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Search term: YDL125C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HNT1
SGD link S000002283
Alternative ID YDL125C
Description Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint
Synonyms YDL125C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3275 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Zinc-binding protein of the histidine triad (HIT) family

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g31160 GI:15221629
Arabidopsis thaliana (Ath) At3g56490 GI:11260559
Caenorhabditis elegans (Cel) CE05678
(WBGene00009002)
GI:17506713 P53795
Drosophila melanogaster (Dme) 7295909 GI:7295909
Homo sapiens (Hsa) Hs4885413
(HINT1)
GI:4885413 P49773
Homo sapiens (Hsa) Hs18565973 GI:18565973
Homo sapiens (Hsa) Hs14211923
(HINT2)
GI:14211923 Q8WYJ5
Saccharomyces cerevisiae (Sce) YDL125c
(S000002283)
GI:6320078 Q04344
Schizosaccharomyces pombe (Spo) SPCC1442.14c GI:19075828 O94586
Encephalitozoon cuniculi (Ecu) ECU08g0390 GI:19173365 Q8SRE4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002283
SpoSPCC1442.14c
ISS
SpoSPCC1442.14c
GO:0005737 cytoplasm C
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0005739 mitochondrion C
ISS
HsaHINT2
GO:0005777 peroxisome C
IDA
AthAt3g56490
GO:0005829 cytosol C
IDA
SpoSPCC1442.14c
GO:0005856 cytoskeleton C
TAS
HsaHINT1
GO:0005886 plasma membrane C
IDA
AthAt3g56490
GO:0009507 chloroplast C
IDA
AthAt1g31160
GO:0000166 nucleotide binding F
ISS
SceS000002283
SpoSPCC1442.14c
GO:0005080 protein kinase C binding F
ISS
AthAt3g56490
At1g31160
TAS
HsaHINT1
GO:0008270 zinc ion binding F
ISS
AthAt3g56490
At1g31160
GO:0016787 hydrolase activity F
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0043530 adenosine 5'-monophosphoramidase
activity
F
NAS
SpoSPCC1442.14c
GO:0047627 adenylylsulfatase activity F
IDA
AthAt3g56490
GO:0006414 translational elongation P
RCA
SceS000002283
GO:0006790 sulfur metabolic process P
IDA
AthAt3g56490
GO:0007165 signal transduction P
TAS
HsaHINT1
GO:0008150 biological_process P
ND
AthAt1g31160
GO:0009117 nucleotide metabolic process P
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0009150 purine ribonucleotide metabolic
process
P
IDA
AthAt3g56490

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38585

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPCC1442.14c GI:19075828 O94586
Saccharomyces cerevisiae (Sce) HNT1
(S000002283)
GI:6320078 Q04344
Kluyveromyces lactis (Kla) KLLA0F05731g GI:50310639
Eremothecium gossypii (Ego) AGOS_AFR157W GI:45198675
Magnaporthe grisea (Mgr) MGG_00872 GI:145610837
Neurospora crassa (Ncr) NCU06876.1 GI:32413365


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002283
SpoSPCC1442.14c
ISS
SpoSPCC1442.14c
GO:0005737 cytoplasm C
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0005829 cytosol C
IDA
SpoSPCC1442.14c
GO:0000166 nucleotide binding F
ISS
SceS000002283
SpoSPCC1442.14c
GO:0016787 hydrolase activity F
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0043530 adenosine 5'-monophosphoramidase
activity
F
NAS
SpoSPCC1442.14c
GO:0006414 translational elongation P
RCA
SceS000002283
GO:0009117 nucleotide metabolic process P
IDA
SceS000002283
ISS
SpoSPCC1442.14c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_461

