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Search term: YDL052C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SLC1
SGD link S000002210
Alternative ID YDL052C
Description 1-acyl-sn-glycerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes
Synonyms YDL052C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2848 ACDHYP-

KOGs classification KOGs description
METABOLISM 1-acyl-sn-glycerol-3-phosphate acyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g30580 GI:15234773
Caenorhabditis elegans (Cel) CE06378
(WBGene00011543)		 GI:17564032 Q22267
Caenorhabditis elegans (Cel) CE11552
(WBGene00010339)		 GI:17568319 Q93841
Drosophila melanogaster (Dme) 7292807 GI:7292807 Q9VYJ4
Drosophila melanogaster (Dme) 7297421 GI:7297421
Homo sapiens (Hsa) Hs6041665
(AGPAT2)		 GI:6041665 O15120
Homo sapiens (Hsa) Hs5453718
(AGPAT1)		 GI:5453718 Q71VH6
Saccharomyces cerevisiae (Sce) YDL052c
(S000002210)		 GI:6320151 P33333
Schizosaccharomyces pombe (Spo) SPAC1851.02 GI:19115517 Q9US20


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1851.02
ISS
HsaAGPAT2
TAS
HsaAGPAT1
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC1851.02
GO:0005811 lipid particle C
IDA
SceS000002210
GO:0005829 cytosol C
EXP
HsaAGPAT1
AGPAT2
GO:0009507 chloroplast C
IDA
AthAt4g30580
GO:0009941 chloroplast envelope C
IDA
AthAt4g30580
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase
activity		 F
IDA
SceS000002210
IGI
AthAt4g30580
HsaAGPAT2
AGPAT1
ISS
SpoSPAC1851.02
NAS
HsaAGPAT2
GO:0008415 acyltransferase activity F
ISS
AthAt4g30580
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
EXP
HsaAGPAT2
AGPAT1
GO:0001819 positive regulation of cytokine
production		 P
IMP
HsaAGPAT1
AGPAT2
GO:0001961 positive regulation of cytokine-mediated signaling
pathway		 P
IC
HsaAGPAT1
AGPAT2
GO:0006644 phospholipid metabolic process P
NAS
HsaAGPAT2
TAS
HsaAGPAT1
GO:0006654 phosphatidic acid biosynthetic
process		 P
IGI
HsaAGPAT1
AGPAT2
GO:0006655 phosphatidylglycerol biosynthetic
process		 P
IMP
AthAt4g30580
GO:0008152 metabolic process P
ISS
AthAt4g30580
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt4g30580
NAS
AthAt4g30580
GO:0046474 glycerophospholipid biosynthetic
process		 P
IGI
SceS000002210
ISS
SpoSPAC1851.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4678

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AGPAT2 GI:6041665 O15120
Pan troglodytes (Ptr) AGPAT2 GI:114627621
Canis familiaris (Cfa) AGPAT2 GI:73967529
Mus musculus (Mmu) Agpat2
(MGI:1914762)		 GI:23956162 Q059U0
Rattus norvegicus (Rno) Agpat2 GI:109467913
Gallus gallus (Gga) AGPAT2 GI:118099399
Schizosaccharomyces pombe (Spo) SPAC1851.02 GI:19115517 Q9US20
Saccharomyces cerevisiae (Sce) SLC1
(S000002210)		 GI:6320151 P33333
Kluyveromyces lactis (Kla) KLLA0E01232g GI:50308007
Eremothecium gossypii (Ego) AGOS_AFR592W GI:45199110
Magnaporthe grisea (Mgr) MGG_11040 GI:39941738
Neurospora crassa (Ncr) NCU00168.1 GI:32403282


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
MmuMGI:1914762
SpoSPAC1851.02
ISS
HsaAGPAT2
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC1851.02
GO:0005811 lipid particle C
IDA
SceS000002210
GO:0005829 cytosol C
EXP
HsaAGPAT2
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase
activity		 F
IDA
MmuMGI:1914762
SceS000002210
IGI
HsaAGPAT2
ISS
SpoSPAC1851.02
NAS
HsaAGPAT2
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
EXP
HsaAGPAT2
GO:0001819 positive regulation of cytokine
production		 P
IMP
HsaAGPAT2
GO:0001961 positive regulation of cytokine-mediated signaling
pathway		 P
IC
HsaAGPAT2
GO:0006644 phospholipid metabolic process P
NAS
HsaAGPAT2
GO:0006654 phosphatidic acid biosynthetic
process		 P
IGI
HsaAGPAT2
GO:0008152 metabolic process P
IDA
MmuMGI:1914762
GO:0008654 phospholipid biosynthetic process P
NAS
MmuMGI:1914762
GO:0046474 glycerophospholipid biosynthetic
process		 P
IGI
SceS000002210
ISS
SpoSPAC1851.02

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_435

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4128 ENSANGP00000011242
Anopheles gambiae (Aga) aga11561 ENSANGP00000018852
Anopheles gambiae (Aga) aga11568 ENSANGP00000018875
Ashbya gossypii (Ago) ago3784 AFR592W
Arabidopsis thaliana (Ath) ath21114 At4g30580.1
Caenorhabditis elegans (Cel) cel14791 T06E8.1
(CE06378;
WBGene00011543)
Candida glabrata (Cgl) cgl2697 CAGL0I04070g
Cryptococcus neoformans (Cne) cne373 162.m03006
Dictyostelium discoideum (Ddi) ddi10910 DDB0183825
Debaryomyces hansenii (Dha) dha5781 DEHA0G01848g
Drosophila melanogaster (Dme) dme1476 CG17608-PA
(FBgn0026718)
Drosophila melanogaster (Dme) dme1477 CG17608-PB
(FBgn0026718)
Drosophila melanogaster (Dme) dme17610 CG3812-PA
(FBgn0030421)
Drosophila melanogaster (Dme) dme17611 CG3812-PB
(FBgn0030421)
Escherichia coli (Eco) eco2916 16130914
Takifugu rubripes (Fru) fru26675 SINFRUP00000139818
Gallus gallus (Gga) gga13682 ENSGALP00000000375
(AGPAT1)
Gallus gallus (Gga) gga8646 ENSGALP00000001452
(LOC770506)
Homo sapiens (Hsa) hsa32232 ENSP00000312239
Homo sapiens (Hsa) hsa26892 ENSP00000337463
(AGPAT1)		 Q99943
Homo sapiens (Hsa) hsa32230 ENSP00000344415
Homo sapiens (Hsa) hsa32231 ENSP00000352899
Kluyveromyces lactis (Kla) kla3003 KLLA0E01232g
Mus musculus (Mmu) mmu14275 ENSMUSP00000028286
(MGI:1914762)		 Q8K3K7
Mus musculus (Mmu) mmu11486 ENSMUSP00000048573
(MGI:1932075)		 Q8BUB3
Mus musculus (Mmu) mmu11485 ENSMUSP00000067209
Neurospora crassa (Ncr) ncr161 NCU00168.2
Oryza sativa (Osa) osa7779 2559.m00119
Oryza sativa (Osa) osa42380 5395.m00199
Plasmodium falciparum (Pfa) pfa1872 PF14_0421
Rattus norvegicus (Rno) rno17475 ENSRNOP00000000500
(RGD:1303287)		 Q6MG85
Rattus norvegicus (Rno) rno18234 ENSRNOP00000026408
(RGD:1309229)
Saccharomyces cerevisiae (Sce) sce822 YDL052C
(S000002210)
Schizosaccharomyces pombe (Spo) spo3831 SPAC1851.02 Q9US20
Yarrowia lipolytica (Yli) yli4645 YALI0E18964g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1932075
GO:0005783 endoplasmic reticulum C
IDA
MmuMGI:1914762
SpoSPAC1851.02
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC1851.02
GO:0005811 lipid particle C
IDA
SceS000002210
GO:0009507 chloroplast C
IDA
AthAt4g30580
GO:0009941 chloroplast envelope C
IDA
AthAt4g30580
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase
activity		 F
IDA
MmuMGI:1914762
MGI:1932075
SceS000002210
IGI
AthAt4g30580
ISS
DmeFBgn0030421
FBgn0026718
SpoSPAC1851.02
NAS
DmeFBgn0026718
GO:0008415 acyltransferase activity F
ISS
AthAt4g30580
GO:0006654 phosphatidic acid biosynthetic
process		 P
IDA
MmuMGI:1932075
GO:0006655 phosphatidylglycerol biosynthetic
process		 P
IMP
AthAt4g30580
GO:0008152 metabolic process P
IDA
MmuMGI:1914762
ISS
AthAt4g30580
GO:0008654 phospholipid biosynthetic process P
NAS
MmuMGI:1914762
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt4g30580
NAS
AthAt4g30580
GO:0046474 glycerophospholipid biosynthetic
process		 P
IGI
SceS000002210
ISS
SpoSPAC1851.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1851.02
(Q9US20)		 YDL052C
(S000002210)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC1851.02
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC1851.02
GO:0005811 lipid particle C
IDA
SceS000002210
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase
activity		 F
IDA
SceS000002210
ISS
SpoSPAC1851.02
GO:0046474 glycerophospholipid biosynthetic
process		 P
IGI
SceS000002210
ISS
SpoSPAC1851.02

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GO info in one table:

s.khadayate@ucl.ac.uk