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Search term: YDR118W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name APC4
SGD link S000002525
Alternative ID YDR118W
Description Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
Synonyms YDR118W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4640 A-DHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Anaphase-promoting complex (APC), subunit 4

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g21530 GI:15234498
Drosophila melanogaster (Dme) 7291001 GI:7291001 Q9W395
Homo sapiens (Hsa) Hs22044133 GI:22044133
Homo sapiens (Hsa) Hs7019329 GI:7019329
Saccharomyces cerevisiae (Sce) YDR118w
(S000002525)		 GI:6320323 Q04601
Schizosaccharomyces pombe (Spo) SPAC19G12.01c GI:19115328 O42839


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g21530
GO:0005634 nucleus C
IDA
SpoSPAC19G12.01c
GO:0005680 anaphase-promoting complex C
IDA
SceS000002525
SpoSPAC19G12.01c
GO:0005816 spindle pole body C
IDA
SpoSPAC19G12.01c
GO:0005829 cytosol C
IDA
SpoSPAC19G12.01c
GO:0032153 cell division site C
IDA
SpoSPAC19G12.01c
GO:0000166 nucleotide binding F
ISS
AthAt4g21530
GO:0004842 ubiquitin-protein ligase activity F
TAS
SceS000002525
GO:0005515 protein binding F
IPI
SpoSPAC19G12.01c
TAS
SceS000002525
GO:0000022 mitotic spindle elongation P
TAS
SceS000002525
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000002525
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000002525
GO:0008054 cyclin catabolic process P
TAS
SceS000002525
GO:0008150 biological_process P
ND
AthAt4g21530
GO:0016567 protein ubiquitination P
IC
SpoSPAC19G12.01c
IMP
SpoSPAC19G12.01c
IPI
SceS000002525
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
SpoSPAC19G12.01c
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
IPI
SceS000002525
ISS
SpoSPAC19G12.01c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31450

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4388 AGR078C
Candida glabrata (Cgl) cgl284 CAGL0B01859g
Kluyveromyces lactis (Kla) kla4947 KLLA0F19316g
Saccharomyces cerevisiae (Sce) sce1155 YDR118W
(S000002525)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005680 anaphase-promoting complex C
IDA
SceS000002525
GO:0004842 ubiquitin-protein ligase activity F
TAS
SceS000002525
GO:0005515 protein binding F
TAS
SceS000002525
GO:0000022 mitotic spindle elongation P
TAS
SceS000002525
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000002525
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000002525
GO:0008054 cyclin catabolic process P
TAS
SceS000002525
GO:0016567 protein ubiquitination P
IPI
SceS000002525
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
IPI
SceS000002525

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC19G12.01c
(O42839)		 YDR118W
(S000002525)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC19G12.01c
GO:0005680 anaphase-promoting complex C
IDA
SceS000002525
SpoSPAC19G12.01c
GO:0005816 spindle pole body C
IDA
SpoSPAC19G12.01c
GO:0005829 cytosol C
IDA
SpoSPAC19G12.01c
GO:0032153 cell division site C
IDA
SpoSPAC19G12.01c
GO:0004842 ubiquitin-protein ligase activity F
TAS
SceS000002525
GO:0005515 protein binding F
IPI
SpoSPAC19G12.01c
TAS
SceS000002525
GO:0000022 mitotic spindle elongation P
TAS
SceS000002525
GO:0000070 mitotic sister chromatid segregation P
TAS
SceS000002525
GO:0007091 mitotic metaphase/anaphase transition P
TAS
SceS000002525
GO:0008054 cyclin catabolic process P
TAS
SceS000002525
GO:0016567 protein ubiquitination P
IC
SpoSPAC19G12.01c
IMP
SpoSPAC19G12.01c
IPI
SceS000002525
GO:0030071 regulation of mitotic metaphase/anaphase
transition		 P
IMP
SpoSPAC19G12.01c
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
IPI
SceS000002525
ISS
SpoSPAC19G12.01c

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