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Search term: YDR120C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TRM1
SGD link S000002527
Alternative ID YDR120C
Description tRNA methyltransferase; two forms of the protein are made by alternative translation starts; localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
Synonyms YDR120C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1253 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING tRNA methyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g02320 GI:15232884
Arabidopsis thaliana (Ath) At3g56330 GI:15228894
Arabidopsis thaliana (Ath) At5g15810 GI:15242397
Caenorhabditis elegans (Cel) CE15201
(WBGene00006613)		 GI:17564890 Q23270
Drosophila melanogaster (Dme) 7297945
(FBgn0032430)		 GI:19921190
Homo sapiens (Hsa) Hs13569899 GI:13569899
Homo sapiens (Hsa) Hs17461291_1 GI:17461291
Homo sapiens (Hsa) Hs8923219_1 GI:8923219 Q9NXH9
Saccharomyces cerevisiae (Sce) YDR120c
(S000002527)		 GI:6320325 P15565
Schizosaccharomyces pombe (Spo) SPBC25D12.05 GI:19113339 Q9P804
Encephalitozoon cuniculi (Ecu) ECU08g1450 GI:19173470 Q8SR99
Arabidopsis thaliana (Ath) At3g02320 GI:15232884
Arabidopsis thaliana (Ath) At3g56330 GI:15228894
Arabidopsis thaliana (Ath) At5g15810 GI:15242397
Caenorhabditis elegans (Cel) CE15201
(WBGene00006613)		 GI:17564890 Q23270
Drosophila melanogaster (Dme) 7297945
(FBgn0032430)		 GI:19921190
Homo sapiens (Hsa) Hs13569899 GI:13569899
Homo sapiens (Hsa) Hs17461291_1 GI:17461291
Homo sapiens (Hsa) Hs8923219_1 GI:8923219 Q9NXH9
Saccharomyces cerevisiae (Sce) YDR120c
(S000002527)		 GI:6320325 P15565
Schizosaccharomyces pombe (Spo) SPBC25D12.05 GI:19113339 Q9P804
Encephalitozoon cuniculi (Ecu) ECU08g1450 GI:19173470 Q8SR99


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g15810
At3g02320
GO:0005634 nucleus C
IDA
SpoSPBC25D12.05
GO:0005635 nuclear envelope C
IDA
SceS000002527
GO:0005637 nuclear inner membrane C
IDA
SceS000002527
IMP
SceS000002527
GO:0005739 mitochondrion C
IDA
SceS000002527
SpoSPBC25D12.05
ISS
SpoSPBC25D12.05
GO:0031965 nuclear membrane C
ISS
SpoSPBC25D12.05
GO:0003723 RNA binding F
ISS
AthAt5g15810
At3g56330
At3g02320
GO:0004809 tRNA (guanine-N2-)-methyltransferase
activity		 F
IDA
SceS000002527
IMP
SceS000002527
ISS
AthAt3g56330
At3g02320
At5g15810
DmeFBgn0032430
SpoSPBC25D12.05
GO:0006400 tRNA modification P
ISS
DmeFBgn0032430
GO:0008033 tRNA processing P
ISS
AthAt5g15810
At3g02320
At3g56330
SpoSPBC25D12.05
GO:0009451 RNA modification P
RCA
SceS000002527
GO:0030488 tRNA methylation P
IMP
SceS000002527
ISS
SpoSPBC25D12.05
GO:0045184 establishment of protein localization P
RCA
SceS000002527

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5632

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TRMT1 GI:209862871
Pan troglodytes (Ptr) TRMT1 GI:55648391
Mus musculus (Mmu) Trmt1
(MGI:1289155)		 GI:37574126 Q3TD26
Rattus norvegicus (Rno) Trmt1
(RGD:1305992)		 GI:62078475
Drosophila melanogaster (Dme) CG6388
(FBgn0032430)		 GI:19921190
Anopheles gambiae (Aga) AgaP_AGAP009740 GI:158298627
Caenorhabditis elegans (Cel) trm-1
(CE15201;
WBGene00006613)		 GI:17564890 Q23270
Schizosaccharomyces pombe (Spo) trm1
(SPBC25D12.05)		 GI:19113339 Q9P804
Saccharomyces cerevisiae (Sce) TRM1
(S000002527)		 GI:6320325 P15565
Kluyveromyces lactis (Kla) KLLA0F19404g GI:50311839
Eremothecium gossypii (Ego) AGOS_AGR075W GI:45201170
Magnaporthe grisea (Mgr) MGG_01448 GI:145613672
Neurospora crassa (Ncr) NCU06336.1 GI:32411421
Oryza sativa (Osa) Os10g0357800 GI:115481662


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1289155
GO:0005634 nucleus C
IDA
SpoSPBC25D12.05
GO:0005635 nuclear envelope C
IDA
SceS000002527
GO:0005637 nuclear inner membrane C
IDA
SceS000002527
IMP
SceS000002527
GO:0005739 mitochondrion C
IDA
SceS000002527
SpoSPBC25D12.05
ISS
SpoSPBC25D12.05
GO:0031965 nuclear membrane C
ISS
SpoSPBC25D12.05
GO:0003674 molecular_function F
ND
MmuMGI:1289155
GO:0004809 tRNA (guanine-N2-)-methyltransferase
activity		 F
IDA
SceS000002527
IMP
SceS000002527
ISS
DmeFBgn0032430
SpoSPBC25D12.05
GO:0006400 tRNA modification P
ISS
DmeFBgn0032430
GO:0008033 tRNA processing P
ISS
SpoSPBC25D12.05
GO:0008150 biological_process P
ND
MmuMGI:1289155
GO:0009451 RNA modification P
RCA
SceS000002527
GO:0030488 tRNA methylation P
IMP
SceS000002527
ISS
SpoSPBC25D12.05
GO:0045184 establishment of protein localization P
RCA
SceS000002527

