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Search term: YDR196C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CAB5
SGD link S000002604
Alternative ID YDR196C
Description Probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies
Synonyms YDR196C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3220 ACDHYPE

KOGs classification KOGs description
METABOLISM Similar to bacterial dephospho-CoA kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g27490 GI:15225886
Caenorhabditis elegans (Cel) CE23950
(WBGene00011500)		 GI:17554944 P34558
Caenorhabditis elegans (Cel) CE28145_2 GI:17510389
Drosophila melanogaster (Dme) 7298862 GI:7298862 Q9VI57
Homo sapiens (Hsa) Hs19923601 GI:19923601
Homo sapiens (Hsa) Hs21489977_2 GI:17981025 Q13057
Homo sapiens (Hsa) Hs22063771 GI:22063771
Homo sapiens (Hsa) HsM13376838_2 GI:13376838
Saccharomyces cerevisiae (Sce) YDR196c
(S000002604)		 GI:6320402 Q03941
Schizosaccharomyces pombe (Spo) SPCC14G10.01 GI:19075442 O74414
Encephalitozoon cuniculi (Ecu) ECU11g0300 GI:19074830 Q8SU80


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005635 nuclear envelope C
IDA
SceS000002604
GO:0005737 cytoplasm C
IDA
SpoSPCC14G10.01
GO:0005739 mitochondrion C
IDA
SceS000002604
GO:0005773 vacuole C
IDA
AthAt2g27490
GO:0005777 peroxisome C
IDA
AthAt2g27490
GO:0005783 endoplasmic reticulum C
IDA
SceS000002604
ISS
SpoSPCC14G10.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPCC14G10.01
GO:0009507 chloroplast C
IDA
AthAt2g27490
GO:0031965 nuclear membrane C
ISS
SpoSPCC14G10.01
GO:0004140 dephospho-CoA kinase activity F
IDA
AthAt2g27490
ISS
AthAt2g27490
SceS000002604
SpoSPCC14G10.01
GO:0005524 ATP binding F
ISS
AthAt2g27490
SpoSPCC14G10.01
GO:0015937 coenzyme A biosynthetic process P
IDA
AthAt2g27490
IGI
SceS000002604
ISS
AthAt2g27490
SceS000002604
SpoSPCC14G10.01

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5652

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DCAKD GI:191252797
Pan troglodytes (Ptr) DCAKD GI:114666727
Canis familiaris (Cfa) DCAKD GI:73965494
Mus musculus (Mmu) Dcakd
(MGI:1915337)		 GI:27754054 Q6PDP7
Rattus norvegicus (Rno) Dcakd
(RGD:1359211)		 GI:56090393
Gallus gallus (Gga) DCAKD GI:118102803
Drosophila melanogaster (Dme) CG1939
(FBgn0037469)		 GI:24644728
Anopheles gambiae (Aga) AgaP_AGAP004425 GI:118784403
Caenorhabditis elegans (Cel) T05G5.5
(CE23950;
WBGene00011500)		 GI:17554944 P34558
Schizosaccharomyces pombe (Spo) SPCC14G10.01 GI:19075442 O74414
Saccharomyces cerevisiae (Sce) YDR196C
(S000002604)		 GI:6320402 Q03941
Kluyveromyces lactis (Kla) KLLA0D18711g GI:50307793
Eremothecium gossypii (Ego) AGOS_AGL110C GI:45200987
Magnaporthe grisea (Mgr) MGG_11322 GI:145614236
Neurospora crassa (Ncr) NCU00369.1 GI:32403684
Arabidopsis thaliana (Ath) ATCOAE GI:30683542
Oryza sativa (Osa) Os01g0360600 GI:115436526
Plasmodium falciparum (Pfa) PF14_0415 GI:124809497


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005635 nuclear envelope C
IDA
SceS000002604
GO:0005737 cytoplasm C
IDA
SpoSPCC14G10.01
GO:0005739 mitochondrion C
IDA
MmuMGI:1915337
SceS000002604
GO:0005773 vacuole C
IDA
AthATCOAE
GO:0005777 peroxisome C
IDA
AthATCOAE
GO:0005783 endoplasmic reticulum C
IDA
SceS000002604
ISS
SpoSPCC14G10.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPCC14G10.01
GO:0009507 chloroplast C
IDA
AthATCOAE
GO:0020011 apicoplast C
ISS
PfaPF14_0415
GO:0031965 nuclear membrane C
ISS
SpoSPCC14G10.01
GO:0003674 molecular_function F
ND
MmuMGI:1915337
GO:0004140 dephospho-CoA kinase activity F
IDA
AthATCOAE
ISS
AthATCOAE
PfaPF14_0415
SceS000002604
SpoSPCC14G10.01
GO:0005524 ATP binding F
ISS
AthATCOAE
SpoSPCC14G10.01
GO:0008150 biological_process P
ND
MmuMGI:1915337
GO:0015937 coenzyme A biosynthetic process P
IDA
AthATCOAE
IGI
SceS000002604
ISS
AthATCOAE
PfaPF14_0415
SceS000002604
SpoSPCC14G10.01

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_221

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga871 ENSANGP00000014315
Anopheles gambiae (Aga) aga6967 ENSANGP00000017632
Ashbya gossypii (Ago) ago4202 AGL110C
Ashbya gossypii (Ago) ago3956 AGL356C
Arabidopsis thaliana (Ath) ath8681 At2g18250.1
Arabidopsis thaliana (Ath) ath9702 At2g27490.1
Arabidopsis thaliana (Ath) ath9703 At2g27490.2
Caenorhabditis elegans (Cel) cel14683 T05G5.5
(CE23950;
WBGene00011500)
Caenorhabditis elegans (Cel) cel20280 Y65B4A.8
(CE31383;
WBGene00022031)
Candida glabrata (Cgl) cgl1470 CAGL0F05555g
Candida glabrata (Cgl) cgl1641 CAGL0G00352g
Cryptococcus neoformans (Cne) cne5498 179.m00351
Cryptococcus neoformans (Cne) cne5100 186.m04040
Dictyostelium discoideum (Ddi) ddi13115 DDB0231517
Dictyostelium discoideum (Ddi) ddi12857 DDB0231518
Debaryomyces hansenii (Dha) dha2042 DEHA0C13871g
Debaryomyces hansenii (Dha) dha6331 DEHA0G14179g
Drosophila melanogaster (Dme) dme8123 CG10575-PA
(FBgn0035632)
Drosophila melanogaster (Dme) dme11314 CG1939-PA
(FBgn0037469)
Danio rerio (Dre) dre27024 ENSDARP00000016437
Danio rerio (Dre) dre27023 ENSDARP00000021532
Escherichia coli (Eco) eco104 16128096
Encephalitozoon cuniculi (Ecu) ecu918 19074830
Takifugu rubripes (Fru) fru7170 SINFRUP00000164207
Takifugu rubripes (Fru) fru7178 SINFRUP00000164236
Takifugu rubripes (Fru) fru7177 SINFRUP00000164239
Gallus gallus (Gga) gga13756 ENSGALP00000001280
Gallus gallus (Gga) gga13755 ENSGALP00000001281
(DCAKD)
Gallus gallus (Gga) gga25709 ENSGALP00000028060
Homo sapiens (Hsa) hsa13715 ENSP00000163059
Homo sapiens (Hsa) hsa13836 ENSP00000341504
(DCAKD)		 Q8WVC6-1
Kluyveromyces lactis (Kla) kla1825 KLLA0C14003g
Kluyveromyces lactis (Kla) kla2889 KLLA0D18711g
Mus musculus (Mmu) mmu4840 ENSMUSP00000001806
(MGI:1918993)		 Q9DBL7
Mus musculus (Mmu) mmu4934 ENSMUSP00000021313
(MGI:1915337)		 Q8BHC4
Neurospora crassa (Ncr) ncr355 NCU00369.2
Neurospora crassa (Ncr) ncr5859 NCU06029.2
Oryza sativa (Osa) osa11817 2805.m00155
Oryza sativa (Osa) osa78078 7482.m00167
Plasmodium falciparum (Pfa) pfa1866 PF14_0415
Rattus norvegicus (Rno) rno6151 ENSRNOP00000027061
(RGD:1549767)		 Q5XIA5
Rattus norvegicus (Rno) rno6238 ENSRNOP00000037891
(RGD:1359211)		 Q6AY55
Saccharomyces cerevisiae (Sce) sce1240 YDR196C
(S000002604)
Saccharomyces cerevisiae (Sce) sce2661 YGR277C
(S000003509)
Schizosaccharomyces pombe (Spo) spo554 SPAC1F12.08 Q10350
Schizosaccharomyces pombe (Spo) spo10 SPCC14G10.01 O74414
Yarrowia lipolytica (Yli) yli3519 YALI0D19426g
Yarrowia lipolytica (Yli) yli5752 YALI0F09625g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1918993
GO:0005634 nucleus C
IDA
SceS000003509
SpoSPAC1F12.08
GO:0005635 nuclear envelope C
IDA
SceS000002604
GO:0005737 cytoplasm C
IDA
SceS000003509
SpoSPCC14G10.01
GO:0005739 mitochondrion C
IDA
MmuMGI:1915337
SceS000002604
GO:0005773 vacuole C
IDA
AthAt2g27490
GO:0005777 peroxisome C
IDA
AthAt2g27490
GO:0005783 endoplasmic reticulum C
IDA
SceS000002604
ISS
SpoSPCC14G10.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPCC14G10.01
GO:0005829 cytosol C
IDA
SpoSPAC1F12.08
GO:0009507 chloroplast C
IDA
AthAt2g27490
GO:0020011 apicoplast C
ISS
PfaPF14_0415
GO:0031965 nuclear membrane C
ISS
SpoSPCC14G10.01
GO:0003674 molecular_function F
ND
MmuMGI:1915337
GO:0004140 dephospho-CoA kinase activity F
IDA
AthAt2g27490
MmuMGI:1918993
ISA
DmeFBgn0035632
MmuMGI:1918993
ISS
AthAt2g27490
PfaPF14_0415
SceS000002604
SpoSPCC14G10.01
GO:0004595 pantetheine-phosphate adenylyltransferase
activity		 F
IDA
AthAt2g18250
MmuMGI:1918993
IMP
MmuMGI:1918993
ISA
DmeFBgn0035632
MmuMGI:1918993
ISS
SceS000003509
SpoSPAC1F12.08
GO:0005524 ATP binding F
ISS
AthAt2g27490
SpoSPCC14G10.01
GO:0016779 nucleotidyltransferase activity F
ISS
AthAt2g18250
GO:0006629 lipid metabolic process P
IMP
AthAt2g18250
GO:0006970 response to osmotic stress P
IMP
AthAt2g18250
GO:0007297 ovarian follicle cell migration P
IMP
DmeFBgn0035632
GO:0007303 cytoplasmic transport, nurse cell to
oocyte		 P
IMP
DmeFBgn0035632
GO:0007476 imaginal disc-derived wing morphogenesis P
IMP
DmeFBgn0035632
GO:0008150 biological_process P
ND
MmuMGI:1915337
GO:0008152 metabolic process P
IMP
MmuMGI:1918993
GO:0009058 biosynthetic process P
ISS
AthAt2g18250
GO:0009651 response to salt stress P
IMP
AthAt2g18250
GO:0015937 coenzyme A biosynthetic process P
IDA
AthAt2g27490
At2g18250
MmuMGI:1918993
IGI
SceS000002604
S000003509
ISA
DmeFBgn0035632
MmuMGI:1918993
ISS
AthAt2g27490
PfaPF14_0415
SceS000002604
S000003509
SpoSPCC14G10.01
SPAC1F12.08
GO:0016310 phosphorylation P
IDA
MmuMGI:1918993
ISA
MmuMGI:1918993
GO:0019915 lipid storage P
IMP
AthAt2g18250
GO:0040007 growth P
IMP
AthAt2g18250
GO:0070328 triglyceride homeostasis P
IMP
DmeFBgn0035632
GO:0080020 regulation of coenzyme A biosynthetic
process		 P
IMP
AthAt2g18250

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC14G10.01
(O74414)		 YDR196C
(S000002604)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005635 nuclear envelope C
IDA
SceS000002604
GO:0005737 cytoplasm C
IDA
SpoSPCC14G10.01
GO:0005739 mitochondrion C
IDA
SceS000002604
GO:0005783 endoplasmic reticulum C
IDA
SceS000002604
ISS
SpoSPCC14G10.01
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPCC14G10.01
GO:0031965 nuclear membrane C
ISS
SpoSPCC14G10.01
GO:0004140 dephospho-CoA kinase activity F
ISS
SceS000002604
SpoSPCC14G10.01
GO:0005524 ATP binding F
ISS
SpoSPCC14G10.01
GO:0015937 coenzyme A biosynthetic process P
IGI
SceS000002604
ISS
SceS000002604
SpoSPCC14G10.01

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