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Search term: YDR142C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PEX7
SGD link S000002549
Alternative ID YDR142C
Description Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)
Synonyms YDR142C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0277 A-DHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Peroxisomal targeting signal type 2 receptor

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g29260 GI:15218882
Drosophila melanogaster (Dme) 7295052 GI:7295052 Q9VSN7
Homo sapiens (Hsa) Hs4505731
(PEX7)
GI:4505731 O00628
Saccharomyces cerevisiae (Sce) YDR142c
(S000002549)
GI:6320346 P39108
Schizosaccharomyces pombe (Spo) SPAP17D4.01 GI:19115604
Arabidopsis thaliana (Ath) At1g29260 GI:15218882
Drosophila melanogaster (Dme) 7295052 GI:7295052 Q9VSN7
Homo sapiens (Hsa) Hs4505731
(PEX7)
GI:4505731 O00628
Saccharomyces cerevisiae (Sce) YDR142c
(S000002549)
GI:6320346 P39108
Schizosaccharomyces pombe (Spo) SPAP17D4.01 GI:19115604
Arabidopsis thaliana (Ath) At1g29260 GI:15218882
Drosophila melanogaster (Dme) 7295052 GI:7295052 Q9VSN7
Homo sapiens (Hsa) Hs4505731
(PEX7)
GI:4505731 O00628
Saccharomyces cerevisiae (Sce) YDR142c
(S000002549)
GI:6320346 P39108
Schizosaccharomyces pombe (Spo) SPAP17D4.01 GI:19115604


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005777 peroxisome C
IDA
SceS000002549
GO:0005829 cytosol C
IDA
SceS000002549
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt1g29260
GO:0005053 peroxisome matrix targeting signal-2
binding
F
IDA
HsaPEX7
SceS000002549
IPI
SceS000002549
ISS
AthAt1g29260
GO:0005515 protein binding F
IPI
AthAt1g29260
GO:0006625 protein targeting to peroxisome P
IMP
AthAt1g29260
GO:0008611 ether lipid biosynthetic process P
IMP
HsaPEX7
GO:0016558 protein import into peroxisome
matrix
P
IDA
HsaPEX7
IMP
HsaPEX7
GO:0016560 protein import into peroxisome matrix,
docking
P
IPI
SceS000002549

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101567

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PEX7
(S000002549)
GI:6320346 P39108
Kluyveromyces lactis (Kla) KLLA0E03982g GI:50308255
Eremothecium gossypii (Ego) AGOS_AGL190W GI:45200907
Magnaporthe grisea (Mgr) MGG_01481 GI:39951677
Neurospora crassa (Ncr) NCU07662.1 GI:32415780


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005777 peroxisome C
IDA
SceS000002549
GO:0005829 cytosol C
IDA
SceS000002549
GO:0005053 peroxisome matrix targeting signal-2
binding
F
IDA
SceS000002549
IPI
SceS000002549
GO:0016560 protein import into peroxisome matrix,
docking
P
IPI
SceS000002549

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4204

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga1741 ENSANGP00000020634
Ashbya gossypii (Ago) ago4122 AGL190W
Arabidopsis thaliana (Ath) ath3053 At1g29260.1
Candida glabrata (Cgl) cgl270 CAGL0B01529g
Cryptococcus neoformans (Cne) cne2234 181.m08255
Dictyostelium discoideum (Ddi) ddi6499 DDB0206295
Debaryomyces hansenii (Dha) dha2879 DEHA0D13057g
Drosophila melanogaster (Dme) dme8618 CG6486-PA
(FBgn0035922)
Takifugu rubripes (Fru) fru8376 SINFRUP00000161538
Gallus gallus (Gga) gga15393 ENSGALP00000022459
(PEX7)
Gallus gallus (Gga) gga15394 ENSGALP00000022460
Gallus gallus (Gga) gga15395 ENSGALP00000022461
Homo sapiens (Hsa) hsa27804 ENSP00000230113
Homo sapiens (Hsa) hsa27803 ENSP00000315680
(PEX7)
O00628
Kluyveromyces lactis (Kla) kla3127 KLLA0E03982g
Mus musculus (Mmu) mmu1889 ENSMUSP00000020182
(MGI:1321392)
P97865
Neurospora crassa (Ncr) ncr7460 NCU07662.2
Oryza sativa (Osa) osa22386 3706.m00110
Rattus norvegicus (Rno) rno200 ENSRNOP00000016728
(RGD:1308483)
Q498S5
Saccharomyces cerevisiae (Sce) sce1180 YDR142C
(S000002549)
Schizosaccharomyces pombe (Spo) spo4723 SPAC1834.12
Yarrowia lipolytica (Yli) yli6118 YALI0F18480g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005777 peroxisome C
IDA
SceS000002549
ISS
DmeFBgn0035922
GO:0005829 cytosol C
IDA
MmuMGI:1321392
SceS000002549
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt1g29260
GO:0003674 molecular_function F
ND
MmuMGI:1321392
GO:0005053 peroxisome matrix targeting signal-2
binding
F
IDA
SceS000002549
IPI
SceS000002549
ISS
AthAt1g29260
DmeFBgn0035922
GO:0005515 protein binding F
IPI
AthAt1g29260
GO:0001764 neuron migration P
IMP
MmuMGI:1321392
GO:0001958 endochondral ossification P
IMP
MmuMGI:1321392
GO:0006625 protein targeting to peroxisome P
IMP
AthAt1g29260
MmuMGI:1321392
GO:0006635 fatty acid beta-oxidation P
IMP
MmuMGI:1321392
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0035922
GO:0007031 peroxisome organization P
ISS
DmeFBgn0035922
GO:0016558 protein import into peroxisome
matrix
P
IMP
MmuMGI:1321392
ISO
MmuMGI:1321392
GO:0016560 protein import into peroxisome matrix,
docking
P
IPI
SceS000002549

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC17D4.01
(P78798)
YDR142C
(S000002549)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC17D4.01
GO:0005777 peroxisome C
IDA
SceS000002549
GO:0005782 peroxisomal matrix C
ISS
SpoSPAC17D4.01
GO:0005829 cytosol C
IDA
SceS000002549
SpoSPAC17D4.01
ISS
SpoSPAC17D4.01
GO:0043234 protein complex C
NAS
SpoSPAC17D4.01
GO:0000268 peroxisome targeting sequence binding F
ISS
SpoSPAC17D4.01
GO:0005053 peroxisome matrix targeting signal-2
binding
F
IDA
SceS000002549
IPI
SceS000002549
GO:0006625 protein targeting to peroxisome P
ISS
SpoSPAC17D4.01
GO:0016560 protein import into peroxisome matrix,
docking
P
IPI
SceS000002549

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GO info in one table:

s.khadayate@ucl.ac.uk