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Search term: YDR212W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TCP1
SGD link S000002620
Alternative ID YDR212W
Description Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein
Synonyms YDR212W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0360 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Chaperonin complex component, TCP-1 alpha subunit (CCT1)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g20050 GI:15231024
Caenorhabditis elegans (Cel) CE02319
(WBGene00000377)		 GI:17532601 P41988
Drosophila melanogaster (Dme) 7300868 GI:13959710
Homo sapiens (Hsa) Hs13375956 GI:13375956
Homo sapiens (Hsa) Hs13540473 GI:13540473
Homo sapiens (Hsa) Hs20475511 GI:20475511
Homo sapiens (Hsa) Hs20541740 GI:20541740
Homo sapiens (Hsa) Hs20549894 GI:20549894
Homo sapiens (Hsa) Hs22062802 GI:22062802
Homo sapiens (Hsa) Hs9055272
(MKKS)		 GI:9055272 Q9H6M6
Saccharomyces cerevisiae (Sce) YDR212w
(S000002620)		 GI:6320418 P12612
Schizosaccharomyces pombe (Spo) SPBC12D12.03 GI:19112741 O94501
Encephalitozoon cuniculi (Ecu) ECU03g0220 GI:19172982 Q8SSC9
Arabidopsis thaliana (Ath) At3g20050 GI:15231024
Caenorhabditis elegans (Cel) CE02319
(WBGene00000377)		 GI:17532601 P41988
Drosophila melanogaster (Dme) 7300868 GI:13959710
Homo sapiens (Hsa) Hs13375956 GI:13375956
Homo sapiens (Hsa) Hs13540473 GI:13540473
Homo sapiens (Hsa) Hs20475511 GI:20475511
Homo sapiens (Hsa) Hs20541740 GI:20541740
Homo sapiens (Hsa) Hs20549894 GI:20549894
Homo sapiens (Hsa) Hs22062802 GI:22062802
Homo sapiens (Hsa) Hs9055272
(MKKS)		 GI:9055272 Q9H6M6
Saccharomyces cerevisiae (Sce) YDR212w
(S000002620)		 GI:6320418 P12612
Schizosaccharomyces pombe (Spo) SPBC12D12.03 GI:19112741 O94501
Encephalitozoon cuniculi (Ecu) ECU03g0220 GI:19172982 Q8SSC9
Arabidopsis thaliana (Ath) At3g20050 GI:15231024
Caenorhabditis elegans (Cel) CE02319
(WBGene00000377)		 GI:17532601 P41988
Drosophila melanogaster (Dme) 7300868 GI:13959710
Homo sapiens (Hsa) Hs13375956 GI:13375956
Homo sapiens (Hsa) Hs13540473 GI:13540473
Homo sapiens (Hsa) Hs20475511 GI:20475511
Homo sapiens (Hsa) Hs20541740 GI:20541740
Homo sapiens (Hsa) Hs20549894 GI:20549894
Homo sapiens (Hsa) Hs22062802 GI:22062802
Homo sapiens (Hsa) Hs9055272
(MKKS)		 GI:9055272 Q9H6M6
Saccharomyces cerevisiae (Sce) YDR212w
(S000002620)		 GI:6320418 P12612
Schizosaccharomyces pombe (Spo) SPBC12D12.03 GI:19112741 O94501
Encephalitozoon cuniculi (Ecu) ECU03g0220 GI:19172982 Q8SSC9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002620
GO:0005575 cellular_component C
ND
AthAt3g20050
GO:0005622 intracellular C
IDA
HsaMKKS
GO:0005634 nucleus C
IDA
SpoSPBC12D12.03
GO:0005737 cytoplasm C
ISS
SpoSPBC12D12.03
GO:0005829 cytosol C
IDA
SpoSPBC12D12.03
GO:0005832 chaperonin-containing T-complex C
IDA
SceS000002620
SpoSPBC12D12.03
IPI
SceS000002620
GO:0005856 cytoskeleton C
ISS
SpoSPBC12D12.03
GO:0031514 motile secondary cilium C
ISS
HsaMKKS
GO:0005524 ATP binding F
ISS
SpoSPBC12D12.03
GO:0051082 unfolded protein binding F
IDA
SceS000002620
ISS
SpoSPBC12D12.03
TAS
HsaMKKS
GO:0000003 reproduction P
IMP
CelWBGene00000377
GO:0001947 heart looping P
ISS
HsaMKKS
GO:0002119 nematode larval development P
IMP
CelWBGene00000377
GO:0006457 protein folding P
IDA
SceS000002620
ISS
SpoSPBC12D12.03
TAS
HsaMKKS
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000377
GO:0007010 cytoskeleton organization P
ISS
SpoSPBC12D12.03
GO:0007021 tubulin complex assembly P
IC
SpoSPBC12D12.03
GO:0007286 spermatid development P
ISS
HsaMKKS
GO:0007368 determination of left/right symmetry P
ISS
HsaMKKS
GO:0007507 heart development P
TAS
HsaMKKS
GO:0007608 sensory perception of smell P
ISS
HsaMKKS
GO:0008406 gonad development P
TAS
HsaMKKS
GO:0009296 flagellum assembly P
ISS
HsaMKKS
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000377
GO:0021756 striatum development P
ISS
HsaMKKS
GO:0021766 hippocampus development P
ISS
HsaMKKS
GO:0021987 cerebral cortex development P
ISS
HsaMKKS
GO:0032402 melanosome transport P
ISS
HsaMKKS
GO:0035176 social behavior P
ISS
HsaMKKS
GO:0040007 growth P
IMP
CelWBGene00000377
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000377
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000377
GO:0040039 inductive cell migration P
IMP
CelWBGene00000377
GO:0042384 cilium assembly P
ISS
HsaMKKS
GO:0045444 fat cell differentiation P
ISS
HsaMKKS
GO:0045494 photoreceptor cell maintenance P
ISS
HsaMKKS
GO:0046907 intracellular transport P
ISS
HsaMKKS
GO:0048854 brain morphogenesis P
ISS
HsaMKKS
GO:0050910 detection of mechanical stimulus involved in
sensory perception of sound		 P
ISS
HsaMKKS
GO:0051877 pigment granule aggregation in cell
center		 P
ISS
HsaMKKS
GO:0060027 convergent extension involved in
gastrulation		 P
ISS
HsaMKKS
GO:0060271 cilium morphogenesis P
ISS
HsaMKKS
GO:0060296 regulation of cilium beat frequency involved in
ciliary motility		 P
ISS
HsaMKKS

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5656

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TCP1 GI:57863257
Pan troglodytes (Ptr) TCP1 GI:114610017
Canis familiaris (Cfa) TCP1 GI:57032236
Mus musculus (Mmu) Tcp1
(MGI:98535)		 GI:110625624 P11983
Rattus norvegicus (Rno) Tcp1
(RGD:3832)		 GI:6981642 34475
Gallus gallus (Gga) TCP1 GI:57530301
Drosophila melanogaster (Dme) T-cp1
(FBgn0003676)		 GI:24649029
Anopheles gambiae (Aga) AgaP_AGAP004238 GI:158291637
Caenorhabditis elegans (Cel) cct-1
(CE02319;
WBGene00000377)		 GI:17532601 P41988
Schizosaccharomyces pombe (Spo) cct1
(SPBC12D12.03)		 GI:19112741 O94501
Saccharomyces cerevisiae (Sce) TCP1
(S000002620)		 GI:6320418 P12612
Kluyveromyces lactis (Kla) KLLA0A04191g GI:50302501
Eremothecium gossypii (Ego) AGOS_AGL092W GI:45201004
Magnaporthe grisea (Mgr) MGG_10358 GI:39969495
Neurospora crassa (Ncr) NCU04448.1 GI:32406376
Arabidopsis thaliana (Ath) ATTCP-1 GI:15231024
Oryza sativa (Osa) Os04g0551800 GI:115459800
Plasmodium falciparum (Pfa) PF11_0331 GI:124804435


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000242 pericentriolar material C
IDA
MmuMGI:98535
GO:0000792 heterochromatin C
ISO
MmuMGI:98535
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002620
GO:0005575 cellular_component C
ND
AthATTCP-1
GO:0005634 nucleus C
IDA
SpoSPBC12D12.03
GO:0005720 nuclear heterochromatin C
IDA
MmuMGI:98535
GO:0005737 cytoplasm C
ISS
SpoSPBC12D12.03
GO:0005753 mitochondrial proton-transporting ATP synthase
complex		 C
NAS
DmeFBgn0003676
GO:0005815 microtubule organizing center C
IDA
MmuMGI:98535
GO:0005829 cytosol C
EXP
HsaTCP1
IDA
SpoSPBC12D12.03
GO:0005832 chaperonin-containing T-complex C
IDA
MmuMGI:98535
SceS000002620
SpoSPBC12D12.03
IPI
SceS000002620
ISS
DmeFBgn0003676
PfaPF11_0331
GO:0005856 cytoskeleton C
ISS
SpoSPBC12D12.03
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0003676
GO:0005515 protein binding F
IPI
MmuMGI:98535
GO:0005524 ATP binding F
ISS
SpoSPBC12D12.03
NAS
DmeFBgn0003676
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
NAS
DmeFBgn0003676
GO:0051082 unfolded protein binding F
IDA
SceS000002620
ISS
DmeFBgn0003676
SpoSPBC12D12.03
GO:0000003 reproduction P
IMP
CelWBGene00000377
GO:0002119 nematode larval development P
IMP
CelWBGene00000377
GO:0006457 protein folding P
IDA
SceS000002620
ISS
DmeFBgn0003676
SpoSPBC12D12.03
NAS
DmeFBgn0003676
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000377
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0003676
GO:0007010 cytoskeleton organization P
ISS
PfaPF11_0331
SpoSPBC12D12.03
GO:0007021 tubulin complex assembly P
IC
SpoSPBC12D12.03
NAS
HsaTCP1
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0003676
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000377
GO:0040007 growth P
IMP
CelWBGene00000377
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000377
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000377
GO:0040039 inductive cell migration P
IMP
CelWBGene00000377

