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Search term: YDL147W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPN5
SGD link S000002306
Alternative ID YDL147W
Description Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p
Synonyms YDL147W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1498 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING 26S proteasome regulatory complex, subunit RPN5/PSMD12

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g09900 GI:15242545
Arabidopsis thaliana (Ath) At5g64760 GI:10177207
Caenorhabditis elegans (Cel) CE02632
(WBGene00004461)		 GI:17533097 Q19324
Drosophila melanogaster (Dme) 7296672 GI:6434942
Homo sapiens (Hsa) Hs18554904 GI:18554904
Homo sapiens (Hsa) Hs22043519 GI:22043519
Homo sapiens (Hsa) Hs4506221
(PSMD12)		 GI:4506221 O00232
Saccharomyces cerevisiae (Sce) YDL147w
(S000002306)		 GI:6320054 Q12250
Schizosaccharomyces pombe (Spo) SPAC1420.03 GI:19114190 Q9UTM3
Schizosaccharomyces pombe (Spo) SPAPB8E5.02c GI:19115688 Q9UTM3
Encephalitozoon cuniculi (Ecu) ECU05g1080 GI:19173648 Q8SVI6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
ISS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0005634 nucleus C
IDA
AthAt5g64760
At5g09900
SpoSPAC1420.03
TAS
AthAt5g64760
GO:0005635 nuclear envelope C
IDA
SpoSPAC1420.03
GO:0005737 cytoplasm C
IDA
AthAt5g64760
At5g09900
GO:0005829 cytosol C
IDA
SpoSPAC1420.03
GO:0005838 proteasome regulatory particle C
TAS
HsaPSMD12
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000002306
ISS
AthAt5g64760
At5g09900
GO:0034399 nuclear periphery C
IDA
SpoSPAPB8E5.02c
SPAC1420.03
GO:0034515 proteasome storage granule C
IDA
SceS000002306
GO:0003674 molecular_function F
ND
AthAt5g64760
At5g09900
SceS000002306
GO:0005515 protein binding F
IPI
HsaPSMD12
SpoSPAPB8E5.02c
SPAC1420.03
GO:0000003 reproduction P
IMP
CelWBGene00004461
GO:0000278 mitotic cell cycle P
IC
SpoSPAC1420.03
SPAPB8E5.02c
GO:0006508 proteolysis P
RCA
SceS000002306
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
AthAt5g64760
At5g09900
SceS000002306
GO:0007275 multicellular organismal development P
IMP
AthAt5g64760
At5g09900
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004461
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g09900
GO:0030163 protein catabolic process P
TAS
AthAt5g64760
GO:0031144 proteasome localization P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMD12
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0043248 proteasome assembly P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD12
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD12

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2109

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PSMD12 GI:4506221 O00232
Pan troglodytes (Ptr) PSMD12 GI:114670121
Canis familiaris (Cfa) PSMD12 GI:73965259
Mus musculus (Mmu) Psmd12
(MGI:1914247)		 GI:13385384 Q3TRH2
Rattus norvegicus (Rno) Psmd12
(RGD:1359305)		 GI:54400716
Gallus gallus (Gga) PSMD12 GI:71897101
Drosophila melanogaster (Dme) Rpn5
(FBgn0028690)		 GI:21357319
Anopheles gambiae (Aga) AgaP_AGAP005535 GI:158294332
Caenorhabditis elegans (Cel) rpn-5
(CE02632;
WBGene00004461)		 GI:17533097 Q19324
Schizosaccharomyces pombe (Spo) rpn5
(SPAC1420.03)		 GI:19115688 Q9UTM3
Schizosaccharomyces pombe (Spo) rpn5
(SPAC1420.03)		 GI:19114190 Q9UTM3
Saccharomyces cerevisiae (Sce) RPN5
(S000002306)		 GI:6320054 Q12250
Kluyveromyces lactis (Kla) KLLA0C16313g GI:50305937
Eremothecium gossypii (Ego) AGOS_ADR073W GI:45187946
Magnaporthe grisea (Mgr) MGG_02608 GI:39970283
Neurospora crassa (Ncr) NCU02650.1 GI:32422811
Arabidopsis thaliana (Ath) RPN5B GI:79332227
Arabidopsis thaliana (Ath) EMB2107 GI:42573323
Oryza sativa (Osa) Os03g0851300 GI:115456627
Plasmodium falciparum (Pfa) PF10_0174 GI:124802396


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
ISS
SpoSPAC1420.03
GO:0005575 cellular_component C
ND
MmuMGI:1914247
GO:0005634 nucleus C
IDA
AthEMB2107
RPN5B
SpoSPAC1420.03
TAS
AthRPN5B
GO:0005635 nuclear envelope C
IDA
SpoSPAC1420.03
GO:0005737 cytoplasm C
IDA
AthEMB2107
RPN5B
GO:0005829 cytosol C
IDA
SpoSPAC1420.03
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0028690
ISS
DmeFBgn0028690
PfaPF10_0174
TAS
HsaPSMD12
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000002306
ISS
AthEMB2107
RPN5B
DmeFBgn0028690
NAS
DmeFBgn0028690
GO:0034399 nuclear periphery C
IDA
SpoSPAC1420.03
GO:0034515 proteasome storage granule C
IDA
SceS000002306
GO:0003674 molecular_function F
ND
AthEMB2107
RPN5B
MmuMGI:1914247
SceS000002306
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0028690
ISS
PfaPF10_0174
GO:0005515 protein binding F
IPI
HsaPSMD12
SpoSPAC1420.03
GO:0000003 reproduction P
IMP
CelWBGene00004461
GO:0000278 mitotic cell cycle P
IC
SpoSPAC1420.03
GO:0006508 proteolysis P
IDA
DmeFBgn0028690
ISS
DmeFBgn0028690
RCA
SceS000002306
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
PfaPF10_0174
TAS
AthEMB2107
RPN5B
SceS000002306
GO:0007275 multicellular organismal development P
IMP
AthEMB2107
RPN5B
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAC1420.03
GO:0008150 biological_process P
ND
MmuMGI:1914247
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004461
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthEMB2107
GO:0030163 protein catabolic process P
TAS
AthRPN5B
GO:0031144 proteasome localization P
IGI
SpoSPAC1420.03
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMD12
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IGI
SpoSPAC1420.03
GO:0043248 proteasome assembly P
IGI
SpoSPAC1420.03
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD12
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMD12

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1689

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga946 ENSANGP00000021809
Anopheles gambiae (Aga) aga947 ENSANGP00000025808
Ashbya gossypii (Ago) ago1814 ADR073W
Arabidopsis thaliana (Ath) ath23186 At5g09900.1
Arabidopsis thaliana (Ath) ath23187 At5g09900.2
Arabidopsis thaliana (Ath) ath28619 At5g64760.1
Caenorhabditis elegans (Cel) cel5969 F10G7.8
(CE02632;
WBGene00004461)
Candida glabrata (Cgl) cgl2679 CAGL0I03674g
Cryptococcus neoformans (Cne) cne835 163.m06165
Dictyostelium discoideum (Ddi) ddi4576 DDB0203976
Debaryomyces hansenii (Dha) dha2971 DEHA0D15004g
Drosophila melanogaster (Dme) dme11121 CG1100-PA
(FBgn0028690)
Danio rerio (Dre) dre31542 ENSDARP00000036983
Encephalitozoon cuniculi (Ecu) ecu1210 19173648
Takifugu rubripes (Fru) fru14874 SINFRUP00000127955
Gallus gallus (Gga) gga8545 ENSGALP00000005854
(PSMD12)		 Q5ZI37
Gallus gallus (Gga) gga8546 ENSGALP00000005855
Homo sapiens (Hsa) hsa14210 ENSP00000348442
(PSMD12)		 O00232
Homo sapiens (Hsa) hsa14209 ENSP00000349667
(PSMD12)		 A6NP15
Kluyveromyces lactis (Kla) kla1928 KLLA0C16313g
Mus musculus (Mmu) mmu5034 ENSMUSP00000021063
(MGI:1914247)		 Q3U8F5
Neurospora crassa (Ncr) ncr2566 NCU02650.2
Oryza sativa (Osa) osa54076 6301.m00188
Plasmodium falciparum (Pfa) pfa395 PF10_0174
Rattus norvegicus (Rno) rno6327 ENSRNOP00000004283
(RGD:1359305)		 Q5XIC6
Saccharomyces cerevisiae (Sce) sce922 YDL147W
(S000002306)
Schizosaccharomyces pombe (Spo) spo190 SPAC1420.03 Q9UTM3
Schizosaccharomyces pombe (Spo) spo3702 SPAPB8E5.02c Q9UTM3
Yarrowia lipolytica (Yli) yli3123 YALI0D09977g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
ISS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0005575 cellular_component C
ND
MmuMGI:1914247
GO:0005634 nucleus C
IDA
AthAt5g64760
At5g09900
SpoSPAC1420.03
TAS
AthAt5g64760
GO:0005635 nuclear envelope C
IDA
SpoSPAC1420.03
GO:0005737 cytoplasm C
IDA
AthAt5g64760
At5g09900
GO:0005829 cytosol C
IDA
SpoSPAC1420.03
GO:0005838 proteasome regulatory particle C
IDA
DmeFBgn0028690
ISS
DmeFBgn0028690
PfaPF10_0174
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000002306
ISS
AthAt5g64760
At5g09900
DmeFBgn0028690
NAS
DmeFBgn0028690
GO:0034399 nuclear periphery C
IDA
SpoSPAPB8E5.02c
SPAC1420.03
GO:0034515 proteasome storage granule C
IDA
SceS000002306
GO:0003674 molecular_function F
ND
AthAt5g64760
At5g09900
MmuMGI:1914247
SceS000002306
GO:0004175 endopeptidase activity F
IDA
DmeFBgn0028690
ISS
PfaPF10_0174
GO:0005515 protein binding F
IPI
SpoSPAPB8E5.02c
SPAC1420.03
GO:0000003 reproduction P
IMP
CelWBGene00004461
GO:0000278 mitotic cell cycle P
IC
SpoSPAC1420.03
SPAPB8E5.02c
GO:0006508 proteolysis P
IDA
DmeFBgn0028690
ISS
DmeFBgn0028690
RCA
SceS000002306
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
PfaPF10_0174
TAS
AthAt5g64760
At5g09900
SceS000002306
GO:0007275 multicellular organismal development P
IMP
AthAt5g64760
At5g09900
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0008150 biological_process P
ND
MmuMGI:1914247
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004461
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g09900
GO:0030163 protein catabolic process P
TAS
AthAt5g64760
GO:0031144 proteasome localization P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0043248 proteasome assembly P
IGI
SpoSPAC1420.03
SPAPB8E5.02c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAPB8E5.02c
(Q9UTM3)		 YDL147W
(S000002306)
SPAC1420.03
(Q9UTM3)		 YDL147W
(S000002306)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
ISS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0005634 nucleus C
IDA
SpoSPAC1420.03
GO:0005635 nuclear envelope C
IDA
SpoSPAC1420.03
GO:0005829 cytosol C
IDA
SpoSPAC1420.03
GO:0008541 proteasome regulatory particle, lid
subcomplex		 C
IDA
SceS000002306
GO:0034399 nuclear periphery C
IDA
SpoSPAPB8E5.02c
SPAC1420.03
GO:0034515 proteasome storage granule C
IDA
SceS000002306
GO:0003674 molecular_function F
ND
SceS000002306
GO:0005515 protein binding F
IPI
SpoSPAPB8E5.02c
SPAC1420.03
GO:0000278 mitotic cell cycle P
IC
SpoSPAC1420.03
SPAPB8E5.02c
GO:0006508 proteolysis P
RCA
SceS000002306
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
SceS000002306
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPAPB8E5.02c
SPAC1420.03
GO:0031144 proteasome localization P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IGI
SpoSPAC1420.03
SPAPB8E5.02c
GO:0043248 proteasome assembly P
IGI
SpoSPAC1420.03
SPAPB8E5.02c

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