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Search term: YDR086C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SSS1
SGD link S000002493
Alternative ID YDR086C
Description Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p
Synonyms YDR086C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3498 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Preprotein translocase, gamma subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g48570 GI:18408660
Arabidopsis thaliana (Ath) At4g24920 GI:15234793
Arabidopsis thaliana (Ath) At5g50460 GI:15234793
Caenorhabditis elegans (Cel) CE05785
(WBGene00001303)		 GI:17559256 Q19967
Drosophila melanogaster (Dme) 7293621
(Sec61gamma)		 GI:19920362
Drosophila melanogaster (Dme) 7302378 GI:7302378 A1ZBU4
Homo sapiens (Hsa) Hs7657546 GI:6755450
Saccharomyces cerevisiae (Sce) YDR086c
(S000002493)		 GI:6320291 P35179
Schizosaccharomyces pombe (Spo) SPAC4G8.02c GI:19113973 Q09827
Encephalitozoon cuniculi (Ecu) ECU05g0885 GI:19173628 Q8SRW9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005623 cell C
IDA
CelWBGene00001303
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC4G8.02c
GO:0005784 Sec61 translocon complex C
IDA
SceS000002493
ISS
DmeSec61gamma
SpoSPAC4G8.02c
GO:0005886 plasma membrane C
IDA
AthAt3g48570
GO:0030176 integral to endoplasmic reticulum
membrane		 C
ISS
DmeSec61gamma
GO:0071261 Ssh1 translocon complex C
IDA
SceS000002493
GO:0005198 structural molecule activity F
IGI
SceS000002493
IMP
SceS000002493
GO:0008565 protein transporter activity F
ISS
DmeSec61gamma
SpoSPAC4G8.02c
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
SceS000002493
ISS
CelWBGene00001303
GO:0000003 reproduction P
IMP
CelWBGene00001303
GO:0001555 oocyte growth P
IMP
CelWBGene00001303
GO:0002119 nematode larval development P
IMP
CelWBGene00001303
GO:0006605 protein targeting P
ISS
AthAt5g50460
At4g24920
At3g48570
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
IMP
SceS000002493
ISS
DmeSec61gamma
SpoSPAC4G8.02c
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC4G8.02c
GO:0006886 intracellular protein transport P
ISS
AthAt3g48570
At5g50460
At4g24920
TAS
CelWBGene00001303
GO:0007040 lysosome organization P
IMP
DmeSec61gamma
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001303
GO:0010507 negative regulation of autophagy P
IMP
DmeSec61gamma
GO:0015031 protein transport P
ISS
DmeSec61gamma
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00001303
GO:0030728 ovulation P
IMP
CelWBGene00001303
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000002493
GO:0040007 growth P
IMP
CelWBGene00001303

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48621

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SSS1
(S000002493)		 GI:6320291 P35179
Kluyveromyces lactis (Kla) KLLA0C11957g GI:50305549
Eremothecium gossypii (Ego) AGOS_AGR157C GI:45201253


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005784 Sec61 translocon complex C
IDA
SceS000002493
GO:0071261 Ssh1 translocon complex C
IDA
SceS000002493
GO:0005198 structural molecule activity F
IGI
SceS000002493
IMP
SceS000002493
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
SceS000002493
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
IMP
SceS000002493
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000002493

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1805

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7835 ENSANGP00000019007
Ashbya gossypii (Ago) ago4468 AGR157C
Arabidopsis thaliana (Ath) ath20463 At4g24920.1
Arabidopsis thaliana (Ath) ath26974 At5g50460.1
Caenorhabditis elegans (Cel) cel7918 F32D8.6
(CE05785;
WBGene00001303)
Cryptococcus neoformans (Cne) cne2620 181.m08844
Dictyostelium discoideum (Ddi) ddi8745 DDB0187628
Drosophila melanogaster (Dme) dme6167 CG13426-PA
(FBgn0034510)
Drosophila melanogaster (Dme) dme18675 CG14214-PA
(FBgn0031049)
Drosophila melanogaster (Dme) dme4615 CG8860-PA
(FBgn0033691)
Encephalitozoon cuniculi (Ecu) ecu1190 19173628
Gallus gallus (Gga) gga26199 ENSGALP00000021367
(SEC61G)
Homo sapiens (Hsa) hsa28622 ENSP00000341538
(SEC61G)		 P60059
Kluyveromyces lactis (Kla) kla1733 KLLA0C11957g
Mus musculus (Mmu) mmu29271 ENSMUSP00000075927
Mus musculus (Mmu) mmu2717 ENSMUSP00000078309
Mus musculus (Mmu) mmu27321 ENSMUSP00000080591
Neurospora crassa (Ncr) ncr4003 NCU04127.2
Oryza sativa (Osa) osa1475 1925.m00142
Oryza sativa (Osa) osa28003 4222.m00122
Plasmodium falciparum (Pfa) pfa44 PFB0450w
Rattus norvegicus (Rno) rno10776 ENSRNOP00000006906
(RGD:1596170)		 B5DEL7
Rattus norvegicus (Rno) rno22965 ENSRNOP00000042879
(GI:100189555)		 Q7TQ10
Rattus norvegicus (Rno) rno29919 ENSRNOP00000044998
Saccharomyces cerevisiae (Sce) sce1121 YDR086C
(S000002493)
Schizosaccharomyces pombe (Spo) spo855 SPAC4G8.02c Q09827


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005623 cell C
IDA
CelWBGene00001303
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC4G8.02c
GO:0005784 Sec61 translocon complex C
IDA
SceS000002493
ISS
DmeFBgn0034510
FBgn0031049
FBgn0033691
SpoSPAC4G8.02c
GO:0030176 integral to endoplasmic reticulum
membrane		 C
ISS
DmeFBgn0031049
FBgn0033691
GO:0071261 Ssh1 translocon complex C
IDA
SceS000002493
GO:0005198 structural molecule activity F
IGI
SceS000002493
IMP
SceS000002493
GO:0008565 protein transporter activity F
ISS
DmeFBgn0031049
FBgn0034510
FBgn0033691
SpoSPAC4G8.02c
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
SceS000002493
ISS
CelWBGene00001303
GO:0000003 reproduction P
IMP
CelWBGene00001303
GO:0001555 oocyte growth P
IMP
CelWBGene00001303
GO:0002119 nematode larval development P
IMP
CelWBGene00001303
GO:0006605 protein targeting P
ISS
AthAt5g50460
At4g24920
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
IMP
SceS000002493
ISS
DmeFBgn0034510
FBgn0031049
FBgn0033691
PfaPFB0450w
SpoSPAC4G8.02c
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC4G8.02c
GO:0006886 intracellular protein transport P
ISS
AthAt5g50460
At4g24920
TAS
CelWBGene00001303
GO:0007040 lysosome organization P
IMP
DmeFBgn0031049
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001303
GO:0010507 negative regulation of autophagy P
IMP
DmeFBgn0031049
GO:0015031 protein transport P
ISS
DmeFBgn0031049
FBgn0033691
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00001303
GO:0030728 ovulation P
IMP
CelWBGene00001303
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000002493
GO:0040007 growth P
IMP
CelWBGene00001303

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC4G8.02c
(Q09827)		 YDR086C
(S000002493)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC4G8.02c
GO:0005784 Sec61 translocon complex C
IDA
SceS000002493
ISS
SpoSPAC4G8.02c
GO:0071261 Ssh1 translocon complex C
IDA
SceS000002493
GO:0005198 structural molecule activity F
IGI
SceS000002493
IMP
SceS000002493
GO:0008565 protein transporter activity F
ISS
SpoSPAC4G8.02c
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
IDA
SceS000002493
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
IMP
SceS000002493
ISS
SpoSPAC4G8.02c
GO:0006620 posttranslational protein targeting to
membrane		 P
ISS
SpoSPAC4G8.02c
GO:0031204 posttranslational protein targeting to membrane,
translocation		 P
IDA
SceS000002493

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GO info in one table:

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