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Search term: YDR180W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SCC2
SGD link S000002588
Alternative ID YDR180W
Description Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin
Synonyms YDR180W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1020 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGCELLULAR PROCESSES AND SIGNALINGINFORMATION STORAGE AND PROCESSING Sister chromatid cohesion protein SCC2/Nipped-B

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g15540 GI:15242325
Caenorhabditis elegans (Cel) CE27255 GI:17537109
Drosophila melanogaster (Dme) 7289131 GI:7289131
Homo sapiens (Hsa) Hs7661842 GI:7661842
Homo sapiens (Hsa) Hs19718749 GI:19718749
Saccharomyces cerevisiae (Sce) YDR180w
(S000002588)		 GI:6320386 Q04002
Schizosaccharomyces pombe (Spo) SPAC31A2.05c GI:19113829 Q09725
Arabidopsis thaliana (Ath) At5g15540 GI:15242325
Caenorhabditis elegans (Cel) CE27255 GI:17537109
Drosophila melanogaster (Dme) 7289131 GI:7289131
Homo sapiens (Hsa) Hs7661842 GI:7661842
Homo sapiens (Hsa) Hs19718749 GI:19718749
Saccharomyces cerevisiae (Sce) YDR180w
(S000002588)		 GI:6320386 Q04002
Schizosaccharomyces pombe (Spo) SPAC31A2.05c GI:19113829 Q09725


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000002588
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC31A2.05c
GO:0005634 nucleus C
IC
SpoSPAC31A2.05c
IDA
SpoSPAC31A2.05c
GO:0005694 chromosome C
IDA
SpoSPAC31A2.05c
GO:0005729 2-micrometer circle DNA C
IDA
SceS000002588
GO:0005829 cytosol C
IDA
SpoSPAC31A2.05c
GO:0030892 mitotic cohesin complex C
IDA
SpoSPAC31A2.05c
GO:0032116 cohesin loading complex C
IMP
SpoSPAC31A2.05c
IPI
SceS000002588
GO:0003674 molecular_function F
ND
SceS000002588
GO:0005515 protein binding F
IPI
SpoSPAC31A2.05c
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPAC31A2.05c
GO:0000972 transcription-dependent tethering of RNA
polymerase II gene DNA at nuclear
periphery		 P
IMP
SceS000002588
GO:0006302 double-strand break repair P
IMP
SceS000002588
GO:0007052 mitotic spindle organization P
IMP
SpoSPAC31A2.05c
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC31A2.05c
IMP
AthAt5g15540
GO:0007064 mitotic sister chromatid cohesion P
IMP
SpoSPAC31A2.05c
GO:0007076 mitotic chromosome condensation P
IMP
SceS000002588
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
IMP
SpoSPAC31A2.05c
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g15540
GO:0030543 2-micrometer plasmid partitioning P
IC
SceS000002588
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002588
GO:0034184 positive regulation of maintenance of mitotic
sister chromatid cohesion		 P
IMP
SpoSPAC31A2.05c
GO:0034508 centromere complex assembly P
IMP
AthAt5g15540
GO:0051177 meiotic sister chromatid cohesion P
IMP
AthAt5g15540
GO:0070058 tRNA gene clustering P
IMP
SceS000002588
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC31A2.05c
GO:0070550 rDNA condensation P
IMP
SceS000002588
GO:0071168 protein localization to chromatin P
IMP
SceS000002588
GO:0071169 establishment of protein localization to
chromatin		 P
IMP
SceS000002588

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117771

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SCC2
(S000002588)		 GI:6320386 Q04002
Kluyveromyces lactis (Kla) KLLA0D18194g GI:50307745
Eremothecium gossypii (Ego) AGOS_AGL133W GI:45200964


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000002588
GO:0005729 2-micrometer circle DNA C
IDA
SceS000002588
GO:0032116 cohesin loading complex C
IPI
SceS000002588
GO:0003674 molecular_function F
ND
SceS000002588
GO:0000972 transcription-dependent tethering of RNA
polymerase II gene DNA at nuclear
periphery		 P
IMP
SceS000002588
GO:0006302 double-strand break repair P
IMP
SceS000002588
GO:0007076 mitotic chromosome condensation P
IMP
SceS000002588
GO:0030543 2-micrometer plasmid partitioning P
IC
SceS000002588
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002588
GO:0070058 tRNA gene clustering P
IMP
SceS000002588
GO:0070550 rDNA condensation P
IMP
SceS000002588
GO:0071168 protein localization to chromatin P
IMP
SceS000002588
GO:0071169 establishment of protein localization to
chromatin		 P
IMP
SceS000002588

