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Search term: YDR040C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ENA1
SGD link S000002447
Alternative ID YDR040C
Description P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
Synonyms YDR040C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0202 ACDHYP-

KOGs classification KOGs description
METABOLISM Ca2+ transporting ATPase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g07670 GI:15222475
Arabidopsis thaliana (Ath) At1g07810 GI:15223017
Arabidopsis thaliana (Ath) At1g10130 GI:15218415
Arabidopsis thaliana (Ath) At4g00900 GI:15236991
Caenorhabditis elegans (Cel) CE18884
(WBGene00004736)		 GI:17554158 Q9XTG6
Caenorhabditis elegans (Cel) CE18885 GI:17554156
Caenorhabditis elegans (Cel) CE20426 GI:17511047
Caenorhabditis elegans (Cel) CE27556
(WBGene00004063)		 GI:17511049
Drosophila melanogaster (Dme) 7291680 GI:12644163
Drosophila melanogaster (Dme) 7296577 GI:7296577 Q9VNR2
Homo sapiens (Hsa) Hs4885077 GI:4885077
Homo sapiens (Hsa) Hs7656910 GI:7656910
Homo sapiens (Hsa) Hs7662256 GI:7662256
Homo sapiens (Hsa) Hs10835220 GI:10835220 O14983
Homo sapiens (Hsa) Hs4502285 GI:4502285 P16615
Saccharomyces cerevisiae (Sce) YDR038c
(S000002445)		 GI:6320243 Q12691
Saccharomyces cerevisiae (Sce) YDR039c
(S000002446)		 GI:6320244 Q01896
Saccharomyces cerevisiae (Sce) YDR040c
(S000002447)		 GI:6320245 P13587
Saccharomyces cerevisiae (Sce) YGL167c
(S000003135)		 GI:6321271 P13586
Schizosaccharomyces pombe (Spo) SPBC31E1.02c GI:19111890 O59868
Schizosaccharomyces pombe (Spo) SPBC839.06 GI:19112038 P22189
Arabidopsis thaliana (Ath) At1g07670 GI:15222475
Arabidopsis thaliana (Ath) At1g07810 GI:15223017
Arabidopsis thaliana (Ath) At1g10130 GI:15218415
Arabidopsis thaliana (Ath) At4g00900 GI:15236991
Caenorhabditis elegans (Cel) CE18884
(WBGene00004736)		 GI:17554158 Q9XTG6
Caenorhabditis elegans (Cel) CE18885 GI:17554156
Caenorhabditis elegans (Cel) CE20426 GI:17511047
Caenorhabditis elegans (Cel) CE27556
(WBGene00004063)		 GI:17511049
Drosophila melanogaster (Dme) 7291680 GI:12644163
Drosophila melanogaster (Dme) 7296577 GI:7296577 Q9VNR2
Homo sapiens (Hsa) Hs4885077 GI:4885077
Homo sapiens (Hsa) Hs7656910 GI:7656910
Homo sapiens (Hsa) Hs7662256 GI:7662256
Homo sapiens (Hsa) Hs10835220 GI:10835220 O14983
Homo sapiens (Hsa) Hs4502285 GI:4502285 P16615
Saccharomyces cerevisiae (Sce) YDR038c
(S000002445)		 GI:6320243 Q12691
Saccharomyces cerevisiae (Sce) YDR039c
(S000002446)		 GI:6320244 Q01896
Saccharomyces cerevisiae (Sce) YDR040c
(S000002447)		 GI:6320245 P13587
Saccharomyces cerevisiae (Sce) YGL167c
(S000003135)		 GI:6321271 P13586
Schizosaccharomyces pombe (Spo) SPBC31E1.02c GI:19111890 O59868
Schizosaccharomyces pombe (Spo) SPBC839.06 GI:19112038 P22189
Arabidopsis thaliana (Ath) At1g07670 GI:15222475
Arabidopsis thaliana (Ath) At1g07810 GI:15223017
Arabidopsis thaliana (Ath) At1g10130 GI:15218415
Arabidopsis thaliana (Ath) At4g00900 GI:15236991
Caenorhabditis elegans (Cel) CE18884
(WBGene00004736)		 GI:17554158 Q9XTG6
Caenorhabditis elegans (Cel) CE18885 GI:17554156
Caenorhabditis elegans (Cel) CE20426 GI:17511047
Caenorhabditis elegans (Cel) CE27556
(WBGene00004063)		 GI:17511049
Drosophila melanogaster (Dme) 7291680 GI:12644163
Drosophila melanogaster (Dme) 7296577 GI:7296577 Q9VNR2
Homo sapiens (Hsa) Hs4885077 GI:4885077
Homo sapiens (Hsa) Hs7656910 GI:7656910
Homo sapiens (Hsa) Hs7662256 GI:7662256
Homo sapiens (Hsa) Hs10835220 GI:10835220 O14983
Homo sapiens (Hsa) Hs4502285 GI:4502285 P16615
Saccharomyces cerevisiae (Sce) YDR038c
(S000002445)		 GI:6320243 Q12691
Saccharomyces cerevisiae (Sce) YDR039c
(S000002446)		 GI:6320244 Q01896
Saccharomyces cerevisiae (Sce) YDR040c
(S000002447)		 GI:6320245 P13587
Saccharomyces cerevisiae (Sce) YGL167c
(S000003135)		 GI:6321271 P13586
Schizosaccharomyces pombe (Spo) SPBC31E1.02c GI:19111890 O59868
Schizosaccharomyces pombe (Spo) SPBC839.06 GI:19112038 P22189


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000003135
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002445
S000002447
GO:0005624 membrane fraction C
IDA
CelWBGene00004063
SceS000002445
S000002446
S000002447
GO:0005739 mitochondrion C
IDA
SceS000002446
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g07810
At1g07670
CelWBGene00004736
SpoSPBC31E1.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
AthAt1g07810
GO:0005794 Golgi apparatus C
IDA
AthAt1g10130
CelWBGene00004063
GO:0005886 plasma membrane C
IDA
AthAt1g07810
At1g07670
SceS000002446
S000002447
ISS
SceS000002445
GO:0012505 endomembrane system C
IDA
AthAt1g10130
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IC
SpoSPBC31E1.02c
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
CelWBGene00004736
GO:0005388 calcium-transporting ATPase activity F
IDA
AthAt1g07810
CelWBGene00004063
SceS000003135
IGI
AthAt1g07810
IMP
AthAt1g10130
SceS000003135
ISS
AthAt1g10130
At4g00900
At1g07810
At1g07670
SceS000003135
SpoSPBC31E1.02c
TAS
SpoSPBC839.06
GO:0005509 calcium ion binding F
IDA
SceS000003135
ISS
SpoSPBC31E1.02c
GO:0005516 calmodulin binding F
ISS
AthAt1g10130
GO:0005524 ATP binding F
IC
SpoSPBC31E1.02c
GO:0008554 sodium-exporting ATPase activity, phosphorylative
mechanism		 F
IDA
SceS000002447
IGI
SceS000002446
S000002447
ISS
SceS000002446
GO:0008556 potassium-transporting ATPase activity F
IMP
SceS000002446
S000002447
GO:0015410 manganese-transporting ATPase activity F
IDA
CelWBGene00004063
SceS000003135
IMP
AthAt1g10130
TAS
SpoSPBC31E1.02c
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
IGI
SceS000002446
ISS
SceS000002445
S000002446
GO:0030145 manganese ion binding F
IC
SpoSPBC31E1.02c
GO:0031490 chromatin DNA binding F
IPI
CelWBGene00004736
GO:0000003 reproduction P
IMP
CelWBGene00004736
GO:0002119 nematode larval development P
IMP
CelWBGene00004736
GO:0006200 ATP catabolic process P
ISS
SpoSPBC31E1.02c
TAS
SpoSPBC839.06
GO:0006486 protein amino acid glycosylation P
IMP
SpoSPBC31E1.02c
GO:0006813 potassium ion transport P
IMP
SceS000002446
S000002447
GO:0006814 sodium ion transport P
IGI
SceS000002446
S000002447
ISS
SceS000002445
GO:0006816 calcium ion transport P
IDA
CelWBGene00004063
SceS000003135
IGI
AthAt1g07810
IMP
SceS000003135
ISS
AthAt1g10130
At4g00900
GO:0006828 manganese ion transport P
IDA
CelWBGene00004063
SceS000003135
IGI
AthAt1g10130
At1g07810
GO:0006874 cellular calcium ion homeostasis P
IGI
SpoSPBC31E1.02c
IMP
CelWBGene00004736
TAS
SpoSPBC839.06
GO:0006887 exocytosis P
IGI
SceS000003135
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00004736
GO:0006950 response to stress P
IMP
CelWBGene00004063
GO:0006972 hyperosmotic response P
IGI
SceS000002447
GO:0006979 response to oxidative stress P
IMP
CelWBGene00004063
GO:0007047 cellular cell wall organization P
IMP
SpoSPBC31E1.02c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004736
GO:0009117 nucleotide metabolic process P
RCA
SceS000002446
GO:0009268 response to pH P
IGI
SceS000002447
GO:0009651 response to salt stress P
IGI
SceS000002447
IMP
SceS000002447
GO:0009790 embryo development P
IMP
CelWBGene00004736
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004736
GO:0010042 response to manganese ion P
IMP
AthAt1g07810
CelWBGene00004063
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00004736
GO:0030026 cellular manganese ion homeostasis P
IGI
AthAt1g07810
IMP
SpoSPBC31E1.02c
GO:0030104 water homeostasis P
IMP
CelWBGene00004736
GO:0030968 endoplasmic reticulum unfolded protein
response		 P
IGI
CelWBGene00004736
GO:0033205 cell cycle cytokinesis P
IMP
SpoSPBC31E1.02c
GO:0040007 growth P
IMP
CelWBGene00004736
GO:0040024 dauer larval development P
IGI
CelWBGene00004736
GO:0042149 cellular response to glucose starvation P
IMP
SceS000002447
GO:0046686 response to cadmium ion P
IEP
AthAt1g07810
GO:0048364 root development P
IMP
AthAt1g10130
GO:0050801 ion homeostasis P
RCA
SceS000003135
S000002447
GO:0050850 positive regulation of calcium-mediated
signaling		 P
IMP
SpoSPBC31E1.02c
GO:0051181 cofactor transport P
RCA
SceS000002446
S000002447
GO:0051592 response to calcium ion P
IMP
CelWBGene00004063
GO:0055071 manganese ion homeostasis P
IMP
AthAt1g10130
GO:0055085 transmembrane transport P
IDA
SceS000002447
IMP
SceS000002446
S000002447
ISS
SceS000002445
GO:0070588 calcium ion transmembrane transport P
IGI
SpoSPBC31E1.02c
IMP
SpoSPBC839.06
GO:0071421 manganese ion transmembrane transport P
IMP
SpoSPBC31E1.02c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68632

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) cta3
(SPBC839.06)		 GI:19112038 P22189
Saccharomyces cerevisiae (Sce) ENA5
(S000002445)		 GI:6320243 Q12691
Saccharomyces cerevisiae (Sce) ENA2
(S000002446)		 GI:6320244 Q01896
Saccharomyces cerevisiae (Sce) ENA1
(S000002447)		 GI:6320245 P13587
Kluyveromyces lactis (Kla) KLLA0F20658g GI:50311951
Kluyveromyces lactis (Kla) KLLA0E14630g GI:50309201
Eremothecium gossypii (Ego) AGOS_AGL097C GI:45201000
Magnaporthe grisea (Mgr) MGG_10730 GI:39941762
Magnaporthe grisea (Mgr) MGG_02074 GI:145605086
Neurospora crassa (Ncr) NCU05046.1 GI:32407810


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002445
S000002447
GO:0005624 membrane fraction C
IDA
SceS000002445
S000002446
S000002447
GO:0005739 mitochondrion C
IDA
SceS000002446
GO:0005886 plasma membrane C
IDA
SceS000002446
S000002447
ISS
SceS000002445
GO:0005388 calcium-transporting ATPase activity F
TAS
SpoSPBC839.06
GO:0008554 sodium-exporting ATPase activity, phosphorylative
mechanism		 F
IDA
SceS000002447
IGI
SceS000002446
S000002447
ISS
SceS000002446
GO:0008556 potassium-transporting ATPase activity F
IMP
SceS000002446
S000002447
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
IGI
SceS000002446
ISS
SceS000002445
S000002446
GO:0006200 ATP catabolic process P
TAS
SpoSPBC839.06
GO:0006813 potassium ion transport P
IMP
SceS000002446
S000002447
GO:0006814 sodium ion transport P
IGI
SceS000002446
S000002447
ISS
SceS000002445
GO:0006874 cellular calcium ion homeostasis P
TAS
SpoSPBC839.06
GO:0006972 hyperosmotic response P
IGI
SceS000002447
GO:0009117 nucleotide metabolic process P
RCA
SceS000002446
GO:0009268 response to pH P
IGI
SceS000002447
GO:0009651 response to salt stress P
IGI
SceS000002447
IMP
SceS000002447
GO:0042149 cellular response to glucose starvation P
IMP
SceS000002447
GO:0050801 ion homeostasis P
RCA
SceS000002447
GO:0051181 cofactor transport P
RCA
SceS000002446
S000002447
GO:0055085 transmembrane transport P
IDA
SceS000002447
IMP
SceS000002446
S000002447
ISS
SceS000002445
GO:0070588 calcium ion transmembrane transport P
IMP
SpoSPBC839.06

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_6806

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4215 AGL097C
Candida glabrata (Cgl) cgl4035 CAGL0K12034g
Cryptococcus neoformans (Cne) cne2251 181.m08271
Debaryomyces hansenii (Dha) dha1559 DEHA0C02937g
Debaryomyces hansenii (Dha) dha6140 DEHA0G09878g
Kluyveromyces lactis (Kla) kla3606 KLLA0E14630g
Kluyveromyces lactis (Kla) kla5007 KLLA0F20658g
Neurospora crassa (Ncr) ncr4898 NCU05046.2
Neurospora crassa (Ncr) ncr7758 NCU07966.2
Saccharomyces cerevisiae (Sce) sce1072 YDR038C
(S000002445)
Saccharomyces cerevisiae (Sce) sce1073 YDR039C
(S000002446)
Saccharomyces cerevisiae (Sce) sce1074 YDR040C
(S000002447)
Schizosaccharomyces pombe (Spo) spo851 SPBC839.06 P22189
Yarrowia lipolytica (Yli) yli37 YALI0A01023g
Yarrowia lipolytica (Yli) yli4659 YALI0E19338g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002445
S000002447
GO:0005624 membrane fraction C
IDA
SceS000002445
S000002446
S000002447
GO:0005739 mitochondrion C
IDA
SceS000002446
GO:0005886 plasma membrane C
IDA
SceS000002446
S000002447
ISS
SceS000002445
GO:0005388 calcium-transporting ATPase activity F
TAS
SpoSPBC839.06
GO:0008554 sodium-exporting ATPase activity, phosphorylative
mechanism		 F
IDA
SceS000002447
IGI
SceS000002446
S000002447
ISS
SceS000002446
GO:0008556 potassium-transporting ATPase activity F
IMP
SceS000002446
S000002447
GO:0015662 ATPase activity, coupled to transmembrane movement
of ions, phosphorylative mechanism		 F
IGI
SceS000002446
ISS
SceS000002445
S000002446
GO:0006200 ATP catabolic process P
TAS
SpoSPBC839.06
GO:0006813 potassium ion transport P
IMP
SceS000002446
S000002447
GO:0006814 sodium ion transport P
IGI
SceS000002446
S000002447
ISS
SceS000002445
GO:0006874 cellular calcium ion homeostasis P
TAS
SpoSPBC839.06
GO:0006972 hyperosmotic response P
IGI
SceS000002447
GO:0009117 nucleotide metabolic process P
RCA
SceS000002446
GO:0009268 response to pH P
IGI
SceS000002447
GO:0009651 response to salt stress P
IGI
SceS000002447
IMP
SceS000002447
GO:0042149 cellular response to glucose starvation P
IMP
SceS000002447
GO:0050801 ion homeostasis P
RCA
SceS000002447
GO:0051181 cofactor transport P
RCA
SceS000002446
S000002447
GO:0055085 transmembrane transport P
IDA
SceS000002447
IMP
SceS000002446
S000002447
ISS
SceS000002445
GO:0070588 calcium ion transmembrane transport P
IMP
SpoSPBC839.06

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC839.06
(P22189)		 YDR040C
(S000002447)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002447
GO:0005624 membrane fraction C
IDA
SceS000002447
GO:0005886 plasma membrane C
IDA
SceS000002447
GO:0005388 calcium-transporting ATPase activity F
TAS
SpoSPBC839.06
GO:0008554 sodium-exporting ATPase activity, phosphorylative
mechanism		 F
IDA
SceS000002447
IGI
SceS000002447
GO:0008556 potassium-transporting ATPase activity F
IMP
SceS000002447
GO:0006200 ATP catabolic process P
TAS
SpoSPBC839.06
GO:0006813 potassium ion transport P
IMP
SceS000002447
GO:0006814 sodium ion transport P
IGI
SceS000002447
GO:0006874 cellular calcium ion homeostasis P
TAS
SpoSPBC839.06
GO:0006972 hyperosmotic response P
IGI
SceS000002447
GO:0009268 response to pH P
IGI
SceS000002447
GO:0009651 response to salt stress P
IGI
SceS000002447
IMP
SceS000002447
GO:0042149 cellular response to glucose starvation P
IMP
SceS000002447
GO:0050801 ion homeostasis P
RCA
SceS000002447
GO:0051181 cofactor transport P
RCA
SceS000002447
GO:0055085 transmembrane transport P
IDA
SceS000002447
IMP
SceS000002447
GO:0070588 calcium ion transmembrane transport P
IMP
SpoSPBC839.06

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GO info in one table:

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