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Search term: YDR288W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NSE3
SGD link S000002696
Alternative ID YDR288W
Description Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for DNA repair and growth
Synonyms YDR288W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4562 A--HYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein (tumor-rejection antigen MAGE in humans)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g34770 GI:15218767
Homo sapiens (Hsa) Hs10567820 GI:10567820 P43363
Homo sapiens (Hsa) Hs11545892 GI:11545892
Homo sapiens (Hsa) Hs13647867 GI:13647867
Homo sapiens (Hsa) Hs14195634 GI:14195634
Homo sapiens (Hsa) Hs15042941
(MAGEH1)		 GI:15042941 Q9H213
Homo sapiens (Hsa) Hs17459095 GI:17459095
Homo sapiens (Hsa) Hs17459115 GI:17459115
Homo sapiens (Hsa) Hs17459315 GI:17459315
Homo sapiens (Hsa) Hs17459317 GI:17459317
Homo sapiens (Hsa) Hs17485686 GI:17485686
Homo sapiens (Hsa) Hs17486103 GI:17486103
Homo sapiens (Hsa) Hs17486564 GI:17486564
Homo sapiens (Hsa) Hs19387846 GI:10863907
Homo sapiens (Hsa) Hs19923308
(MAGEA8)		 GI:19923308 P43361
Homo sapiens (Hsa) Hs19923734 GI:19923734
Homo sapiens (Hsa) Hs20143482
(MAGEE1)		 GI:20143482 Q9HCI5
Homo sapiens (Hsa) Hs20162568 GI:17459335
Homo sapiens (Hsa) Hs20162570 GI:17486185
Homo sapiens (Hsa) Hs20162572
(NDNL2)		 GI:20162572 Q96MG7
Homo sapiens (Hsa) Hs20547686 GI:20547686
Homo sapiens (Hsa) Hs20548228 GI:20548228
Homo sapiens (Hsa) Hs20550717_1 GI:20550717
Homo sapiens (Hsa) Hs20550968 GI:20550968
Homo sapiens (Hsa) Hs20551038 GI:20551038
Homo sapiens (Hsa) Hs20551260 GI:20551260
Homo sapiens (Hsa) Hs20551307 GI:20551307
Homo sapiens (Hsa) Hs20553203 GI:20553203
Homo sapiens (Hsa) Hs21359869 GI:17028469 P43355
Homo sapiens (Hsa) Hs22057325 GI:22057325
Homo sapiens (Hsa) Hs22057466 GI:22057466
Homo sapiens (Hsa) Hs4505079 GI:4505079
Homo sapiens (Hsa) Hs4505081 GI:4505081
Homo sapiens (Hsa) Hs4505083 GI:4505083
Homo sapiens (Hsa) Hs4505085
(MAGEB4)		 GI:4505085 O15481
Homo sapiens (Hsa) Hs4505349
(NDN)		 GI:4505349 Q99608
Homo sapiens (Hsa) Hs4885461 GI:4885461
Homo sapiens (Hsa) Hs4885463 GI:4885463
Homo sapiens (Hsa) Hs4885465 GI:4885465 P43356
Homo sapiens (Hsa) Hs4885467
(MAGEA3)		 GI:4885467 P43357
Homo sapiens (Hsa) Hs4885469
(MAGEA6)		 GI:4885469 P43360
Homo sapiens (Hsa) Hs4885473
(MAGEA9)		 GI:4885473 P43362
Homo sapiens (Hsa) Hs4885475 GI:4885475
Homo sapiens (Hsa) Hs7705566 GI:7705566
Homo sapiens (Hsa) Hs7706605
(MAGEC2)		 GI:7706605 Q9UBF1
Homo sapiens (Hsa) Hs9506925 GI:9506925
Homo sapiens (Hsa) HsM4826822 GI:4826822
Saccharomyces cerevisiae (Sce) YDR288w
(S000002696)		 GI:6320494 Q05541
Schizosaccharomyces pombe (Spo) SPCC645.04 GI:19075613 Q9Y7U4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g34770
HsaMAGEA6
MAGEA9
MAGEA8
GO:0005634 nucleus C
IDA
HsaMAGEC2
SceS000002696
SpoSPCC645.04
ISS
HsaMAGEE1
TAS
SpoSPCC645.04
GO:0005737 cytoplasm C
IDA
HsaMAGEC2
SceS000002696
GO:0005886 plasma membrane C
ISS
HsaMAGEE1
GO:0016010 dystrophin-associated glycoprotein
complex		 C
ISS
HsaMAGEE1
GO:0030425 dendrite C
ISS
HsaMAGEE1
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000002696
SpoSPCC645.04
GO:0045211 postsynaptic membrane C
ISS
HsaMAGEE1
GO:0048471 perinuclear region of cytoplasm C
ISS
HsaMAGEE1
GO:0003674 molecular_function F
ND
AthAt1g34770
HsaMAGEA6
MAGEA9
MAGEA8
GO:0003677 DNA binding F
ISS
SceS000002696
GO:0005515 protein binding F
IPI
HsaNDN
MAGEA6
SpoSPCC645.04
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPCC645.04
GO:0000706 meiotic DNA double-strand break
processing		 P
IDA
SpoSPCC645.04
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPCC645.04
GO:0006281 DNA repair P
IMP
SceS000002696
IPI
SceS000002696
GO:0006915 apoptosis P
TAS
HsaMAGEH1
GO:0007399 nervous system development P
TAS
HsaNDN
GO:0008150 biological_process P
ND
AthAt1g34770
HsaMAGEE1
MAGEA8
MAGEA9
MAGEA6
GO:0008285 negative regulation of cell proliferation P
TAS
HsaNDN
GO:0048478 replication fork protection P
IGI
SpoSPCC645.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38752

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) NSE3
(S000002696)		 GI:6320494 Q05541
Kluyveromyces lactis (Kla) KLLA0D08734g GI:50306953
Eremothecium gossypii (Ego) AGOS_AAL120C GI:45184704


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002696
GO:0005737 cytoplasm C
IDA
SceS000002696
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000002696
GO:0003677 DNA binding F
ISS
SceS000002696
GO:0006281 DNA repair P
IMP
SceS000002696
IPI
SceS000002696

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24585

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago67 AAL120C
Candida glabrata (Cgl) cgl2111 CAGL0H01067g
Debaryomyces hansenii (Dha) dha6536 DEHA0G18711g
Kluyveromyces lactis (Kla) kla2451 KLLA0D08734g
Saccharomyces cerevisiae (Sce) sce1341 YDR288W
(S000002696)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002696
GO:0005737 cytoplasm C
IDA
SceS000002696
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000002696
GO:0003677 DNA binding F
ISS
SceS000002696
GO:0006281 DNA repair P
IMP
SceS000002696
IPI
SceS000002696

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC645.04
(Q9Y7U4)		 YDR288W
(S000002696)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002696
SpoSPCC645.04
TAS
SpoSPCC645.04
GO:0005737 cytoplasm C
IDA
SceS000002696
GO:0030915 Smc5-Smc6 complex C
IPI
SceS000002696
SpoSPCC645.04
GO:0003677 DNA binding F
ISS
SceS000002696
GO:0005515 protein binding F
IPI
SpoSPCC645.04
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPCC645.04
GO:0000706 meiotic DNA double-strand break
processing		 P
IDA
SpoSPCC645.04
GO:0000724 double-strand break repair via homologous
recombination		 P
IGI
SpoSPCC645.04
GO:0006281 DNA repair P
IMP
SceS000002696
IPI
SceS000002696
GO:0048478 replication fork protection P
IGI
SpoSPCC645.04

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