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Search term: YDR113C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDS1
SGD link S000002520
Alternative ID YDR113C
Description Securin, inhibits anaphase by binding separin Esp1p; blocks cyclin destruction and mitotic exit, essential for meiotic progression and mitotic cell cycle arrest; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation
Synonyms YDR113C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38676

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PDS1
(S000002520)		 GI:6320318
Kluyveromyces lactis (Kla) KLLA0F19206g GI:50311823
Eremothecium gossypii (Ego) AGOS_AGR083W GI:45201178


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002520
GO:0005737 cytoplasm C
IDA
SceS000002520
GO:0005819 spindle C
IDA
SceS000002520
GO:0005515 protein binding F
IDA
SceS000002520
GO:0000070 mitotic sister chromatid segregation P
IMP
SceS000002520
IPI
SceS000002520
GO:0000725 recombinational repair P
IGI
SceS000002520
IMP
SceS000002520
GO:0007127 meiosis I P
IMP
SceS000002520
GO:0008104 protein localization P
IMP
SceS000002520
GO:0050790 regulation of catalytic activity P
RCA
SceS000002520
GO:0051726 regulation of cell cycle P
RCA
SceS000002520

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31449

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4393 AGR083W
Candida glabrata (Cgl) cgl4611 CAGL0L12298g
Kluyveromyces lactis (Kla) kla4942 KLLA0F19206g
Saccharomyces cerevisiae (Sce) sce1150 YDR113C
(S000002520)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002520
GO:0005737 cytoplasm C
IDA
SceS000002520
GO:0005819 spindle C
IDA
SceS000002520
GO:0005515 protein binding F
IDA
SceS000002520
GO:0000070 mitotic sister chromatid segregation P
IMP
SceS000002520
IPI
SceS000002520
GO:0000725 recombinational repair P
IGI
SceS000002520
IMP
SceS000002520
GO:0007127 meiosis I P
IMP
SceS000002520
GO:0008104 protein localization P
IMP
SceS000002520
GO:0050790 regulation of catalytic activity P
RCA
SceS000002520
GO:0051726 regulation of cell cycle P
RCA
SceS000002520

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC14C8.01c
(P21135)		 YDR113C
(S000002520)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002520
SpoSPBC14C8.01c
GO:0005737 cytoplasm C
IDA
SceS000002520
GO:0005819 spindle C
IDA
SceS000002520
SpoSPBC14C8.01c
GO:0005829 cytosol C
IDA
SpoSPBC14C8.01c
GO:0005515 protein binding F
IDA
SceS000002520
GO:0030414 peptidase inhibitor activity F
IMP
SpoSPBC14C8.01c
GO:0000070 mitotic sister chromatid segregation P
IMP
SceS000002520
IPI
SceS000002520
GO:0000725 recombinational repair P
IGI
SceS000002520
IMP
SceS000002520
GO:0006302 double-strand break repair P
IGI
SpoSPBC14C8.01c
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
NAS
SpoSPBC14C8.01c
GO:0007127 meiosis I P
IMP
SceS000002520
GO:0008104 protein localization P
IMP
SceS000002520
GO:0010466 negative regulation of peptidase
activity		 P
IMP
SpoSPBC14C8.01c
GO:0033048 negative regulation of mitotic sister chromatid
segregation		 P
IMP
SpoSPBC14C8.01c
GO:0034613 cellular protein localization P
IGI
SpoSPBC14C8.01c
GO:0050790 regulation of catalytic activity P
RCA
SceS000002520
GO:0051306 mitotic sister chromatid separation P
IMP
SpoSPBC14C8.01c
GO:0051726 regulation of cell cycle P
RCA
SceS000002520

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