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Search term: YDR280W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RRP45
SGD link S000002688
Alternative ID YDR280W
Description Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp45p (PM/SCL-75, EXOSC9)
Synonyms YDR280W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1614 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Exosomal 3'-5' exoribonuclease complex, subunit Rrp45

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g12990 GI:18399822
Arabidopsis thaliana (Ath) At3g60500 GI:15232342
Caenorhabditis elegans (Cel) CE26424
(WBGene00018154)		 GI:17553318
Drosophila melanogaster (Dme) 7293284 GI:7293284
Homo sapiens (Hsa) Hs4826922 GI:4826922
Saccharomyces cerevisiae (Sce) YDR280w
(S000002688)		 GI:6320486 Q05636
Schizosaccharomyces pombe (Spo) SPCC757.08 GI:19075183 O74918
Encephalitozoon cuniculi (Ecu) ECU06g0390 GI:19074289 Q8SVE0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000002688
ISS
SpoSPCC757.08
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000002688
ISS
SpoSPCC757.08
GO:0005634 nucleus C
IDA
AthAt3g60500
At3g12990
SpoSPCC757.08
GO:0005730 nucleolus C
IDA
SceS000002688
GO:0005737 cytoplasm C
IDA
AthAt3g12990
At3g60500
GO:0005829 cytosol C
IDA
SpoSPCC757.08
GO:0000175 3'-5'-exoribonuclease activity F
IGI
AthAt3g60500
At3g12990
ISS
AthAt3g60500
At3g12990
SpoSPCC757.08
GO:0003674 molecular_function F
ND
SceS000002688
GO:0003723 RNA binding F
ISS
AthAt3g60500
At3g12990
GO:0000003 reproduction P
IMP
CelWBGene00018154
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000002688
GO:0002119 nematode larval development P
IMP
CelWBGene00018154
GO:0006364 rRNA processing P
ISS
SpoSPCC757.08
GO:0006396 RNA processing P
ISS
AthAt3g60500
At3g12990
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC757.08
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00018154
GO:0010025 wax biosynthetic process P
IGI
AthAt3g12990
IMP
AthAt3g60500
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000002688
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0040007 growth P
IMP
CelWBGene00018154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018154
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000002688
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000002688
GO:0070651 nonfunctional rRNA decay P
IC
SceS000002688
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000002688
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000002688
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000002688
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000002688

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3693

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EXOSC9 GI:77812670
Pan troglodytes (Ptr) EXOSC9 GI:114595906
Canis familiaris (Cfa) EXOSC9 GI:73983962
Mus musculus (Mmu) Exosc9
(MGI:1355319)		 GI:9506981 B2RY30
Rattus norvegicus (Rno) Exosc9
(RGD:1307888)		 GI:70794772
Gallus gallus (Gga) EXOSC9 GI:77797833
Drosophila melanogaster (Dme) Rrp45
(FBgn0030789)		 GI:24642649
Anopheles gambiae (Aga) AgaP_AGAP002348 GI:158291117
Caenorhabditis elegans (Cel) exos-9
(CE26424;
WBGene00018154)		 GI:25144570
Schizosaccharomyces pombe (Spo) SPCC757.08 GI:19075183 O74918
Saccharomyces cerevisiae (Sce) RRP45
(S000002688)		 GI:6320486 Q05636
Kluyveromyces lactis (Kla) KLLA0C11099g GI:50305471
Eremothecium gossypii (Ego) AGOS_AAL124W GI:45184700
Magnaporthe grisea (Mgr) MGG_08860 GI:145614266
Neurospora crassa (Ncr) NCU00334.1 GI:32403614
Arabidopsis thaliana (Ath) CER7 GI:15232342
Arabidopsis thaliana (Ath) RRP45a GI:79313209
Oryza sativa (Osa) Os02g0550700 GI:115446633
Plasmodium falciparum (Pfa) PF13_0340 GI:124514000


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000002688
ISS
DmeFBgn0030789
SpoSPCC757.08
NAS
HsaEXOSC9
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000002688
ISS
DmeFBgn0030789
SpoSPCC757.08
GO:0000178 exosome (RNase complex) C
ISS
DmeFBgn0030789
PfaPF13_0340
GO:0005634 nucleus C
IDA
AthCER7
RRP45a
SpoSPCC757.08
GO:0005730 nucleolus C
IDA
SceS000002688
TAS
MmuMGI:1355319
GO:0005737 cytoplasm C
IDA
AthRRP45a
CER7
GO:0005829 cytosol C
IDA
SpoSPCC757.08
GO:0000175 3'-5'-exoribonuclease activity F
IGI
AthRRP45a
CER7
ISS
AthRRP45a
CER7
DmeFBgn0030789
SpoSPCC757.08
NAS
HsaEXOSC9
GO:0003674 molecular_function F
ND
MmuMGI:1355319
SceS000002688
GO:0003723 RNA binding F
ISS
AthRRP45a
CER7
NAS
HsaEXOSC9
GO:0005515 protein binding F
IPI
HsaEXOSC9
GO:0000003 reproduction P
IMP
CelWBGene00018154
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000002688
GO:0002119 nematode larval development P
IMP
CelWBGene00018154
GO:0006364 rRNA processing P
ISS
SpoSPCC757.08
NAS
HsaEXOSC9
GO:0006396 RNA processing P
ISS
AthRRP45a
CER7
GO:0006397 mRNA processing P
ISS
DmeFBgn0030789
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC757.08
GO:0006955 immune response P
NAS
HsaEXOSC9
GO:0008150 biological_process P
ND
MmuMGI:1355319
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00018154
GO:0010025 wax biosynthetic process P
IGI
AthRRP45a
IMP
AthCER7
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000002688
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0040007 growth P
IMP
CelWBGene00018154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018154
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000002688
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000002688
GO:0070651 nonfunctional rRNA decay P
IC
SceS000002688
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000002688
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000002688
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000002688
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000002688

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1528

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4506 ENSANGP00000015425
Ashbya gossypii (Ago) ago63 AAL124W
Arabidopsis thaliana (Ath) ath13444 At3g12990.1
Arabidopsis thaliana (Ath) ath17480 At3g60500.1
Arabidopsis thaliana (Ath) ath17481 At3g60500.2
Caenorhabditis elegans (Cel) cel8412 F37C12.13a
(CE26424;
WBGene00018154)
Candida glabrata (Cgl) cgl3004 CAGL0J00275g
Cryptococcus neoformans (Cne) cne5335 179.m00186
Dictyostelium discoideum (Ddi) ddi2693 DDB0202891
Debaryomyces hansenii (Dha) dha1183 DEHA0B11682g
Drosophila melanogaster (Dme) dme18256 CG9606-PA
(FBgn0030789)
Danio rerio (Dre) dre377 ENSDARP00000005262
(zgc:101680)		 Q5XJQ5
Danio rerio (Dre) dre371 ENSDARP00000041454
Encephalitozoon cuniculi (Ecu) ecu1516 19074289
Takifugu rubripes (Fru) fru32870 SINFRUP00000140635
Gallus gallus (Gga) gga17845 ENSGALP00000019364
(EXOSC9)		 Q6B7Z6
Homo sapiens (Hsa) hsa24599 ENSP00000243498
(EXOSC9)		 Q06265-1
Homo sapiens (Hsa) hsa24598 ENSP00000349589
Kluyveromyces lactis (Kla) kla1694 KLLA0C11099g
Mus musculus (Mmu) mmu16513 ENSMUSP00000029269
(MGI:1355319)		 Q9JHI7
Neurospora crassa (Ncr) ncr320 NCU00334.2
Oryza sativa (Osa) osa81685 8224.m00022
Oryza sativa (Osa) osa81688 8224.m00027
Plasmodium falciparum (Pfa) pfa4446 PF13_0340
Rattus norvegicus (Rno) rno15950 ENSRNOP00000020662
(RGD:1307888)		 Q4QR75
Saccharomyces cerevisiae (Sce) sce1333 YDR280W
(S000002688)
Schizosaccharomyces pombe (Spo) spo4489 SPCC757.08 O74918
Yarrowia lipolytica (Yli) yli1089 YALI0B08514g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000002688
ISS
DmeFBgn0030789
SpoSPCC757.08
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000002688
ISS
DmeFBgn0030789
SpoSPCC757.08
GO:0000178 exosome (RNase complex) C
ISS
DmeFBgn0030789
PfaPF13_0340
GO:0005634 nucleus C
IDA
AthAt3g60500
At3g12990
SpoSPCC757.08
GO:0005730 nucleolus C
IDA
SceS000002688
TAS
MmuMGI:1355319
GO:0005737 cytoplasm C
IDA
AthAt3g12990
At3g60500
GO:0005829 cytosol C
IDA
SpoSPCC757.08
GO:0000175 3'-5'-exoribonuclease activity F
IGI
AthAt3g60500
At3g12990
ISS
AthAt3g60500
At3g12990
DmeFBgn0030789
SpoSPCC757.08
GO:0003674 molecular_function F
ND
MmuMGI:1355319
SceS000002688
GO:0003723 RNA binding F
ISS
AthAt3g60500
At3g12990
GO:0000003 reproduction P
IMP
CelWBGene00018154
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000002688
GO:0002119 nematode larval development P
IMP
CelWBGene00018154
GO:0006364 rRNA processing P
ISS
SpoSPCC757.08
GO:0006396 RNA processing P
ISS
AthAt3g60500
At3g12990
GO:0006397 mRNA processing P
ISS
DmeFBgn0030789
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC757.08
GO:0008150 biological_process P
ND
MmuMGI:1355319
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00018154
GO:0010025 wax biosynthetic process P
IGI
AthAt3g12990
IMP
AthAt3g60500
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000002688
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0040007 growth P
IMP
CelWBGene00018154
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018154
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000002688
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000002688
GO:0070651 nonfunctional rRNA decay P
IC
SceS000002688
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000002688
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000002688
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000002688
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000002688

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC757.08
(O74918)		 YDR280W
(S000002688)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000002688
ISS
SpoSPCC757.08
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000002688
ISS
SpoSPCC757.08
GO:0005634 nucleus C
IDA
SpoSPCC757.08
GO:0005730 nucleolus C
IDA
SceS000002688
GO:0005829 cytosol C
IDA
SpoSPCC757.08
GO:0000175 3'-5'-exoribonuclease activity F
ISS
SpoSPCC757.08
GO:0003674 molecular_function F
ND
SceS000002688
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000002688
GO:0006364 rRNA processing P
ISS
SpoSPCC757.08
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC757.08
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IC
SceS000002688
GO:0034473 U1 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034475 U4 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0034476 U5 snRNA 3'-end processing P
IGI
SceS000002688
IMP
SceS000002688
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000002688
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000002688
GO:0070651 nonfunctional rRNA decay P
IC
SceS000002688
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000002688
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000002688
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000002688
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000002688

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