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Search term: YDR080W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VPS41
SGD link S000002487
Alternative ID YDR080W
Description Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport
Synonyms YDR080W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2066 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Vacuolar assembly/sorting protein VPS41

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g08190 GI:15223152
Caenorhabditis elegans (Cel) CE16835_1 GI:17538620
Caenorhabditis elegans (Cel) CE29305_2 GI:17567427
Drosophila melanogaster (Dme) 7289410 GI:7289410
Homo sapiens (Hsa) Hs18105061 GI:18105061
Homo sapiens (Hsa) Hs7657677 GI:7657677
Saccharomyces cerevisiae (Sce) YDR080w
(S000002487)		 GI:6320285 P38959
Schizosaccharomyces pombe (Spo) SPAP27G11.05c GI:19114321 Q9P7N3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002487
RCA
SceS000002487
GO:0005737 cytoplasm C
IDA
SpoSPAP27G11.05c
GO:0005768 endosome C
IDA
SceS000002487
GO:0030897 HOPS complex C
IPI
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0033263 CORVET complex C
RCA
SceS000002487
GO:0000166 nucleotide binding F
ISS
AthAt1g08190
GO:0003674 molecular_function F
ND
SpoSPAP27G11.05c
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IPI
SceS000002487
GO:0035091 phosphoinositide binding F
IDA
SceS000002487
GO:0006623 protein targeting to vacuole P
ISS
SpoSPAP27G11.05c
TAS
AthAt1g08190
GO:0006624 vacuolar protein processing P
IMP
SceS000002487
GO:0006811 ion transport P
RCA
SceS000002487
GO:0006895 Golgi to endosome transport P
ISS
SpoSPAP27G11.05c
GO:0006914 autophagy P
RCA
SceS000002487
GO:0007033 vacuole organization P
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
RCA
SceS000002487
GO:0009630 gravitropism P
IMP
AthAt1g08190
GO:0015031 protein transport P
IMP
SceS000002487
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000002487
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000002487
GO:0035542 regulation of SNARE complex assembly P
IDA
SceS000002487
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000002487
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0045324 late endosome to vacuole transport P
ISS
SpoSPAP27G11.05c
GO:0048278 vesicle docking P
ISS
SpoSPAP27G11.05c
GO:0050801 ion homeostasis P
RCA
SceS000002487

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68635

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) VPS41
(S000002487)		 GI:6320285 P38959
Kluyveromyces lactis (Kla) KLLA0C11759g GI:50305531
Eremothecium gossypii (Ego) AGOS_AGR149W GI:45201245


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002487
RCA
SceS000002487
GO:0005768 endosome C
IDA
SceS000002487
GO:0030897 HOPS complex C
IPI
SceS000002487
GO:0033263 CORVET complex C
RCA
SceS000002487
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IPI
SceS000002487
GO:0035091 phosphoinositide binding F
IDA
SceS000002487
GO:0006624 vacuolar protein processing P
IMP
SceS000002487
GO:0006811 ion transport P
RCA
SceS000002487
GO:0006914 autophagy P
RCA
SceS000002487
GO:0007033 vacuole organization P
IMP
SceS000002487
RCA
SceS000002487
GO:0015031 protein transport P
IMP
SceS000002487
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000002487
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000002487
GO:0035542 regulation of SNARE complex assembly P
IDA
SceS000002487
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000002487
IMP
SceS000002487
GO:0050801 ion homeostasis P
RCA
SceS000002487