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1959

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11443 ENSANGP00000010656
Anopheles gambiae (Aga) aga11442 ENSANGP00000028248
Ashbya gossypii (Ago) ago4179 AGL133W
Arabidopsis thaliana (Ath) ath23767 At5g15540.1
Caenorhabditis elegans (Cel) cel18865 Y43H11AL.3
(CE36034;
WBGene00004166)
Candida glabrata (Cgl) cgl1481 CAGL0F05797g
Cryptococcus neoformans (Cne) cne2263 181.m08286
Dictyostelium discoideum (Ddi) ddi6163 DDB0185354
Debaryomyces hansenii (Dha) dha6463 DEHA0G17050g
Debaryomyces hansenii (Dha) dha6464 DEHA0G17072g
Drosophila melanogaster (Dme) dme15665 CG17704-PE
Drosophila melanogaster (Dme) dme15666 CG17704-PF
Danio rerio (Dre) dre4760 ENSDARP00000020847
Danio rerio (Dre) dre4761 ENSDARP00000029994
Danio rerio (Dre) dre2075 ENSDARP00000036295
Danio rerio (Dre) dre2089 ENSDARP00000038402
Danio rerio (Dre) dre31303 ENSDARP00000049537
Takifugu rubripes (Fru) fru9339 SINFRUP00000132705
Takifugu rubripes (Fru) fru9340 SINFRUP00000132715
Takifugu rubripes (Fru) fru9341 SINFRUP00000170724
Takifugu rubripes (Fru) fru11437 SINFRUP00000176488
Gallus gallus (Gga) gga28324 ENSGALP00000005697
Gallus gallus (Gga) gga26369 ENSGALP00000021707
(LOC426031)
Gallus gallus (Gga) gga27484 ENSGALP00000023680
Homo sapiens (Hsa) hsa25141 ENSP00000282516
(NIPBL)		 Q6KC79-1
Homo sapiens (Hsa) hsa25140 ENSP00000349476
Kluyveromyces lactis (Kla) kla2865 KLLA0D18194g
Mus musculus (Mmu) mmu8745 ENSMUSP00000059385
(MGI:1913976)		 Q6KCD5-1
Neurospora crassa (Ncr) ncr5095 NCU05250.2
Oryza sativa (Osa) osa45253 5640.m00102
Rattus norvegicus (Rno) rno15621 ENSRNOP00000020954
(RGD:1306393)
Saccharomyces cerevisiae (Sce) sce1221 YDR180W
(S000002588)
Schizosaccharomyces pombe (Spo) spo1778 SPAC31A2.05c Q09725
Yarrowia lipolytica (Yli) yli475 YALI0A14707g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000002588
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC31A2.05c
GO:0005575 cellular_component C
ND
MmuMGI:1913976
GO:0005634 nucleus C
IC
SpoSPAC31A2.05c
IDA
SpoSPAC31A2.05c
GO:0005694 chromosome C
IDA
SpoSPAC31A2.05c
GO:0005729 2-micrometer circle DNA C
IDA
SceS000002588
GO:0005829 cytosol C
IDA
SpoSPAC31A2.05c
GO:0030892 mitotic cohesin complex C
IDA
SpoSPAC31A2.05c
GO:0032116 cohesin loading complex C
IMP
SpoSPAC31A2.05c
IPI
SceS000002588
GO:0003674 molecular_function F
ND
MmuMGI:1913976
SceS000002588
GO:0005515 protein binding F
IPI
SpoSPAC31A2.05c
GO:0000003 reproduction P
IMP
CelWBGene00004166
GO:0000070 mitotic sister chromatid segregation P
IGI
CelWBGene00004166
IMP
CelWBGene00004166
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPAC31A2.05c
GO:0000972 transcription-dependent tethering of RNA
polymerase II gene DNA at nuclear
periphery		 P
IMP
SceS000002588
GO:0006302 double-strand break repair P
IMP
SceS000002588
GO:0007052 mitotic spindle organization P
IMP
SpoSPAC31A2.05c
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC31A2.05c
IMP
AthAt5g15540
GO:0007064 mitotic sister chromatid cohesion P
IMP
SpoSPAC31A2.05c
GO:0007076 mitotic chromosome condensation P
IMP
SceS000002588
GO:0007507 heart development P
IMP
MmuMGI:1913976
GO:0008608 attachment of spindle microtubules to
kinetochore		 P
IMP
SpoSPAC31A2.05c
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004166
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g15540
GO:0010171 body morphogenesis P
IMP
CelWBGene00004166
GO:0030543 2-micrometer plasmid partitioning P
IC
SceS000002588
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002588
GO:0034184 positive regulation of maintenance of mitotic
sister chromatid cohesion		 P
IMP
SpoSPAC31A2.05c
GO:0034508 centromere complex assembly P
IMP
AthAt5g15540
GO:0040011 locomotion P
IMP
CelWBGene00004166
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
MmuMGI:1913976
GO:0045444 fat cell differentiation P
IMP
MmuMGI:1913976
GO:0045778 positive regulation of ossification P
IMP
MmuMGI:1913976
GO:0048701 embryonic cranial skeleton morphogenesis P
IMP
MmuMGI:1913976
GO:0048703 embryonic viscerocranium morphogenesis P
IMP
MmuMGI:1913976
GO:0051177 meiotic sister chromatid cohesion P
IMP
AthAt5g15540
GO:0070058 tRNA gene clustering P
IMP
SceS000002588
GO:0070317 negative regulation of G0 to G1
transition		 P
IMP
SpoSPAC31A2.05c
GO:0070550 rDNA condensation P
IMP
SceS000002588
GO:0071168 protein localization to chromatin P
IMP
SceS000002588
GO:0071169 establishment of protein localization to
chromatin		 P
IMP
SceS000002588

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC31A2.05c
(Q09725)		 YDR180W
(S000002588)