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Search term: YDR001C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NTH1
SGD link S000002408
Alternative ID YDR001C
Description Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p
Synonyms YDR001C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0602 ACDHYPE

KOGs classification KOGs description
METABOLISM Neutral trehalase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g24040 GI:15233663
Caenorhabditis elegans (Cel) CE04897
(WBGene00006608)		 GI:17542196 Q9GYK9
Caenorhabditis elegans (Cel) CE05631 GI:17567007
Caenorhabditis elegans (Cel) CE06551
(WBGene00006609)		 GI:17565078 Q23176
Caenorhabditis elegans (Cel) CE11310 GI:17507749
Caenorhabditis elegans (Cel) CE19363 GI:17532027
Drosophila melanogaster (Dme) 7291236 GI:7291236 A4UZR3
Drosophila melanogaster (Dme) 7302932 GI:20130053
Drosophila melanogaster (Dme) 7302933 GI:7302933
Homo sapiens (Hsa) Hs22064895 GI:22064895
Homo sapiens (Hsa) Hs6005914 GI:6005914
Saccharomyces cerevisiae (Sce) YBR001c
(S000000205)		 GI:6319473 P35172
Saccharomyces cerevisiae (Sce) YDR001c
(S000002408)		 GI:6320204 P32356
Schizosaccharomyces pombe (Spo) SPBC660.07 GI:19111878 O42893
Encephalitozoon cuniculi (Ecu) ECU02g1370 GI:19074056 Q8SQJ2
Arabidopsis thaliana (Ath) At4g24040 GI:15233663
Caenorhabditis elegans (Cel) CE04897
(WBGene00006608)		 GI:17542196 Q9GYK9
Caenorhabditis elegans (Cel) CE05631 GI:17567007
Caenorhabditis elegans (Cel) CE06551
(WBGene00006609)		 GI:17565078 Q23176
Caenorhabditis elegans (Cel) CE11310 GI:17507749
Caenorhabditis elegans (Cel) CE19363 GI:17532027
Drosophila melanogaster (Dme) 7291236 GI:7291236 A4UZR3
Drosophila melanogaster (Dme) 7302932 GI:20130053
Drosophila melanogaster (Dme) 7302933 GI:7302933
Homo sapiens (Hsa) Hs22064895 GI:22064895
Homo sapiens (Hsa) Hs6005914 GI:6005914
Saccharomyces cerevisiae (Sce) YBR001c
(S000000205)		 GI:6319473 P35172
Saccharomyces cerevisiae (Sce) YDR001c
(S000002408)		 GI:6320204 P32356
Schizosaccharomyces pombe (Spo) SPBC660.07 GI:19111878 O42893
Encephalitozoon cuniculi (Ecu) ECU02g1370 GI:19074056 Q8SQJ2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002408
S000000205
GO:0005739 mitochondrion C
IDA
SceS000000205
GO:0005829 cytosol C
IDA
SpoSPBC660.07
TAS
SceS000002408
GO:0004555 alpha,alpha-trehalase activity F
IDA
AthAt4g24040
IMP
SceS000000205
TAS
SceS000002408
SpoSPBC660.07
GO:0005509 calcium ion binding F
IDA
SpoSPBC660.07
GO:0005515 protein binding F
IPI
SpoSPBC660.07
GO:0015927 trehalase activity F
ISS
AthAt4g24040
GO:0005991 trehalose metabolic process P
TAS
SpoSPBC660.07
GO:0005993 trehalose catabolic process P
IDA
AthAt4g24040
IMP
SceS000000205
TAS
SceS000002408
GO:0006112 energy reserve metabolic process P
RCA
SceS000002408
GO:0006950 response to stress P
TAS
SceS000002408
GO:0006970 response to osmotic stress P
IDA
SpoSPBC660.07
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002408
GO:0009266 response to temperature stimulus P
RCA
SceS000002408
GO:0009409 response to cold P
IDA
SpoSPBC660.07
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002408
GO:0030437 ascospore formation P
IMP
SpoSPBC660.07
GO:0034599 cellular response to oxidative
stress		 P
IDA
SpoSPBC660.07
GO:0034605 cellular response to heat P
IDA
SpoSPBC660.07
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000002408

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5351

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) ntp1
(SPBC660.07)		 GI:19111878 O42893
Saccharomyces cerevisiae (Sce) NTH2
(S000000205)		 GI:6319473 P35172
Saccharomyces cerevisiae (Sce) NTH1
(S000002408)		 GI:6320204 P32356
Kluyveromyces lactis (Kla) TREA_KLULA GI:50309441
Eremothecium gossypii (Ego) AGOS_AER001C GI:45190607
Magnaporthe grisea (Mgr) MGG_09471 GI:39960831
Neurospora crassa (Ncr) NCU04221.1 GI:32405896


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002408
S000000205
GO:0005739 mitochondrion C
IDA
SceS000000205
GO:0005829 cytosol C
IDA
SpoSPBC660.07
TAS
SceS000002408
GO:0004555 alpha,alpha-trehalase activity F
IMP
SceS000000205
TAS
SceS000002408
SpoSPBC660.07
GO:0005509 calcium ion binding F
IDA
SpoSPBC660.07
GO:0005515 protein binding F
IPI
SpoSPBC660.07
GO:0005991 trehalose metabolic process P
TAS
SpoSPBC660.07
GO:0005993 trehalose catabolic process P
IMP
SceS000000205
TAS
SceS000002408
GO:0006112 energy reserve metabolic process P
RCA
SceS000002408
GO:0006950 response to stress P
TAS
SceS000002408
GO:0006970 response to osmotic stress P
IDA
SpoSPBC660.07
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002408
GO:0009266 response to temperature stimulus P
RCA
SceS000002408
GO:0009409 response to cold P
IDA
SpoSPBC660.07
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002408
GO:0030437 ascospore formation P
IMP
SpoSPBC660.07
GO:0034599 cellular response to oxidative
stress		 P
IDA
SpoSPBC660.07
GO:0034605 cellular response to heat P
IDA
SpoSPBC660.07
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000002408

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1380

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9235 ENSANGP00000008628
Anopheles gambiae (Aga) aga13108 ENSANGP00000015519
Ashbya gossypii (Ago) ago2506 AER001C
Arabidopsis thaliana (Ath) ath20360 At4g24040.1
Caenorhabditis elegans (Cel) cel10716 F57B10.7
(CE30545;
WBGene00006607)
Caenorhabditis elegans (Cel) cel14557 T05A12.2
(CE04897;
WBGene00006608)
Caenorhabditis elegans (Cel) cel17060 W05E10.4
(CE06551;
WBGene00006609)
Candida glabrata (Cgl) cgl604 CAGL0C04323g
Candida glabrata (Cgl) cgl5113 CAGL0M10439g
Cryptococcus neoformans (Cne) cne4163 177.m02922
Cryptococcus neoformans (Cne) cne4828 186.m03704
Dictyostelium discoideum (Ddi) ddi6365 DDB0185541
Debaryomyces hansenii (Dha) dha799 DEHA0B02673g
Drosophila melanogaster (Dme) dme6269 CG9364-PA
(FBgn0003748)
Drosophila melanogaster (Dme) dme6270 CG9364-PB
(FBgn0003748)
Drosophila melanogaster (Dme) dme6271 CG9364-PC
(FBgn0003748)
Drosophila melanogaster (Dme) dme6268 CG9364-PD
(FBgn0003748)
Drosophila melanogaster (Dme) dme6267 CG9364-PE
(FBgn0003748)
Drosophila melanogaster (Dme) dme6272 CG9364-PF
(FBgn0003748)
Danio rerio (Dre) dre24573 ENSDARP00000023690
Danio rerio (Dre) dre24574 ENSDARP00000028679
Escherichia coli (Eco) eco1159 16129160
Escherichia coli (Eco) eco3398 16131391
Encephalitozoon cuniculi (Ecu) ecu135 19074056
Takifugu rubripes (Fru) fru8067 SINFRUP00000156726
Takifugu rubripes (Fru) fru8066 SINFRUP00000156728
Homo sapiens (Hsa) hsa6650 ENSP00000264029
(TREH)		 O43280-1
Kluyveromyces lactis (Kla) kla3727 KLLA0E17325g
Mus musculus (Mmu) mmu27499 ENSMUSP00000034609
(MGI:1926230)		 Q9JLT2
Neurospora crassa (Ncr) ncr917 NCU00943.2
Neurospora crassa (Ncr) ncr4097 NCU04221.2
Oryza sativa (Osa) osa315 37.m00088
Oryza sativa (Osa) osa332 37.m00177
Rattus norvegicus (Rno) rno28466 ENSRNOP00000018054
(RGD:61831)		 O70282
Saccharomyces cerevisiae (Sce) sce252 YBR001C
(S000000205)
Saccharomyces cerevisiae (Sce) sce1030 YDR001C
(S000002408)
Schizosaccharomyces pombe (Spo) spo4649 SPBC660.07 O42893
Yarrowia lipolytica (Yli) yli3352 YALI0D15598g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002408
S000000205
GO:0005739 mitochondrion C
IDA
SceS000000205
GO:0005829 cytosol C
IDA
SpoSPBC660.07
TAS
SceS000002408
GO:0005903 brush border C
TAS
MmuMGI:1926230
GO:0046658 anchored to plasma membrane C
ISS
DmeFBgn0003748
GO:0004555 alpha,alpha-trehalase activity F
IDA
AthAt4g24040
IMP
SceS000000205
ISS
DmeFBgn0003748
TAS
DmeFBgn0003748
SceS000002408
SpoSPBC660.07
GO:0005509 calcium ion binding F
IDA
SpoSPBC660.07
GO:0005515 protein binding F
IPI
SpoSPBC660.07
GO:0015927 trehalase activity F
IMP
DmeFBgn0003748
ISS
AthAt4g24040
GO:0005991 trehalose metabolic process P
ISS
DmeFBgn0003748
TAS
SpoSPBC660.07
GO:0005993 trehalose catabolic process P
IDA
AthAt4g24040
IMP
SceS000000205
TAS
SceS000002408
GO:0006112 energy reserve metabolic process P
RCA
SceS000002408
GO:0006950 response to stress P
TAS
SceS000002408
GO:0006970 response to osmotic stress P
IDA
SpoSPBC660.07
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002408
GO:0009266 response to temperature stimulus P
RCA
SceS000002408
GO:0009409 response to cold P
IDA
SpoSPBC660.07
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006607
GO:0009887 organ morphogenesis P
ISO
MmuMGI:1926230
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002408
GO:0030437 ascospore formation P
IMP
SpoSPBC660.07
GO:0034599 cellular response to oxidative
stress		 P
IDA
SpoSPBC660.07
GO:0034605 cellular response to heat P
IDA
SpoSPBC660.07
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000002408

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC660.07
(O42893)		 YDR001C
(S000002408)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002408
GO:0005829 cytosol C
IDA
SpoSPBC660.07
TAS
SceS000002408
GO:0004555 alpha,alpha-trehalase activity F
TAS
SceS000002408
SpoSPBC660.07
GO:0005509 calcium ion binding F
IDA
SpoSPBC660.07
GO:0005515 protein binding F
IPI
SpoSPBC660.07
GO:0005991 trehalose metabolic process P
TAS
SpoSPBC660.07
GO:0005993 trehalose catabolic process P
TAS
SceS000002408
GO:0006112 energy reserve metabolic process P
RCA
SceS000002408
GO:0006950 response to stress P
TAS
SceS000002408
GO:0006970 response to osmotic stress P
IDA
SpoSPBC660.07
GO:0007039 vacuolar protein catabolic process P
RCA
SceS000002408
GO:0009266 response to temperature stimulus P
RCA
SceS000002408
GO:0009409 response to cold P
IDA
SpoSPBC660.07
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002408
GO:0030437 ascospore formation P
IMP
SpoSPBC660.07
GO:0034599 cellular response to oxidative
stress		 P
IDA
SpoSPBC660.07
GO:0034605 cellular response to heat P
IDA
SpoSPBC660.07
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000002408

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