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Search term: YDR044W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HEM13
SGD link S000002451
Alternative ID YDR044W
Description Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
Synonyms YDR044W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1518 A-DHYP-

KOGs classification KOGs description
METABOLISM Coproporphyrinogen III oxidase CPO/HEM13

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03475 GI:15218820
Drosophila melanogaster (Dme) 7297203
(FBgn0021944)		 GI:17864388
Homo sapiens (Hsa) Hs20127406 GI:20127406
Saccharomyces cerevisiae (Sce) YDR044w
(S000002451)		 GI:6320249 P11353
Schizosaccharomyces pombe (Spo) SPAC222.11 GI:19114062 Q9UTE2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.11
GO:0005739 mitochondrion C
ISS
DmeFBgn0021944
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPAC222.11
GO:0005829 cytosol C
IDA
SceS000002451
SpoSPAC222.11
GO:0009507 chloroplast C
IDA
AthAt1g03475
GO:0009536 plastid C
IDA
AthAt1g03475
GO:0009570 chloroplast stroma C
IDA
AthAt1g03475
GO:0048046 apoplast C
IDA
AthAt1g03475
GO:0004109 coproporphyrinogen oxidase activity F
IDA
SceS000002451
IGI
AthAt1g03475
IMP
SceS000002451
ISS
AthAt1g03475
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0042803 protein homodimerization activity F
ISS
SpoSPAC222.11
GO:0006414 translational elongation P
RCA
SceS000002451
GO:0006783 heme biosynthetic process P
IMP
SceS000002451
ISS
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0033014 tetrapyrrole biosynthetic process P
IC
AthAt1g03475
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002451

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
76

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CPOX GI:41393599
Pan troglodytes (Ptr) CPOX GI:114588132
Mus musculus (Mmu) Cpox
(MGI:104841)		 GI:6681007 P36552
Rattus norvegicus (Rno) Cpox
(RGD:1311817)		 GI:79749365
Gallus gallus (Gga) CPOX GI:50729640
Drosophila melanogaster (Dme) Coprox
(FBgn0021944)		 GI:17864388
Anopheles gambiae (Aga) AgaP_AGAP004749 GI:158297942
Schizosaccharomyces pombe (Spo) hem13
(SPAC222.11)		 GI:19114062 Q9UTE2
Saccharomyces cerevisiae (Sce) HEM13
(S000002451)		 GI:6320249 P11353
Kluyveromyces lactis (Kla) KLLA0F18546g GI:50311765
Eremothecium gossypii (Ego) AGOS_AGR030C GI:45201125
Magnaporthe grisea (Mgr) MGG_01061 GI:145610607
Neurospora crassa (Ncr) NCU01546.1 GI:32415011
Arabidopsis thaliana (Ath) LIN2 GI:15218820
Oryza sativa (Osa) Os04g0610800 GI:115460466
Plasmodium falciparum (Pfa) PF11_0436 GI:124804765


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.11
GO:0005737 cytoplasm C
IDA
HsaCPOX
GO:0005739 mitochondrion C
IDA
HsaCPOX
MmuMGI:104841
ISO
MmuMGI:104841
ISS
DmeFBgn0021944
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPAC222.11
GO:0005758 mitochondrial intermembrane space C
ISO
MmuMGI:104841
GO:0005829 cytosol C
IDA
SceS000002451
SpoSPAC222.11
GO:0009507 chloroplast C
IDA
AthLIN2
GO:0009536 plastid C
IDA
AthLIN2
GO:0009570 chloroplast stroma C
IDA
AthLIN2
GO:0048046 apoplast C
IDA
AthLIN2
GO:0004109 coproporphyrinogen oxidase activity F
IDA
MmuMGI:104841
SceS000002451
IGI
AthLIN2
IMP
SceS000002451
ISO
MmuMGI:104841
ISS
AthLIN2
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0042802 identical protein binding F
ISO
MmuMGI:104841
GO:0042803 protein homodimerization activity F
IDA
HsaCPOX
ISS
SpoSPAC222.11
GO:0006414 translational elongation P
RCA
SceS000002451
GO:0006783 heme biosynthetic process P
IDA
MmuMGI:104841
IMP
SceS000002451
ISS
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0033014 tetrapyrrole biosynthetic process P
IC
AthLIN2
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002451

