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Search term: YDL246C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SOR2
SGD link S000002405
Alternative ID YDL246C
Description Protein of unknown function; protein sequence is 99% identical to the Sor1p sorbitol dehydrogenase; computational analysis of large-scale protein-protein interaction data also suggests a role in fructose or mannose metabolism
Synonyms YDL246C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0024 ACDHYP-

KOGs classification KOGs description
METABOLISM Sorbitol dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g51970 GI:15242240
Caenorhabditis elegans (Cel) CE06215
(WBGene00011003)		 GI:17562876 Q21702
Caenorhabditis elegans (Cel) CE06216
(WBGene00011004)		 GI:17562878 Q21703
Drosophila melanogaster (Dme) 7298873
(FBgn0024289)		 GI:17137530
Drosophila melanogaster (Dme) 7299382
(FBgn0022359)		 GI:17737897
Drosophila melanogaster (Dme) 7300579 GI:7300579
Homo sapiens (Hsa) Hs18583841 GI:18583841
Homo sapiens (Hsa) Hs20549232 GI:20549232
Homo sapiens (Hsa) Hs4507155 GI:4507155
Saccharomyces cerevisiae (Sce) YAL060w
(S000000056)		 GI:6319258 P39714
Saccharomyces cerevisiae (Sce) YAL061w
(S000000057)		 GI:6319257 P39713
Saccharomyces cerevisiae (Sce) YDL246c
(S000002405)		 GI:6319955 Q07786
Saccharomyces cerevisiae (Sce) YJR159w
(S000003920)		 GI:6322619 P35497
Saccharomyces cerevisiae (Sce) YLR070c
(S000004060)		 GI:6323099 Q07993
Schizosaccharomyces pombe (Spo) SPBC1198.01 GI:19111862 Q9P6I8
Schizosaccharomyces pombe (Spo) SPBC1773.05c GI:19111912 P36624
Arabidopsis thaliana (Ath) At5g51970 GI:15242240
Caenorhabditis elegans (Cel) CE06215
(WBGene00011003)		 GI:17562876 Q21702
Caenorhabditis elegans (Cel) CE06216
(WBGene00011004)		 GI:17562878 Q21703
Drosophila melanogaster (Dme) 7298873
(FBgn0024289)		 GI:17137530
Drosophila melanogaster (Dme) 7299382
(FBgn0022359)		 GI:17737897
Drosophila melanogaster (Dme) 7300579 GI:7300579
Homo sapiens (Hsa) Hs18583841 GI:18583841
Homo sapiens (Hsa) Hs20549232 GI:20549232
Homo sapiens (Hsa) Hs4507155 GI:4507155
Saccharomyces cerevisiae (Sce) YAL060w
(S000000056)		 GI:6319258 P39714
Saccharomyces cerevisiae (Sce) YAL061w
(S000000057)		 GI:6319257 P39713
Saccharomyces cerevisiae (Sce) YDL246c
(S000002405)		 GI:6319955 Q07786
Saccharomyces cerevisiae (Sce) YJR159w
(S000003920)		 GI:6322619 P35497
Saccharomyces cerevisiae (Sce) YLR070c
(S000004060)		 GI:6323099 Q07993
Schizosaccharomyces pombe (Spo) SPBC1198.01 GI:19111862 Q9P6I8
Schizosaccharomyces pombe (Spo) SPBC1773.05c GI:19111912 P36624
Arabidopsis thaliana (Ath) At5g51970 GI:15242240
Caenorhabditis elegans (Cel) CE06215
(WBGene00011003)		 GI:17562876 Q21702
Caenorhabditis elegans (Cel) CE06216
(WBGene00011004)		 GI:17562878 Q21703
Drosophila melanogaster (Dme) 7298873
(FBgn0024289)		 GI:17137530
Drosophila melanogaster (Dme) 7299382
(FBgn0022359)		 GI:17737897
Drosophila melanogaster (Dme) 7300579 GI:7300579
Homo sapiens (Hsa) Hs18583841 GI:18583841
Homo sapiens (Hsa) Hs20549232 GI:20549232
Homo sapiens (Hsa) Hs4507155 GI:4507155
Saccharomyces cerevisiae (Sce) YAL060w
(S000000056)		 GI:6319258 P39714
Saccharomyces cerevisiae (Sce) YAL061w
(S000000057)		 GI:6319257 P39713
Saccharomyces cerevisiae (Sce) YDL246c
(S000002405)		 GI:6319955 Q07786
Saccharomyces cerevisiae (Sce) YJR159w
(S000003920)		 GI:6322619 P35497
Saccharomyces cerevisiae (Sce) YLR070c
(S000004060)		 GI:6323099 Q07993
Schizosaccharomyces pombe (Spo) SPBC1198.01 GI:19111862 Q9P6I8
Schizosaccharomyces pombe (Spo) SPBC1773.05c GI:19111912 P36624


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003920
S000002405
S000004060
GO:0005634 nucleus C
IDA
SceS000000057
GO:0005737 cytoplasm C
IDA
SceS000000057
S000000056
GO:0005794 Golgi apparatus C
IDA
SpoSPBC1198.01
GO:0005829 cytosol C
IDA
SpoSPBC1773.05c
GO:0000721 (R,R)-butanediol dehydrogenase
activity		 F
IDA
SceS000000056
GO:0003939 L-iditol 2-dehydrogenase activity F
IDA
SceS000003920
ISS
DmeFBgn0022359
SceS000003920
S000002405
SpoSPBC1773.05c
NAS
DmeFBgn0024289
TAS
DmeFBgn0022359
GO:0016616 oxidoreductase activity, acting on the CH-OH group
of donors, NAD or NADP as acceptor		 F
ISS
SceS000000057
GO:0046526 D-xylulose reductase activity F
IDA
SceS000004060
ISS
SpoSPBC1773.05c
GO:0005999 xylulose biosynthetic process P
IDA
SceS000004060
IEP
SceS000004060
GO:0006066 alcohol metabolic process P
IMP
SceS000000056
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000057
GO:0008150 biological_process P
ND
SceS000000057
SpoSPBC1198.01
GO:0009266 response to temperature stimulus P
RCA
SceS000000057
GO:0009636 response to toxin P
RCA
SceS000003920
GO:0019318 hexose metabolic process P
IEP
SceS000003920
ISS
SceS000002405
GO:0019407 hexitol catabolic process P
IC
SpoSPBC1773.05c
GO:0033554 cellular response to stress P
IEP
SpoSPBC1773.05c
GO:0034079 butanediol biosynthetic process P
IMP
SceS000000056
GO:0051098 regulation of binding P
RCA
SceS000003920
S000002405

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56080

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SORD GI:156627571
Pan troglodytes (Ptr) SORD GI:114656772
Canis familiaris (Cfa) SORD GI:74000494
Mus musculus (Mmu) Sord
(MGI:98266)		 GI:22128627 Q64442
Rattus norvegicus (Rno) Sord
(RGD:3734)		 GI:77404286 34444
Gallus gallus (Gga) SORD GI:50752703
Drosophila melanogaster (Dme) Sodh-1
(FBgn0024289)		 GI:17137530
Drosophila melanogaster (Dme) Sodh-2
(FBgn0022359)		 GI:17737897
Anopheles gambiae (Aga) AgaP_AGAP003584 GI:158291803
Caenorhabditis elegans (Cel) R04B5.6
(CE06216;
WBGene00011004)		 GI:17562878 Q21703
Caenorhabditis elegans (Cel) R04B5.5
(CE06215;
WBGene00011003)		 GI:17562876 Q21702
Schizosaccharomyces pombe (Spo) tms1
(SPBC1773.05c)		 GI:19111912 P36624
Saccharomyces cerevisiae (Sce) SOR2
(S000002405)		 GI:6319955 Q07786
Saccharomyces cerevisiae (Sce) SOR1
(S000003920)		 GI:6322619 P35497
Kluyveromyces lactis (Kla) KLLA0D05511g GI:50306665
Eremothecium gossypii (Ego) AGOS_ABR229C GI:45185461
Magnaporthe grisea (Mgr) MGG_01176 GI:145614058
Neurospora crassa (Ncr) NCU00891.1 GI:32409181
Arabidopsis thaliana (Ath) AT5G51970 GI:15242240
Oryza sativa (Osa) Os08g0545200 GI:115477633


