogenesis P
IMP
AthAt3g27000
GO:0002119 nematode larval development P
IMP
CelWBGene00000200
GO:0006200 ATP catabolic process P
IMP
SceS000002187
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000200
GO:0007010 cytoskeleton organization P
ISS
DmeFBgn0011742
GO:0007015 actin filament organization P
IMP
AthAt3g27000
SceS000002187
GO:0007047 cellular cell wall organization P
RCA
SceS000002187
GO:0007126 meiosis P
IMP
CelWBGene00000200
GO:0008064 regulation of actin polymerization or
depolymerization		 P
NAS
DmeFBgn0011742
GO:0008150 biological_process P
ND
MmuMGI:1913963
GO:0009790 embryo development P
IMP
CelWBGene00000200
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000200
GO:0009825 multidimensional cell growth P
IMP
AthAt3g27000
GO:0010090 trichome morphogenesis P
IMP
AthAt3g27000
GO:0010631 epithelial cell migration P
IMP
CelWBGene00000200
GO:0016331 morphogenesis of embryonic epithelium P
IMP
CelWBGene00000200
GO:0019953 sexual reproduction P
RCA
SceS000002187
GO:0030029 actin filament-based process P
TAS
AthAt3g27000
GO:0030036 actin cytoskeleton organization P
TAS
AthAt3g27000
GO:0030100 regulation of endocytosis P
IMP
SpoSPAC11H11.06
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002187
GO:0030476 ascospore wall assembly P
IMP
SceS000002187
GO:0034314 Arp2/3 complex-mediated actin nucleation P
IDA
SpoSPAC11H11.06
IMP
CelWBGene00000200
SceS000002187
GO:0040007 growth P
IMP
CelWBGene00000200
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000200
GO:0040011 locomotion P
IMP
CelWBGene00000200
GO:0043652 engulfment of apoptotic cell P
IMP
CelWBGene00000200
GO:0048308 organelle inheritance P
RCA
SceS000002187
GO:0051654 establishment of mitochondrion
localization		 P
IMP
SceS000002187

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC11H11.06
(Q9UUJ1)		 YDL029W
(S000002187)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002187
GO:0005885 Arp2/3 protein complex C
IDA
SceS000002187
SpoSPAC11H11.06
GO:0030479 actin cortical patch C
IDA
SpoSPAC11H11.06
GO:0005524 ATP binding F
IDA
SceS000002187
IMP
SceS000002187
GO:0016887 ATPase activity F
IMP
SceS000002187
GO:0000001 mitochondrion inheritance P
IMP
SceS000002187
IPI
SceS000002187
GO:0000147 actin cortical patch assembly P
IC
SpoSPAC11H11.06
GO:0006200 ATP catabolic process P
IMP
SceS000002187
GO:0007015 actin filament organization P
IMP
SceS000002187
GO:0007047 cellular cell wall organization P
RCA
SceS000002187
GO:0019953 sexual reproduction P
RCA
SceS000002187
GO:0030100 regulation of endocytosis P
IMP
SpoSPAC11H11.06
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002187
GO:0030476 ascospore wall assembly P
IMP
SceS000002187
GO:0034314 Arp2/3 complex-mediated actin nucleation P
IDA
SpoSPAC11H11.06
IMP
SceS000002187
GO:0048308 organelle inheritance P
RCA
SceS000002187
GO:0051654 establishment of mitochondrion
localization		 P
IMP
SceS000002187

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s.khadayate@ucl.ac.uk