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Search term: YDL108W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name KIN28
SGD link S000002266
Alternative ID YDL108W
Description Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters
Synonyms YDL108W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0659 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18040 GI:15220917
Arabidopsis thaliana (Ath) At1g66750 GI:15219730
Arabidopsis thaliana (Ath) At1g73690 GI:15219522
Caenorhabditis elegans (Cel) CE11556 GI:17540938
Caenorhabditis elegans (Cel) CE26988 GI:17509903
Drosophila melanogaster (Dme) 7290565
(FBgn0015617)
GI:17530793
Drosophila melanogaster (Dme) 7300773 GI:7300773 Q9VD82
Homo sapiens (Hsa) Hs4502743
(CDK7)
GI:4502743 P50613
Homo sapiens (Hsa) Hs7106269 GI:7106269
Saccharomyces cerevisiae (Sce) YDL108w
(S000002266)
GI:6320095 P06242
Schizosaccharomyces pombe (Spo) SPBC19F8.07 GI:19113141 Q12126
Encephalitozoon cuniculi (Ecu) ECU02g1450 GI:19074064 Q8SW92
Arabidopsis thaliana (Ath) At1g18040 GI:15220917
Arabidopsis thaliana (Ath) At1g66750 GI:15219730
Arabidopsis thaliana (Ath) At1g73690 GI:15219522
Caenorhabditis elegans (Cel) CE11556 GI:17540938
Caenorhabditis elegans (Cel) CE26988 GI:17509903
Drosophila melanogaster (Dme) 7290565
(FBgn0015617)
GI:17530793
Drosophila melanogaster (Dme) 7300773 GI:7300773 Q9VD82
Homo sapiens (Hsa) Hs4502743
(CDK7)
GI:4502743 P50613
Homo sapiens (Hsa) Hs7106269 GI:7106269
Saccharomyces cerevisiae (Sce) YDL108w
(S000002266)
GI:6320095 P06242
Schizosaccharomyces pombe (Spo) SPBC19F8.07 GI:19113141 Q12126
Encephalitozoon cuniculi (Ecu) ECU02g1450 GI:19074064 Q8SW92


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
AthAt1g73690
At1g18040
At1g66750
HsaCDK7
SpoSPBC19F8.07
GO:0005654 nucleoplasm C
EXP
HsaCDK7
GO:0005675 holo TFIIH complex C
IDA
HsaCDK7
SceS000002266
ISS
DmeFBgn0015617
SpoSPBC19F8.07
GO:0005737 cytoplasm C
IDA
AthAt1g66750
HsaCDK7
SpoSPBC19F8.07
GO:0005739 mitochondrion C
IDA
HsaCDK7
GO:0005829 cytosol C
IDA
SpoSPBC19F8.07
GO:0070985 TFIIK complex C
IDA
SceS000002266
GO:0003713 transcription coactivator activity F
NAS
HsaCDK7
GO:0004672 protein kinase activity F
IDA
HsaCDK7
TAS
AthAt1g18040
GO:0004674 protein serine/threonine kinase
activity
F
IDA
DmeFBgn0015617
NAS
DmeFBgn0015617
TAS
AthAt1g66750
GO:0004693 cyclin-dependent protein kinase
activity
F
ISS
DmeFBgn0015617
NAS
SpoSPBC19F8.07
TAS
HsaCDK7
GO:0005515 protein binding F
IPI
AthAt1g66750
GO:0008022 protein C-terminus binding F
IPI
HsaCDK7
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaCDK7
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity
F
IDA
HsaCDK7
SceS000002266
SpoSPBC19F8.07
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
SceS000002266
ISS
DmeFBgn0015617
SpoSPBC19F8.07
GO:0016301 kinase activity F
ISS
AthAt1g66750
At1g73690
At1g18040
GO:0019912 cyclin-dependent protein kinase activating kinase
activity
F
IGI
SpoSPBC19F8.07
GO:0050681 androgen receptor binding F
NAS
HsaCDK7
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
IDA
DmeFBgn0015617
TAS
AthAt1g66750
HsaCDK7
GO:0000718 nucleotide-excision repair, DNA damage
removal
P
EXP
HsaCDK7
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
HsaCDK7
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
EXP
HsaCDK7
ISS
DmeFBgn0015617
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
EXP
HsaCDK7
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPBC19F8.07
IDA
DmeFBgn0015617
NAS
DmeFBgn0015617
GO:0007067 mitosis P
IMP
DmeFBgn0015617
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC19F8.07
GO:0008283 cell proliferation P
TAS
HsaCDK7
GO:0030154 cell differentiation P
TAS
AthAt1g73690
GO:0030521 androgen receptor signaling pathway P
NAS
HsaCDK7
GO:0032568 general transcription from RNA polymerase II
promoter
P
IDA
SceS000002266
IMP
SceS000002266
GO:0042327 positive regulation of phosphorylation P
IGI
SpoSPBC19F8.07
GO:0045893 positive regulation of transcription,
DNA-dependent
P
NAS
HsaCDK7
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IDA
HsaCDK7
ISS
SpoSPBC19F8.07
GO:0051726 regulation of cell cycle P
TAS
AthAt1g73690
At1g18040
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain
P
IDA
SceS000002266
IMP
SpoSPBC19F8.07
GO:0070817 P-TEFb-cap methyltransferase complex
localization
P
IMP
SpoSPBC19F8.07
GO:0090039 regulation of gene-specific transcription
elongation from RNA polymerase II
promoter
P
IMP
SpoSPBC19F8.07

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1363

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CDK7 GI:4502743 P50613
Pan troglodytes (Ptr) CDK7 GI:114599911
Canis familiaris (Cfa) CDK7 GI:73949665
Mus musculus (Mmu) Cdk7
(MGI:102956)
GI:33859522 Q03147
Rattus norvegicus (Rno) Cdk7
(RGD:621124)
GI:34853514
Drosophila melanogaster (Dme) Cdk7
(FBgn0015617)
GI:17530793
Anopheles gambiae (Aga) AgaP_AGAP002646 GI:158290711
Caenorhabditis elegans (Cel) cdk-7
(CE30320;
WBGene00000408)
GI:25145738
Schizosaccharomyces pombe (Spo) crk1 GI:19113141
Saccharomyces cerevisiae (Sce) KIN28
(S000002266)
GI:6320095 P06242
Kluyveromyces lactis (Kla) KLLA0E14828g GI:50309219
Eremothecium gossypii (Ego) AGOS_ADL283W GI:45187590
Magnaporthe grisea (Mgr) MGG_13401 GI:145609287
Neurospora crassa (Ncr) NCU03659.1 GI:32404696
Arabidopsis thaliana (Ath) CAK4 GI:15219730


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
CelWBGene00000408
GO:0005624 membrane fraction C
ISO
MmuMGI:102956
GO:0005634 nucleus C
IDA
AthCAK4
HsaCDK7
MmuMGI:102956
ISO
MmuMGI:102956
GO:0005654 nucleoplasm C
EXP
HsaCDK7
GO:0005675 holo TFIIH complex C
IDA
HsaCDK7
SceS000002266
ISS
DmeFBgn0015617
GO:0005737 cytoplasm C
IDA
AthCAK4
HsaCDK7
GO:0005739 mitochondrion C
IDA
HsaCDK7
GO:0005829 cytosol C
ISO
MmuMGI:102956
GO:0005856 cytoskeleton C
ISO
MmuMGI:102956
GO:0070985 TFIIK complex C
IDA
SceS000002266
GO:0003713 transcription coactivator activity F
NAS
HsaCDK7
GO:0004672 protein kinase activity F
IDA
HsaCDK7
MmuMGI:102956
GO:0004674 protein serine/threonine kinase
activity
F
IDA
DmeFBgn0015617
NAS
DmeFBgn0015617
TAS
AthCAK4
GO:0004693 cyclin-dependent protein kinase
activity
F
ISO
MmuMGI:102956
ISS
CelWBGene00000408
DmeFBgn0015617
MmuMGI:102956
TAS
HsaCDK7
GO:0005515 protein binding F
IPI
AthCAK4
MmuMGI:102956
GO:0008022 protein C-terminus binding F
IPI
HsaCDK7
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaCDK7
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity
F
IDA
HsaCDK7
SceS000002266
GO:0016251 general RNA polymerase II transcription factor
activity
F
IDA
SceS000002266
ISS
DmeFBgn0015617
GO:0016301 kinase activity F
IDA
MmuMGI:102956
ISS
AthCAK4
GO:0032403 protein complex binding F
ISO
MmuMGI:102956
GO:0050681 androgen receptor binding F
NAS
HsaCDK7
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
IDA
DmeFBgn0015617
TAS
AthCAK4
HsaCDK7
GO:0000718 nucleotide-excision repair, DNA damage
removal
P
EXP
HsaCDK7
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
HsaCDK7
