YOGY Home YOGY Help

Search term: YDR069C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DOA4
SGD link S000002476
Alternative ID YDR069C
Description Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole
Synonyms YDR069C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1868 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin C-terminal hydrolase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g39370 GI:5738367
Caenorhabditis elegans (Cel) CE26210
(WBGene00013342)		 GI:17566062
Drosophila melanogaster (Dme) 7295645 GI:7295645
Drosophila melanogaster (Dme) 7300711 GI:7300711
Homo sapiens (Hsa) Hs10190742
(USP29)		 GI:10190742 Q9HBJ7
Homo sapiens (Hsa) Hs13994268
(USP26)		 GI:13994268 Q9BXU7
Homo sapiens (Hsa) Hs17441694 GI:17441694
Homo sapiens (Hsa) Hs21265129 GI:21265129
Homo sapiens (Hsa) Hs21361712 GI:16552833 O75604
Homo sapiens (Hsa) Hs22045513 GI:22045513
Homo sapiens (Hsa) Hs22056581 GI:22056581
Homo sapiens (Hsa) Hs4827054 GI:4827054
Homo sapiens (Hsa) Hs6912742 GI:6912742
Homo sapiens (Hsa) HsM19923759 GI:15314773
Homo sapiens (Hsa) HsM7706755 GI:7706755
Saccharomyces cerevisiae (Sce) YDR069c
(S000002476)		 GI:6320274 P32571
Saccharomyces cerevisiae (Sce) YER144c
(S000000946)		 GI:6320992 P39944
Saccharomyces cerevisiae (Sce) YIL156w
(S000001418)		 GI:6322035 P40453
Saccharomyces cerevisiae (Sce) YKR098c
(S000001806)		 GI:6322951 P36026
Schizosaccharomyces pombe (Spo) SPBC18H10.08c GI:19112524 O60139
Encephalitozoon cuniculi (Ecu) ECU07g0410 GI:19074463 Q8SRL2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000000946
GO:0000502 proteasome complex C
IPI
SceS000002476
GO:0005575 cellular_component C
ND
HsaUSP29
SceS000001806
GO:0005624 membrane fraction C
IDA
SceS000002476
GO:0005634 nucleus C
IDA
HsaUSP26
GO:0005737 cytoplasm C
IC
SceS000001418
IDA
SpoSPBC18H10.08c
GO:0005739 mitochondrion C
IDA
SceS000002476
GO:0005768 endosome C
IDA
SceS000002476
GO:0005935 cellular bud neck C
IDA
SceS000000946
GO:0004175 endopeptidase activity F
IGI
SceS000002476
IPI
SceS000002476
GO:0004221 ubiquitin thiolesterase activity F
IDA
SceS000002476
IMP
SceS000002476
TAS
HsaUSP29
GO:0004843 ubiquitin-specific protease activity F
IDA
SceS000001806
S000002476
ISS
AthAt4g39370
TAS
SceS000000946
S000001418
GO:0005515 protein binding F
IPI
HsaUSP26
USP29
GO:0016741 transferase activity, transferring one-carbon
groups		 F
RCA
SceS000002476
GO:0006275 regulation of DNA replication P
IMP
SceS000002476
GO:0006464 protein modification process P
NAS
HsaUSP29
GO:0006508 proteolysis P
RCA
SceS000002476
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002476
GO:0006897 endocytosis P
IMP
SceS000002476
GO:0006914 autophagy P
RCA
SceS000002476
GO:0008150 biological_process P
ND
SceS000001806
GO:0010992 ubiquitin homeostasis P
IMP
SceS000002476
GO:0010995 free ubiquitin chain depolymerization P
IDA
SceS000002476
GO:0016579 protein deubiquitination P
IDA
HsaUSP26
TAS
SceS000001418
S000000946
S000002476
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002476
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002476
GO:0045184 establishment of protein localization P
RCA
SceS000002476
GO:0051049 regulation of transport P
RCA
SceS000000946

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38663

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) DOA4
(S000002476)		 GI:6320274 P32571
Kluyveromyces lactis (Kla) KLLA0E10252g GI:50308817
Eremothecium gossypii (Ego) AGOS_AFR007W GI:45198525