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga1786 ENSANGP00000012999
Anopheles gambiae (Aga) aga3133 ENSANGP00000029056
Ashbya gossypii (Ago) ago3349 AFR157W
Arabidopsis thaliana (Ath) ath3255 At1g31160.1
Arabidopsis thaliana (Ath) ath17040 At3g56490.1
Arabidopsis thaliana (Ath) ath26755 At5g48545.1
Caenorhabditis elegans (Cel) cel6895 F21C3.3
(CE05678;
WBGene00009002)
Candida glabrata (Cgl) cgl3402 CAGL0J09372g
Cryptococcus neoformans (Cne) cne5174 179.m00020
Dictyostelium discoideum (Ddi) ddi12872 DDB0216234
Dictyostelium discoideum (Ddi) ddi7443 DDB0219436
Debaryomyces hansenii (Dha) dha6413 DEHA0G16016g
Drosophila melanogaster (Dme) dme454 CG2862-PA
(FBgn0031459)
Drosophila melanogaster (Dme) dme455 CG2862-PB
(FBgn0031459)
Escherichia coli (Eco) eco1067 49176077
Encephalitozoon cuniculi (Ecu) ecu196 19173365
Takifugu rubripes (Fru) fru10874 SINFRUP00000155788
Takifugu rubripes (Fru) fru3187 SINFRUP00000156464
Gallus gallus (Gga) gga28416 ENSGALP00000000583
(HINT1)
Q9I882
Homo sapiens (Hsa) hsa31245 ENSP00000259667
(HINT2)
Q9BX68
Homo sapiens (Hsa) hsa25673 ENSP00000304229
(HINT1)
P49773
Kluyveromyces lactis (Kla) kla4340 KLLA0F05731g
Mus musculus (Mmu) mmu3670 ENSMUSP00000020504
(MGI:1321133)
P70349
Mus musculus (Mmu) mmu18043 ENSMUSP00000030192
(MGI:1916167)
Q9D0S9
Neurospora crassa (Ncr) ncr4378 NCU04509.2
Neurospora crassa (Ncr) ncr6689 NCU06876.2
Oryza sativa (Osa) osa2752 1956.m00177
Oryza sativa (Osa) osa2856 1958.m00130
Oryza sativa (Osa) osa67093 6945.m00102
Plasmodium falciparum (Pfa) pfa2153 PF08_0059
Rattus norvegicus (Rno) rno4996 ENSRNOP00000000772
(RGD:620960)
P62959
Rattus norvegicus (Rno) rno21389 ENSRNOP00000007437
Rattus norvegicus (Rno) rno23040 ENSRNOP00000021387
(RGD:1308910)
Saccharomyces cerevisiae (Sce) sce898 YDL125C
(S000002283)
Schizosaccharomyces pombe (Spo) spo3255 SPCC1442.14c O94586
Yarrowia lipolytica (Yli) yli1372 YALI0B15202g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
MmuMGI:1321133
SceS000002283
SpoSPCC1442.14c
ISS
SpoSPCC1442.14c
GO:0005737 cytoplasm C
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0005739 mitochondrion C
IDA
MmuMGI:1916167
GO:0005777 peroxisome C
IDA
AthAt3g56490
At5g48545
GO:0005829 cytosol C
IDA
SpoSPCC1442.14c
GO:0005886 plasma membrane C
IDA
AthAt3g56490
GO:0009507 chloroplast C
IDA
AthAt1g31160
GO:0000166 nucleotide binding F
ISS
SceS000002283
SpoSPCC1442.14c
GO:0003674 molecular_function F
ND
MmuMGI:1916167
GO:0005080 protein kinase C binding F
ISS
AthAt3g56490
At1g31160
GO:0008252 nucleotidase activity F
ISS
DmeFBgn0031459
GO:0008270 zinc ion binding F
ISS
AthAt3g56490
At1g31160
GO:0008426 protein kinase C inhibitor activity F
ISS
PfaPF08_0059
GO:0016787 hydrolase activity F
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0043530 adenosine 5'-monophosphoramidase
activity
F
NAS
SpoSPCC1442.14c
GO:0047627 adenylylsulfatase activity F
IDA
AthAt3g56490
At5g48545
GO:0006414 translational elongation P
RCA
SceS000002283
GO:0006790 sulfur metabolic process P
IDA
AthAt3g56490
At5g48545
GO:0008150 biological_process P
ND
AthAt1g31160
MmuMGI:1916167
GO:0009117 nucleotide metabolic process P
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0009150 purine ribonucleotide metabolic
process
P
IDA
AthAt3g56490
At5g48545

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC1442.14c
(O94586)
YDL125C
(S000002283)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002283
SpoSPCC1442.14c
ISS
SpoSPCC1442.14c
GO:0005737 cytoplasm C
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0005829 cytosol C
IDA
SpoSPCC1442.14c
GO:0000166 nucleotide binding F
ISS
SceS000002283
SpoSPCC1442.14c
GO:0016787 hydrolase activity F
IDA
SceS000002283
ISS
SpoSPCC1442.14c
GO:0043530 adenosine 5'-monophosphoramidase
activity
F
NAS
SpoSPCC1442.14c
GO:0006414 translational elongation P
RCA
SceS000002283
GO:0009117 nucleotide metabolic process P
IDA
SceS000002283
ISS
SpoSPCC1442.14c

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GO info in one table:

s.khadayate@ucl.ac.uk