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Search term: YDR178W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SDH4
SGD link S000002585
Alternative ID YDR178W
Description Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
Synonyms YDR178W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4097 -CDHYP-

KOGs classification KOGs description
METABOLISMCELLULAR PROCESSES AND SIGNALING Succinate dehydrogenase membrane anchor subunit and related proteins

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE17757
(WBGene00009353)		 GI:17533639 O62215
Drosophila melanogaster (Dme) 7301044 GI:7301044
Homo sapiens (Hsa) Hs22043268 GI:22043268
Homo sapiens (Hsa) Hs4506865
(SDHD)		 GI:4506865 O14521
Saccharomyces cerevisiae (Sce) YDR178w
(S000002585)		 GI:6320383 P37298
Saccharomyces cerevisiae (Sce) YLR164w GI:6323193 Q06236
Saccharomyces cerevisiae (Sce) YOR297c
(S000005823)		 GI:6324871 Q08749
Schizosaccharomyces pombe (Spo) SPBP23A10.16 GI:19112620 Q9P7X0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceYLR164w
S000002585
S000005823
SpoSPBP23A10.16
GO:0005743 mitochondrial inner membrane C
EXP
HsaSDHD
IDA
HsaSDHD
SceYLR164w
ISS
HsaSDHD
GO:0005749 mitochondrial respiratory chain complex
II		 C
ISS
HsaSDHD
SpoSPBP23A10.16
TAS
SceS000002585
GO:0016021 integral to membrane C
ISS
SpoSPBP23A10.16
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
IDA
SceS000005823
ISS
SpoSPBP23A10.16
GO:0000104 succinate dehydrogenase activity F
IDA
HsaSDHD
GO:0003674 molecular_function F
ND
SceYLR164w
GO:0008177 succinate dehydrogenase (ubiquinone)
activity		 F
IGI
SceS000002585
GO:0009055 electron carrier activity F
TAS
HsaSDHD
GO:0015266 protein channel activity F
IDA
SceS000005823
GO:0020037 heme binding F
ISS
HsaSDHD
SpoSPBP23A10.16
GO:0043495 protein anchor F
NAS
SpoSPBP23A10.16
GO:0048039 ubiquinone binding F
ISS
HsaSDHD
SpoSPBP23A10.16
GO:0001101 response to acid P
IMP
SceS000005823
GO:0002119 nematode larval development P
IMP
CelWBGene00009353
GO:0006099 tricarboxylic acid cycle P
IDA
HsaSDHD
TAS
SceS000002585
GO:0006121 mitochondrial electron transport, succinate to
ubiquinone		 P
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0006793 phosphorus metabolic process P
RCA
SceS000002585
GO:0006811 ion transport P
RCA
SceS000002585
GO:0006915 apoptosis P
IMP
SceS000005823
GO:0006970 response to osmotic stress P
IMP
SceS000005823
GO:0008150 biological_process P
ND
SceYLR164w
GO:0008219 cell death P
RCA
SceS000002585
GO:0009117 nucleotide metabolic process P
RCA
SceS000002585
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009353
GO:0034599 cellular response to oxidative
stress		 P
IMP
SceS000005823
GO:0040007 growth P
IMP
CelWBGene00009353
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009353
GO:0045039 protein import into mitochondrial inner
membrane		 P
IGI
SceS000005823
ISS
SpoSPBP23A10.16
GO:0045333 cellular respiration P
IMP
SceS000002585
GO:0046685 response to arsenic P
IMP
SceS000005823
GO:0051186 cofactor metabolic process P
RCA
SceS000002585
GO:0055114 oxidation reduction P
RCA
SceS000002585

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68839

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) sdh4
(SPBP23A10.16)		 GI:19112620 Q9P7X0
Saccharomyces cerevisiae (Sce) SDH4
(S000002585)		 GI:6320383 P37298
Saccharomyces cerevisiae (Sce) YLR164W GI:6323193 Q06236
Kluyveromyces lactis (Kla) KLLA0D18117g GI:50307737
Eremothecium gossypii (Ego) AGOS_AGL137W GI:45200960
Magnaporthe grisea (Mgr) MGG_00666 GI:39974375
Neurospora crassa (Ncr) NCU03031.1 GI:32419549


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceYLR164w
S000002585
SpoSPBP23A10.16
GO:0005743 mitochondrial inner membrane C
IDA
SceYLR164w
GO:0005749 mitochondrial respiratory chain complex
II		 C
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0016021 integral to membrane C
ISS
SpoSPBP23A10.16
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
ISS
SpoSPBP23A10.16
GO:0003674 molecular_function F
ND
SceYLR164w
GO:0008177 succinate dehydrogenase (ubiquinone)
activity		 F
IGI
SceS000002585
GO:0020037 heme binding F
ISS
SpoSPBP23A10.16
GO:0043495 protein anchor F
NAS
SpoSPBP23A10.16
GO:0048039 ubiquinone binding F
ISS
SpoSPBP23A10.16
GO:0006099 tricarboxylic acid cycle P
TAS
SceS000002585
GO:0006121 mitochondrial electron transport, succinate to
ubiquinone		 P
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0006793 phosphorus metabolic process P
RCA
SceS000002585
GO:0006811 ion transport P
RCA
SceS000002585
GO:0008150 biological_process P
ND
SceYLR164w
GO:0008219 cell death P
RCA
SceS000002585
GO:0009117 nucleotide metabolic process P
RCA
SceS000002585
GO:0045039 protein import into mitochondrial inner
membrane		 P
ISS
SpoSPBP23A10.16
GO:0045333 cellular respiration P
IMP
SceS000002585
GO:0051186 cofactor metabolic process P
RCA
SceS000002585
GO:0055114 oxidation reduction P
RCA
SceS000002585

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4626

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15261 ENSANGP00000019261
Ashbya gossypii (Ago) ago3715 AFR523C
Ashbya gossypii (Ago) ago4175 AGL137W
Caenorhabditis elegans (Cel) cel7964 F33A8.5
(CE17757;
WBGene00009353)
Candida glabrata (Cgl) cgl158 CAGL0A03784g
Candida glabrata (Cgl) cgl1484 CAGL0F05863g
Cryptococcus neoformans (Cne) cne4649 186.m03493
Debaryomyces hansenii (Dha) dha2982 DEHA0D15246g
Debaryomyces hansenii (Dha) dha6460 DEHA0G16984g
Drosophila melanogaster (Dme) dme14069 CG10219-PA
(FBgn0039112)
Gallus gallus (Gga) gga13335 ENSGALP00000012780
(SDHD)		 Q5ZIS0
Kluyveromyces lactis (Kla) kla2861 KLLA0D18117g
Kluyveromyces lactis (Kla) kla5198 KLLA0F25080g
Mus musculus (Mmu) mmu27595 ENSMUSP00000000175
(MGI:1914175)		 Q9CXV1
Neurospora crassa (Ncr) ncr2936 NCU03031.2
Rattus norvegicus (Rno) rno28571 ENSRNOP00000034407
(RGD:735231)
Saccharomyces cerevisiae (Sce) sce1218 YDR178W
(S000002585)
Saccharomyces cerevisiae (Sce) sce4264 YLR164W
Saccharomyces cerevisiae (Sce) sce6044 YOR297C
(S000005823)
Schizosaccharomyces pombe (Spo) spo2442 SPBP23A10.16 Q9P7X0
Yarrowia lipolytica (Yli) yli479 YALI0A14784g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1914175
SceYLR164w
S000002585
S000005823
SpoSPBP23A10.16
GO:0005743 mitochondrial inner membrane C
IDA
SceYLR164w
ISS
DmeFBgn0039112
GO:0005749 mitochondrial respiratory chain complex
II		 C
ISS
DmeFBgn0039112
SpoSPBP23A10.16
TAS
SceS000002585
GO:0016021 integral to membrane C
ISS
SpoSPBP23A10.16
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
IDA
SceS000005823
ISS
SpoSPBP23A10.16
GO:0000104 succinate dehydrogenase activity F
ISS
DmeFBgn0039112
GO:0003674 molecular_function F
ND
SceYLR164w
GO:0008177 succinate dehydrogenase (ubiquinone)
activity		 F
IGI
SceS000002585
ISS
DmeFBgn0039112
GO:0015266 protein channel activity F
IDA
SceS000005823
GO:0020037 heme binding F
ISS
SpoSPBP23A10.16
GO:0043495 protein anchor F
NAS
SpoSPBP23A10.16
GO:0048039 ubiquinone binding F
ISS
SpoSPBP23A10.16
GO:0001101 response to acid P
IMP
SceS000005823
GO:0002119 nematode larval development P
IMP
CelWBGene00009353
GO:0006099 tricarboxylic acid cycle P
ISS
DmeFBgn0039112
TAS
SceS000002585
GO:0006121 mitochondrial electron transport, succinate to
ubiquinone		 P
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0006793 phosphorus metabolic process P
RCA
SceS000002585
GO:0006811 ion transport P
RCA
SceS000002585
GO:0006915 apoptosis P
IMP
SceS000005823
GO:0006970 response to osmotic stress P
IMP
SceS000005823
GO:0008150 biological_process P
ND
SceYLR164w
GO:0008219 cell death P
RCA
SceS000002585
GO:0009117 nucleotide metabolic process P
RCA
SceS000002585
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009353
GO:0034599 cellular response to oxidative
stress		 P
IMP
SceS000005823
GO:0040007 growth P
IMP
CelWBGene00009353
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009353
GO:0045039 protein import into mitochondrial inner
membrane		 P
IGI
SceS000005823
ISS
SpoSPBP23A10.16
GO:0045333 cellular respiration P
IMP
SceS000002585
GO:0046685 response to arsenic P
IMP
SceS000005823
GO:0051186 cofactor metabolic process P
RCA
SceS000002585
GO:0055114 oxidation reduction P
RCA
SceS000002585

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP23A10.16
(Q9P7X0)		 YDR178W
(S000002585)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000002585
SpoSPBP23A10.16
GO:0005749 mitochondrial respiratory chain complex
II		 C
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0016021 integral to membrane C
ISS
SpoSPBP23A10.16
GO:0042721 mitochondrial inner membrane protein insertion
complex		 C
ISS
SpoSPBP23A10.16
GO:0008177 succinate dehydrogenase (ubiquinone)
activity		 F
IGI
SceS000002585
GO:0020037 heme binding F
ISS
SpoSPBP23A10.16
GO:0043495 protein anchor F
NAS
SpoSPBP23A10.16
GO:0048039 ubiquinone binding F
ISS
SpoSPBP23A10.16
GO:0006099 tricarboxylic acid cycle P
TAS
SceS000002585
GO:0006121 mitochondrial electron transport, succinate to
ubiquinone		 P
ISS
SpoSPBP23A10.16
TAS
SceS000002585
GO:0006793 phosphorus metabolic process P
RCA
SceS000002585
GO:0006811 ion transport P
RCA
SceS000002585
GO:0008219 cell death P
RCA
SceS000002585
GO:0009117 nucleotide metabolic process P
RCA
SceS000002585
GO:0045039 protein import into mitochondrial inner
membrane		 P
ISS
SpoSPBP23A10.16
GO:0045333 cellular respiration P
IMP
SceS000002585
GO:0051186 cofactor metabolic process P
RCA
SceS000002585
GO:0055114 oxidation reduction P
RCA
SceS000002585

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk