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Search term: YDL154W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSH5
SGD link S000002313
Alternative ID YDL154W
Description Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans
Synonyms YDL154W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0221 AC-HY--

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Mismatch repair ATPase MSH5 (MutS family)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g20475 GI:15231147
Caenorhabditis elegans (Cel) CE26678
(WBGene00003421)		 GI:17539736 Q19272
Homo sapiens (Hsa) Hs21361940 GI:5725250
Homo sapiens (Hsa) Hs4505253 GI:4505253 O43196
Saccharomyces cerevisiae (Sce) YDL154w
(S000002313)		 GI:6320047 Q12175
Arabidopsis thaliana (Ath) At3g20475 GI:15231147
Caenorhabditis elegans (Cel) CE26678
(WBGene00003421)		 GI:17539736 Q19272
Homo sapiens (Hsa) Hs21361940 GI:5725250
Homo sapiens (Hsa) Hs4505253 GI:4505253 O43196
Saccharomyces cerevisiae (Sce) YDL154w
(S000002313)		 GI:6320047 Q12175
Arabidopsis thaliana (Ath) At3g20475 GI:15231147
Caenorhabditis elegans (Cel) CE26678
(WBGene00003421)		 GI:17539736 Q19272
Homo sapiens (Hsa) Hs21361940 GI:5725250
Homo sapiens (Hsa) Hs4505253 GI:4505253 O43196
Saccharomyces cerevisiae (Sce) YDL154w
(S000002313)		 GI:6320047 Q12175


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
AthAt3g20475
GO:0005634 nucleus C
IDA
SceS000002313
GO:0003674 molecular_function F
ND
SceS000002313
GO:0003684 damaged DNA binding F
ISS
AthAt3g20475
GO:0005524 ATP binding F
ISS
AthAt3g20475
GO:0006298 mismatch repair P
ISS
AthAt3g20475
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt3g20475
CelWBGene00003421
SceS000002313
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003421
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00003421
GO:0051026 chiasma assembly P
IMP
AthAt3g20475
CelWBGene00003421

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104073

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MSH5
(S000002313)		 GI:6320047 Q12175
Kluyveromyces lactis (Kla) KLLA0C16423g GI:50305947
Magnaporthe grisea (Mgr) MGG_05639 GI:145615504
Neurospora crassa (Ncr) NCU09384.1 GI:32423277


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002313
GO:0003674 molecular_function F
ND
SceS000002313
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000002313

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4362

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4857 ENSANGP00000002901
Arabidopsis thaliana (Ath) ath14342 At3g20475.1
Caenorhabditis elegans (Cel) cel5800 F09E8.3
(CE26678;
WBGene00003421)
Candida glabrata (Cgl) cgl2675 CAGL0I03586g
Cryptococcus neoformans (Cne) cne2265 181.m08290
Dictyostelium discoideum (Ddi) ddi13208 DDB0231220
Danio rerio (Dre) dre6198 ENSDARP00000019855
Takifugu rubripes (Fru) fru7011 SINFRUP00000161087
Gallus gallus (Gga) gga24302 ENSGALP00000004306
(LOC776972)
Homo sapiens (Hsa) hsa26850 ENSP00000266123
Kluyveromyces lactis (Kla) kla1933 KLLA0C16423g
Mus musculus (Mmu) mmu11526 ENSMUSP00000007250
(MGI:1329021)		 Q9QUM7
Mus musculus (Mmu) mmu11525 ENSMUSP00000055863
Neurospora crassa (Ncr) ncr9143 NCU09384.2
Rattus norvegicus (Rno) rno17444 ENSRNOP00000001143
Saccharomyces cerevisiae (Sce) sce929 YDL154W
(S000002313)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IDA
AthAt3g20475
GO:0000795 synaptonemal complex C
IDA
MmuMGI:1329021
GO:0005634 nucleus C
IDA
SceS000002313
GO:0003674 molecular_function F
ND
SceS000002313
GO:0003684 damaged DNA binding F
ISS
AthAt3g20475
GO:0005524 ATP binding F
ISS
AthAt3g20475
GO:0006298 mismatch repair P
ISS
AthAt3g20475
GO:0007127 meiosis I P
IMP
MmuMGI:1329021
GO:0007129 synapsis P
IMP
MmuMGI:1329021
GO:0007131 reciprocal meiotic recombination P
IMP
AthAt3g20475
CelWBGene00003421
SceS000002313
GO:0007292 female gamete generation P
IMP
MmuMGI:1329021
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003421
GO:0045143 homologous chromosome segregation P
IMP
CelWBGene00003421
GO:0051026 chiasma assembly P
IMP
AthAt3g20475
CelWBGene00003421

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