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Search term: YDR177W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UBC1
SGD link S000002584
Alternative ID YDR177W
Description Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response
Synonyms YDR177W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0418 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin-protein ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g50870 GI:15241303
Caenorhabditis elegans (Cel) CE03946 GI:17550202
Caenorhabditis elegans (Cel) CE03948 GI:17550206
Caenorhabditis elegans (Cel) CE04118_2 GI:17550674
Caenorhabditis elegans (Cel) CE19850
(WBGene00006715)
GI:17553340 Q9TZ69
Drosophila melanogaster (Dme) 7294892 GI:1850816
Homo sapiens (Hsa) Hs4885417
(UBE2K)
GI:4885417 Q9Y2D3
Saccharomyces cerevisiae (Sce) YDR177w
(S000002584)
GI:6320382 P21734
Schizosaccharomyces pombe (Spo) SPBC2D10.20 GI:19113031 O74810
Arabidopsis thaliana (Ath) At5g50870 GI:15241303
Caenorhabditis elegans (Cel) CE03946 GI:17550202
Caenorhabditis elegans (Cel) CE03948 GI:17550206
Caenorhabditis elegans (Cel) CE04118_2 GI:17550674
Caenorhabditis elegans (Cel) CE19850
(WBGene00006715)
GI:17553340 Q9TZ69
Drosophila melanogaster (Dme) 7294892 GI:1850816
Homo sapiens (Hsa) Hs4885417
(UBE2K)
GI:4885417 Q9Y2D3
Saccharomyces cerevisiae (Sce) YDR177w
(S000002584)
GI:6320382 P21734
Schizosaccharomyces pombe (Spo) SPBC2D10.20 GI:19113031 O74810
Arabidopsis thaliana (Ath) At5g50870 GI:15241303
Caenorhabditis elegans (Cel) CE03946 GI:17550202
Caenorhabditis elegans (Cel) CE03948 GI:17550206
Caenorhabditis elegans (Cel) CE04118_2 GI:17550674
Caenorhabditis elegans (Cel) CE19850
(WBGene00006715)
GI:17553340 Q9TZ69
Drosophila melanogaster (Dme) 7294892 GI:1850816
Homo sapiens (Hsa) Hs4885417
(UBE2K)
GI:4885417 Q9Y2D3
Saccharomyces cerevisiae (Sce) YDR177w
(S000002584)
GI:6320382 P21734
Schizosaccharomyces pombe (Spo) SPBC2D10.20 GI:19113031 O74810


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002584
GO:0005575 cellular_component C
ND
AthAt5g50870
GO:0005634 nucleus C
IDA
SpoSPBC2D10.20
GO:0005829 cytosol C
IDA
SpoSPBC2D10.20
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthAt5g50870
HsaUBE2K
SceS000002584
ISS
AthAt5g50870
SceS000002584
GO:0005515 protein binding F
IPI
HsaUBE2K
GO:0031625 ubiquitin protein ligase binding F
IPI
HsaUBE2K
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
HsaUBE2K
GO:0000209 protein polyubiquitination P
TAS
SceS000002584
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IDA
AthAt5g50870
TAS
HsaUBE2K
GO:0006513 protein monoubiquitination P
TAS
SceS000002584
GO:0006897 endocytosis P
TAS
SceS000002584
GO:0009847 spore germination P
TAS
SceS000002584
GO:0016050 vesicle organization P
IMP
SceS000002584
GO:0016567 protein ubiquitination P
ISS
SpoSPBC2D10.20
GO:0030433 ER-associated protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0070936 protein K48-linked ubiquitination P
IDA
HsaUBE2K

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3903

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) UBE2K GI:4885417 Q9Y2D3
Pan troglodytes (Ptr) UBE2K GI:55622402
Canis familiaris (Cfa) UBE2K GI:73951540
Mus musculus (Mmu) Ube2k
(MGI:1858216)
GI:31542956 P61087
Rattus norvegicus (Rno) Ube2k GI:27695307
Gallus gallus (Gga) HIP2 GI:71895881
Drosophila melanogaster (Dme) UbcD4
(FBgn0015321)
GI:24661830
Anopheles gambiae (Aga) AgaP_AGAP004889 GI:158292979
Caenorhabditis elegans (Cel) ubc-20
(CE19850;
WBGene00006715)
GI:17553340 Q9TZ69
Caenorhabditis elegans (Cel) ubc-21
(CE40013;
WBGene00006716)
GI:115535047
Schizosaccharomyces pombe (Spo) ubc1
(SPBC2D10.20)
GI:19113031 O74810
Saccharomyces cerevisiae (Sce) UBC1
(S000002584)
GI:6320382 P21734
Kluyveromyces lactis (Kla) KLLA0C18656g GI:50306139
Eremothecium gossypii (Ego) AGOS_ADR169C GI:45188043
Magnaporthe grisea (Mgr) MGG_05478 GI:39941132
Neurospora crassa (Ncr) NCU01225.1 GI:32412476
Arabidopsis thaliana (Ath) UBC27 GI:15241303
Oryza sativa (Osa) Os01g0925800 GI:115441959
Plasmodium falciparum (Pfa) PF13_0301 GI:124513836


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002584
GO:0005575 cellular_component C
ND
AthUBC27
MmuMGI:1858216
GO:0005634 nucleus C
IDA
SpoSPBC2D10.20
GO:0005829 cytosol C
IDA
SpoSPBC2D10.20
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthUBC27
HsaUBE2K
SceS000002584
ISS
AthUBC27
SceS000002584
NAS
DmeFBgn0015321
TAS
MmuMGI:1858216
GO:0005515 protein binding F
IPI
HsaUBE2K
GO:0031625 ubiquitin protein ligase binding F
IPI
HsaUBE2K
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
HsaUBE2K
GO:0000209 protein polyubiquitination P
TAS
SceS000002584
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IDA
AthUBC27
ISS
PfaPF13_0301
TAS
HsaUBE2K
GO:0006513 protein monoubiquitination P
TAS
SceS000002584
GO:0006897 endocytosis P
TAS
SceS000002584
GO:0009847 spore germination P
TAS
SceS000002584
GO:0016050 vesicle organization P
IMP
SceS000002584
GO:0016567 protein ubiquitination P
ISS
SpoSPBC2D10.20
TAS
MmuMGI:1858216
GO:0030433 ER-associated protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0070936 protein K48-linked ubiquitination P
IDA
HsaUBE2K

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2550

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga241 ENSANGP00000023498
Ashbya gossypii (Ago) ago1911 ADR169C
Arabidopsis thaliana (Ath) ath27021 At5g50870.1
Caenorhabditis elegans (Cel) cel8713 F40G9.3
(CE19850;
WBGene00006715)
Candida glabrata (Cgl) cgl970 CAGL0E00671g
Cryptococcus neoformans (Cne) cne5583 179.m00443
Debaryomyces hansenii (Dha) dha3336 DEHA0E02134g
Drosophila melanogaster (Dme) dme8820 CG8284-PA
(FBgn0015321)
Danio rerio (Dre) dre498 ENSDARP00000018676
(hip2)
Q5PR60
Takifugu rubripes (Fru) fru6495 SINFRUP00000142439
Takifugu rubripes (Fru) fru26755 SINFRUP00000160850
Gallus gallus (Gga) gga18185 ENSGALP00000023065
(HIP2)
Homo sapiens (Hsa) hsa24032 ENSP00000261427
(UBE2K)
P61086-1
Kluyveromyces lactis (Kla) kla2030 KLLA0C18656g
Mus musculus (Mmu) mmu20149 ENSMUSP00000031105
(MGI:1858216)
P61087
Neurospora crassa (Ncr) ncr1188 NCU01225.2
Oryza sativa (Osa) osa32046 4445.m00112
Oryza sativa (Osa) osa33959 4658.m00117
Plasmodium falciparum (Pfa) pfa3817 PF13_0301
Rattus norvegicus (Rno) rno10375 ENSRNOP00000032265
(RGD:1311626)
Saccharomyces cerevisiae (Sce) sce1217 YDR177W
(S000002584)
Schizosaccharomyces pombe (Spo) spo670 SPBC2D10.20 O74810
Yarrowia lipolytica (Yli) yli5443 YALI0F02563g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002584
GO:0005575 cellular_component C
ND
AthAt5g50870
MmuMGI:1858216
GO:0005634 nucleus C
IDA
SpoSPBC2D10.20
GO:0005829 cytosol C
IDA
SpoSPBC2D10.20
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthAt5g50870
SceS000002584
ISS
AthAt5g50870
SceS000002584
NAS
DmeFBgn0015321
TAS
MmuMGI:1858216
GO:0000209 protein polyubiquitination P
TAS
SceS000002584
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IDA
AthAt5g50870
ISS
PfaPF13_0301
GO:0006513 protein monoubiquitination P
TAS
SceS000002584
GO:0006897 endocytosis P
TAS
SceS000002584
GO:0009847 spore germination P
TAS
SceS000002584
GO:0016050 vesicle organization P
IMP
SceS000002584
GO:0016567 protein ubiquitination P
ISS
SpoSPBC2D10.20
TAS
MmuMGI:1858216
GO:0030433 ER-associated protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC2D10.20
(O74810)
YDR177W
(S000002584)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
IPI
SceS000002584
GO:0005634 nucleus C
IDA
SpoSPBC2D10.20
GO:0005829 cytosol C
IDA
SpoSPBC2D10.20
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002584
ISS
SceS000002584
GO:0000209 protein polyubiquitination P
TAS
SceS000002584
GO:0006513 protein monoubiquitination P
TAS
SceS000002584
GO:0006897 endocytosis P
TAS
SceS000002584
GO:0009847 spore germination P
TAS
SceS000002584
GO:0016050 vesicle organization P
IMP
SceS000002584
GO:0016567 protein ubiquitination P
ISS
SpoSPBC2D10.20
GO:0030433 ER-associated protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process
P
IGI
SceS000002584
IMP
SceS000002584

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GO info in one table:

s.khadayate@ucl.ac.uk