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1661

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11300 ENSANGP00000016789
Ashbya gossypii (Ago) ago4460 AGR149W
Arabidopsis thaliana (Ath) ath824 At1g08190.1
Caenorhabditis elegans (Cel) cel7853 F32A6.3
Candida glabrata (Cgl) cgl3954 CAGL0K10076g
Cryptococcus neoformans (Cne) cne77 162.m02793
Dictyostelium discoideum (Ddi) ddi7909 DDB0218852
Debaryomyces hansenii (Dha) dha1565 DEHA0C03069g
Drosophila melanogaster (Dme) dme15717 CG18028-PA
Drosophila melanogaster (Dme) dme15718 CG18028-PB
Drosophila melanogaster (Dme) dme15716 CG18028-PC
Danio rerio (Dre) dre16002 ENSDARP00000004267
Danio rerio (Dre) dre16004 ENSDARP00000031114
Danio rerio (Dre) dre16005 ENSDARP00000040036
Danio rerio (Dre) dre16006 ENSDARP00000042322
Danio rerio (Dre) dre16003 ENSDARP00000044028
Takifugu rubripes (Fru) fru19849 SINFRUP00000166853
Takifugu rubripes (Fru) fru19847 SINFRUP00000168782
Takifugu rubripes (Fru) fru19848 SINFRUP00000173266
Takifugu rubripes (Fru) fru19846 SINFRUP00000173760
Gallus gallus (Gga) gga10267 ENSGALP00000020075
(VPS41)		 Q5ZL70
Gallus gallus (Gga) gga10268 ENSGALP00000020076
Gallus gallus (Gga) gga10269 ENSGALP00000020077
Homo sapiens (Hsa) hsa28490 ENSP00000265745
(VPS41)		 Q75MS2
Homo sapiens (Hsa) hsa28489 ENSP00000309457
(VPS41)		 P49754-1
Kluyveromyces lactis (Kla) kla1724 KLLA0C11759g
Mus musculus (Mmu) mmu6553 ENSMUSP00000072729
(MGI:1929215)		 Q5KU39
Mus musculus (Mmu) mmu6554 ENSMUSP00000080045
Neurospora crassa (Ncr) ncr5738 NCU05902.2
Oryza sativa (Osa) osa45011 5370.m00119
Oryza sativa (Osa) osa79835 8145.m00150
Rattus norvegicus (Rno) rno13410 ENSRNOP00000017640
(RGD:1560511)
Saccharomyces cerevisiae (Sce) sce1115 YDR080W
(S000002487)
Schizosaccharomyces pombe (Spo) spo2851 SPAP27G11.05c Q9P7N3
Yarrowia lipolytica (Yli) yli6086 YALI0F17710g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002487
RCA
SceS000002487
GO:0005737 cytoplasm C
IDA
SpoSPAP27G11.05c
GO:0005768 endosome C
IDA
SceS000002487
GO:0005769 early endosome C
IDA
MmuMGI:1929215
GO:0005770 late endosome C
IDA
MmuMGI:1929215
GO:0005874 microtubule C
IDA
MmuMGI:1929215
GO:0030897 HOPS complex C
IPI
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0033263 CORVET complex C
RCA
SceS000002487
GO:0000166 nucleotide binding F
ISS
AthAt1g08190
GO:0003674 molecular_function F
ND
SpoSPAP27G11.05c
GO:0005515 protein binding F
IPI
MmuMGI:1929215
GO:0008017 microtubule binding F
IDA
MmuMGI:1929215
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IPI
SceS000002487
GO:0035091 phosphoinositide binding F
IDA
SceS000002487
GO:0006623 protein targeting to vacuole P
ISS
SpoSPAP27G11.05c
TAS
AthAt1g08190
GO:0006624 vacuolar protein processing P
IMP
SceS000002487
GO:0006811 ion transport P
RCA
SceS000002487
GO:0006895 Golgi to endosome transport P
ISS
SpoSPAP27G11.05c
GO:0006914 autophagy P
RCA
SceS000002487
GO:0007033 vacuole organization P
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
RCA
SceS000002487
GO:0008150 biological_process P
ND
MmuMGI:1929215
GO:0009630 gravitropism P
IMP
AthAt1g08190
GO:0015031 protein transport P
IMP
SceS000002487
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000002487
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000002487
GO:0035542 regulation of SNARE complex assembly P
IDA
SceS000002487
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000002487
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0045324 late endosome to vacuole transport P
ISS
SpoSPAP27G11.05c
GO:0048278 vesicle docking P
ISS
SpoSPAP27G11.05c
GO:0050801 ion homeostasis P
RCA
SceS000002487

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAP27G11.05c
(Q9P7N3)		 YDR080W
(S000002487)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002487
RCA
SceS000002487
GO:0005737 cytoplasm C
IDA
SpoSPAP27G11.05c
GO:0005768 endosome C
IDA
SceS000002487
GO:0030897 HOPS complex C
IPI
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0033263 CORVET complex C
RCA
SceS000002487
GO:0003674 molecular_function F
ND
SpoSPAP27G11.05c
GO:0017112 Rab guanyl-nucleotide exchange factor
activity		 F
IPI
SceS000002487
GO:0035091 phosphoinositide binding F
IDA
SceS000002487
GO:0006623 protein targeting to vacuole P
ISS
SpoSPAP27G11.05c
GO:0006624 vacuolar protein processing P
IMP
SceS000002487
GO:0006811 ion transport P
RCA
SceS000002487
GO:0006895 Golgi to endosome transport P
ISS
SpoSPAP27G11.05c
GO:0006914 autophagy P
RCA
SceS000002487
GO:0007033 vacuole organization P
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
RCA
SceS000002487
GO:0015031 protein transport P
IMP
SceS000002487
GO:0032889 regulation of vacuole fusion, non-autophagic P
IDA
SceS000002487
GO:0034727 piecemeal microautophagy of nucleus P
IMP
SceS000002487
GO:0035542 regulation of SNARE complex assembly P
IDA
SceS000002487
GO:0042144 vacuole fusion, non-autophagic P
IDA
SceS000002487
IMP
SceS000002487
ISS
SpoSPAP27G11.05c
GO:0045324 late endosome to vacuole transport P
ISS
SpoSPAP27G11.05c
GO:0048278 vesicle docking P
ISS
SpoSPAP27G11.05c
GO:0050801 ion homeostasis P
RCA
SceS000002487

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk