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Search term: YDL238C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GUD1
SGD link S000002397
Alternative ID YDL238C
Description Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures
Synonyms YDL238C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3968 -CDHYP-

KOGs classification KOGs description
METABOLISMMETABOLISM Atrazine chlorohydrolase/guanine deaminase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE07478
(WBGene00020436)
GI:17555004 Q22419
Caenorhabditis elegans (Cel) CE26624
(WBGene00000775)
GI:17540282 Q20166
Drosophila melanogaster (Dme) 7296893 GI:7296893
Homo sapiens (Hsa) Hs22056401 GI:16549195 Q96NU7
Homo sapiens (Hsa) Hs4758426
(GDA)
GI:4758426 Q9Y2T3
Saccharomyces cerevisiae (Sce) YDL238c
(S000002397)
GI:6319963 Q07729
Schizosaccharomyces pombe (Spo) SPAC1F8.04c GI:19113705 Q92342
Schizosaccharomyces pombe (Spo) SPCC1672.03c GI:19075374 O14057


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
HsaGDA
GO:0005634 nucleus C
IDA
SpoSPAC1F8.04c
GO:0005737 cytoplasm C
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0005829 cytosol C
IDA
SpoSPCC1672.03c
SPAC1F8.04c
GO:0008892 guanine deaminase activity F
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but
not peptide) bonds, in linear amides
F
ISS
SceS000002397
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
P
TAS
HsaGDA
GO:0007399 nervous system development P
TAS
HsaGDA
GO:0019915 lipid storage P
IMP
CelWBGene00020436
GO:0033554 cellular response to stress P
IEP
SpoSPAC1F8.04c
GO:0046098 guanine metabolic process P
ISS
SceS000002397
SpoSPCC1672.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3171

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GDA GI:4758426 Q9Y2T3
Pan troglodytes (Ptr) GDA GI:114625262
Canis familiaris (Cfa) GDA GI:73946803
Mus musculus (Mmu) Gda
(MGI:95678)
GI:6753960 Q3U0C4
Rattus norvegicus (Rno) Gda
(RGD:621617)
GI:13929094
Gallus gallus (Gga) GDA GI:118104085
Drosophila melanogaster (Dme) CG18143
(FBgn0037219)
GI:24643849
Anopheles gambiae (Aga) AgaP_AGAP005282 GI:158286997
Schizosaccharomyces pombe (Spo) SPCC1672.03c GI:19075374 O14057
Saccharomyces cerevisiae (Sce) GUD1
(S000002397)
GI:6319963 Q07729
Kluyveromyces lactis (Kla) KLLA0D19492g GI:50307867
Magnaporthe grisea (Mgr) MGG_04119 GI:39944216
Neurospora crassa (Ncr) NCU07309.1 GI:32414231


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
TAS
HsaGDA
GO:0005737 cytoplasm C
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0005829 cytosol C
IDA
SpoSPCC1672.03c
GO:0005515 protein binding F
IPI
MmuMGI:95678
GO:0008892 guanine deaminase activity F
IDA
SceS000002397
ISO
MmuMGI:95678
ISS
SpoSPCC1672.03c
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but
not peptide) bonds, in linear amides
F
ISS
SceS000002397
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process
P
TAS
HsaGDA
GO:0007399 nervous system development P
TAS
HsaGDA
GO:0046098 guanine metabolic process P
ISS
SceS000002397
SpoSPCC1672.03c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1184

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga682 ENSANGP00000019574
Caenorhabditis elegans (Cel) cel8525 F38E11.3
(CE26624;
WBGene00000775)
Candida glabrata (Cgl) cgl656 CAGL0C05555g
Cryptococcus neoformans (Cne) cne2737 183.m01671
Dictyostelium discoideum (Ddi) ddi8683 DDB0186514
Dictyostelium discoideum (Ddi) ddi12786 DDB0230211
Debaryomyces hansenii (Dha) dha236 DEHA0A05324g
Drosophila melanogaster (Dme) dme10809 CG18143-PA
(FBgn0037219)
Danio rerio (Dre) dre19124 ENSDARP00000010155
(zgc:112282)
Q502E8
Danio rerio (Dre) dre19126 ENSDARP00000039669
Escherichia coli (Eco) eco2786 16130785
Takifugu rubripes (Fru) fru27744 SINFRUP00000136555
Gallus gallus (Gga) gga27806 ENSGALP00000024386
(GDA)
Homo sapiens (Hsa) hsa31407 ENSP00000238018
(GDA)
Q9H335
Homo sapiens (Hsa) hsa31406 ENSP00000351170
(GDA)
Q9Y2T3
Kluyveromyces lactis (Kla) kla2926 KLLA0D19492g
Mus musculus (Mmu) mmu13500 ENSMUSP00000074937
Neurospora crassa (Ncr) ncr7115 NCU07309.2
Neurospora crassa (Ncr) ncr9366 NCU09621.2
Oryza sativa (Osa) osa70063 7095.m00120
Oryza sativa (Osa) osa73575 7122.m00117
Rattus norvegicus (Rno) rno3882 ENSRNOP00000024775
(RGD:621617)
Q9JKB7
Rattus norvegicus (Rno) rno3881 ENSRNOP00000042887
Saccharomyces cerevisiae (Sce) sce1017 YDL238C
(S000002397)
Schizosaccharomyces pombe (Spo) spo1501 SPAC1F8.04c Q92342
Schizosaccharomyces pombe (Spo) spo2186 SPCC1672.03c O14057
Yarrowia lipolytica (Yli) yli4918 YALI0E25740g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1F8.04c
GO:0005737 cytoplasm C
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0005829 cytosol C
IDA
SpoSPCC1672.03c
SPAC1F8.04c
GO:0008892 guanine deaminase activity F
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but
not peptide) bonds, in linear amides
F
ISS
SceS000002397
GO:0033554 cellular response to stress P
IEP
SpoSPAC1F8.04c
GO:0046098 guanine metabolic process P
ISS
SceS000002397
SpoSPCC1672.03c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC1672.03c
(O14057)
YDL238C
(S000002397)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0005829 cytosol C
IDA
SpoSPCC1672.03c
GO:0008892 guanine deaminase activity F
IDA
SceS000002397
ISS
SpoSPCC1672.03c
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but
not peptide) bonds, in linear amides
F
ISS
SceS000002397
GO:0046098 guanine metabolic process P
ISS
SceS000002397
SpoSPCC1672.03c

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GO info in one table:

s.khadayate@ucl.ac.uk