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Search term: YDL146W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LDB17
SGD link S000002305
Alternative ID YDL146W
Description Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck
Synonyms YDL146W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4035 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE25487 GI:17543648
Drosophila melanogaster (Dme) 7290878 GI:7290878 Q9W3K6
Homo sapiens (Hsa) Hs7705266
(NCKIPSD)		 GI:7705266 Q9NZQ3
Saccharomyces cerevisiae (Sce) YDL146w
(S000002305)		 GI:6320055 Q12342
Schizosaccharomyces pombe (Spo) SPBC24C6.10c GI:19112756 O74771


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC24C6.10c
GO:0005737 cytoplasm C
IDA
SceS000002305
GO:0005829 cytosol C
IDA
SpoSPBC24C6.10c
GO:0005856 cytoskeleton C
ISS
SpoSPBC24C6.10c
GO:0005882 intermediate filament C
NAS
HsaNCKIPSD
GO:0005933 cellular bud C
IDA
SceS000002305
GO:0005935 cellular bud neck C
IDA
SceS000002305
GO:0030479 actin cortical patch C
IDA
SceS000002305
GO:0032153 cell division site C
IDA
SpoSPBC24C6.10c
GO:0051286 cell tip C
IDA
SpoSPBC24C6.10c
GO:0003674 molecular_function F
ND
SceS000002305
SpoSPBC24C6.10c
GO:0005515 protein binding F
IPI
HsaNCKIPSD
GO:0008092 cytoskeletal protein binding F
NAS
HsaNCKIPSD
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
HsaNCKIPSD
GO:0006897 endocytosis P
IMP
SceS000002305
GO:0007010 cytoskeleton organization P
ISS
SpoSPBC24C6.10c
NAS
HsaNCKIPSD
GO:0007165 signal transduction P
TAS
HsaNCKIPSD
GO:0030100 regulation of endocytosis P
ISS
SpoSPBC24C6.10c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38577

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) LDB17
(S000002305)		 GI:6320055 Q12342
Kluyveromyces lactis (Kla) KLLA0C16269g GI:50305933


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002305
GO:0005933 cellular bud C
IDA
SceS000002305
GO:0005935 cellular bud neck C
IDA
SceS000002305
GO:0030479 actin cortical patch C
IDA
SceS000002305
GO:0003674 molecular_function F
ND
SceS000002305
GO:0006897 endocytosis P
IMP
SceS000002305

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13276

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1816 ADR075W
Candida glabrata (Cgl) cgl2680 CAGL0I03696g
Cryptococcus neoformans (Cne) cne488 163.m06295
Debaryomyces hansenii (Dha) dha794 DEHA0B02563g
Kluyveromyces lactis (Kla) kla1926 KLLA0C16269g
Neurospora crassa (Ncr) ncr10337 NCU10773.2
Saccharomyces cerevisiae (Sce) sce921 YDL146W
(S000002305)
Schizosaccharomyces pombe (Spo) spo4533 SPBC24C6.10c O74771
Yarrowia lipolytica (Yli) yli2618 YALI0C22462g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC24C6.10c
GO:0005737 cytoplasm C
IDA
SceS000002305
GO:0005829 cytosol C
IDA
SpoSPBC24C6.10c
GO:0005856 cytoskeleton C
ISS
SpoSPBC24C6.10c
GO:0005933 cellular bud C
IDA
SceS000002305
GO:0005935 cellular bud neck C
IDA
SceS000002305
GO:0030479 actin cortical patch C
IDA
SceS000002305
GO:0032153 cell division site C
IDA
SpoSPBC24C6.10c
GO:0051286 cell tip C
IDA
SpoSPBC24C6.10c
GO:0003674 molecular_function F
ND
SceS000002305
SpoSPBC24C6.10c
GO:0006897 endocytosis P
IMP
SceS000002305
GO:0007010 cytoskeleton organization P
ISS
SpoSPBC24C6.10c
GO:0030100 regulation of endocytosis P
ISS
SpoSPBC24C6.10c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC24C6.10c
(O74771)		 YDL146W
(S000002305)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC24C6.10c
GO:0005737 cytoplasm C
IDA
SceS000002305
GO:0005829 cytosol C
IDA
SpoSPBC24C6.10c
GO:0005856 cytoskeleton C
ISS
SpoSPBC24C6.10c
GO:0005933 cellular bud C
IDA
SceS000002305
GO:0005935 cellular bud neck C
IDA
SceS000002305
GO:0030479 actin cortical patch C
IDA
SceS000002305
GO:0032153 cell division site C
IDA
SpoSPBC24C6.10c
GO:0051286 cell tip C
IDA
SpoSPBC24C6.10c
GO:0003674 molecular_function F
ND
SceS000002305
SpoSPBC24C6.10c
GO:0006897 endocytosis P
IMP
SceS000002305
GO:0007010 cytoskeleton organization P
ISS
SpoSPBC24C6.10c
GO:0030100 regulation of endocytosis P
ISS
SpoSPBC24C6.10c

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