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2748

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga82 ENSANGP00000010734
Ashbya gossypii (Ago) ago4340 AGR030C
Arabidopsis thaliana (Ath) ath288 At1g03475.1
Candida glabrata (Cgl) cgl4038 CAGL0K12100g
Cryptococcus neoformans (Cne) cne3337 167.m05798
Dictyostelium discoideum (Ddi) ddi12826 DDB0231414
Debaryomyces hansenii (Dha) dha5181 DEHA0F17798g
Drosophila melanogaster (Dme) dme1171 CG3433-PA
(FBgn0021944)
Danio rerio (Dre) dre22657 ENSDARP00000049432
Escherichia coli (Eco) eco2357 16130361
Takifugu rubripes (Fru) fru26316 SINFRUP00000133100
Gallus gallus (Gga) gga1791 ENSGALP00000024546
(CPOX)
Gallus gallus (Gga) gga1790 ENSGALP00000024547
Homo sapiens (Hsa) hsa22828 ENSP00000264193
(CPOX)		 P36551
Kluyveromyces lactis (Kla) kla4911 KLLA0F18546g
Mus musculus (Mmu) mmu10495 ENSMUSP00000055455
(MGI:104841)		 P36552
Neurospora crassa (Ncr) ncr1501 NCU01546.2
Oryza sativa (Osa) osa83114 8203.m00126
Plasmodium falciparum (Pfa) pfa885 PF11_0436
Rattus norvegicus (Rno) rno6954 ENSRNOP00000002257
(RGD:1311817)		 Q3B7D0
Saccharomyces cerevisiae (Sce) sce1078 YDR044W
(S000002451)
Schizosaccharomyces pombe (Spo) spo96 SPAC222.11 Q9UTE2
Yarrowia lipolytica (Yli) yli5101 YALI0E29975g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.11
GO:0005739 mitochondrion C
IDA
MmuMGI:104841
ISO
MmuMGI:104841
ISS
DmeFBgn0021944
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPAC222.11
GO:0005758 mitochondrial intermembrane space C
ISO
MmuMGI:104841
GO:0005829 cytosol C
IDA
SceS000002451
SpoSPAC222.11
GO:0009507 chloroplast C
IDA
AthAt1g03475
GO:0009536 plastid C
IDA
AthAt1g03475
GO:0009570 chloroplast stroma C
IDA
AthAt1g03475
GO:0048046 apoplast C
IDA
AthAt1g03475
GO:0004109 coproporphyrinogen oxidase activity F
IDA
MmuMGI:104841
SceS000002451
IGI
AthAt1g03475
IMP
SceS000002451
ISO
MmuMGI:104841
ISS
AthAt1g03475
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0042802 identical protein binding F
ISO
MmuMGI:104841
GO:0042803 protein homodimerization activity F
ISS
SpoSPAC222.11
GO:0006414 translational elongation P
RCA
SceS000002451
GO:0006783 heme biosynthetic process P
IDA
MmuMGI:104841
IMP
SceS000002451
ISS
DmeFBgn0021944
SpoSPAC222.11
NAS
DmeFBgn0021944
GO:0033014 tetrapyrrole biosynthetic process P
IC
AthAt1g03475
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002451

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC222.11
(Q9UTE2)		 YDR044W
(S000002451)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC222.11
GO:0005743 mitochondrial inner membrane C
ISS
SpoSPAC222.11
GO:0005829 cytosol C
IDA
SceS000002451
SpoSPAC222.11
GO:0004109 coproporphyrinogen oxidase activity F
IDA
SceS000002451
IMP
SceS000002451
ISS
SpoSPAC222.11
GO:0042803 protein homodimerization activity F
ISS
SpoSPAC222.11
GO:0006414 translational elongation P
RCA
SceS000002451
GO:0006783 heme biosynthetic process P
IMP
SceS000002451
ISS
SpoSPAC222.11
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002451

Back to the top
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GO info in one table:

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