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_968

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11985 ENSANGP00000010185
Ashbya gossypii (Ago) ago4385 AGR075W
Arabidopsis thaliana (Ath) ath12246 At3g02320.1
Arabidopsis thaliana (Ath) ath23798 At5g15810.1
Caenorhabditis elegans (Cel) cel21293 ZC376.5
(CE15201;
WBGene00006613)
Candida glabrata (Cgl) cgl285 CAGL0B01881g
Cryptococcus neoformans (Cne) cne1887 181.m07855
Dictyostelium discoideum (Ddi) ddi8381 DDB0186078
Debaryomyces hansenii (Dha) dha4037 DEHA0E17952g
Drosophila melanogaster (Dme) dme2133 CG6388-PA
(FBgn0032430)
Danio rerio (Dre) dre2865 ENSDARP00000020665
Danio rerio (Dre) dre2864 ENSDARP00000022546
(LOC553298)		 Q5D012
Encephalitozoon cuniculi (Ecu) ecu301 19173470
Takifugu rubripes (Fru) fru9486 SINFRUP00000156525
Takifugu rubripes (Fru) fru9487 SINFRUP00000176969
Takifugu rubripes (Fru) fru9488 SINFRUP00000177383
Homo sapiens (Hsa) hsa15745 ENSP00000221504
(TRMT1)		 Q9NXH9-2
Homo sapiens (Hsa) hsa15744 ENSP00000319457
Homo sapiens (Hsa) hsa33500 ENSP00000331394
Homo sapiens (Hsa) hsa15746 ENSP00000350352
(TRMT1)		 Q9NXH9-1
Kluyveromyces lactis (Kla) kla4951 KLLA0F19404g
Mus musculus (Mmu) mmu26319 ENSMUSP00000001974
(MGI:1289155)		 Q3TX08
Neurospora crassa (Ncr) ncr6155 NCU06336.2
Oryza sativa (Osa) osa7716 2553.m00129
Oryza sativa (Osa) osa20418 3545.m00154
Oryza sativa (Osa) osa24546 3805.m00105
Oryza sativa (Osa) osa65313 6756.m00104
Oryza sativa (Osa) osa80831 8113.m00070
Oryza sativa (Osa) osa86421 9202.m00130
Plasmodium falciparum (Pfa) pfa4274 PF13_0109
Rattus norvegicus (Rno) rno14756 ENSRNOP00000003941
(RGD:1305992)		 Q5U4E4
Saccharomyces cerevisiae (Sce) sce1158 YDR120C
(S000002527)
Schizosaccharomyces pombe (Spo) spo2106 SPBC25D12.05 Q9P804
Yarrowia lipolytica (Yli) yli5129 YALI0E30723g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g15810
At3g02320
MmuMGI:1289155
GO:0005634 nucleus C
IDA
SpoSPBC25D12.05
GO:0005635 nuclear envelope C
IDA
SceS000002527
GO:0005637 nuclear inner membrane C
IDA
SceS000002527
IMP
SceS000002527
GO:0005739 mitochondrion C
IDA
SceS000002527
SpoSPBC25D12.05
ISS
SpoSPBC25D12.05
GO:0020011 apicoplast C
ISS
PfaPF13_0109
GO:0031965 nuclear membrane C
ISS
SpoSPBC25D12.05
GO:0003674 molecular_function F
ND
MmuMGI:1289155
GO:0003723 RNA binding F
ISS
AthAt5g15810
At3g02320
GO:0004809 tRNA (guanine-N2-)-methyltransferase
activity		 F
IDA
SceS000002527
IMP
SceS000002527
ISS
AthAt3g02320
At5g15810
DmeFBgn0032430
SpoSPBC25D12.05
GO:0006400 tRNA modification P
ISS
DmeFBgn0032430
PfaPF13_0109
GO:0008033 tRNA processing P
ISS
AthAt5g15810
At3g02320
SpoSPBC25D12.05
GO:0008150 biological_process P
ND
MmuMGI:1289155
GO:0009451 RNA modification P
RCA
SceS000002527
GO:0030488 tRNA methylation P
IMP
SceS000002527
ISS
SpoSPBC25D12.05
GO:0045184 establishment of protein localization P
RCA
SceS000002527

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC25D12.05
(Q9P804)		 YDR120C
(S000002527)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC25D12.05
GO:0005635 nuclear envelope C
IDA
SceS000002527
GO:0005637 nuclear inner membrane C
IDA
SceS000002527
IMP
SceS000002527
GO:0005739 mitochondrion C
IDA
SceS000002527
SpoSPBC25D12.05
ISS
SpoSPBC25D12.05
GO:0031965 nuclear membrane C
ISS
SpoSPBC25D12.05
GO:0004809 tRNA (guanine-N2-)-methyltransferase
activity		 F
IDA
SceS000002527
IMP
SceS000002527
ISS
SpoSPBC25D12.05
GO:0008033 tRNA processing P
ISS
SpoSPBC25D12.05
GO:0009451 RNA modification P
RCA
SceS000002527
GO:0030488 tRNA methylation P
IMP
SceS000002527
ISS
SpoSPBC25D12.05
GO:0045184 establishment of protein localization P
RCA
SceS000002527

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GO info in one table:

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