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Search term: YDR284C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DPP1
SGD link S000002692
Alternative ID YDR284C
Description Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism
Synonyms YDR284C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3030 ACDHYPE

KOGs classification KOGs description
METABOLISM Lipid phosphate phosphatase and related enzymes of the PAP2 family

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g15080 GI:15218051
Arabidopsis thaliana (Ath) At2g01180 GI:15226192
Arabidopsis thaliana (Ath) At3g02600 GI:6957723
Arabidopsis thaliana (Ath) At3g18220 GI:15229598
Caenorhabditis elegans (Cel) CE02068
(WBGene00020895)		 GI:17536575
Caenorhabditis elegans (Cel) CE02324
(WBGene00011524)		 GI:17536067 Q22250
Caenorhabditis elegans (Cel) CE03202 GI:17551666
Caenorhabditis elegans (Cel) CE20846
(WBGene00018756)		 GI:17534293 Q9TXU1
Drosophila melanogaster (Dme) 7296544 GI:7296544
Drosophila melanogaster (Dme) 7296545 GI:7296545
Drosophila melanogaster (Dme) 7296546 GI:7296546
Drosophila melanogaster (Dme) 7296547 GI:7296547
Drosophila melanogaster (Dme) 7296548 GI:7296548
Drosophila melanogaster (Dme) 7296728 GI:7296728
Drosophila melanogaster (Dme) 7303896 GI:7303896
Drosophila melanogaster (Dme) 7303897 GI:7303897
Homo sapiens (Hsa) Hs12232395
(LPPR2)		 GI:12232395
Homo sapiens (Hsa) Hs13376339
(PRG2)		 GI:13376339 Q6T4P5
Homo sapiens (Hsa) Hs14210482 GI:14210482
Homo sapiens (Hsa) Hs14721243 GI:14721243
Homo sapiens (Hsa) Hs20474788 GI:20474788
Homo sapiens (Hsa) Hs21359834 GI:14327944 O14495
Homo sapiens (Hsa) Hs22041678 GI:22041678
Homo sapiens (Hsa) Hs22041680 GI:22041680
Homo sapiens (Hsa) Hs22053968 GI:22053968
Homo sapiens (Hsa) Hs4505973 GI:4505973
Homo sapiens (Hsa) Hs4505977
(PPAP2C)		 GI:4505977 O43688
Homo sapiens (Hsa) Hs8923281 GI:8923281
Homo sapiens (Hsa) HsM4505975 GI:4505975
Saccharomyces cerevisiae (Sce) YDR284c
(S000002692)		 GI:6320490 Q05521
Saccharomyces cerevisiae (Sce) YDR503c
(S000002911)		 GI:6320711 Q04396
Schizosaccharomyces pombe (Spo) SPBC409.18 GI:19112260 Q9UUA6
Encephalitozoon cuniculi (Ecu) ECU10g1440 GI:19074753 Q8SUB8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002692
ISS
SpoSPBC409.18
TAS
SceS000002692
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC409.18
GO:0005794 Golgi apparatus C
RCA
SceS000002911
GO:0005886 plasma membrane C
EXP
HsaPPAP2C
IDA
AthAt2g01180
At3g02600
At1g15080
GO:0005887 integral to plasma membrane C
ISS
AthAt1g15080
At3g02600
TAS
AthAt2g01180
GO:0016020 membrane C
IDA
SceS000002911
TAS
HsaPPAP2C
GO:0000810 diacylglycerol pyrophosphate phosphatase
activity		 F
IDA
SceS000002692
IMP
SceS000002692
ISS
SpoSPBC409.18
GO:0003993 acid phosphatase activity F
ISS
AthAt1g15080
GO:0004721 phosphoprotein phosphatase activity F
TAS
HsaPPAP2C
GO:0008195 phosphatidate phosphatase activity F
EXP
HsaPPAP2C
IDA
AthAt2g01180
At1g15080
SceS000002911
S000002692
ISS
AthAt2g01180
At3g18220
At3g02600
At1g15080
GO:0042392 sphingosine-1-phosphate phosphatase
activity		 F
EXP
HsaPPAP2C
GO:0006644 phospholipid metabolic process P
IMP
SceS000002911
S000002692
ISS
AthAt3g02600
SpoSPBC409.18
NAS
AthAt2g01180
GO:0006811 ion transport P
RCA
SceS000002692
GO:0006950 response to stress P
IEP
AthAt2g01180
GO:0007165 signal transduction P
TAS
SceS000002692
GO:0008150 biological_process P
ND
AthAt3g18220
GO:0009738 abscisic acid mediated signaling
pathway		 P
IGI
AthAt1g15080
GO:0019932 second-messenger-mediated signaling P
IC
SpoSPBC409.18
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00020895
GO:0050801 ion homeostasis P
RCA
SceS000002692

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101097

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC409.18 GI:19112260 Q9UUA6
Saccharomyces cerevisiae (Sce) DPP1
(S000002692)		 GI:6320490 Q05521
Kluyveromyces lactis (Kla) KLLA0C10835g GI:50305447
Eremothecium gossypii (Ego) AGOS_AAL084W GI:45184740
Magnaporthe grisea (Mgr) MGG_12462 GI:145612918
Neurospora crassa (Ncr) NCU05941.1 GI:32410631
Arabidopsis thaliana (Ath) LPP3 GI:145331736
Oryza sativa (Osa) Os01g0139600 GI:115434438


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002692
ISS
SpoSPBC409.18
TAS
SceS000002692
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC409.18
GO:0005886 plasma membrane C
IDA
AthLPP3
GO:0005887 integral to plasma membrane C
ISS
AthLPP3
GO:0009507 chloroplast C
IDA
AthLPP3
GO:0009532 plastid stroma C
IDA
AthLPP3
GO:0009534 chloroplast thylakoid C
IDA
AthLPP3
GO:0009570 chloroplast stroma C
IDA
AthLPP3
GO:0009840 chloroplastic endopeptidase Clp
complex		 C
IDA
AthLPP3
GO:0009941 chloroplast envelope C
IDA
AthLPP3
GO:0000810 diacylglycerol pyrophosphate phosphatase
activity		 F
IDA
SceS000002692
IMP
SceS000002692
ISS
SpoSPBC409.18
GO:0008195 phosphatidate phosphatase activity F
IDA
SceS000002692
ISS
AthLPP3
GO:0006644 phospholipid metabolic process P
IMP
SceS000002692
ISS
AthLPP3
SpoSPBC409.18
GO:0006811 ion transport P
RCA
SceS000002692
GO:0007165 signal transduction P
TAS
SceS000002692
GO:0019932 second-messenger-mediated signaling P
IC
SpoSPBC409.18
GO:0050801 ion homeostasis P
RCA
SceS000002692

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_801

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4041 ENSANGP00000019070
Ashbya gossypii (Ago) ago103 AAL084W
Arabidopsis thaliana (Ath) ath1602 At1g15080.1
Arabidopsis thaliana (Ath) ath7512 At2g01180.1
Arabidopsis thaliana (Ath) ath7513 At2g01180.2
Arabidopsis thaliana (Ath) ath12279 At3g02600.1
Arabidopsis thaliana (Ath) ath14085 At3g18220.1
Candida glabrata (Cgl) cgl2116 CAGL0H01177g
Cryptococcus neoformans (Cne) cne2469 181.m08509
Cryptococcus neoformans (Cne) cne2839 183.m01797
Dictyostelium discoideum (Ddi) ddi9831 DDB0185972
Debaryomyces hansenii (Dha) dha3878 DEHA0E14399g
Debaryomyces hansenii (Dha) dha3895 DEHA0E14773g
Debaryomyces hansenii (Dha) dha5153 DEHA0F17182g
Drosophila melanogaster (Dme) dme11042 CG12746-PA
(FBgn0037341)
Drosophila melanogaster (Dme) dme11040 CG12746-PB
(FBgn0037341)
Drosophila melanogaster (Dme) dme11043 CG12746-PC
(FBgn0037341)
Drosophila melanogaster (Dme) dme11041 CG12746-PD
(FBgn0037341)
Danio rerio (Dre) dre1783 ENSDARP00000010210
Encephalitozoon cuniculi (Ecu) ecu669 19074753
Takifugu rubripes (Fru) fru19385 SINFRUP00000153519
Takifugu rubripes (Fru) fru10080 SINFRUP00000154951
Gallus gallus (Gga) gga23942 ENSGALP00000005162
(PPAPDC1B)
Gallus gallus (Gga) gga20950 ENSGALP00000015401
(PPAPDC1A)
Homo sapiens (Hsa) hsa30186 ENSP00000276532
Homo sapiens (Hsa) hsa30185 ENSP00000314854
(PPAPDC1B)		 Q8NEB5-1
Kluyveromyces lactis (Kla) kla1682 KLLA0C10835g
Mus musculus (Mmu) mmu25781 ENSMUSP00000067035
(MGI:1919160)		 Q3UMZ3-1
Neurospora crassa (Ncr) ncr5775 NCU05941.2
Neurospora crassa (Ncr) ncr9436 NCU09692.2
Oryza sativa (Osa) osa8983 2689.m00109
Oryza sativa (Osa) osa12558 2826.m00126
Oryza sativa (Osa) osa32064 4399.m00170
Oryza sativa (Osa) osa50993 5926.m00171
Oryza sativa (Osa) osa56436 6389.m00159
Oryza sativa (Osa) osa56794 6396.m00162
Oryza sativa (Osa) osa58174 6458.m00155
Oryza sativa (Osa) osa58187 6458.m00322
Oryza sativa (Osa) osa58193 6458.m00323
Oryza sativa (Osa) osa78001 7480.m00150
Rattus norvegicus (Rno) rno12625 ENSRNOP00000020900
(RGD:1591734)
Rattus norvegicus (Rno) rno3085 ENSRNOP00000027681
(RGD:1306289)
Rattus norvegicus (Rno) rno3087 ENSRNOP00000042013
Saccharomyces cerevisiae (Sce) sce1337 YDR284C
(S000002692)
Schizosaccharomyces pombe (Spo) spo180 SPBC409.18 Q9UUA6
Yarrowia lipolytica (Yli) yli1341 YALI0B14531g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002692
ISS
SpoSPBC409.18
TAS
SceS000002692
GO:0005575 cellular_component C
ND
MmuMGI:1919160
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC409.18
GO:0005886 plasma membrane C
IDA
AthAt2g01180
At3g02600
At1g15080
GO:0005887 integral to plasma membrane C
ISS
AthAt1g15080
At3g02600
TAS
AthAt2g01180
GO:0000810 diacylglycerol pyrophosphate phosphatase
activity		 F
IDA
SceS000002692
IMP
SceS000002692
ISS
SpoSPBC409.18
GO:0003674 molecular_function F
ND
MmuMGI:1919160
GO:0003993 acid phosphatase activity F
ISS
AthAt1g15080
GO:0008195 phosphatidate phosphatase activity F
IDA
AthAt2g01180
At1g15080
SceS000002692
ISS
AthAt2g01180
At3g18220
At3g02600
At1g15080
DmeFBgn0037341
NAS
DmeFBgn0037341
GO:0006644 phospholipid metabolic process P
IMP
SceS000002692
ISS
AthAt3g02600
SpoSPBC409.18
NAS
AthAt2g01180
GO:0006811 ion transport P
RCA
SceS000002692
GO:0006950 response to stress P
IEP
AthAt2g01180
GO:0007165 signal transduction P
TAS
SceS000002692
GO:0008150 biological_process P
ND
AthAt3g18220
MmuMGI:1919160
GO:0009738 abscisic acid mediated signaling
pathway		 P
IGI
AthAt1g15080
GO:0016311 dephosphorylation P
NAS
DmeFBgn0037341
GO:0019932 second-messenger-mediated signaling P
IC
SpoSPBC409.18
GO:0050801 ion homeostasis P
RCA
SceS000002692

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC409.18
(Q9UUA6)		 YDR284C
(S000002692)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000329 fungal-type vacuole membrane C
IDA
SceS000002692
ISS
SpoSPBC409.18
TAS
SceS000002692
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC409.18
GO:0000810 diacylglycerol pyrophosphate phosphatase
activity		 F
IDA
SceS000002692
IMP
SceS000002692
ISS
SpoSPBC409.18
GO:0008195 phosphatidate phosphatase activity F
IDA
SceS000002692
GO:0006644 phospholipid metabolic process P
IMP
SceS000002692
ISS
SpoSPBC409.18
GO:0006811 ion transport P
RCA
SceS000002692
GO:0007165 signal transduction P
TAS
SceS000002692
GO:0019932 second-messenger-mediated signaling P
IC
SpoSPBC409.18
GO:0050801 ion homeostasis P
RCA
SceS000002692

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