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Search term: YDL216C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RRI1
SGD link S000002375
Alternative ID YDL216C
Description Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling
Synonyms YDL216C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1554 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING COP9 signalosome, subunit CSN5

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g22920 GI:15219970
Arabidopsis thaliana (Ath) At1g71230 GI:15224003
Caenorhabditis elegans (Cel) CE06722
(WBGene00000817)		 GI:17538322 P91001
Drosophila melanogaster (Dme) 7300154
(FBgn0027053)		 GI:17137694
Homo sapiens (Hsa) Hs5803046 GI:5803046
Homo sapiens (Hsa) Hs17463759 GI:17463759
Saccharomyces cerevisiae (Sce) YDL216c
(S000002375)		 GI:6319985
Schizosaccharomyces pombe (Spo) SPAC1687.13c GI:19114043 O94454


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
CelWBGene00000817
SpoSPAC1687.13c
GO:0005737 cytoplasm C
IDA
CelWBGene00000817
DmeFBgn0027053
GO:0005829 cytosol C
IDA
SpoSPAC1687.13c
GO:0008180 signalosome C
IDA
DmeFBgn0027053
SceS000002375
SpoSPAC1687.13c
IMP
DmeFBgn0027053
IPI
AthAt1g71230
At1g22920
ISS
CelWBGene00000817
DmeFBgn0027053
NAS
DmeFBgn0027053
TAS
AthAt1g71230
At1g22920
DmeFBgn0027053
GO:0031672 A band C
IDA
CelWBGene00000817
GO:0003674 molecular_function F
ND
AthAt1g22920
GO:0004222 metalloendopeptidase activity F
IMP
SceS000002375
GO:0005515 protein binding F
IPI
AthAt1g71230
CelWBGene00000817
DmeFBgn0027053
GO:0008022 protein C-terminus binding F
IPI
CelWBGene00000817
GO:0017151 DEAD/H-box RNA helicase binding F
IPI
CelWBGene00000817
GO:0019781 NEDD8 activating enzyme activity F
IMP
DmeFBgn0027053
GO:0000003 reproduction P
IMP
CelWBGene00000817
GO:0000085 G2 phase of mitotic cell cycle P
IMP
AthAt1g71230
At1g22920
GO:0000338 protein deneddylation P
IGI
AthAt1g71230
IMP
DmeFBgn0027053
TAS
AthAt1g22920
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000002375
GO:0000910 cytokinesis P
IMP
CelWBGene00000817
GO:0001751 compound eye photoreceptor cell
differentiation		 P
IMP
DmeFBgn0027053
TAS
DmeFBgn0027053
GO:0002119 nematode larval development P
IMP
CelWBGene00000817
GO:0006914 autophagy P
RCA
SceS000002375
GO:0007049 cell cycle P
NAS
SpoSPAC1687.13c
GO:0007275 multicellular organismal development P
IMP
DmeFBgn0027053
GO:0007310 oocyte dorsal/ventral axis specification P
IMP
DmeFBgn0027053
GO:0007314 oocyte anterior/posterior axis
specification		 P
IMP
DmeFBgn0027053
GO:0007409 axonogenesis P
IMP
DmeFBgn0027053
GO:0008347 glial cell migration P
IMP
DmeFBgn0027053
GO:0008406 gonad development P
IMP
CelWBGene00000817
GO:0009640 photomorphogenesis P
TAS
AthAt1g71230
At1g22920
GO:0009733 response to auxin stimulus P
IGI
AthAt1g71230
At1g22920
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000817
GO:0009966 regulation of signal transduction P
RCA
SceS000002375
GO:0010093 specification of floral organ identity P
IMP
AthAt1g22920
GO:0010100 negative regulation of photomorphogenesis P
IGI
AthAt1g22920
At1g71230
GO:0010387 signalosome assembly P
IMP
AthAt1g71230
At1g22920
GO:0010388 cullin deneddylation P
IGI
SpoSPAC1687.13c
IMP
AthAt1g22920
SceS000002375
GO:0032434 regulation of proteasomal ubiquitin-dependent
protein catabolic process		 P
NAS
SpoSPAC1687.13c
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process		 P
IMP
DmeFBgn0027053
GO:0040007 growth P
IMP
CelWBGene00000817
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000817
GO:0045787 positive regulation of cell cycle P
IMP
DmeFBgn0027053
GO:0048477 oogenesis P
IMP
CelWBGene00000817
TAS
DmeFBgn0027053
GO:0050821 protein stabilization P
IMP
DmeFBgn0027053

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48582

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RRI1
(S000002375)		 GI:93117369
Kluyveromyces lactis (Kla) KLLA0D08503g GI:50306931
Eremothecium gossypii (Ego) AGOS_ABL146C GI:45185084


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0008180 signalosome C
IDA
SceS000002375
GO:0004222 metalloendopeptidase activity F
IMP
SceS000002375
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000002375
GO:0006914 autophagy P
RCA
SceS000002375
GO:0009966 regulation of signal transduction P
RCA
SceS000002375
GO:0010388 cullin deneddylation P
IMP
SceS000002375

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2927

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5107 ENSANGP00000018752
Ashbya gossypii (Ago) ago446 ABL146C
Arabidopsis thaliana (Ath) ath2463 At1g22920.1
Arabidopsis thaliana (Ath) ath2464 At1g22920.2
Arabidopsis thaliana (Ath) ath6409 At1g71230.1
Caenorhabditis elegans (Cel) cel612 B0547.1
(CE06722;
WBGene00000817)
Candida glabrata (Cgl) cgl1869 CAGL0G05676g
Cryptococcus neoformans (Cne) cne4096 185.m02771
Dictyostelium discoideum (Ddi) ddi8391 DDB0186089
Debaryomyces hansenii (Dha) dha4560 DEHA0F03872g
Drosophila melanogaster (Dme) dme12938 CG14884-PA
(FBgn0027053)
Danio rerio (Dre) dre16276 ENSDARP00000018898
Takifugu rubripes (Fru) fru13627 SINFRUP00000155191
Gallus gallus (Gga) gga27287 ENSGALP00000023379
(COPS5)		 Q5ZLC3
Homo sapiens (Hsa) hsa30381 ENSP00000262212
Homo sapiens (Hsa) hsa30380 ENSP00000350512
(COPS5)		 Q92905
Kluyveromyces lactis (Kla) kla2440 KLLA0D08503g
Mus musculus (Mmu) mmu34 ENSMUSP00000027050
(MGI:1349415)		 O35864
Neurospora crassa (Ncr) ncr453 NCU00467.2
Oryza sativa (Osa) osa4407 2230.m00120
Oryza sativa (Osa) osa45269 5383.m00138
Rattus norvegicus (Rno) rno22634 ENSRNOP00000008877
(RGD:1310301)		 Q4KM69
Saccharomyces cerevisiae (Sce) sce995 YDL216C
(S000002375)
Schizosaccharomyces pombe (Spo) spo3867 SPAC1687.13c O94454
Yarrowia lipolytica (Yli) yli4063 YALI0E04829g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
CelWBGene00000817
SpoSPAC1687.13c
GO:0005667 transcription factor complex C
TAS
MmuMGI:1349415
GO:0005737 cytoplasm C
IDA
CelWBGene00000817
DmeFBgn0027053
GO:0005829 cytosol C
IDA
SpoSPAC1687.13c
GO:0008180 signalosome C
IDA
DmeFBgn0027053
MmuMGI:1349415
SceS000002375
SpoSPAC1687.13c
IMP
DmeFBgn0027053
IPI
AthAt1g71230
At1g22920
ISS
CelWBGene00000817
DmeFBgn0027053
NAS
DmeFBgn0027053
TAS
AthAt1g71230
At1g22920
DmeFBgn0027053
GO:0031672 A band C
IDA
CelWBGene00000817
GO:0003674 molecular_function F
ND
AthAt1g22920
GO:0003713 transcription coactivator activity F
TAS
MmuMGI:1349415
GO:0004222 metalloendopeptidase activity F
IMP
SceS000002375
GO:0005515 protein binding F
IPI
AthAt1g71230
CelWBGene00000817
DmeFBgn0027053
MmuMGI:1349415
GO:0008022 protein C-terminus binding F
IPI
CelWBGene00000817
GO:0017151 DEAD/H-box RNA helicase binding F
IPI
CelWBGene00000817
GO:0019781 NEDD8 activating enzyme activity F
IMP
DmeFBgn0027053
GO:0000003 reproduction P
IMP
CelWBGene00000817
GO:0000085 G2 phase of mitotic cell cycle P
IMP
AthAt1g71230
At1g22920
GO:0000338 protein deneddylation P
IGI
AthAt1g71230
IMP
DmeFBgn0027053
TAS
AthAt1g22920
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000002375
GO:0000910 cytokinesis P
IMP
CelWBGene00000817
GO:0001751 compound eye photoreceptor cell
differentiation		 P
IMP
DmeFBgn0027053
TAS
DmeFBgn0027053
GO:0002119 nematode larval development P
IMP
CelWBGene00000817
GO:0006355 regulation of transcription, DNA-dependent P
TAS
MmuMGI:1349415
GO:0006914 autophagy P
RCA
SceS000002375
GO:0007049 cell cycle P
NAS
SpoSPAC1687.13c
GO:0007275 multicellular organismal development P
IMP
DmeFBgn0027053
GO:0007310 oocyte dorsal/ventral axis specification P
IMP
DmeFBgn0027053
GO:0007314 oocyte anterior/posterior axis
specification		 P
IMP
DmeFBgn0027053
GO:0007409 axonogenesis P
IMP
DmeFBgn0027053
GO:0008347 glial cell migration P
IMP
DmeFBgn0027053
GO:0008406 gonad development P
IMP
CelWBGene00000817
GO:0009640 photomorphogenesis P
TAS
AthAt1g71230
At1g22920
GO:0009733 response to auxin stimulus P
IGI
AthAt1g71230
At1g22920
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000817
GO:0009966 regulation of signal transduction P
RCA
SceS000002375
GO:0010093 specification of floral organ identity P
IMP
AthAt1g22920
GO:0010100 negative regulation of photomorphogenesis P
IGI
AthAt1g22920
At1g71230
GO:0010387 signalosome assembly P
IMP
AthAt1g71230
At1g22920
GO:0010388 cullin deneddylation P
IGI
SpoSPAC1687.13c
IMP
AthAt1g22920
SceS000002375
GO:0032434 regulation of proteasomal ubiquitin-dependent
protein catabolic process		 P
NAS
SpoSPAC1687.13c
GO:0032435 negative regulation of proteasomal
ubiquitin-dependent protein catabolic
process		 P
IMP
DmeFBgn0027053
GO:0040007 growth P
IMP
CelWBGene00000817
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000817
GO:0045787 positive regulation of cell cycle P
IMP
DmeFBgn0027053
GO:0045941 positive regulation of transcription P
TAS
MmuMGI:1349415
GO:0048477 oogenesis P
IMP
CelWBGene00000817
TAS
DmeFBgn0027053
GO:0050821 protein stabilization P
IMP
DmeFBgn0027053
GO:0051726 regulation of cell cycle P
IMP
MmuMGI:1349415

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1687.13c
(O94454)		 YDL216C
(S000002375)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1687.13c
GO:0005829 cytosol C
IDA
SpoSPAC1687.13c
GO:0008180 signalosome C
IDA
SceS000002375
SpoSPAC1687.13c
GO:0004222 metalloendopeptidase activity F
IMP
SceS000002375
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000002375
GO:0006914 autophagy P
RCA
SceS000002375
GO:0007049 cell cycle P
NAS
SpoSPAC1687.13c
GO:0009966 regulation of signal transduction P
RCA
SceS000002375
GO:0010388 cullin deneddylation P
IGI
SpoSPAC1687.13c
IMP
SceS000002375
GO:0032434 regulation of proteasomal ubiquitin-dependent
protein catabolic process		 P
NAS
SpoSPAC1687.13c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

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