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Search term: YDR254W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CHL4
SGD link S000002662
Alternative ID YDR254W
Description Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p
Synonyms YDR254W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38741

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) CHL4
(S000002662)		 GI:6320460
Kluyveromyces lactis (Kla) KLLA0D11770g GI:50307215
Eremothecium gossypii (Ego) AGOS_AGL251C GI:45200846


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000942 outer kinetochore of condensed nuclear
chromosome		 C
IDA
SceS000002662
GO:0005819 spindle C
RCA
SceS000002662
GO:0005856 cytoskeleton C
RCA
SceS000002662
GO:0015630 microtubule cytoskeleton C
RCA
SceS000002662
GO:0044430 cytoskeletal part C
RCA
SceS000002662
GO:0005198 structural molecule activity F
IMP
SceS000002662
GO:0000226 microtubule cytoskeleton organization P
RCA
SceS000002662
GO:0000278 mitotic cell cycle P
RCA
SceS000002662
GO:0000279 M phase P
RCA
SceS000002662
GO:0007059 chromosome segregation P
IMP
SceS000002662
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034089 establishment of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034090 maintenance of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000002662
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000002662
GO:0051382 kinetochore assembly P
IMP
SceS000002662
GO:0071459 protein localization to chromosome, centromeric
region		 P
IMP
SceS000002662

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15165

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4061 AGL251C
Candida glabrata (Cgl) cgl321 CAGL0B02673g
Debaryomyces hansenii (Dha) dha2940 DEHA0D14366g
Kluyveromyces lactis (Kla) kla2585 KLLA0D11770g
Neurospora crassa (Ncr) ncr3428 NCU03537.2
Saccharomyces cerevisiae (Sce) sce1303 YDR254W
(S000002662)
Schizosaccharomyces pombe (Spo) spo4144 SPBP22H7.09c Q9C0W0
Yarrowia lipolytica (Yli) yli128 YALI0A03531g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000779 condensed chromosome, centromeric
region		 C
IDA
SpoSPBP22H7.09c
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP22H7.09c
GO:0000942 outer kinetochore of condensed nuclear
chromosome		 C
IDA
SceS000002662
GO:0005634 nucleus C
IDA
SpoSPBP22H7.09c
NAS
SpoSPBP22H7.09c
GO:0005816 spindle pole body C
IDA
SpoSPBP22H7.09c
GO:0005819 spindle C
RCA
SceS000002662
GO:0005856 cytoskeleton C
RCA
SceS000002662
GO:0015630 microtubule cytoskeleton C
RCA
SceS000002662
GO:0031511 Mis6-Sim4 complex C
TAS
SpoSPBP22H7.09c
GO:0044430 cytoskeletal part C
RCA
SceS000002662
GO:0005198 structural molecule activity F
IMP
SceS000002662
GO:0005515 protein binding F
IPI
SpoSPBP22H7.09c
GO:0000226 microtubule cytoskeleton organization P
RCA
SceS000002662
GO:0000278 mitotic cell cycle P
RCA
SceS000002662
GO:0000279 M phase P
RCA
SceS000002662
GO:0007049 cell cycle P
NAS
SpoSPBP22H7.09c
GO:0007059 chromosome segregation P
IMP
SceS000002662
SpoSPBP22H7.09c
GO:0031055 chromatin remodeling at centromere P
IMP
SpoSPBP22H7.09c
GO:0034080 CenH3-containing nucleosome assembly at
centromere		 P
TAS
SpoSPBP22H7.09c
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034089 establishment of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034090 maintenance of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034613 cellular protein localization P
IGI
SpoSPBP22H7.09c
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000002662
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000002662
GO:0051382 kinetochore assembly P
IMP
SceS000002662
TAS
SpoSPBP22H7.09c
GO:0071459 protein localization to chromosome, centromeric
region		 P
IMP
SceS000002662

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP22H7.09c
(Q9C0W0)		 YDR254W
(S000002662)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000779 condensed chromosome, centromeric
region		 C
IDA
SpoSPBP22H7.09c
GO:0000939 inner kinetochore of condensed
chromosome		 C
IDA
SpoSPBP22H7.09c
GO:0000942 outer kinetochore of condensed nuclear
chromosome		 C
IDA
SceS000002662
GO:0005634 nucleus C
IDA
SpoSPBP22H7.09c
NAS
SpoSPBP22H7.09c
GO:0005816 spindle pole body C
IDA
SpoSPBP22H7.09c
GO:0005819 spindle C
RCA
SceS000002662
GO:0005856 cytoskeleton C
RCA
SceS000002662
GO:0015630 microtubule cytoskeleton C
RCA
SceS000002662
GO:0031511 Mis6-Sim4 complex C
TAS
SpoSPBP22H7.09c
GO:0044430 cytoskeletal part C
RCA
SceS000002662
GO:0005198 structural molecule activity F
IMP
SceS000002662
GO:0005515 protein binding F
IPI
SpoSPBP22H7.09c
GO:0000226 microtubule cytoskeleton organization P
RCA
SceS000002662
GO:0000278 mitotic cell cycle P
RCA
SceS000002662
GO:0000279 M phase P
RCA
SceS000002662
GO:0007049 cell cycle P
NAS
SpoSPBP22H7.09c
GO:0007059 chromosome segregation P
IMP
SceS000002662
SpoSPBP22H7.09c
GO:0031055 chromatin remodeling at centromere P
IMP
SpoSPBP22H7.09c
GO:0034080 CenH3-containing nucleosome assembly at
centromere		 P
TAS
SpoSPBP22H7.09c
GO:0034087 establishment of mitotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034089 establishment of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034090 maintenance of meiotic sister chromatid
cohesion		 P
IMP
SceS000002662
GO:0034613 cellular protein localization P
IGI
SpoSPBP22H7.09c
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000002662
GO:0051248 negative regulation of protein metabolic
process		 P
RCA
SceS000002662
GO:0051382 kinetochore assembly P
IMP
SceS000002662
TAS
SpoSPBP22H7.09c
GO:0071459 protein localization to chromosome, centromeric
region		 P
IMP
SceS000002662

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

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