Bahler Lab

Search term: YDL080C

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name THI3

SGD link S000002238

Alternative ID YDL080C

Description Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis

Synonyms YDL080C

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG1184 A---YP-

KOGs classification KOGs description

METABOLISMMETABOLISM Thiamine pyrophosphate-requiring enzyme

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005575 cellular_component C
ND
Ath At5g01320
At5g54960
Spo SPAC1F8.07c

GO:0005634 nucleus C
IDA
Sce S000004034
S000002238
S000004124
Spo SPAC3G9.11c
SPAC13A11.06
SPAC186.09

GO:0005737 cytoplasm C
IDA
Sce S000003319
S000004124
S000004034
S000002788

GO:0005829 cytosol C
IDA
Sce S000002238
S000004034
Spo SPAC3G9.11c
SPAC13A11.06
SPAC186.09

GO:0016020 membrane C
IDA
Ath At4g33070

GO:0004737 pyruvate decarboxylase activity F
IDA
Sce S000004034
S000004124
IGI
Sce S000004124
IMP
Sce S000003319
ISS
Ath At5g01330
At5g01320
At4g33070
At5g54960
Sce S000002788
Spo SPAC1F8.07c
SPAC13A11.06
SPAC186.09

GO:0016831 carboxy-lyase activity F
IMP
Sce S000002788
S000002238
ISS
Sce S000002238
S000002788

GO:0050177 phenylpyruvate decarboxylase activity F
IDA
Sce S000002788

GO:0000949 aromatic amino acid family catabolic process to
alcohol via Ehrlich pathway P
IGI
Sce S000003319
S000002788
S000004034
S000004124
ISS
Spo SPAC13A11.06

GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway P
IGI
Sce S000002238
S000002788

GO:0000951 methionine catabolic process to
3-methylthiopropanol P
IMP
Sce S000002788

GO:0001666 response to hypoxia P
IEP
Ath At5g54960

GO:0006066 alcohol metabolic process P
RCA
Sce S000004034

GO:0006067 ethanol metabolic process P
IMP
Sce S000003319

GO:0006082 organic acid metabolic process P
RCA
Sce S000004034

GO:0006090 pyruvate metabolic process P
IDA
Sce S000004124
S000004034
IGI
Sce S000004124
ISS
Spo SPAC1F8.07c
SPAC13A11.06
SPAC186.09
NAS
Spo SPAC3G9.11c

GO:0006091 generation of precursor metabolites and
energy P
NAS
Spo SPAC1F8.07c
SPAC3G9.11c
SPAC186.09

GO:0006417 regulation of translation P
RCA
Sce S000004034

GO:0006552 leucine catabolic process P
IGI
Sce S000002238
S000002788
IMP
Sce S000002788

GO:0006559 L-phenylalanine catabolic process P
IDA
Sce S000002788
IGI
Sce S000002788
S000003319
S000004034
S000004124

GO:0006569 tryptophan catabolic process P
IGI
Sce S000002788
S000004034
S000003319
S000004124

GO:0006984 ER-nucleus signaling pathway P
RCA
Sce S000003319

GO:0008152 metabolic process P
NAS
Spo SPAC1F8.07c

GO:0009063 cellular amino acid catabolic process P
ISS
Spo SPAC186.09
SPAC3G9.11c
SPAC1F8.07c

GO:0019655 glucose catabolic process to ethanol P
IDA
Sce S000004034
S000004124
IGI
Sce S000004124
ISS
Spo SPAC13A11.06

GO:0044237 cellular metabolic process P
NAS
Spo SPAC1F8.07c

GO:0044238 primary metabolic process P
NAS
Spo SPAC1F8.07c

GO:0044262 cellular carbohydrate metabolic
process P
RCA
Sce S000004034

GO:0045944 positive regulation of transcription from RNA
polymerase II promoter P
IMP
Sce S000002238

GO:0070623 regulation of thiamin biosynthetic
process P
IMP
Sce S000002238
IPI
Sce S000002238

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_59994

Species OrthoMCL
sequence Model organism
protein page UniProt link

Candida glabrata (Cgl) cgl4378 CAGL0L06842g

Saccharomyces cerevisiae (Sce) sce850 YDL080C
(S000002238)

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Sce S000002238

GO:0005829 cytosol C
IDA
Sce S000002238

GO:0016831 carboxy-lyase activity F
IMP
Sce S000002238
ISS
Sce S000002238

GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway P
IGI
Sce S000002238

GO:0006552 leucine catabolic process P
IGI
Sce S000002238

GO:0045944 positive regulation of transcription from RNA
polymerase II promoter P
IMP
Sce S000002238

GO:0070623 regulation of thiamin biosynthetic
process P
IMP
Sce S000002238
IPI
Sce S000002238

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPAC3G9.11c
(O42873) YDL080C
(S000002238)

SPAC13A11.06
(Q09737) YDL080C
(S000002238)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Sce S000002238
Spo SPAC3G9.11c
SPAC13A11.06

GO:0005829 cytosol C
IDA
Sce S000002238
Spo SPAC3G9.11c
SPAC13A11.06

GO:0004737 pyruvate decarboxylase activity F
ISS
Spo SPAC13A11.06

GO:0016831 carboxy-lyase activity F
IMP
Sce S000002238
ISS
Sce S000002238

GO:0000949 aromatic amino acid family catabolic process to
alcohol via Ehrlich pathway P
ISS
Spo SPAC13A11.06

GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway P
IGI
Sce S000002238

GO:0006090 pyruvate metabolic process P
ISS
Spo SPAC13A11.06
NAS
Spo SPAC3G9.11c

GO:0006091 generation of precursor metabolites and
energy P
NAS
Spo SPAC3G9.11c

GO:0006552 leucine catabolic process P
IGI
Sce S000002238

GO:0009063 cellular amino acid catabolic process P
ISS
Spo SPAC3G9.11c

GO:0019655 glucose catabolic process to ethanol P
ISS
Spo SPAC13A11.06

GO:0045944 positive regulation of transcription from RNA
polymerase II promoter P
IMP
Sce S000002238

GO:0070623 regulation of thiamin biosynthetic
process P
IMP
Sce S000002238
IPI
Sce S000002238

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YOGY Home

YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG1184	A---YP-

KOGs classification	KOGs description
METABOLISMMETABOLISM	Thiamine pyrophosphate-requiring enzyme

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At4g33070	GI:15234062
Arabidopsis thaliana (Ath)	At5g01320	GI:15240950
Arabidopsis thaliana (Ath)	At5g01330	GI:15240952
Arabidopsis thaliana (Ath)	At5g54960	GI:15240423
Saccharomyces cerevisiae (Sce)	YDL080c (S000002238)	GI:6320123	Q07471
Saccharomyces cerevisiae (Sce)	YDR380w (S000002788)	GI:6320588	Q06408
Saccharomyces cerevisiae (Sce)	YGR087c (S000003319)	GI:6321524	P26263
Saccharomyces cerevisiae (Sce)	YLR044c (S000004034)	GI:6323073	P06169
Saccharomyces cerevisiae (Sce)	YLR134w (S000004124)	GI:6323163	P16467
Schizosaccharomyces pombe (Spo)	SPAC13A11.06	GI:19113906	Q09737
Schizosaccharomyces pombe (Spo)	SPAC186.09	GI:19115939	Q9P7P6
Schizosaccharomyces pombe (Spo)	SPAC1F8.07c	GI:19113708	Q92345
Schizosaccharomyces pombe (Spo)	SPAC3G9.11c	GI:19114995	O42873
Arabidopsis thaliana (Ath)	At4g33070	GI:15234062
Arabidopsis thaliana (Ath)	At5g01320	GI:15240950
Arabidopsis thaliana (Ath)	At5g01330	GI:15240952
Arabidopsis thaliana (Ath)	At5g54960	GI:15240423
Saccharomyces cerevisiae (Sce)	YDL080c (S000002238)	GI:6320123	Q07471
Saccharomyces cerevisiae (Sce)	YDR380w (S000002788)	GI:6320588	Q06408
Saccharomyces cerevisiae (Sce)	YGR087c (S000003319)	GI:6321524	P26263
Saccharomyces cerevisiae (Sce)	YLR044c (S000004034)	GI:6323073	P06169
Saccharomyces cerevisiae (Sce)	YLR134w (S000004124)	GI:6323163	P16467
Schizosaccharomyces pombe (Spo)	SPAC13A11.06	GI:19113906	Q09737
Schizosaccharomyces pombe (Spo)	SPAC186.09	GI:19115939	Q9P7P6
Schizosaccharomyces pombe (Spo)	SPAC1F8.07c	GI:19113708	Q92345
Schizosaccharomyces pombe (Spo)	SPAC3G9.11c	GI:19114995	O42873

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Candida glabrata (Cgl)	cgl4378	CAGL0L06842g
Saccharomyces cerevisiae (Sce)	sce850	YDL080C (S000002238)

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC3G9.11c (O42873)	YDL080C (S000002238)
SPAC13A11.06 (Q09737)	YDL080C (S000002238)