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Search term: YDL090C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAM1
SGD link S000002248
Alternative ID YDL090C
Description Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit
Synonyms YDL090C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0365 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Beta subunit of farnesyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g40280 GI:15242635
Caenorhabditis elegans (Cel) CE09598
(WBGene00006465)		 GI:17560090 Q19752
Drosophila melanogaster (Dme) 7300143 GI:7300143
Homo sapiens (Hsa) Hs10835059
(FNTB)		 GI:10835059 P49356
Saccharomyces cerevisiae (Sce) YDL090c
(S000002248)		 GI:6320113 P22007
Schizosaccharomyces pombe (Spo) SPAC17G6.04c GI:19115163 O13782
Arabidopsis thaliana (Ath) At5g40280 GI:15242635
Caenorhabditis elegans (Cel) CE09598
(WBGene00006465)		 GI:17560090 Q19752
Drosophila melanogaster (Dme) 7300143 GI:7300143
Homo sapiens (Hsa) Hs10835059
(FNTB)		 GI:10835059 P49356
Saccharomyces cerevisiae (Sce) YDL090c
(S000002248)		 GI:6320113 P22007
Schizosaccharomyces pombe (Spo) SPAC17G6.04c GI:19115163 O13782
Arabidopsis thaliana (Ath) At5g40280 GI:15242635
Caenorhabditis elegans (Cel) CE09598
(WBGene00006465)		 GI:17560090 Q19752
Drosophila melanogaster (Dme) 7300143 GI:7300143
Homo sapiens (Hsa) Hs10835059
(FNTB)		 GI:10835059 P49356
Saccharomyces cerevisiae (Sce) YDL090c
(S000002248)		 GI:6320113 P22007
Schizosaccharomyces pombe (Spo) SPAC17G6.04c GI:19115163 O13782


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17G6.04c
GO:0005829 cytosol C
IDA
SpoSPAC17G6.04c
GO:0005875 microtubule associated complex C
IDA
HsaFNTB
GO:0005965 protein farnesyltransferase complex C
IDA
SceS000002248
IMP
AthAt5g40280
GO:0004311 farnesyltranstransferase activity F
ISS
AthAt5g40280
GO:0004660 protein farnesyltransferase activity F
IDA
HsaFNTB
SceS000002248
SpoSPAC17G6.04c
IMP
AthAt5g40280
GO:0005515 protein binding F
IPI
HsaFNTB
GO:0008270 zinc ion binding F
NAS
SpoSPAC17G6.04c
GO:0006995 cellular response to nitrogen starvation P
IGI
SpoSPAC17G6.04c
GO:0009414 response to water deprivation P
IMP
AthAt5g40280
GO:0009737 response to abscisic acid stimulus P
IMP
AthAt5g40280
GO:0009788 negative regulation of abscisic acid mediated
signaling pathway		 P
IMP
AthAt5g40280
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006465
GO:0009934 regulation of meristem structural
organization		 P
IMP
AthAt5g40280
GO:0010958 regulation of amino acid import P
IGI
SpoSPAC17G6.04c
GO:0018342 protein prenylation P
IMP
AthAt5g40280
GO:0018347 protein amino acid farnesylation P
IDA
HsaFNTB
SceS000002248
SpoSPAC17G6.04c
IGI
SpoSPAC17G6.04c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1535

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FNTB GI:10835059 P49356
Pan troglodytes (Ptr) FNTB GI:114653514
Canis familiaris (Cfa) FNTB GI:73964211
Mus musculus (Mmu) Fntb
(MGI:1861305)		 GI:22122343 Q8K2I1
Rattus norvegicus (Rno) Fntb
(RGD:620119)		 GI:25282399
Drosophila melanogaster (Dme) CG17565
(FBgn0038424)		 GI:21355687
Anopheles gambiae (Aga) AgaP_AGAP001729 GI:158301703
Caenorhabditis elegans (Cel) tag-114
(CE09598;
WBGene00006465)		 GI:17560090 Q19752
Schizosaccharomyces pombe (Spo) cpp1
(SPAC17G6.04c)		 GI:19115163 O13782
Saccharomyces cerevisiae (Sce) RAM1
(S000002248)		 GI:6320113 P22007
Kluyveromyces lactis (Kla) KLLA0F07161g GI:50310765
Eremothecium gossypii (Ego) AGOS_ADR275W GI:45188148
Magnaporthe grisea (Mgr) MGG_01287 GI:145613884
Neurospora crassa (Ncr) NCU05999.1 GI:32410747
Arabidopsis thaliana (Ath) ERA1 GI:15242635
Oryza sativa (Osa) Os01g0737800 GI:115439807
Plasmodium falciparum (Pfa) PF11_0483 GI:124804919


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17G6.04c
GO:0005829 cytosol C
IDA
SpoSPAC17G6.04c
GO:0005875 microtubule associated complex C
IDA
HsaFNTB
GO:0005965 protein farnesyltransferase complex C
IDA
SceS000002248
IMP
AthERA1
ISS
PfaPF11_0483
GO:0005968 Rab-protein geranylgeranyltransferase
complex		 C
ISS
DmeFBgn0038424
GO:0043234 protein complex C
ISO
MmuMGI:1861305
GO:0004311 farnesyltranstransferase activity F
IMP
MmuMGI:1861305
ISS
AthERA1
GO:0004660 protein farnesyltransferase activity F
IDA
HsaFNTB
SceS000002248
SpoSPAC17G6.04c
IMP
AthERA1
ISO
MmuMGI:1861305
ISS
PfaPF11_0483
GO:0004663 Rab geranylgeranyltransferase activity F
ISS
DmeFBgn0038424
GO:0005515 protein binding F
IPI
HsaFNTB
GO:0008144 drug binding F
ISO
MmuMGI:1861305
GO:0008270 zinc ion binding F
ISO
MmuMGI:1861305
ISS
PfaPF11_0483
NAS
SpoSPAC17G6.04c
GO:0019840 isoprenoid binding F
ISO
MmuMGI:1861305
GO:0042277 peptide binding F
ISO
MmuMGI:1861305
GO:0006995 cellular response to nitrogen starvation P
IGI
SpoSPAC17G6.04c
GO:0008152 metabolic process P
IMP
MmuMGI:1861305
GO:0008284 positive regulation of cell proliferation P
IMP
MmuMGI:1861305
ISO
MmuMGI:1861305
GO:0008285 negative regulation of cell proliferation P
IMP
MmuMGI:1861305
GO:0009414 response to water deprivation P
IMP
AthERA1
GO:0009737 response to abscisic acid stimulus P
IMP
AthERA1
GO:0009788 negative regulation of abscisic acid mediated
signaling pathway		 P
IMP
AthERA1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006465
GO:0009934 regulation of meristem structural
organization		 P
IMP
AthERA1
GO:0010035 response to inorganic substance P
ISO
MmuMGI:1861305
GO:0010958 regulation of amino acid import P
IGI
SpoSPAC17G6.04c
GO:0014070 response to organic cyclic substance P
ISO
MmuMGI:1861305
GO:0018342 protein prenylation P
IMP
AthERA1
GO:0018347 protein amino acid farnesylation P
IDA
HsaFNTB
SceS000002248
SpoSPAC17G6.04c
IGI
SpoSPAC17G6.04c
ISS
PfaPF11_0483
GO:0034097 response to cytokine stimulus P
ISO
MmuMGI:1861305
GO:0042060 wound healing P
IMP
MmuMGI:1861305
GO:0045787 positive regulation of cell cycle P
ISO
MmuMGI:1861305
GO:0048146 positive regulation of fibroblast
proliferation		 P
IMP
MmuMGI:1861305
GO:0051773 positive regulation of nitric-oxide synthase 2
biosynthetic process		 P
ISO
MmuMGI:1861305

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2395

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3842 ENSANGP00000008499
Ashbya gossypii (Ago) ago2016 ADR275W
Arabidopsis thaliana (Ath) ath25800 At5g40280.1
Caenorhabditis elegans (Cel) cel7095 F23B12.6
(CE09598;
WBGene00006465)
Candida glabrata (Cgl) cgl4390 CAGL0L07106g
Cryptococcus neoformans (Cne) cne1179 180.m00108
Dictyostelium discoideum (Ddi) ddi1876 DDB0216701
Debaryomyces hansenii (Dha) dha6504 DEHA0G18007g
Drosophila melanogaster (Dme) dme12924 CG17565-PA
(FBgn0038424)
Danio rerio (Dre) dre17363 ENSDARP00000034563
(fntb)		 Q6IQG3
Danio rerio (Dre) dre17364 ENSDARP00000036073
Takifugu rubripes (Fru) fru1708 SINFRUP00000132281
Homo sapiens (Hsa) hsa9683 ENSP00000246166
(FNTB)		 P49356
Kluyveromyces lactis (Kla) kla4405 KLLA0F07161g
Mus musculus (Mmu) mmu5890 ENSMUSP00000035498
(MGI:1861305)		 Q8K2I1
Neurospora crassa (Ncr) ncr5831 NCU05999.2
Oryza sativa (Osa) osa42235 5147.m00126
Oryza sativa (Osa) osa42244 5147.m00167
Plasmodium falciparum (Pfa) pfa930 PF11_0483
Rattus norvegicus (Rno) rno25305 ENSRNOP00000010588
(RGD:620119)		 Q02293
Saccharomyces cerevisiae (Sce) sce862 YDL090C
(S000002248)
Schizosaccharomyces pombe (Spo) spo2162 SPAC17G6.04c O13782
Yarrowia lipolytica (Yli) yli3318 YALI0D14762g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17G6.04c
GO:0005829 cytosol C
IDA
SpoSPAC17G6.04c
GO:0005965 protein farnesyltransferase complex C
IDA
SceS000002248
IMP
AthAt5g40280
ISS
PfaPF11_0483
GO:0005968 Rab-protein geranylgeranyltransferase
complex		 C
ISS
DmeFBgn0038424
GO:0043234 protein complex C
ISO
MmuMGI:1861305
GO:0004311 farnesyltranstransferase activity F
IMP
MmuMGI:1861305
ISS
AthAt5g40280
GO:0004660 protein farnesyltransferase activity F
IDA
SceS000002248
SpoSPAC17G6.04c
IMP
AthAt5g40280
ISO
MmuMGI:1861305
ISS
PfaPF11_0483
GO:0004663 Rab geranylgeranyltransferase activity F
ISS
DmeFBgn0038424
GO:0008144 drug binding F
ISO
MmuMGI:1861305
GO:0008270 zinc ion binding F
ISO
MmuMGI:1861305
ISS
PfaPF11_0483
NAS
SpoSPAC17G6.04c
GO:0019840 isoprenoid binding F
ISO
MmuMGI:1861305
GO:0042277 peptide binding F
ISO
MmuMGI:1861305
GO:0006995 cellular response to nitrogen starvation P
IGI
SpoSPAC17G6.04c
GO:0008152 metabolic process P
IMP
MmuMGI:1861305
GO:0008284 positive regulation of cell proliferation P
IMP
MmuMGI:1861305
ISO
MmuMGI:1861305
GO:0008285 negative regulation of cell proliferation P
IMP
MmuMGI:1861305
GO:0009414 response to water deprivation P
IMP
AthAt5g40280
GO:0009737 response to abscisic acid stimulus P
IMP
AthAt5g40280
GO:0009788 negative regulation of abscisic acid mediated
signaling pathway		 P
IMP
AthAt5g40280
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006465
GO:0009934 regulation of meristem structural
organization		 P
IMP
AthAt5g40280
GO:0010035 response to inorganic substance P
ISO
MmuMGI:1861305
GO:0010958 regulation of amino acid import P
IGI
SpoSPAC17G6.04c
GO:0014070 response to organic cyclic substance P
ISO
MmuMGI:1861305
GO:0018342 protein prenylation P
IMP
AthAt5g40280
GO:0018347 protein amino acid farnesylation P
IDA
SceS000002248
SpoSPAC17G6.04c
IGI
SpoSPAC17G6.04c
ISS
PfaPF11_0483
GO:0034097 response to cytokine stimulus P
ISO
MmuMGI:1861305
GO:0042060 wound healing P
IMP
MmuMGI:1861305
GO:0045787 positive regulation of cell cycle P
ISO
MmuMGI:1861305
GO:0048146 positive regulation of fibroblast
proliferation		 P
IMP
MmuMGI:1861305
GO:0051773 positive regulation of nitric-oxide synthase 2
biosynthetic process		 P
ISO
MmuMGI:1861305

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC17G6.04c
(O13782)		 YDL090C
(S000002248)