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Search term: YDL185W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TFP1
SGD link S000002344
Alternative ID YDL185W
Description Subunit A of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease
Synonyms YDL185W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1352 ACDHYPE

KOGs classification KOGs description
METABOLISM Vacuolar H+-ATPase V1 sector, subunit A

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g16820_2 GI:15219366
Arabidopsis thaliana (Ath) At1g78900 GI:15219234
Caenorhabditis elegans (Cel) CE22210
(WBGene00013025)		 GI:17565854 Q9XW92
Drosophila melanogaster (Dme) 7297989 GI:7297989 A4V0N4
Drosophila melanogaster (Dme) 7297992 GI:20129479
Drosophila melanogaster (Dme) 7297994 GI:12643429
Homo sapiens (Hsa) HsM4502307 GI:4502307
Homo sapiens (Hsa) Hs19913424
(ATP6V1A)		 GI:19913424 P38606
Saccharomyces cerevisiae (Sce) YDL185w
(S000002344)		 GI:6320016 P17255
Schizosaccharomyces pombe (Spo) SPAC343.05 GI:19114337 P31406
Encephalitozoon cuniculi (Ecu) ECU11g1280i GI:19074928 Q8SQU9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
SpoSPAC343.05
TAS
SceS000002344
GO:0000325 plant-type vacuole C
IDA
AthAt1g78900
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002344
GO:0005618 cell wall C
IDA
AthAt1g78900
GO:0005773 vacuole C
IDA
AthAt1g78900
At1g16820
GO:0005774 vacuolar membrane C
IDA
AthAt1g78900
GO:0005829 cytosol C
IDA
SpoSPAC343.05
ISS
HsaATP6V1A
GO:0005886 plasma membrane C
IDA
AthAt1g16820
At1g78900
ISS
HsaATP6V1A
GO:0005887 integral to plasma membrane C
TAS
HsaATP6V1A
GO:0009507 chloroplast C
IDA
AthAt1g78900
GO:0009941 chloroplast envelope C
IDA
AthAt1g78900
GO:0016020 membrane C
IDA
AthAt1g78900
GO:0016469 proton-transporting two-sector ATPase
complex		 C
TAS
HsaATP6V1A
GO:0004520 endodeoxyribonuclease activity F
TAS
SceS000002344
GO:0005524 ATP binding F
ISS
AthAt1g78900
SpoSPAC343.05
GO:0046933 hydrogen ion transporting ATP synthase activity,
rotational mechanism		 F
ISS
AthAt1g78900
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
TAS
SceS000002344
SpoSPAC343.05
GO:0000003 reproduction P
IMP
CelWBGene00013025
GO:0002119 nematode larval development P
IMP
CelWBGene00013025
GO:0006200 ATP catabolic process P
TAS
SpoSPAC343.05
GO:0006314 intron homing P
TAS
SceS000002344
GO:0006810 transport P
TAS
HsaATP6V1A
GO:0006811 ion transport P
RCA
SceS000002344
GO:0006897 endocytosis P
IMP
SpoSPAC343.05
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00013025
GO:0007030 Golgi organization P
IMP
AthAt1g78900
GO:0007035 vacuolar acidification P
IMP
SceS000002344
SpoSPAC343.05
GO:0009117 nucleotide metabolic process P
RCA
SceS000002344
GO:0009555 pollen development P
IMP
AthAt1g78900
GO:0009651 response to salt stress P
IEP
AthAt1g78900
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00013025
GO:0015991 ATP hydrolysis coupled proton transport P
ISS
SpoSPAC343.05
GO:0015992 proton transport P
ISS
AthAt1g78900
GO:0040007 growth P
IMP
CelWBGene00013025
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00013025
GO:0040011 locomotion P
IMP
CelWBGene00013025
GO:0044267 cellular protein metabolic process P
IDA
SceS000002344
GO:0050801 ion homeostasis P
RCA
SceS000002344

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1277

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ATP6V1A GI:19913424 P38606
Pan troglodytes (Ptr) ATP6V1A GI:114588549
Canis familiaris (Cfa) ATP6V1A GI:57109638
Mus musculus (Mmu) Atp6v1a
(MGI:1201780)		 GI:31560731 P50516
Rattus norvegicus (Rno) Atp6v1a GI:109493236
Gallus gallus (Gga) ATP6V1A GI:45384462
Drosophila melanogaster (Dme) Vha68-2
(FBgn0020367)		 GI:24583984
Anopheles gambiae (Aga) AgaP_AGAP003153 GI:31207753
Caenorhabditis elegans (Cel) vha-13
(CE22210;
WBGene00013025)		 GI:17565854 Q9XW92
Schizosaccharomyces pombe (Spo) vma1
(SPAC343.05)		 GI:19114337 P31406
Saccharomyces cerevisiae (Sce) TFP1
(S000002344)		 GI:6320016 P17255
Kluyveromyces lactis (Kla) KLLA0F05401g GI:50310611
Magnaporthe grisea (Mgr) MGG_08087 GI:145612087
Neurospora crassa (Ncr) NCU01207.1 GI:32412440
Arabidopsis thaliana (Ath) VHA-A GI:15219234
Oryza sativa (Osa) Os02g0175400 GI:115444549
Oryza sativa (Osa) Os06g0662000 GI:115469362
Plasmodium falciparum (Pfa) PF13_0065 GI:124512982


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
DmeFBgn0020367
PfaPF13_0065
SpoSPAC343.05
NAS
DmeFBgn0020367
TAS
SceS000002344
GO:0000325 plant-type vacuole C
IDA
AthVHA-A
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002344
GO:0005618 cell wall C
IDA
AthVHA-A
GO:0005739 mitochondrion C
IDA
AthVHA-A
MmuMGI:1201780
GO:0005773 vacuole C
IDA
AthVHA-A
GO:0005774 vacuolar membrane C
IDA
AthVHA-A
GO:0005829 cytosol C
IDA
MmuMGI:1201780
SpoSPAC343.05
ISS
HsaATP6V1A
GO:0005886 plasma membrane C
IDA
AthVHA-A
DmeFBgn0020367
MmuMGI:1201780
ISS
HsaATP6V1A
GO:0005887 integral to plasma membrane C
TAS
HsaATP6V1A
GO:0009507 chloroplast C
IDA
AthVHA-A
GO:0009705 plant-type vacuole membrane C
IDA
AthVHA-A
GO:0009941 chloroplast envelope C
IDA
AthVHA-A
GO:0012510 trans-Golgi network transport vesicle
membrane		 C
IDA
AthVHA-A
GO:0016020 membrane C
IDA
AthVHA-A
GO:0016469 proton-transporting two-sector ATPase
complex		 C
TAS
HsaATP6V1A
GO:0003674 molecular_function F
ND
MmuMGI:1201780
GO:0004520 endodeoxyribonuclease activity F
TAS
SceS000002344
GO:0005524 ATP binding F
ISS
AthVHA-A
SpoSPAC343.05
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
ISS
DmeFBgn0020367
NAS
DmeFBgn0020367
GO:0009678 hydrogen-translocating pyrophosphatase
activity		 F
IDA
AthVHA-A
GO:0016887 ATPase activity F
ISS
AthVHA-A
GO:0046933 hydrogen ion transporting ATP synthase activity,
rotational mechanism		 F
ISS
AthVHA-A
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
TAS
SceS000002344
SpoSPAC343.05
GO:0000003 reproduction P
IMP
CelWBGene00013025
GO:0002119 nematode larval development P
IMP
CelWBGene00013025
GO:0006200 ATP catabolic process P
TAS
SpoSPAC343.05
GO:0006314 intron homing P
TAS
SceS000002344
GO:0006810 transport P
TAS
HsaATP6V1A
GO:0006811 ion transport P
RCA
SceS000002344
GO:0006897 endocytosis P
IMP
SpoSPAC343.05
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00013025
GO:0007030 Golgi organization P
IMP
AthVHA-A
GO:0007035 vacuolar acidification P
IMP
SceS000002344
SpoSPAC343.05
ISS
PfaPF13_0065
GO:0008150 biological_process P
ND
MmuMGI:1201780
GO:0009117 nucleotide metabolic process P
RCA
SceS000002344
GO:0009555 pollen development P
IMP
AthVHA-A
GO:0009651 response to salt stress P
IEP
AthVHA-A
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00013025
GO:0015986 ATP synthesis coupled proton transport P
IDA
AthVHA-A
GO:0015991 ATP hydrolysis coupled proton transport P
ISS
PfaPF13_0065
SpoSPAC343.05
GO:0015992 proton transport P
ISS
AthVHA-A
GO:0031669 cellular response to nutrient levels P
IGI
AthVHA-A
GO:0040007 growth P
IMP
CelWBGene00013025
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00013025
GO:0040011 locomotion P
IMP
CelWBGene00013025
GO:0044267 cellular protein metabolic process P
IDA
SceS000002344
GO:0050801 ion homeostasis P
RCA
SceS000002344

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_937

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5441 ENSANGP00000024697
Ashbya gossypii (Ago) ago1843 ADR102W
Arabidopsis thaliana (Ath) ath7246 At1g78900.1
Caenorhabditis elegans (Cel) cel19329 Y49A3A.2
(CE22210;
WBGene00013025)
Candida glabrata (Cgl) cgl2692 CAGL0I03960g
Cryptococcus neoformans (Cne) cne3063 167.m03367
Dictyostelium discoideum (Ddi) ddi12798 DDB0201563
Debaryomyces hansenii (Dha) dha3050 DEHA0D16731g
Drosophila melanogaster (Dme) dme2200 CG12403-PA
(FBgn0020368)
Drosophila melanogaster (Dme) dme2195 CG3762-PA
(FBgn0020367)
Drosophila melanogaster (Dme) dme2196 CG3762-PB
(FBgn0020367)
Drosophila melanogaster (Dme) dme2197 CG3762-PC
(FBgn0020367)
Drosophila melanogaster (Dme) dme2198 CG5075-PA
(FBgn0032464)
Danio rerio (Dre) dre18871 ENSDARP00000017306
Danio rerio (Dre) dre18870 ENSDARP00000049002
(atp6v1al)		 Q7SY46
Encephalitozoon cuniculi (Ecu) ecu1016 19074928
Takifugu rubripes (Fru) fru5766 SINFRUP00000158538
Takifugu rubripes (Fru) fru25730 SINFRUP00000159433
Gallus gallus (Gga) gga1665 ENSGALP00000023849
(ATP6V1A)		 Q90647-1
Gallus gallus (Gga) gga1666 ENSGALP00000023850
(ATP6V1A)		 Q90647-2
Homo sapiens (Hsa) hsa22935 ENSP00000273398
(ATP6V1A)		 P38606
Kluyveromyces lactis (Kla) kla4325 KLLA0F05401g
Mus musculus (Mmu) mmu10358 ENSMUSP00000066886
(MGI:1201780)		 P50516-1
Neurospora crassa (Ncr) ncr1170 NCU01207.2
Oryza sativa (Osa) osa5692 2419.m00154
Oryza sativa (Osa) osa23620 3775.m00202
Oryza sativa (Osa) osa55424 6158.m00173
Plasmodium falciparum (Pfa) pfa4199 PF13_0065
Rattus norvegicus (Rno) rno7135 ENSRNOP00000002727
(RGD:1596464)
Saccharomyces cerevisiae (Sce) sce964 YDL185W
(S000002344)
Schizosaccharomyces pombe (Spo) spo2259 SPAC343.05 P31406
Yarrowia lipolytica (Yli) yli329 YALI0A09900g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
DmeFBgn0020367
FBgn0020368
FBgn0032464
PfaPF13_0065
SpoSPAC343.05
NAS
DmeFBgn0020367
FBgn0020368
TAS
SceS000002344
GO:0000325 plant-type vacuole C
IDA
AthAt1g78900
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002344
GO:0005618 cell wall C
IDA
AthAt1g78900
GO:0005739 mitochondrion C
IDA
MmuMGI:1201780
GO:0005773 vacuole C
IDA
AthAt1g78900
GO:0005774 vacuolar membrane C
IDA
AthAt1g78900
GO:0005829 cytosol C
IDA
MmuMGI:1201780
SpoSPAC343.05
GO:0005886 plasma membrane C
IDA
AthAt1g78900
DmeFBgn0020367
FBgn0020368
MmuMGI:1201780
GO:0009507 chloroplast C
IDA
AthAt1g78900
GO:0009941 chloroplast envelope C
IDA
AthAt1g78900
GO:0016020 membrane C
IDA
AthAt1g78900
GO:0003674 molecular_function F
ND
MmuMGI:1201780
GO:0004520 endodeoxyribonuclease activity F
TAS
SceS000002344
GO:0005524 ATP binding F
ISS
AthAt1g78900
SpoSPAC343.05
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
ISS
DmeFBgn0020367
FBgn0032464
FBgn0020368
NAS
DmeFBgn0020367
FBgn0020368
GO:0046933 hydrogen ion transporting ATP synthase activity,
rotational mechanism		 F
ISS
AthAt1g78900
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
TAS
SceS000002344
SpoSPAC343.05
GO:0000003 reproduction P
IMP
CelWBGene00013025
GO:0002119 nematode larval development P
IMP
CelWBGene00013025
GO:0006200 ATP catabolic process P
TAS
SpoSPAC343.05
GO:0006314 intron homing P
TAS
SceS000002344
GO:0006811 ion transport P
RCA
SceS000002344
GO:0006897 endocytosis P
IMP
SpoSPAC343.05
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00013025
GO:0007030 Golgi organization P
IMP
AthAt1g78900
GO:0007035 vacuolar acidification P
IMP
SceS000002344
SpoSPAC343.05
ISS
PfaPF13_0065
GO:0008150 biological_process P
ND
MmuMGI:1201780
GO:0009117 nucleotide metabolic process P
RCA
SceS000002344
GO:0009555 pollen development P
IMP
AthAt1g78900
GO:0009651 response to salt stress P
IEP
AthAt1g78900
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00013025
GO:0015991 ATP hydrolysis coupled proton transport P
ISS
PfaPF13_0065
SpoSPAC343.05
GO:0015992 proton transport P
ISS
AthAt1g78900
NAS
DmeFBgn0020368
GO:0040007 growth P
IMP
CelWBGene00013025
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00013025
GO:0040011 locomotion P
IMP
CelWBGene00013025
GO:0044267 cellular protein metabolic process P
IDA
SceS000002344
GO:0050801 ion homeostasis P
RCA
SceS000002344

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC343.05
(P31406)		 YDL185W
(S000002344)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000221 vacuolar proton-transporting V-type ATPase, V1
domain		 C
ISS
SpoSPAC343.05
TAS
SceS000002344
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002344
GO:0005829 cytosol C
IDA
SpoSPAC343.05
GO:0004520 endodeoxyribonuclease activity F
TAS
SceS000002344
GO:0005524 ATP binding F
ISS
SpoSPAC343.05
GO:0046961 proton-transporting ATPase activity, rotational
mechanism		 F
TAS
SceS000002344
SpoSPAC343.05
GO:0006200 ATP catabolic process P
TAS
SpoSPAC343.05
GO:0006314 intron homing P
TAS
SceS000002344
GO:0006811 ion transport P
RCA
SceS000002344
GO:0006897 endocytosis P
IMP
SpoSPAC343.05
GO:0007035 vacuolar acidification P
IMP
SceS000002344
SpoSPAC343.05
GO:0009117 nucleotide metabolic process P
RCA
SceS000002344
GO:0015991 ATP hydrolysis coupled proton transport P
ISS
SpoSPAC343.05
GO:0044267 cellular protein metabolic process P
IDA
SceS000002344
GO:0050801 ion homeostasis P
RCA
SceS000002344

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