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Search term: YDR168W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CDC37
SGD link S000002575
Alternative ID YDR168W
Description Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding
Synonyms YDR168W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2260 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Cell division cycle 37 protein, CDC37

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE11896 GI:17534963
Caenorhabditis elegans (Cel) CE14726
(WBGene00021097)
GI:17536793
Drosophila melanogaster (Dme) 7292159
(FBgn0011573)
GI:17136940 Q24276
Homo sapiens (Hsa) Hs20545998_1 GI:20545998
Homo sapiens (Hsa) Hs20562318_1 GI:20562318
Homo sapiens (Hsa) Hs22068999 GI:22068999
Homo sapiens (Hsa) Hs5901922
(CDC37)
GI:5901922 Q16543
Homo sapiens (Hsa) Hs8923592 GI:8923592
Saccharomyces cerevisiae (Sce) YDR168w
(S000002575)
GI:6320372 P06101
Schizosaccharomyces pombe (Spo) SPBC9B6.10 GI:19112544 O94740
Encephalitozoon cuniculi (Ecu) ECU07g0640 GI:19074486 Q8SV16


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC9B6.10
GO:0005737 cytoplasm C
IDA
DmeFBgn0011573
HsaCDC37
SceS000002575
SpoSPBC9B6.10
GO:0005829 cytosol C
IDA
SpoSPBC9B6.10
GO:0005515 protein binding F
IPI
HsaCDC37
SpoSPBC9B6.10
GO:0030296 protein tyrosine kinase activator
activity
F
NAS
DmeFBgn0011573
GO:0031072 heat shock protein binding F
IPI
HsaCDC37
SpoSPBC9B6.10
GO:0042803 protein homodimerization activity F
TAS
SpoSPBC9B6.10
GO:0051082 unfolded protein binding F
IDA
SceS000002575
ISS
DmeFBgn0011573
TAS
HsaCDC37
GO:0051087 chaperone binding F
NAS
DmeFBgn0011573
GO:0000003 reproduction P
IMP
CelWBGene00021097
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
TAS
HsaCDC37
GO:0000161 MAPKKK cascade involved in osmosensory signaling
pathway
P
IMP
SceS000002575
IPI
SceS000002575
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00021097
GO:0006457 protein folding P
IGI
SpoSPBC9B6.10
GO:0006605 protein targeting P
TAS
HsaCDC37
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00021097
GO:0007103 spindle pole body duplication in nuclear
envelope
P
IGI
SceS000002575
IMP
SceS000002575
GO:0007169 transmembrane receptor protein tyrosine kinase
signaling pathway
P
NAS
DmeFBgn0011573
GO:0007243 intracellular protein kinase cascade P
NAS
DmeFBgn0011573
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC9B6.10
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00021097
GO:0010171 body morphogenesis P
IMP
CelWBGene00021097
GO:0032872 regulation of stress-activated MAPK
cascade
P
IMP
SceS000002575
IPI
SceS000002575
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021097
GO:0040011 locomotion P
IMP
CelWBGene00021097
GO:0040015 negative regulation of multicellular organism
growth
P
IMP
CelWBGene00021097
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00021097
GO:0048518 positive regulation of biological
process
P
RCA
SceS000002575
GO:0050821 protein stabilization P
IMP
SceS000002575
GO:0051726 regulation of cell cycle P
IMP
SceS000002575
GO:0060334 regulation of interferon-gamma-mediated signaling
pathway
P
IMP
HsaCDC37
GO:0060338 regulation of type I interferon-mediated signaling
pathway
P
IMP
HsaCDC37
GO:0061077 chaperone-mediated protein folding P
NAS
SpoSPBC9B6.10
GO:0070304 positive regulation of stress-activated protein
kinase signaling cascade
P
TAS
SpoSPBC9B6.10

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38268

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CDC37 GI:5901922 Q16543
Pan troglodytes (Ptr) CDC37 GI:114675339
Canis familiaris (Cfa) CDC37 GI:73986801
Mus musculus (Mmu) Cdc37
(MGI:109531)
GI:7949018 Q61081
Rattus norvegicus (Rno) Cdc37
(RGD:71006)
GI:16758570
Drosophila melanogaster (Dme) Cdc37
(FBgn0011573)
GI:17136940 Q24276
Anopheles gambiae (Aga) AgaP_AGAP001914 GI:158301461
Caenorhabditis elegans (Cel) cdc-37
(CE14726;
WBGene00021097)
GI:115532612
Schizosaccharomyces pombe (Spo) cdc37
(SPBC9B6.10)
GI:19112544 O94740
Saccharomyces cerevisiae (Sce) CDC37
(S000002575)
GI:6320372 P06101
Kluyveromyces lactis (Kla) KLLA0D17226g GI:50307685
Eremothecium gossypii (Ego) AGOS_AGL154W GI:45200943
Magnaporthe grisea (Mgr) MGG_04990 GI:145602346
Neurospora crassa (Ncr) NCU00472.1 GI:32403890


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC9B6.10
GO:0005737 cytoplasm C
IDA
DmeFBgn0011573
HsaCDC37
SceS000002575
SpoSPBC9B6.10
GO:0005829 cytosol C
IDA
MmuMGI:109531
SpoSPBC9B6.10
GO:0005515 protein binding F
IPI
HsaCDC37
SpoSPBC9B6.10
GO:0030296 protein tyrosine kinase activator
activity
F
NAS
DmeFBgn0011573
GO:0031072 heat shock protein binding F
IPI
HsaCDC37
SpoSPBC9B6.10
GO:0042803 protein homodimerization activity F
TAS
SpoSPBC9B6.10
GO:0051082 unfolded protein binding F
IDA
SceS000002575
ISS
DmeFBgn0011573
TAS
HsaCDC37
GO:0051087 chaperone binding F
NAS
DmeFBgn0011573
GO:0051879 Hsp90 protein binding F
IDA
MmuMGI:109531
GO:0000003 reproduction P
IMP
CelWBGene00021097
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
TAS
HsaCDC37
GO:0000161 MAPKKK cascade involved in osmosensory signaling
pathway
P
IMP
SceS000002575
IPI
SceS000002575
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00021097
GO:0006457 protein folding P
IGI
SpoSPBC9B6.10
GO:0006605 protein targeting P
TAS
HsaCDC37
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00021097
GO:0007103 spindle pole body duplication in nuclear
envelope
P
IGI
SceS000002575
IMP
SceS000002575
GO:0007169 transmembrane receptor protein tyrosine kinase
signaling pathway
P
NAS
DmeFBgn0011573
GO:0007243 intracellular protein kinase cascade P
NAS
DmeFBgn0011573
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC9B6.10
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00021097
GO:0010171 body morphogenesis P
IMP
CelWBGene00021097
GO:0032872 regulation of stress-activated MAPK
cascade
P
IMP
SceS000002575
IPI
SceS000002575
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00021097
GO:0040011 locomotion P
IMP
CelWBGene00021097
GO:0040015 negative regulation of multicellular organism
growth
P
IMP
CelWBGene00021097
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00021097
GO:0048518 positive regulation of biological
process
P
RCA
SceS000002575
GO:0050821 protein stabilization P
IMP
SceS000002575
GO:0051726 regulation of cell cycle P
IMP
SceS000002575
GO:0060334 regulation of interferon-gamma-mediated signaling
pathway
P
IMP
HsaCDC37
ISO
MmuMGI:109531
GO:0060338 regulation of type I interferon-mediated signaling
pathway
P
IMP
HsaCDC37
ISO
MmuMGI:109531
GO:0061077 chaperone-mediated protein folding P
NAS
SpoSPBC9B6.10
GO:0070304 positive regulation of stress-activated protein
kinase signaling cascade
P
TAS
SpoSPBC9B6.10

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_10388

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4158 AGL154W
Candida glabrata (Cgl) cgl980 CAGL0E00913g
Cryptococcus neoformans (Cne) cne812 163.m04822
Dictyostelium discoideum (Ddi) ddi11307 DDB0183900
Debaryomyces hansenii (Dha) dha290 DEHA0A06545g
Takifugu rubripes (Fru) fru23645 SINFRUP00000154203
Kluyveromyces lactis (Kla) kla2821 KLLA0D17226g
Neurospora crassa (Ncr) ncr458 NCU00472.2
Saccharomyces cerevisiae (Sce) sce1206 YDR168W
(S000002575)
Schizosaccharomyces pombe (Spo) spo3633 SPBC9B6.10 O94740
Yarrowia lipolytica (Yli) yli4623 YALI0E18480g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC9B6.10
GO:0005737 cytoplasm C
IDA
SceS000002575
SpoSPBC9B6.10
GO:0005829 cytosol C
IDA
SpoSPBC9B6.10
GO:0005515 protein binding F
IPI
SpoSPBC9B6.10
GO:0031072 heat shock protein binding F
IPI
SpoSPBC9B6.10
GO:0042803 protein homodimerization activity F
TAS
SpoSPBC9B6.10
GO:0051082 unfolded protein binding F
IDA
SceS000002575
GO:0000161 MAPKKK cascade involved in osmosensory signaling
pathway
P
IMP
SceS000002575
IPI
SceS000002575
GO:0006457 protein folding P
IGI
SpoSPBC9B6.10
GO:0007103 spindle pole body duplication in nuclear
envelope
P
IGI
SceS000002575
IMP
SceS000002575
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC9B6.10
GO:0032872 regulation of stress-activated MAPK
cascade
P
IMP
SceS000002575
IPI
SceS000002575
GO:0048518 positive regulation of biological
process
P
RCA
SceS000002575
GO:0050821 protein stabilization P
IMP
SceS000002575
GO:0051726 regulation of cell cycle P
IMP
SceS000002575
GO:0061077 chaperone-mediated protein folding P
NAS
SpoSPBC9B6.10
GO:0070304 positive regulation of stress-activated protein
kinase signaling cascade
P
TAS
SpoSPBC9B6.10

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC9B6.10
(O94740)
YDR168W
(S000002575)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC9B6.10
GO:0005737 cytoplasm C
IDA
SceS000002575
SpoSPBC9B6.10
GO:0005829 cytosol C
IDA
SpoSPBC9B6.10
GO:0005515 protein binding F
IPI
SpoSPBC9B6.10
GO:0031072 heat shock protein binding F
IPI
SpoSPBC9B6.10
GO:0042803 protein homodimerization activity F
TAS
SpoSPBC9B6.10
GO:0051082 unfolded protein binding F
IDA
SceS000002575
GO:0000161 MAPKKK cascade involved in osmosensory signaling
pathway
P
IMP
SceS000002575
IPI
SceS000002575
GO:0006457 protein folding P
IGI
SpoSPBC9B6.10
GO:0007103 spindle pole body duplication in nuclear
envelope
P
IGI
SceS000002575
IMP
SceS000002575
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC9B6.10
GO:0032872 regulation of stress-activated MAPK
cascade
P
IMP
SceS000002575
IPI
SceS000002575
GO:0048518 positive regulation of biological
process
P
RCA
SceS000002575
GO:0050821 protein stabilization P
IMP
SceS000002575
GO:0051726 regulation of cell cycle P
IMP
SceS000002575
GO:0061077 chaperone-mediated protein folding P
NAS
SpoSPBC9B6.10
GO:0070304 positive regulation of stress-activated protein
kinase signaling cascade
P
TAS
SpoSPBC9B6.10

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk