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Search term: YDL226C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GCS1
SGD link S000002385
Alternative ID YDL226C
Description ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
Synonyms YDL226C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0704 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING ADP-ribosylation factor GTPase activator

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g37550 GI:15224315
Arabidopsis thaliana (Ath) At3g53710 GI:15231865
Caenorhabditis elegans (Cel) CE11618
(WBGene00010500)		 GI:17508013 P90904
Drosophila melanogaster (Dme) 7294580 GI:7294580
Homo sapiens (Hsa) Hs8922652
(ARFGAP1)		 GI:8922652 Q8N6T3
Saccharomyces cerevisiae (Sce) YDL226c
(S000002385)		 GI:6319975 P35197
Saccharomyces cerevisiae (Sce) YNL204c
(S000005148)		 GI:6324125 P32572
Schizosaccharomyces pombe (Spo) SPCC622.14 GI:19075686 O94601
Arabidopsis thaliana (Ath) At2g37550 GI:15224315
Arabidopsis thaliana (Ath) At3g53710 GI:15231865
Caenorhabditis elegans (Cel) CE11618
(WBGene00010500)		 GI:17508013 P90904
Drosophila melanogaster (Dme) 7294580 GI:7294580
Homo sapiens (Hsa) Hs8922652
(ARFGAP1)		 GI:8922652 Q8N6T3
Saccharomyces cerevisiae (Sce) YDL226c
(S000002385)		 GI:6319975 P35197
Saccharomyces cerevisiae (Sce) YNL204c
(S000005148)		 GI:6324125 P32572
Schizosaccharomyces pombe (Spo) SPCC622.14 GI:19075686 O94601


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
EXP
HsaARFGAP1
GO:0005575 cellular_component C
ND
SceS000005148
GO:0005634 nucleus C
IDA
AthAt2g37550
At3g53710
ISS
AthAt3g53710
At2g37550
GO:0005737 cytoplasm C
IDA
SpoSPCC622.14
GO:0005768 endosome C
IDA
SceS000002385
GO:0005793 ER-Golgi intermediate compartment C
IPI
SceS000002385
GO:0005802 trans-Golgi network C
IDA
SceS000002385
GO:0005829 cytosol C
IDA
AthAt3g53710
At2g37550
GO:0005856 cytoskeleton C
IMP
SceS000002385
IPI
SceS000002385
GO:0003674 molecular_function F
ND
SceS000005148
GO:0003677 DNA binding F
ISS
AthAt3g53710
At2g37550
GO:0003779 actin binding F
IDA
SceS000002385
GO:0005083 small GTPase regulator activity F
RCA
SceS000005148
GO:0005096 GTPase activator activity F
ISS
SpoSPCC622.14
RCA
SceS000005148
GO:0008047 enzyme activator activity F
RCA
SceS000005148
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002385
ISS
SceS000002385
RCA
SceS000005148
GO:0030234 enzyme regulator activity F
RCA
SceS000005148
GO:0030695 GTPase regulator activity F
RCA
SceS000005148
GO:0060589 nucleoside-triphosphatase regulator
activity		 F
RCA
SceS000005148
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002385
IMP
SceS000002385
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
EXP
HsaARFGAP1
IDA
SceS000002385
IGI
SceS000002385
IMP
SceS000002385
GO:0016044 cellular membrane organization P
EXP
HsaARFGAP1
GO:0016192 vesicle-mediated transport P
ISS
SpoSPCC622.14
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IGI
SceS000002385
IMP
SceS000002385
IPI
SceS000002385
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
IMP
SceS000005148
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000002385
GO:0048205 COPI coating of Golgi vesicle P
EXP
HsaARFGAP1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101560

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPCC622.14 GI:19075686 O94601
Saccharomyces cerevisiae (Sce) GCS1
(S000002385)		 GI:6319975 P35197
Kluyveromyces lactis (Kla) KLLA0D18942g GI:50307815
Eremothecium gossypii (Ego) AGOS_ABL164C GI:45185066
Magnaporthe grisea (Mgr) MGG_01745 GI:145613297
Neurospora crassa (Ncr) NCU07734.1 GI:32415924


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC622.14
GO:0005768 endosome C
IDA
SceS000002385
GO:0005793 ER-Golgi intermediate compartment C
IPI
SceS000002385
GO:0005802 trans-Golgi network C
IDA
SceS000002385
GO:0005856 cytoskeleton C
IMP
SceS000002385
IPI
SceS000002385
GO:0003779 actin binding F
IDA
SceS000002385
GO:0005096 GTPase activator activity F
ISS
SpoSPCC622.14
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002385
ISS
SceS000002385
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002385
IMP
SceS000002385
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IDA
SceS000002385
IGI
SceS000002385
IMP
SceS000002385
GO:0016192 vesicle-mediated transport P
ISS
SpoSPCC622.14
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IGI
SceS000002385
IMP
SceS000002385
IPI
SceS000002385
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000002385

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1368

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1913 ENSANGP00000004294
Anopheles gambiae (Aga) aga1914 ENSANGP00000024029
Ashbya gossypii (Ago) ago428 ABL164C
Arabidopsis thaliana (Ath) ath10842 At2g37550.1
Arabidopsis thaliana (Ath) ath16726 At3g53710.1
Caenorhabditis elegans (Cel) cel11624 K02B12.7
(CE11618;
WBGene00010500)
Candida glabrata (Cgl) cgl1858 CAGL0G05445g
Dictyostelium discoideum (Ddi) ddi5507 DDB0204568
Debaryomyces hansenii (Dha) dha1543 DEHA0C02508g
Drosophila melanogaster (Dme) dme9239 CG4237-PA
(FBgn0020655)
Danio rerio (Dre) dre12047 ENSDARP00000024796
(si:dkey-27p7.2)		 Q5RG20
Encephalitozoon cuniculi (Ecu) ecu943 19074855
Takifugu rubripes (Fru) fru23085 SINFRUP00000164775
Takifugu rubripes (Fru) fru23086 SINFRUP00000168396
Gallus gallus (Gga) gga12004 ENSGALP00000009271
Gallus gallus (Gga) gga12005 ENSGALP00000009272
(ARFGAP1)		 Q5F3T0
Homo sapiens (Hsa) hsa20615 ENSP00000217171
Homo sapiens (Hsa) hsa20616 ENSP00000314615
(ARFGAP1)		 Q8N6T3-2
Kluyveromyces lactis (Kla) kla2900 KLLA0D18942g
Mus musculus (Mmu) mmu16273 ENSMUSP00000029092
(MGI:2183559)		 Q9EPJ9-1
Mus musculus (Mmu) mmu16274 ENSMUSP00000059522
Neurospora crassa (Ncr) ncr7530 NCU07734.2
Oryza sativa (Osa) osa27268 3978.m00201
Plasmodium falciparum (Pfa) pfa5209 PFL2140c
Rattus norvegicus (Rno) rno20501 ENSRNOP00000013900
(RGD:708452)		 Q62848-1
Rattus norvegicus (Rno) rno20500 ENSRNOP00000014318
(RGD:708452)		 Q3S4A5
Rattus norvegicus (Rno) rno20502 ENSRNOP00000043193
(RGD:708452)
Rattus norvegicus (Rno) rno20499 ENSRNOP00000049775
(RGD:708452)		 Q3S4A4
Saccharomyces cerevisiae (Sce) sce1005 YDL226C
(S000002385)
Schizosaccharomyces pombe (Spo) spo151 SPCC622.14 O94601
Yarrowia lipolytica (Yli) yli1839 YALI0C02959g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
ISO
MmuMGI:2183559
GO:0005575 cellular_component C
ND
PfaPFL2140c
GO:0005634 nucleus C
IDA
AthAt2g37550
At3g53710
ISS
AthAt3g53710
At2g37550
GO:0005737 cytoplasm C
IDA
SpoSPCC622.14
GO:0005768 endosome C
IDA
SceS000002385
GO:0005793 ER-Golgi intermediate compartment C
IPI
SceS000002385
GO:0005802 trans-Golgi network C
IDA
SceS000002385
GO:0005829 cytosol C
IDA
AthAt3g53710
At2g37550
ISS
DmeFBgn0020655
GO:0005856 cytoskeleton C
IMP
SceS000002385
IPI
SceS000002385
GO:0003674 molecular_function F
ND
MmuMGI:2183559
GO:0003677 DNA binding F
ISS
AthAt3g53710
At2g37550
PfaPFL2140c
GO:0003779 actin binding F
IDA
SceS000002385
GO:0005096 GTPase activator activity F
ISS
SpoSPCC622.14
GO:0005525 GTP binding F
NAS
DmeFBgn0020655
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002385
ISS
DmeFBgn0020655
PfaPFL2140c
SceS000002385
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002385
IMP
SceS000002385
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IDA
SceS000002385
IGI
SceS000002385
IMP
SceS000002385
GO:0008150 biological_process P
ND
MmuMGI:2183559
GO:0016192 vesicle-mediated transport P
ISS
SpoSPCC622.14
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IGI
SceS000002385
IMP
SceS000002385
IPI
SceS000002385
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000002385

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC622.14
(O94601)		 YDL226C
(S000002385)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC622.14
GO:0005768 endosome C
IDA
SceS000002385
GO:0005793 ER-Golgi intermediate compartment C
IPI
SceS000002385
GO:0005802 trans-Golgi network C
IDA
SceS000002385
GO:0005856 cytoskeleton C
IMP
SceS000002385
IPI
SceS000002385
GO:0003779 actin binding F
IDA
SceS000002385
GO:0005096 GTPase activator activity F
ISS
SpoSPCC622.14
GO:0008060 ARF GTPase activator activity F
IDA
SceS000002385
ISS
SceS000002385
GO:0006888 ER to Golgi vesicle-mediated transport P
IGI
SceS000002385
IMP
SceS000002385
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IDA
SceS000002385
IGI
SceS000002385
IMP
SceS000002385
GO:0016192 vesicle-mediated transport P
ISS
SpoSPCC622.14
GO:0030037 actin filament reorganization involved in cell
cycle		 P
IGI
SceS000002385
IMP
SceS000002385
IPI
SceS000002385
GO:0043001 Golgi to plasma membrane protein
transport		 P
IMP
SceS000002385

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