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Search term: YDR205W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSC2
SGD link S000002613
Alternative ID YDR205W
Description Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids
Synonyms YDR205W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1484 ACDHYP-

KOGs classification KOGs description
METABOLISM Putative Zn2+ transporter MSC2 (cation diffusion facilitator superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g04620 GI:15224038
Arabidopsis thaliana (Ath) At3g12100 GI:15229954
Caenorhabditis elegans (Cel) CE15207
(WBGene00006590)		 GI:17555372
Caenorhabditis elegans (Cel) CE26955_2 GI:17510749
Drosophila melanogaster (Dme) 7299414 GI:7299414
Homo sapiens (Hsa) Hs19424134 GI:19424134
Homo sapiens (Hsa) Hs20070323_2
(SLC30A5)		 GI:20070323 Q9H9X0
Homo sapiens (Hsa) Hs21687224 GI:18552230
Homo sapiens (Hsa) Hs22041687 GI:22041687
Homo sapiens (Hsa) HsM8923691_1 GI:8923691
Saccharomyces cerevisiae (Sce) YDR205w
(S000002613)		 GI:6320411
Schizosaccharomyces pombe (Spo) SPAC17D4.03c GI:19115606 Q9HGQ3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SpoSPAC17D4.03c
GO:0005624 membrane fraction C
IDA
HsaSLC30A5
NAS
HsaSLC30A5
GO:0005783 endoplasmic reticulum C
IDA
SceS000002613
SpoSPAC17D4.03c
GO:0005794 Golgi apparatus C
IDA
HsaSLC30A5
GO:0005887 integral to plasma membrane C
TAS
HsaSLC30A5
GO:0016020 membrane C
ISS
AthAt3g12100
At2g04620
GO:0016021 integral to membrane C
ISS
SceS000002613
GO:0016324 apical plasma membrane C
IDA
HsaSLC30A5
GO:0030141 stored secretory granule C
IDA
HsaSLC30A5
GO:0030667 secretory granule membrane C
EXP
HsaSLC30A5
GO:0005385 zinc ion transmembrane transporter
activity		 F
EXP
HsaSLC30A5
IDA
HsaSLC30A5
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0005515 protein binding F
IPI
SpoSPAC17D4.03c
GO:0008270 zinc ion binding F
NAS
HsaSLC30A5
GO:0008324 cation transmembrane transporter
activity		 F
ISS
AthAt3g12100
At2g04620
GO:0015562 efflux transmembrane transporter
activity		 F
ISS
AthAt3g12100
At2g04620
GO:0046873 metal ion transmembrane transporter
activity		 F
ISS
SceS000002613
GO:0006812 cation transport P
ISS
AthAt3g12100
At2g04620
GO:0006824 cobalt ion transport P
IDA
HsaSLC30A5
GO:0006829 zinc ion transport P
IDA
HsaSLC30A5
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0006882 cellular zinc ion homeostasis P
IDA
HsaSLC30A5
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0009624 response to nematode P
IEP
AthAt3g12100
GO:0010043 response to zinc ion P
IDA
HsaSLC30A5
GO:0010155 regulation of proton transport P
NAS
HsaSLC30A5
GO:0015674 di-, tri-valent inorganic cation
transport		 P
IMP
SpoSPAC17D4.03c
GO:0016192 vesicle-mediated transport P
IMP
SpoSPAC17D4.03c
GO:0018991 oviposition P
IMP
CelWBGene00006590
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006590
GO:0055085 transmembrane transport P
IMP
SceS000002613
GO:0071577 zinc ion transmembrane transport P
IMP
SpoSPAC17D4.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38724

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MSC2
(S000002613)		 GI:37362632
Kluyveromyces lactis (Kla) KLLA0F20746g GI:50311959
Eremothecium gossypii (Ego) AGOS_AGL102W GI:45200995


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000002613
GO:0016021 integral to membrane C
ISS
SceS000002613
GO:0005385 zinc ion transmembrane transporter
activity		 F
IMP
SceS000002613
GO:0046873 metal ion transmembrane transporter
activity		 F
ISS
SceS000002613
GO:0006829 zinc ion transport P
IMP
SceS000002613
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000002613
GO:0055085 transmembrane transport P
IMP
SceS000002613

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1426

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7011 ENSANGP00000017072
Anopheles gambiae (Aga) aga7012 ENSANGP00000022612
Ashbya gossypii (Ago) ago4210 AGL102W
Arabidopsis thaliana (Ath) ath7869 At2g04620.1
Caenorhabditis elegans (Cel) cel17512 Y105E8A.3
(CE32233;
WBGene00013668)
Candida glabrata (Cgl) cgl1463 CAGL0F05401g
Dictyostelium discoideum (Ddi) ddi10197 DDB0189258
Debaryomyces hansenii (Dha) dha6328 DEHA0G14113g
Drosophila melanogaster (Dme) dme11998 CG6672-PA
(FBgn0037875)
Danio rerio (Dre) dre14304 ENSDARP00000005251 Q1LVV4
Danio rerio (Dre) dre1227 ENSDARP00000014137
Danio rerio (Dre) dre1226 ENSDARP00000015706
Danio rerio (Dre) dre14305 ENSDARP00000023202
Danio rerio (Dre) dre14306 ENSDARP00000040320
Takifugu rubripes (Fru) fru7070 SINFRUP00000145481
Takifugu rubripes (Fru) fru7071 SINFRUP00000172276
Gallus gallus (Gga) gga3932 ENSGALP00000009135
Gallus gallus (Gga) gga27595 ENSGALP00000023825
(SLC30A5)		 Q5ZLF4
Gallus gallus (Gga) gga27596 ENSGALP00000023826
Gallus gallus (Gga) gga27597 ENSGALP00000023827
Homo sapiens (Hsa) hsa1572 ENSP00000294731
Homo sapiens (Hsa) hsa25319 ENSP00000296670
(SLC30A5)		 Q8TAD4-2
Homo sapiens (Hsa) hsa1573 ENSP00000350278
(SLC30A7)		 Q8NEW0
Homo sapiens (Hsa) hsa25318 ENSP00000352868
Kluyveromyces lactis (Kla) kla5011 KLLA0F20746g
Mus musculus (Mmu) mmu7477 ENSMUSP00000022129
(MGI:1916298)		 Q8C2T4
Mus musculus (Mmu) mmu17447 ENSMUSP00000065254
(MGI:1913750)		 Q9JKN1
Mus musculus (Mmu) mmu7478 ENSMUSP00000065764
(MGI:1916298)		 Q8R4H9
Neurospora crassa (Ncr) ncr7068 NCU07262.2
Oryza sativa (Osa) osa66773 6936.m00136
Rattus norvegicus (Rno) rno16907 ENSRNOP00000019172
(RGD:1307873)		 Q5BJM8
Rattus norvegicus (Rno) rno15446 ENSRNOP00000025445
(RGD:1306931)
Rattus norvegicus (Rno) rno15445 ENSRNOP00000025506
(RGD:1306931)
Saccharomyces cerevisiae (Sce) sce1249 YDR205W
(S000002613)
Schizosaccharomyces pombe (Spo) spo2044 SPAC17D4.03c Q9HGQ3
Yarrowia lipolytica (Yli) yli2453 YALI0C18359g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
EXP
MmuMGI:1913750
IDA
SpoSPAC17D4.03c
GO:0005624 membrane fraction C
ISA
MmuMGI:1916298
GO:0005737 cytoplasm C
IDA
MmuMGI:1913750
GO:0005783 endoplasmic reticulum C
IDA
SceS000002613
SpoSPAC17D4.03c
GO:0005794 Golgi apparatus C
IDA
MmuMGI:1913750
ISA
MmuMGI:1916298
GO:0016020 membrane C
ISS
AthAt2g04620
GO:0016021 integral to membrane C
ISS
SceS000002613
GO:0016023 cytoplasmic membrane-bounded vesicle C
IDA
MmuMGI:1913750
GO:0016324 apical plasma membrane C
ISA
MmuMGI:1916298
GO:0030141 stored secretory granule C
ISA
MmuMGI:1916298
GO:0048471 perinuclear region of cytoplasm C
IDA
MmuMGI:1913750
GO:0005385 zinc ion transmembrane transporter
activity		 F
EXP
MmuMGI:1913750
IMP
SceS000002613
SpoSPAC17D4.03c
ISA
MmuMGI:1916298
ISS
DmeFBgn0037875
GO:0005515 protein binding F
IPI
SpoSPAC17D4.03c
GO:0008270 zinc ion binding F
IC
MmuMGI:1913750
GO:0008324 cation transmembrane transporter
activity		 F
ISS
AthAt2g04620
GO:0015562 efflux transmembrane transporter
activity		 F
ISS
AthAt2g04620
GO:0046873 metal ion transmembrane transporter
activity		 F
ISS
SceS000002613
GO:0000003 reproduction P
IMP
CelWBGene00013668
GO:0006812 cation transport P
ISS
AthAt2g04620
GO:0006824 cobalt ion transport P
ISA
MmuMGI:1916298
GO:0006829 zinc ion transport P
IDA
MmuMGI:1913750
IMP
SceS000002613
SpoSPAC17D4.03c
ISA
MmuMGI:1916298
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0015674 di-, tri-valent inorganic cation
transport		 P
EXP
MmuMGI:1913750
IMP
SpoSPAC17D4.03c
GO:0016192 vesicle-mediated transport P
IMP
SpoSPAC17D4.03c
GO:0032119 sequestering of zinc ion P
IEP
MmuMGI:1913750
GO:0055085 transmembrane transport P
IMP
SceS000002613
GO:0071577 zinc ion transmembrane transport P
EXP
MmuMGI:1913750
IMP
SpoSPAC17D4.03c
ISA
MmuMGI:1916298

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC17D4.03c
(Q9HGQ3)		 YDR205W
(S000002613)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SpoSPAC17D4.03c
GO:0005783 endoplasmic reticulum C
IDA
SceS000002613
SpoSPAC17D4.03c
GO:0016021 integral to membrane C
ISS
SceS000002613
GO:0005385 zinc ion transmembrane transporter
activity		 F
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0005515 protein binding F
IPI
SpoSPAC17D4.03c
GO:0046873 metal ion transmembrane transporter
activity		 F
ISS
SceS000002613
GO:0006829 zinc ion transport P
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000002613
SpoSPAC17D4.03c
GO:0015674 di-, tri-valent inorganic cation
transport		 P
IMP
SpoSPAC17D4.03c
GO:0016192 vesicle-mediated transport P
IMP
SpoSPAC17D4.03c
GO:0055085 transmembrane transport P
IMP
SceS000002613
GO:0071577 zinc ion transmembrane transport P
IMP
SpoSPAC17D4.03c

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GO info in one table:

s.khadayate@ucl.ac.uk