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002476
GO:0005624 membrane fraction C
IDA
SceS000002476
GO:0005739 mitochondrion C
IDA
SceS000002476
GO:0005768 endosome C
IDA
SceS000002476
GO:0004175 endopeptidase activity F
IGI
SceS000002476
IPI
SceS000002476
GO:0004221 ubiquitin thiolesterase activity F
IDA
SceS000002476
IMP
SceS000002476
GO:0004843 ubiquitin-specific protease activity F
IDA
SceS000002476
GO:0016741 transferase activity, transferring one-carbon
groups		 F
RCA
SceS000002476
GO:0006275 regulation of DNA replication P
IMP
SceS000002476
GO:0006508 proteolysis P
RCA
SceS000002476
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002476
GO:0006897 endocytosis P
IMP
SceS000002476
GO:0006914 autophagy P
RCA
SceS000002476
GO:0010992 ubiquitin homeostasis P
IMP
SceS000002476
GO:0010995 free ubiquitin chain depolymerization P
IDA
SceS000002476
GO:0016579 protein deubiquitination P
TAS
SceS000002476
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002476
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002476
GO:0045184 establishment of protein localization P
RCA
SceS000002476

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11624

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3199 AFR007W
Candida glabrata (Cgl) cgl1849 CAGL0G05247g
Candida glabrata (Cgl) cgl2815 CAGL0I06765g
Cryptococcus neoformans (Cne) cne2441 181.m08476
Debaryomyces hansenii (Dha) dha5565 DEHA0F26400g
Kluyveromyces lactis (Kla) kla3412 KLLA0E10252g
Rattus norvegicus (Rno) rno19638 ENSRNOP00000041810
Saccharomyces cerevisiae (Sce) sce1103 YDR069C
(S000002476)
Schizosaccharomyces pombe (Spo) spo3597 SPBC18H10.08c O60139
Yarrowia lipolytica (Yli) yli5992 YALI0F15367g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002476
GO:0005624 membrane fraction C
IDA
SceS000002476
GO:0005737 cytoplasm C
IDA
SpoSPBC18H10.08c
GO:0005739 mitochondrion C
IDA
SceS000002476
GO:0005768 endosome C
IDA
SceS000002476
GO:0004175 endopeptidase activity F
IGI
SceS000002476
IPI
SceS000002476
GO:0004221 ubiquitin thiolesterase activity F
IDA
SceS000002476
IMP
SceS000002476
GO:0004843 ubiquitin-specific protease activity F
IDA
SceS000002476
GO:0016741 transferase activity, transferring one-carbon
groups		 F
RCA
SceS000002476
GO:0006275 regulation of DNA replication P
IMP
SceS000002476
GO:0006508 proteolysis P
RCA
SceS000002476
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002476
GO:0006897 endocytosis P
IMP
SceS000002476
GO:0006914 autophagy P
RCA
SceS000002476
GO:0010992 ubiquitin homeostasis P
IMP
SceS000002476
GO:0010995 free ubiquitin chain depolymerization P
IDA
SceS000002476
GO:0016579 protein deubiquitination P
TAS
SceS000002476
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002476
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002476
GO:0045184 establishment of protein localization P
RCA
SceS000002476

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC18H10.08c
(O60139)		 YDR069C
(S000002476)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002476
GO:0005624 membrane fraction C
IDA
SceS000002476
GO:0005737 cytoplasm C
IDA
SpoSPBC18H10.08c
GO:0005739 mitochondrion C
IDA
SceS000002476
GO:0005768 endosome C
IDA
SceS000002476
GO:0004175 endopeptidase activity F
IGI
SceS000002476
IPI
SceS000002476
GO:0004221 ubiquitin thiolesterase activity F
IDA
SceS000002476
IMP
SceS000002476
GO:0004843 ubiquitin-specific protease activity F
IDA
SceS000002476
GO:0016741 transferase activity, transferring one-carbon
groups		 F
RCA
SceS000002476
GO:0006275 regulation of DNA replication P
IMP
SceS000002476
GO:0006508 proteolysis P
RCA
SceS000002476
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002476
GO:0006897 endocytosis P
IMP
SceS000002476
GO:0006914 autophagy P
RCA
SceS000002476
GO:0010992 ubiquitin homeostasis P
IMP
SceS000002476
GO:0010995 free ubiquitin chain depolymerization P
IDA
SceS000002476
GO:0016579 protein deubiquitination P
TAS
SceS000002476
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002476
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SceS000002476
GO:0045184 establishment of protein localization P
RCA
SceS000002476

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk