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Search term: YDR075W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PPH3
SGD link S000002482
Alternative ID YDR075W
Description Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p
Synonyms YDR075W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0372 ACDHYPE

KOGs classification KOGs description
METABOLISMCELLULAR PROCESSES AND SIGNALING Serine/threonine specific protein phosphatase involved in glycogen accumulation, PP2A-related

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g26720 GI:15236841
Arabidopsis thaliana (Ath) At5g55260 GI:15240488
Caenorhabditis elegans (Cel) CE22221
(WBGene00004086)		 GI:17554398
Caenorhabditis elegans (Cel) CE23041
(WBGene00004085)		 GI:17554396 Q9XW79
Drosophila melanogaster (Dme) 7294665 GI:7294665
Drosophila melanogaster (Dme) 7295595
(FBgn0023177)		 GI:17864424
Homo sapiens (Hsa) Hs4506027
(PPP4C)		 GI:4506027 P60510
Saccharomyces cerevisiae (Sce) YDR075w
(S000002482)		 GI:6320280 P32345
Saccharomyces cerevisiae (Sce) YNR032w
(S000005315)		 GI:6324359 P32838
Schizosaccharomyces pombe (Spo) SPAC22H10.04 GI:19114652 Q10298
Schizosaccharomyces pombe (Spo) SPBC26H8.05c GI:19113438 O74789
Encephalitozoon cuniculi (Ecu) ECU09g0980 GI:19173220
Encephalitozoon cuniculi (Ecu) ECU10g1280 GI:19074737 Q8SR19
Arabidopsis thaliana (Ath) At4g26720 GI:15236841
Arabidopsis thaliana (Ath) At5g55260 GI:15240488
Caenorhabditis elegans (Cel) CE22221
(WBGene00004086)		 GI:17554398
Caenorhabditis elegans (Cel) CE23041
(WBGene00004085)		 GI:17554396 Q9XW79
Drosophila melanogaster (Dme) 7294665 GI:7294665
Drosophila melanogaster (Dme) 7295595
(FBgn0023177)		 GI:17864424
Homo sapiens (Hsa) Hs4506027
(PPP4C)		 GI:4506027 P60510
Saccharomyces cerevisiae (Sce) YDR075w
(S000002482)		 GI:6320280 P32345
Saccharomyces cerevisiae (Sce) YNR032w
(S000005315)		 GI:6324359 P32838
Schizosaccharomyces pombe (Spo) SPAC22H10.04 GI:19114652 Q10298
Schizosaccharomyces pombe (Spo) SPBC26H8.05c GI:19113438 O74789
Encephalitozoon cuniculi (Ecu) ECU09g0980 GI:19173220
Encephalitozoon cuniculi (Ecu) ECU10g1280 GI:19074737 Q8SR19
Arabidopsis thaliana (Ath) At4g26720 GI:15236841
Arabidopsis thaliana (Ath) At5g55260 GI:15240488
Caenorhabditis elegans (Cel) CE22221
(WBGene00004086)		 GI:17554398
Caenorhabditis elegans (Cel) CE23041
(WBGene00004085)		 GI:17554396 Q9XW79
Drosophila melanogaster (Dme) 7294665 GI:7294665
Drosophila melanogaster (Dme) 7295595
(FBgn0023177)		 GI:17864424
Homo sapiens (Hsa) Hs4506027
(PPP4C)		 GI:4506027 P60510
Saccharomyces cerevisiae (Sce) YDR075w
(S000002482)		 GI:6320280 P32345
Saccharomyces cerevisiae (Sce) YNR032w
(S000005315)		 GI:6324359 P32838
Schizosaccharomyces pombe (Spo) SPAC22H10.04 GI:19114652 Q10298
Schizosaccharomyces pombe (Spo) SPBC26H8.05c GI:19113438 O74789
Encephalitozoon cuniculi (Ecu) ECU09g0980 GI:19173220
Encephalitozoon cuniculi (Ecu) ECU10g1280 GI:19074737 Q8SR19


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g55260
GO:0005634 nucleus C
IDA
AthAt4g26720
DmeFBgn0023177
SceS000002482
S000005315
SpoSPBC26H8.05c
ISS
SpoSPAC22H10.04
NAS
HsaPPP4C
GO:0005737 cytoplasm C
IDA
AthAt4g26720
DmeFBgn0023177
SceS000002482
S000005315
ISS
SpoSPAC22H10.04
GO:0005813 centrosome C
IDA
DmeFBgn0023177
NAS
HsaPPP4C
GO:0005829 cytosol C
IDA
SpoSPBC26H8.05c
GO:0004704 NF-kappaB-inducing kinase activity F
NAS
HsaPPP4C
GO:0004721 phosphoprotein phosphatase activity F
ISS
SpoSPBC26H8.05c
GO:0004722 protein serine/threonine phosphatase
activity		 F
IDA
SceS000002482
ISS
AthAt5g55260
At4g26720
DmeFBgn0023177
SceS000005315
SpoSPAC22H10.04
NAS
DmeFBgn0023177
HsaPPP4C
GO:0005515 protein binding F
IPI
HsaPPP4C
GO:0046872 metal ion binding F
NAS
HsaPPP4C
GO:0000003 reproduction P
IMP
CelWBGene00004085
GO:0000072 M phase specific microtubule process P
IMP
DmeFBgn0023177
GO:0000226 microtubule cytoskeleton organization P
NAS
HsaPPP4C
GO:0000278 mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0002119 nematode larval development P
IMP
CelWBGene00004086
WBGene00004085
GO:0005977 glycogen metabolic process P
IMP
SceS000005315
GO:0006470 protein amino acid dephosphorylation P
IC
SpoSPBC26H8.05c
IDA
SceS000002482
ISS
DmeFBgn0023177
SceS000005315
SpoSPAC22H10.04
NAS
DmeFBgn0023177
GO:0006807 nitrogen compound metabolic process P
IMP
SceS000002482
GO:0007017 microtubule-based process P
IMP
DmeFBgn0023177
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004085
GO:0007126 meiosis P
IMP
CelWBGene00004085
GO:0007165 signal transduction P
NAS
SpoSPAC22H10.04
SPBC26H8.05c
GO:0007346 regulation of mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0008150 biological_process P
ND
AthAt4g26720
At5g55260
GO:0009451 RNA modification P
RCA
SceS000002482
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004085
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000002482
GO:0018991 oviposition P
IMP
CelWBGene00004085
WBGene00004086
GO:0040007 growth P
IMP
CelWBGene00004085
GO:0042493 response to drug P
IMP
SceS000002482

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2038

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PPP4C GI:4506027 P60510
Pan troglodytes (Ptr) PPP4C GI:114661947
Canis familiaris (Cfa) PPP4C GI:73958492
Mus musculus (Mmu) Ppp4c
(MGI:1891763)		 GI:9790175 P97470
Rattus norvegicus (Rno) Ppp4c
(RGD:621225)		 GI:62719327
Drosophila melanogaster (Dme) Pp4-19C
(FBgn0023177)		 GI:17864424
Anopheles gambiae (Aga) AgaP_AGAP003779 GI:118780666
Caenorhabditis elegans (Cel) pph-4.1
(CE23041;
WBGene00004085)		 GI:17554396 Q9XW79
Schizosaccharomyces pombe (Spo) SPBC26H8.05c GI:19113438 O74789
Saccharomyces cerevisiae (Sce) PPH3
(S000002482)		 GI:6320280 P32345
Kluyveromyces lactis (Kla) KLLA0E10032g GI:50308797
Eremothecium gossypii (Ego) AGOS_AGR136W GI:54299400
Magnaporthe grisea (Mgr) MGG_01528 GI:145613572
Arabidopsis thaliana (Ath) PPX1 GI:15236841
Arabidopsis thaliana (Ath) PPX2 GI:15240488
Oryza sativa (Osa) Os09g0284200 GI:115478358
Plasmodium falciparum (Pfa) PFI1360c GI:124507101


