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Search term: YDR129C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SAC6
SGD link S000002536
Alternative ID YDR129C
Description Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton
Synonyms YDR129C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0046 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ca2+-binding actin-bundling protein (fimbrin/plastin), EF-Hand protein superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g04750 GI:15224051
Arabidopsis thaliana (Ath) At4g26700 GI:15236837
Arabidopsis thaliana (Ath) At5g35700 GI:15238586
Arabidopsis thaliana (Ath) At5g48460 GI:15238983
Arabidopsis thaliana (Ath) At5g55400 GI:15240502
Caenorhabditis elegans (Cel) CE26481
(WBGene00022424)		 GI:17544284
Caenorhabditis elegans (Cel) CE26598_2 GI:17570513 Q95XD8
Caenorhabditis elegans (Cel) CE27452
(WBGene00022425)		 GI:17544286
Drosophila melanogaster (Dme) 7293343
(FBgn0024238)		 GI:17647429 Q8IQZ8
Homo sapiens (Hsa) Hs4504965 GI:4504965
Homo sapiens (Hsa) Hs4505897 GI:4505897
Homo sapiens (Hsa) Hs17458722 GI:17458722
Homo sapiens (Hsa) Hs7549809
(PLS3)		 GI:7549809 P13797
Saccharomyces cerevisiae (Sce) YDR129c
(S000002536)		 GI:6320334 P32599
Schizosaccharomyces pombe (Spo) SPBC1778.06c GI:19113081 O59945
Arabidopsis thaliana (Ath) At2g04750 GI:15224051
Arabidopsis thaliana (Ath) At4g26700 GI:15236837
Arabidopsis thaliana (Ath) At5g35700 GI:15238586
Arabidopsis thaliana (Ath) At5g48460 GI:15238983
Arabidopsis thaliana (Ath) At5g55400 GI:15240502
Caenorhabditis elegans (Cel) CE26481
(WBGene00022424)		 GI:17544284
Caenorhabditis elegans (Cel) CE26598_2 GI:17570513 Q95XD8
Caenorhabditis elegans (Cel) CE27452
(WBGene00022425)		 GI:17544286
Drosophila melanogaster (Dme) 7293343
(FBgn0024238)		 GI:17647429 Q8IQZ8
Homo sapiens (Hsa) Hs4504965 GI:4504965
Homo sapiens (Hsa) Hs4505897 GI:4505897
Homo sapiens (Hsa) Hs17458722 GI:17458722
Homo sapiens (Hsa) Hs7549809
(PLS3)		 GI:7549809 P13797
Saccharomyces cerevisiae (Sce) YDR129c
(S000002536)		 GI:6320334 P32599
Schizosaccharomyces pombe (Spo) SPBC1778.06c GI:19113081 O59945
Arabidopsis thaliana (Ath) At2g04750 GI:15224051
Arabidopsis thaliana (Ath) At4g26700 GI:15236837
Arabidopsis thaliana (Ath) At5g35700 GI:15238586
Arabidopsis thaliana (Ath) At5g48460 GI:15238983
Arabidopsis thaliana (Ath) At5g55400 GI:15240502
Caenorhabditis elegans (Cel) CE26481
(WBGene00022424)		 GI:17544284
Caenorhabditis elegans (Cel) CE26598_2 GI:17570513 Q95XD8
Caenorhabditis elegans (Cel) CE27452
(WBGene00022425)		 GI:17544286
Drosophila melanogaster (Dme) 7293343
(FBgn0024238)		 GI:17647429 Q8IQZ8
Homo sapiens (Hsa) Hs4504965 GI:4504965
Homo sapiens (Hsa) Hs4505897 GI:4505897
Homo sapiens (Hsa) Hs17458722 GI:17458722
Homo sapiens (Hsa) Hs7549809
(PLS3)		 GI:7549809 P13797
Saccharomyces cerevisiae (Sce) YDR129c
(S000002536)		 GI:6320334 P32599
Schizosaccharomyces pombe (Spo) SPBC1778.06c GI:19113081 O59945


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g35700
At4g26700
GO:0005618 cell wall C
IDA
AthAt2g04750
GO:0005773 vacuole C
IDA
AthAt5g55400
GO:0005826 actomyosin contractile ring C
IDA
SpoSPBC1778.06c
GO:0030479 actin cortical patch C
IDA
SceS000002536
SpoSPBC1778.06c
GO:0032432 actin filament bundle C
IDA
SceS000002536
GO:0043332 mating projection tip C
IDA
SceS000002536
GO:0003674 molecular_function F
ND
AthAt2g04750
GO:0003779 actin binding F
IPI
SpoSPBC1778.06c
ISS
AthAt4g26700
DmeFBgn0024238
NAS
DmeFBgn0024238
GO:0005515 protein binding F
IPI
HsaPLS3
GO:0030674 protein binding, bridging F
IDA
SceS000002536
IPI
SpoSPBC1778.06c
GO:0051015 actin filament binding F
IDA
SceS000002536
TAS
SpoSPBC1778.06c
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPBC1778.06c
GO:0006897 endocytosis P
TAS
SceS000002536
GO:0006970 response to osmotic stress P
RCA
SceS000002536
TAS
SceS000002536
GO:0007015 actin filament organization P
IMP
SceS000002536
IPI
SceS000002536
GO:0007047 cellular cell wall organization P
RCA
SceS000002536
GO:0007121 bipolar cellular bud site selection P
TAS
SceS000002536
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPBC1778.06c
GO:0008150 biological_process P
ND
AthAt2g04750
At5g35700
At4g26700
At5g48460
GO:0008360 regulation of cell shape P
IGI
SpoSPBC1778.06c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022223
WBGene00022425
GO:0016321 female meiosis chromosome segregation P
IMP
DmeFBgn0024238
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPBC1778.06c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002536
GO:0030437 ascospore formation P
IMP
SpoSPBC1778.06c
GO:0030835 negative regulation of actin filament
depolymerization		 P
IMP
SpoSPBC1778.06c
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPBC1778.06c
GO:0048308 organelle inheritance P
RCA
SceS000002536
GO:0051017 actin filament bundle assembly P
IMP
SpoSPBC1778.06c
GO:0051049 regulation of transport P
RCA
SceS000002536
GO:0051666 actin cortical patch localization P
IMP
SpoSPBC1778.06c
GO:0051764 actin crosslink formation P
IPI
SpoSPBC1778.06c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68250

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PLS3 GI:7549809 P13797
Pan troglodytes (Ptr) PLS3 GI:114689904
Canis familiaris (Cfa) PLS3 GI:74008158
Mus musculus (Mmu) Pls3
(MGI:104807)		 GI:21704120 Q3UJG9
Rattus norvegicus (Rno) Pls3
(RGD:621409)		 GI:109510539
Gallus gallus (Gga) PLS3 GI:57530180
Schizosaccharomyces pombe (Spo) fim1
(SPBC1778.06c)		 GI:19113081 O59945
Saccharomyces cerevisiae (Sce) SAC6
(S000002536)		 GI:6320334 P32599
Kluyveromyces lactis (Kla) KLLA0F19778g GI:50311873
Eremothecium gossypii (Ego) AGOS_AGR069C GI:45201164
Magnaporthe grisea (Mgr) MGG_04478 GI:145603093
Neurospora crassa (Ncr) NCU03992.1 GI:32405396
Arabidopsis thaliana (Ath) FIM2 GI:15238586
Arabidopsis thaliana (Ath) AT2G04750 GI:15224051
Oryza sativa (Osa) Os02g0588300 GI:115446989


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthFIM2
GO:0005618 cell wall C
IDA
AthAt2g04750
GO:0005737 cytoplasm C
IDA
MmuMGI:104807
GO:0005826 actomyosin contractile ring C
IDA
SpoSPBC1778.06c
GO:0030479 actin cortical patch C
IDA
SceS000002536
SpoSPBC1778.06c
GO:0032420 stereocilium C
ISO
MmuMGI:104807
GO:0032432 actin filament bundle C
IDA
SceS000002536
GO:0043332 mating projection tip C
IDA
SceS000002536
GO:0003674 molecular_function F
ND
AthAt2g04750
MmuMGI:104807
GO:0003779 actin binding F
IPI
SpoSPBC1778.06c
GO:0005515 protein binding F
IPI
HsaPLS3
GO:0030674 protein binding, bridging F
IDA
SceS000002536
IPI
SpoSPBC1778.06c
GO:0051015 actin filament binding F
IDA
SceS000002536
TAS
SpoSPBC1778.06c
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPBC1778.06c
GO:0006897 endocytosis P
TAS
SceS000002536
GO:0006970 response to osmotic stress P
RCA
SceS000002536
TAS
SceS000002536
GO:0007015 actin filament organization P
IMP
SceS000002536
IPI
SceS000002536
GO:0007047 cellular cell wall organization P
RCA
SceS000002536
GO:0007121 bipolar cellular bud site selection P
TAS
SceS000002536
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPBC1778.06c
GO:0008150 biological_process P
ND
AthFIM2
At2g04750
MmuMGI:104807
GO:0008360 regulation of cell shape P
IGI
SpoSPBC1778.06c
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPBC1778.06c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002536
GO:0030437 ascospore formation P
IMP
SpoSPBC1778.06c
GO:0030835 negative regulation of actin filament
depolymerization		 P
IMP
SpoSPBC1778.06c
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPBC1778.06c
GO:0048308 organelle inheritance P
RCA
SceS000002536
GO:0051017 actin filament bundle assembly P
IMP
SpoSPBC1778.06c
GO:0051049 regulation of transport P
RCA
SceS000002536
GO:0051666 actin cortical patch localization P
IMP
SpoSPBC1778.06c
GO:0051764 actin crosslink formation P
IPI
SpoSPBC1778.06c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1428

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6579 ENSANGP00000011155
Ashbya gossypii (Ago) ago4379 AGR069C
Arabidopsis thaliana (Ath) ath7878 At2g04750.1
Arabidopsis thaliana (Ath) ath20669 At4g26700.1
Arabidopsis thaliana (Ath) ath25346 At5g35700.1
Arabidopsis thaliana (Ath) ath26745 At5g48460.1
Arabidopsis thaliana (Ath) ath27533 At5g55400.1
Caenorhabditis elegans (Cel) cel17436 Y104H12BL.1
(CE26481;
WBGene00022424)
Caenorhabditis elegans (Cel) cel17437 Y104H12BR.1
(CE27452;
WBGene00022425)
Candida glabrata (Cgl) cgl292 CAGL0B02035g
Cryptococcus neoformans (Cne) cne3925 185.m02512
Dictyostelium discoideum (Ddi) ddi12295 DDB0214994
Debaryomyces hansenii (Dha) dha4162 DEHA0E20757g
Drosophila melanogaster (Dme) dme18331 CG8649-PA
(FBgn0024238)
Drosophila melanogaster (Dme) dme18332 CG8649-PC
(FBgn0024238)
Drosophila melanogaster (Dme) dme18333 CG8649-PD
(FBgn0024238)
Danio rerio (Dre) dre10816 ENSDARP00000007231
Danio rerio (Dre) dre4849 ENSDARP00000011090
Takifugu rubripes (Fru) fru23681 SINFRUP00000137671
Takifugu rubripes (Fru) fru27485 SINFRUP00000150516
Gallus gallus (Gga) gga23139 ENSGALP00000004164
(PLS1)		 P19179
Gallus gallus (Gga) gga16806 ENSGALP00000009526
(PLS3)		 Q5ZI39
Gallus gallus (Gga) gga2953 ENSGALP00000027391
(LCP1)		 Q5ZLW0
Homo sapiens (Hsa) hsa33274 ENSP00000289290
(PLS3)		 B4DGB4
Homo sapiens (Hsa) hsa8765 ENSP00000315757
(LCP1)		 P13796
Homo sapiens (Hsa) hsa23253 ENSP00000336831
(PLS1)		 Q14651
Homo sapiens (Hsa) hsa33275 ENSP00000348163
(PLS3)		 P13797
Homo sapiens (Hsa) hsa23254 ENSP00000348922
Kluyveromyces lactis (Kla) kla4968 KLLA0F19778g
Mus musculus (Mmu) mmu8510 ENSMUSP00000022575
Mus musculus (Mmu) mmu29205 ENSMUSP00000033547
(MGI:104807)		 Q99K51
Neurospora crassa (Ncr) ncr3872 NCU03992.2
Oryza sativa (Osa) osa6622 2457.m00137
Oryza sativa (Osa) osa6995 2506.m00138
Oryza sativa (Osa) osa36038 4751.m00108
Rattus norvegicus (Rno) rno11711 ENSRNOP00000014502
(RGD:1308288)		 Q5XI38
Rattus norvegicus (Rno) rno31050 ENSRNOP00000032172
(RGD:621409)
Saccharomyces cerevisiae (Sce) sce1167 YDR129C
(S000002536)
Schizosaccharomyces pombe (Spo) spo1786 SPBC1778.06c O59945
Yarrowia lipolytica (Yli) yli1478 YALI0B17622g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g35700
At4g26700
GO:0005618 cell wall C
IDA
AthAt2g04750
GO:0005737 cytoplasm C
IDA
MmuMGI:104807
GO:0005773 vacuole C
IDA
AthAt5g55400
GO:0005826 actomyosin contractile ring C
IDA
SpoSPBC1778.06c
GO:0030479 actin cortical patch C
IDA
SceS000002536
SpoSPBC1778.06c
GO:0032420 stereocilium C
ISO
MmuMGI:104807
GO:0032432 actin filament bundle C
IDA
SceS000002536
GO:0043332 mating projection tip C
IDA
SceS000002536
GO:0003674 molecular_function F
ND
AthAt2g04750
MmuMGI:104807
GO:0003779 actin binding F
IPI
SpoSPBC1778.06c
ISS
AthAt4g26700
DmeFBgn0024238
NAS
DmeFBgn0024238
GO:0030674 protein binding, bridging F
IDA
SceS000002536
IPI
SpoSPBC1778.06c
GO:0051015 actin filament binding F
IDA
SceS000002536
TAS
SpoSPBC1778.06c
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPBC1778.06c
GO:0006897 endocytosis P
TAS
SceS000002536
GO:0006970 response to osmotic stress P
RCA
SceS000002536
TAS
SceS000002536
GO:0007015 actin filament organization P
IMP
SceS000002536
IPI
SceS000002536
GO:0007047 cellular cell wall organization P
RCA
SceS000002536
GO:0007121 bipolar cellular bud site selection P
TAS
SceS000002536
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPBC1778.06c
GO:0008150 biological_process P
ND
AthAt2g04750
At5g35700
At4g26700
At5g48460
MmuMGI:104807
GO:0008360 regulation of cell shape P
IGI
SpoSPBC1778.06c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022425
GO:0016321 female meiosis chromosome segregation P
IMP
DmeFBgn0024238
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPBC1778.06c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002536
GO:0030437 ascospore formation P
IMP
SpoSPBC1778.06c
GO:0030835 negative regulation of actin filament
depolymerization		 P
IMP
SpoSPBC1778.06c
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPBC1778.06c
GO:0048308 organelle inheritance P
RCA
SceS000002536
GO:0051017 actin filament bundle assembly P
IMP
SpoSPBC1778.06c
GO:0051049 regulation of transport P
RCA
SceS000002536
GO:0051666 actin cortical patch localization P
IMP
SpoSPBC1778.06c
GO:0051764 actin crosslink formation P
IPI
SpoSPBC1778.06c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1778.06c
(O59945)		 YDR129C
(S000002536)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005826 actomyosin contractile ring C
IDA
SpoSPBC1778.06c
GO:0030479 actin cortical patch C
IDA
SceS000002536
SpoSPBC1778.06c
GO:0032432 actin filament bundle C
IDA
SceS000002536
GO:0043332 mating projection tip C
IDA
SceS000002536
GO:0003779 actin binding F
IPI
SpoSPBC1778.06c
GO:0030674 protein binding, bridging F
IDA
SceS000002536
IPI
SpoSPBC1778.06c
GO:0051015 actin filament binding F
IDA
SceS000002536
TAS
SpoSPBC1778.06c
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPBC1778.06c
GO:0006897 endocytosis P
TAS
SceS000002536
GO:0006970 response to osmotic stress P
RCA
SceS000002536
TAS
SceS000002536
GO:0007015 actin filament organization P
IMP
SceS000002536
IPI
SceS000002536
GO:0007047 cellular cell wall organization P
RCA
SceS000002536
GO:0007121 bipolar cellular bud site selection P
TAS
SceS000002536
GO:0007163 establishment or maintenance of cell
polarity		 P
IMP
SpoSPBC1778.06c
GO:0008360 regulation of cell shape P
IGI
SpoSPBC1778.06c
GO:0030036 actin cytoskeleton organization P
IGI
SpoSPBC1778.06c
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000002536
GO:0030437 ascospore formation P
IMP
SpoSPBC1778.06c
GO:0030835 negative regulation of actin filament
depolymerization		 P
IMP
SpoSPBC1778.06c
GO:0033205 cell cycle cytokinesis P
IGI
SpoSPBC1778.06c
GO:0048308 organelle inheritance P
RCA
SceS000002536
GO:0051017 actin filament bundle assembly P
IMP
SpoSPBC1778.06c
GO:0051049 regulation of transport P
RCA
SceS000002536
GO:0051666 actin cortical patch localization P
IMP
SpoSPBC1778.06c
GO:0051764 actin crosslink formation P
IPI
SpoSPBC1778.06c

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GO info in one table:

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