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003920
S000002405
GO:0005615 extracellular space C
TAS
HsaSORD
GO:0005624 membrane fraction C
IDA
HsaSORD
GO:0005625 soluble fraction C
IDA
HsaSORD
MmuMGI:98266
ISS
HsaSORD
GO:0005829 cytosol C
IDA
SpoSPBC1773.05c
GO:0003939 L-iditol 2-dehydrogenase activity F
IDA
HsaSORD
MmuMGI:98266
SceS000003920
ISS
DmeFBgn0022359
HsaSORD
SceS000003920
S000002405
SpoSPBC1773.05c
NAS
DmeFBgn0024289
TAS
DmeFBgn0022359
GO:0005529 sugar binding F
NAS
HsaSORD
GO:0008270 zinc ion binding F
IDA
HsaSORD
ISO
MmuMGI:98266
ISS
HsaSORD
GO:0042802 identical protein binding F
ISO
MmuMGI:98266
GO:0046526 D-xylulose reductase activity F
ISS
SpoSPBC1773.05c
GO:0051287 NAD or NADH binding F
IDA
HsaSORD
GO:0006006 glucose metabolic process P
TAS
HsaSORD
GO:0006060 sorbitol metabolic process P
IDA
MmuMGI:98266
GO:0006062 sorbitol catabolic process P
IDA
HsaSORD
GO:0009636 response to toxin P
RCA
SceS000003920
GO:0009725 response to hormone stimulus P
ISO
MmuMGI:98266
GO:0019318 hexose metabolic process P
IEP
SceS000003920
ISS
SceS000002405
GO:0019407 hexitol catabolic process P
IC
SpoSPBC1773.05c
GO:0030317 sperm motility P
NAS
HsaSORD
GO:0033554 cellular response to stress P
IEP
SpoSPBC1773.05c
GO:0046370 fructose biosynthetic process P
IDA
HsaSORD
GO:0046686 response to cadmium ion P
ISO
MmuMGI:98266
GO:0046688 response to copper ion P
ISO
MmuMGI:98266
GO:0051098 regulation of binding P
RCA
SceS000003920
S000002405
GO:0051160 L-xylitol catabolic process P
IDA
HsaSORD
GO:0051164 L-xylitol metabolic process P
IDA
HsaSORD

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_355

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6028 ENSANGP00000011284
Anopheles gambiae (Aga) aga6029 ENSANGP00000011286
Anopheles gambiae (Aga) aga6031 ENSANGP00000011358
Ashbya gossypii (Ago) ago823 ABR229C
Arabidopsis thaliana (Ath) ath27144 At5g51970.1
Arabidopsis thaliana (Ath) ath27145 At5g51970.2
Caenorhabditis elegans (Cel) cel13286 R04B5.5
(CE06215;
WBGene00011003)
Caenorhabditis elegans (Cel) cel13287 R04B5.6
(CE06216;
WBGene00011004)
Candida glabrata (Cgl) cgl667 CAGL0D00198g
Cryptococcus neoformans (Cne) cne3682 176.m02422
Cryptococcus neoformans (Cne) cne4105 177.m02864
Cryptococcus neoformans (Cne) cne5677 179.m00539
Cryptococcus neoformans (Cne) cne5709 179.m00574
Cryptococcus neoformans (Cne) cne2036 181.m08019
Cryptococcus neoformans (Cne) cne1914 181.m08701
Debaryomyces hansenii (Dha) dha645 DEHA0A14410g
Debaryomyces hansenii (Dha) dha704 DEHA0B00583g
Debaryomyces hansenii (Dha) dha1242 DEHA0B12980g
Debaryomyces hansenii (Dha) dha5206 DEHA0F18337g
Debaryomyces hansenii (Dha) dha5207 DEHA0F18359g
Drosophila melanogaster (Dme) dme11299 CG1982-PA
(FBgn0024289)
Drosophila melanogaster (Dme) dme11968 CG4649-PA
(FBgn0022359)
Danio rerio (Dre) dre21446 ENSDARP00000041702
Danio rerio (Dre) dre31673 ENSDARP00000042422
Danio rerio (Dre) dre31672 ENSDARP00000043943
Escherichia coli (Eco) eco1730 16129728
Escherichia coli (Eco) eco2466 16130470
Escherichia coli (Eco) eco3496 16131487
Takifugu rubripes (Fru) fru22149 SINFRUP00000144094
Gallus gallus (Gga) gga3646 ENSGALP00000003636
Gallus gallus (Gga) gga3645 ENSGALP00000003637
(SORD)
Gallus gallus (Gga) gga3644 ENSGALP00000003641
Homo sapiens (Hsa) hsa10588 ENSP00000267814
(SORD)		 Q00796
Kluyveromyces lactis (Kla) kla2305 KLLA0D05511g
Kluyveromyces lactis (Kla) kla4101 KLLA0F00506g
Kluyveromyces lactis (Kla) kla4102 KLLA0F00528g
Mus musculus (Mmu) mmu15382 ENSMUSP00000028657
(MGI:98266)
Neurospora crassa (Ncr) ncr624 NCU00643.2
Neurospora crassa (Ncr) ncr867 NCU00891.2
Oryza sativa (Osa) osa25993 3908.m00133
Oryza sativa (Osa) osa26031 3908.m00180
Oryza sativa (Osa) osa74524 7300.m00081
Rattus norvegicus (Rno) rno19584 ENSRNOP00000023350
(RGD:3734)		 P27867
Saccharomyces cerevisiae (Sce) sce71 YAL061W
(S000000057)
Saccharomyces cerevisiae (Sce) sce1026 YDL246C
(S000002405)
Saccharomyces cerevisiae (Sce) sce3658 YJR159W
(S000003920)
Saccharomyces cerevisiae (Sce) sce4151 YLR070C
(S000004060)
Schizosaccharomyces pombe (Spo) spo3675 SPBC1773.05c P36624
Yarrowia lipolytica (Yli) yli4380 YALI0E12463g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000003920
S000002405
S000004060
GO:0005625 soluble fraction C
IDA
MmuMGI:98266
GO:0005634 nucleus C
IDA
SceS000000057
GO:0005737 cytoplasm C
IDA
SceS000000057
GO:0005829 cytosol C
IDA
SpoSPBC1773.05c
GO:0003939 L-iditol 2-dehydrogenase activity F
IDA
MmuMGI:98266
SceS000003920
ISS
DmeFBgn0022359
SceS000003920
S000002405
SpoSPBC1773.05c
NAS
DmeFBgn0024289
TAS
DmeFBgn0022359
GO:0008270 zinc ion binding F
ISO
MmuMGI:98266
GO:0016616 oxidoreductase activity, acting on the CH-OH group
of donors, NAD or NADP as acceptor		 F
ISS
SceS000000057
GO:0042802 identical protein binding F
ISO
MmuMGI:98266
GO:0046526 D-xylulose reductase activity F
IDA
SceS000004060
ISS
SpoSPBC1773.05c
GO:0005999 xylulose biosynthetic process P
IDA
SceS000004060
IEP
SceS000004060
GO:0006060 sorbitol metabolic process P
IDA
MmuMGI:98266
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000000057
GO:0008150 biological_process P
ND
SceS000000057
GO:0009266 response to temperature stimulus P
RCA
SceS000000057
GO:0009636 response to toxin P
RCA
SceS000003920
GO:0009725 response to hormone stimulus P
ISO
MmuMGI:98266
GO:0019318 hexose metabolic process P
IEP
SceS000003920
ISS
SceS000002405
GO:0019407 hexitol catabolic process