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Search term: YDR255C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RMD5
SGD link S000002663
Alternative ID YDR255C
Description Conserved protein that has an E3-like ubiquitin ligase activity necessary for polyubiquitination and degradation of the gluconeogenic enzyme fructose-1,6-bisphosphatase; also required for sporulation; has a degenerate RING finger domain
Synonyms YDR255C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2817 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted E3 ubiquitin ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g22690 GI:18400050
Arabidopsis thaliana (Ath) At4g37880 GI:15235735
Arabidopsis thaliana (Ath) At5g09630 GI:15242463
Caenorhabditis elegans (Cel) CE29467
(WBGene00020301)		 GI:17569657 Q22302
Drosophila melanogaster (Dme) 7291223
(FBgn0034573)		 GI:20130193
Homo sapiens (Hsa) Hs12232469
(RMND5A)		 GI:12232469 Q9H871
Homo sapiens (Hsa) Hs21362098 GI:14602811 Q96G75
Homo sapiens (Hsa) HsM12232433 GI:12232433
Saccharomyces cerevisiae (Sce) YDR255c
(S000002663)		 GI:6320461 Q12508
Schizosaccharomyces pombe (Spo) SPBC29A3.03c GI:19112623 O59668
Encephalitozoon cuniculi (Ecu) ECU04g1430 GI:19074222 Q8SVR1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g37880
At5g09630
GO:0005634 nucleus C
IDA
SpoSPBC29A3.03c
GO:0005829 cytosol C
IDA
SceS000002663
SpoSPBC29A3.03c
ISS
SpoSPBC29A3.03c
GO:0034657 GID complex C
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0008270 zinc ion binding F
ISS
SpoSPBC29A3.03c
GO:0006914 autophagy P
RCA
SceS000002663
GO:0008150 biological_process P
ND
AthAt4g37880
At5g09630
GO:0016567 protein ubiquitination P
ISS
SpoSPBC29A3.03c
GO:0033554 cellular response to stress P
IEP
SpoSPBC29A3.03c
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002663
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IC
SpoSPBC29A3.03c
IMP
SceS000002663
GO:0045721 negative regulation of gluconeogenesis P
IMP
SceS000002663
ISS
SpoSPBC29A3.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68645

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RMD5
(S000002663)		 GI:6320461 Q12508
Kluyveromyces lactis (Kla) KLLA0D11704g GI:50307209
Eremothecium gossypii (Ego) AGOS_AGL254W GI:45200843


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SceS000002663
GO:0034657 GID complex C
IDA
SceS000002663
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002663
GO:0006914 autophagy P
RCA
SceS000002663
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002663
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002663
GO:0045721 negative regulation of gluconeogenesis P
IMP
SceS000002663

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2229

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9036 ENSANGP00000021271
Ashbya gossypii (Ago) ago4058 AGL254W
Arabidopsis thaliana (Ath) ath9165 At2g22690.1
Arabidopsis thaliana (Ath) ath21972 At4g37880.1
Arabidopsis thaliana (Ath) ath23156 At5g09630.1
Caenorhabditis elegans (Cel) cel14869 T07D1.2
(CE29467;
WBGene00020301)
Candida glabrata (Cgl) cgl322 CAGL0B02695g
Cryptococcus neoformans (Cne) cne1013 163.m06515
Dictyostelium discoideum (Ddi) ddi3129 DDB0217500
Debaryomyces hansenii (Dha) dha2937 DEHA0D14300g
Drosophila melanogaster (Dme) dme6252 CG3295-PA
(FBgn0034573)
Encephalitozoon cuniculi (Ecu) ecu860 19074222
Takifugu rubripes (Fru) fru18473 SINFRUP00000137246
Gallus gallus (Gga) gga18456 ENSGALP00000025450
(RMND5A)		 Q5ZKF8
Gallus gallus (Gga) gga18457 ENSGALP00000025451
Homo sapiens (Hsa) hsa18130 ENSP00000283632
(RMND5A)		 Q9H871-1
Homo sapiens (Hsa) hsa26262 ENSP00000320623
(RMND5B)		 Q96G75-1
Homo sapiens (Hsa) hsa26260 ENSP00000321019
(CDKN1C)		 P49918-2
Homo sapiens (Hsa) hsa18131 ENSP00000338517
Kluyveromyces lactis (Kla) kla2582 KLLA0D11704g
Mus musculus (Mmu) mmu3604 ENSMUSP00000001081
(MGI:1913339)		 Q91YQ7
Mus musculus (Mmu) mmu22094 ENSMUSP00000002292
(MGI:1915727)		 Q80YQ8
Neurospora crassa (Ncr) ncr874 NCU00898.2
Oryza sativa (Osa) osa2540 1947.m00135
Oryza sativa (Osa) osa2694 1950.m00159
Oryza sativa (Osa) osa61429 6592.m00197
Rattus norvegicus (Rno) rno21606 ENSRNOP00000032033
(RGD:1309766)
Rattus norvegicus (Rno) rno4936 ENSRNOP00000036701
(RGD:1559511)		 Q566Q9
Saccharomyces cerevisiae (Sce) sce1304 YDR255C
(S000002663)
Schizosaccharomyces pombe (Spo) spo113 SPBC29A3.03c O59668
Yarrowia lipolytica (Yli) yli629 YALI0A18788g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g37880
At5g09630
MmuMGI:1913339
MGI:1915727
GO:0005634 nucleus C
IDA
SpoSPBC29A3.03c
GO:0005829 cytosol C
IDA
SceS000002663
SpoSPBC29A3.03c
ISS
SpoSPBC29A3.03c
GO:0034657 GID complex C
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0003674 molecular_function F
ND
MmuMGI:1913339
MGI:1915727
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0008270 zinc ion binding F
ISS
SpoSPBC29A3.03c
GO:0006914 autophagy P
RCA
SceS000002663
GO:0008150 biological_process P
ND
AthAt4g37880
At5g09630
MmuMGI:1913339
MGI:1915727
GO:0016567 protein ubiquitination P
ISS
SpoSPBC29A3.03c
GO:0033554 cellular response to stress P
IEP
SpoSPBC29A3.03c
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002663
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IC
SpoSPBC29A3.03c
IMP
SceS000002663
GO:0045721 negative regulation of gluconeogenesis P
IMP
SceS000002663
ISS
SpoSPBC29A3.03c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC29A3.03c
(O59668)		 YDR255C
(S000002663)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC29A3.03c
GO:0005829 cytosol C
IDA
SceS000002663
SpoSPBC29A3.03c
ISS
SpoSPBC29A3.03c
GO:0034657 GID complex C
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000002663
ISS
SpoSPBC29A3.03c
GO:0008270 zinc ion binding F
ISS
SpoSPBC29A3.03c
GO:0006914 autophagy P
RCA
SceS000002663
GO:0016567 protein ubiquitination P
ISS
SpoSPBC29A3.03c
GO:0033554 cellular response to stress P
IEP
SpoSPBC29A3.03c
GO:0042787 protein ubiquitination involved in
ubiquitin-dependent protein catabolic
process		 P
IMP
SceS000002663
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IC
SpoSPBC29A3.03c
IMP
SceS000002663
GO:0045721 negative regulation of gluconeogenesis P
IMP
SceS000002663
ISS
SpoSPBC29A3.03c

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