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1809

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6760 ENSANGP00000013382
Ashbya gossypii (Ago) ago4219 AGL092W
Arabidopsis thaliana (Ath) ath14292 At3g20050.1
Caenorhabditis elegans (Cel) cel14620 T05C12.7
(CE02319;
WBGene00000377)
Candida glabrata (Cgl) cgl1569 CAGL0F07887g
Cryptococcus neoformans (Cne) cne5232 179.m00079
Dictyostelium discoideum (Ddi) ddi11453 DDB0191128
Debaryomyces hansenii (Dha) dha6373 DEHA0G15081g
Drosophila melanogaster (Dme) dme13861 CG5374-PA
(FBgn0003676)
Drosophila melanogaster (Dme) dme13862 CG5374-PB
(FBgn0003676)
Danio rerio (Dre) dre27244 ENSDARP00000015050
(tcp1)		 Q803P2
Encephalitozoon cuniculi (Ecu) ecu389 19172982
Takifugu rubripes (Fru) fru22550 SINFRUP00000152838
Gallus gallus (Gga) gga15152 ENSGALP00000018987
(TCP1)		 Q5ZMG9
Gallus gallus (Gga) gga15154 ENSGALP00000018990
Homo sapiens (Hsa) hsa27995 ENSP00000239585
Kluyveromyces lactis (Kla) kla182 KLLA0A04191g
Mus musculus (Mmu) mmu31397 ENSMUSP00000075341
Mus musculus (Mmu) mmu31416 ENSMUSP00000079276
Neurospora crassa (Ncr) ncr4319 NCU04448.2
Oryza sativa (Osa) osa82784 8281.m00173
Plasmodium falciparum (Pfa) pfa782 PF11_0331
Rattus norvegicus (Rno) rno451 ENSRNOP00000019531
(RGD:3832)		 P28480
Saccharomyces cerevisiae (Sce) sce1260 YDR212W
(S000002620)
Schizosaccharomyces pombe (Spo) spo196 SPBC12D12.03 O94501
Yarrowia lipolytica (Yli) yli1400 YALI0B15774g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002620
GO:0005575 cellular_component C
ND
AthAt3g20050
GO:0005634 nucleus C
IDA
SpoSPBC12D12.03
GO:0005737 cytoplasm C
ISS
SpoSPBC12D12.03
GO:0005753 mitochondrial proton-transporting ATP synthase
complex		 C
NAS
DmeFBgn0003676
GO:0005829 cytosol C
IDA
SpoSPBC12D12.03
GO:0005832 chaperonin-containing T-complex C
IDA
SceS000002620
SpoSPBC12D12.03
IPI
SceS000002620
ISS
DmeFBgn0003676
PfaPF11_0331
GO:0005856 cytoskeleton C
ISS
SpoSPBC12D12.03
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0003676
GO:0005524 ATP binding F
ISS
SpoSPBC12D12.03
NAS
DmeFBgn0003676
GO:0008553 hydrogen-exporting ATPase activity,
phosphorylative mechanism		 F
NAS
DmeFBgn0003676
GO:0051082 unfolded protein binding F
IDA
SceS000002620
ISS
DmeFBgn0003676
SpoSPBC12D12.03
GO:0000003 reproduction P
IMP
CelWBGene00000377
GO:0002119 nematode larval development P
IMP
CelWBGene00000377
GO:0006457 protein folding P
IDA
SceS000002620
ISS
DmeFBgn0003676
SpoSPBC12D12.03
NAS
DmeFBgn0003676
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00000377
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0003676
GO:0007010 cytoskeleton organization P
ISS
PfaPF11_0331
SpoSPBC12D12.03
GO:0007021 tubulin complex assembly P
IC
SpoSPBC12D12.03
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0003676
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000377
GO:0040007 growth P
IMP
CelWBGene00000377
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00000377
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000377
GO:0040039 inductive cell migration P
IMP
CelWBGene00000377

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC12D12.03
(O94501)		 YDR212W
(S000002620)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000002620
GO:0005634 nucleus C
IDA
SpoSPBC12D12.03
GO:0005737 cytoplasm C
ISS
SpoSPBC12D12.03
GO:0005829 cytosol C
IDA
SpoSPBC12D12.03
GO:0005832 chaperonin-containing T-complex C
IDA
SceS000002620
SpoSPBC12D12.03
IPI
SceS000002620
GO:0005856 cytoskeleton C
ISS
SpoSPBC12D12.03
GO:0005524 ATP binding F
ISS
SpoSPBC12D12.03
GO:0051082 unfolded protein binding F
IDA
SceS000002620
ISS
SpoSPBC12D12.03
GO:0006457 protein folding P
IDA
SceS000002620
ISS
SpoSPBC12D12.03
GO:0007010 cytoskeleton organization P
ISS
SpoSPBC12D12.03
GO:0007021 tubulin complex assembly P
IC
SpoSPBC12D12.03

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