GO:0006367 transcription initiation from RNA polymerase II
promoter
P
EXP
HsaCDK7
ISS
DmeFBgn0015617
GO:0006368 RNA elongation from RNA polymerase II
promoter
P
EXP
HsaCDK7
GO:0006468 protein amino acid phosphorylation P
IDA
DmeFBgn0015617
ISO
MmuMGI:102956
ISS
CelWBGene00000408
NAS
DmeFBgn0015617
GO:0007049 cell cycle P
ISS
MmuMGI:102956
GO:0007067 mitosis P
IMP
DmeFBgn0015617
GO:0008283 cell proliferation P
TAS
HsaCDK7
GO:0009299 mRNA transcription P
IDA
CelWBGene00000408
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00000408
GO:0016310 phosphorylation P
IDA
MmuMGI:102956
ISS
MmuMGI:102956
GO:0030521 androgen receptor signaling pathway P
NAS
HsaCDK7
GO:0032568 general transcription from RNA polymerase II
promoter
P
IDA
SceS000002266
IMP
SceS000002266
GO:0045448 mitotic cell cycle, embryonic P
IMP
CelWBGene00000408
GO:0045893 positive regulation of transcription,
DNA-dependent
P
NAS
HsaCDK7
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IDA
HsaCDK7
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain
P
IDA
SceS000002266

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2769

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4861 ENSANGP00000002848
Ashbya gossypii (Ago) ago1458 ADL283W
Arabidopsis thaliana (Ath) ath1935 At1g18040.1
Arabidopsis thaliana (Ath) ath5905 At1g66750.1
Arabidopsis thaliana (Ath) ath6671 At1g73690.1
Caenorhabditis elegans (Cel) cel18578 Y39G10AL.3
(CE30320;
WBGene00000408)
Candida glabrata (Cgl) cgl2513 CAGL0H10318g
Cryptococcus neoformans (Cne) cne2876 183.m01889
Cryptococcus neoformans (Cne) cne2877 183.m01890
Dictyostelium discoideum (Ddi) ddi12974 DDB0191429
Debaryomyces hansenii (Dha) dha6705 DEHA0G22528g
Drosophila melanogaster (Dme) dme16552 CG3319-PA
(FBgn0015617)
Danio rerio (Dre) dre31290 ENSDARP00000007199
Danio rerio (Dre) dre19827 ENSDARP00000042043
Encephalitozoon cuniculi (Ecu) ecu143 19074064
Takifugu rubripes (Fru) fru14601 SINFRUP00000151161
Gallus gallus (Gga) gga27600 ENSGALP00000023830
(CDK7)
Homo sapiens (Hsa) hsa25323 ENSP00000256443
(CDK7)
P50613
Kluyveromyces lactis (Kla) kla3615 KLLA0E14828g
Mus musculus (Mmu) mmu31484 ENSMUSP00000073298
Mus musculus (Mmu) mmu7473 ENSMUSP00000078328
Neurospora crassa (Ncr) ncr3550 NCU03659.2
Oryza sativa (Osa) osa26090 3916.m00171
Oryza sativa (Osa) osa26758 3954.m00117
Rattus norvegicus (Rno) rno15438 ENSRNOP00000025026
(RGD:621124)
P51952
Saccharomyces cerevisiae (Sce) sce880 YDL108W
(S000002266)
Schizosaccharomyces pombe (Spo) spo1333 SPBC19F8.07 Q12126
Yarrowia lipolytica (Yli) yli2884 YALI0D04334g