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthPPX2
GO:0005634 nucleus C
IDA
AthPPX1
DmeFBgn0023177
SceS000002482
SpoSPBC26H8.05c
NAS
HsaPPP4C
GO:0005737 cytoplasm C
IDA
AthPPX1
DmeFBgn0023177
SceS000002482
GO:0005813 centrosome C
IDA
DmeFBgn0023177
NAS
HsaPPP4C
GO:0005829 cytosol C
IDA
SpoSPBC26H8.05c
GO:0004704 NF-kappaB-inducing kinase activity F
NAS
HsaPPP4C
MmuMGI:1891763
GO:0004721 phosphoprotein phosphatase activity F
ISS
SpoSPBC26H8.05c
GO:0004722 protein serine/threonine phosphatase
activity		 F
IDA
SceS000002482
ISS
AthPPX2
PPX1
DmeFBgn0023177
NAS
DmeFBgn0023177
HsaPPP4C
MmuMGI:1891763
GO:0005515 protein binding F
IPI
HsaPPP4C
MmuMGI:1891763
GO:0046872 metal ion binding F
NAS
HsaPPP4C
GO:0000003 reproduction P
IMP
CelWBGene00004085
GO:0000072 M phase specific microtubule process P
IMP
DmeFBgn0023177
GO:0000226 microtubule cytoskeleton organization P
NAS
HsaPPP4C
GO:0000278 mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0002119 nematode larval development P
IMP
CelWBGene00004085
GO:0006470 protein amino acid dephosphorylation P
IC
SpoSPBC26H8.05c
IDA
SceS000002482
ISS
DmeFBgn0023177
NAS
DmeFBgn0023177
GO:0006807 nitrogen compound metabolic process P
IMP
SceS000002482
GO:0007017 microtubule-based process P
IMP
DmeFBgn0023177
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004085
GO:0007126 meiosis P
IMP
CelWBGene00004085
GO:0007165 signal transduction P
NAS
MmuMGI:1891763
SpoSPBC26H8.05c
GO:0007346 regulation of mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0008150 biological_process P
ND
AthPPX1
PPX2
GO:0009451 RNA modification P
RCA
SceS000002482
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004085
GO:0016310 phosphorylation P
NAS
MmuMGI:1891763
GO:0016311 dephosphorylation P
NAS
MmuMGI:1891763
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000002482
GO:0018991 oviposition P
IMP
CelWBGene00004085
GO:0040007 growth P
IMP
CelWBGene00004085
GO:0042493 response to drug P
IMP
SceS000002482

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2652

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6261 ENSANGP00000015846
Ashbya gossypii (Ago) ago4447 AGR136W
Arabidopsis thaliana (Ath) ath20672 At4g26720.1
Arabidopsis thaliana (Ath) ath27519 At5g55260.1
Caenorhabditis elegans (Cel) cel20860 Y75B8A.30
(CE23041;
WBGene00004085)
Candida glabrata (Cgl) cgl3960 CAGL0K10208g
Cryptococcus neoformans (Cne) cne2575 181.m08766
Dictyostelium discoideum (Ddi) ddi12028 DDB0185222
Debaryomyces hansenii (Dha) dha5407 DEHA0F22869g
Drosophila melanogaster (Dme) dme18788 CG32505-PA
(FBgn0023177)
Drosophila melanogaster (Dme) dme18789 CG32505-PE
(FBgn0023177)
Danio rerio (Dre) dre17340 ENSDARP00000020819
(LOC562705)
Danio rerio (Dre) dre29561 ENSDARP00000045533
(ppp4c)		 Q7ZWF9
Takifugu rubripes (Fru) fru24639 SINFRUP00000129116
Homo sapiens (Hsa) hsa11980 ENSP00000279387
(PPP4C)		 P60510
Kluyveromyces lactis (Kla) kla3402 KLLA0E10032g
Mus musculus (Mmu) mmu25101 ENSMUSP00000032936
(MGI:1891763)		 P97470
Oryza sativa (Osa) osa48536 5669.m00170
Oryza sativa (Osa) osa63047 6614.m00149
Plasmodium falciparum (Pfa) pfa4738 PFI1360c
Rattus norvegicus (Rno) rno2994 ENSRNOP00000026909
(RGD:621225)		 Q5BJ92
Saccharomyces cerevisiae (Sce) sce1109 YDR075W
(S000002482)
Schizosaccharomyces pombe (Spo) spo4507 SPBC26H8.05c O74789
Yarrowia lipolytica (Yli) yli5784 YALI0F10505g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g55260
GO:0005634 nucleus C
IDA
AthAt4g26720
DmeFBgn0023177
SceS000002482
SpoSPBC26H8.05c
GO:0005737 cytoplasm C
IDA
AthAt4g26720
DmeFBgn0023177
SceS000002482
GO:0005813 centrosome C
IDA
DmeFBgn0023177
GO:0005829 cytosol C
IDA
SpoSPBC26H8.05c
GO:0004704 NF-kappaB-inducing kinase activity F
NAS
MmuMGI:1891763
GO:0004721 phosphoprotein phosphatase activity F
ISS
SpoSPBC26H8.05c
GO:0004722 protein serine/threonine phosphatase
activity		 F
IDA
SceS000002482
ISS
AthAt5g55260
At4g26720
DmeFBgn0023177
NAS
DmeFBgn0023177
MmuMGI:1891763
GO:0005515 protein binding F
IPI
MmuMGI:1891763
GO:0000003 reproduction P
IMP
CelWBGene00004085
GO:0000072 M phase specific microtubule process P
IMP
DmeFBgn0023177
GO:0000278 mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0002119 nematode larval development P
IMP
CelWBGene00004085
GO:0006470 protein amino acid dephosphorylation P
IC
SpoSPBC26H8.05c
IDA
SceS000002482
ISS
DmeFBgn0023177
NAS
DmeFBgn0023177
GO:0006807 nitrogen compound metabolic process P
IMP
SceS000002482
GO:0007017 microtubule-based process P
IMP
DmeFBgn0023177
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00004085
GO:0007126 meiosis P
IMP
CelWBGene00004085
GO:0007165 signal transduction P
NAS
MmuMGI:1891763
SpoSPBC26H8.05c
GO:0007346 regulation of mitotic cell cycle P
IMP
DmeFBgn0023177
GO:0008150 biological_process P
ND
AthAt4g26720
At5g55260
GO:0009451 RNA modification P
RCA
SceS000002482
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004085
GO:0016310 phosphorylation P
NAS
MmuMGI:1891763
GO:0016311 dephosphorylation P
NAS
MmuMGI:1891763
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000002482
GO:0018991 oviposition P
IMP
CelWBGene00004085
GO:0040007 growth P
IMP
CelWBGene00004085
GO:0042493 response to drug P
IMP
SceS000002482

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC26H8.05c
(O74789)		 YDR075W
(S000002482)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002482
SpoSPBC26H8.05c
GO:0005737 cytoplasm C
IDA
SceS000002482
GO:0005829 cytosol C
IDA
SpoSPBC26H8.05c
GO:0004721 phosphoprotein phosphatase activity F
ISS
SpoSPBC26H8.05c
GO:0004722 protein serine/threonine phosphatase
activity		 F
IDA
SceS000002482
GO:0006470 protein amino acid dephosphorylation P
IC
SpoSPBC26H8.05c
IDA
SceS000002482
GO:0006807 nitrogen compound metabolic process P
IMP
SceS000002482
GO:0007165 signal transduction P
NAS
SpoSPBC26H8.05c
GO:0009451 RNA modification P
RCA
SceS000002482
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000002482
GO:0042493 response to drug P
IMP
SceS000002482

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