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Search term: YDR293C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SSD1
SGD link S000002701
Alternative ID YDR293C
Description Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence
Synonyms YDR293C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2102 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g77680 GI:15220899
Arabidopsis thaliana (Ath) At2g17510 GI:15227854
Arabidopsis thaliana (Ath) At5g02250 GI:15241738
Caenorhabditis elegans (Cel) CE02758
(WBGene00018612)		 GI:17553506 Q09568
Caenorhabditis elegans (Cel) CE05214
(WBGene00001001)		 GI:17538438
Drosophila melanogaster (Dme) 7291934 GI:7291934
Drosophila melanogaster (Dme) 7301148 GI:18488261
Homo sapiens (Hsa) Hs14769950_2 GI:14769950
Homo sapiens (Hsa) Hs19115966 GI:19115966 Q8TF46
Homo sapiens (Hsa) Hs19923416 GI:19923416
Homo sapiens (Hsa) Hs20537912 GI:20537912
Homo sapiens (Hsa) Hs21703358_2 GI:21703358
Homo sapiens (Hsa) Hs22045556 GI:22045556
Saccharomyces cerevisiae (Sce) YDR293c
(S000002701)		 GI:6320499 P24276
Saccharomyces cerevisiae (Sce) YMR287c
(S000004900)		 GI:6323943 P39112
Saccharomyces cerevisiae (Sce) YOL021c
(S000005381)		 GI:6324552 Q08162
Schizosaccharomyces pombe (Spo) SPAC2C4.07c GI:19115422 O14040
Schizosaccharomyces pombe (Spo) SPBC26H8.10 GI:19113445 P37202
Schizosaccharomyces pombe (Spo) SPBC609.01 GI:19113103 O94525
Schizosaccharomyces pombe (Spo) SPCC16C4.09 GI:19075419 O74454
Schizosaccharomyces pombe (Spo) SPCC23B6.06 GI:19075629
Encephalitozoon cuniculi (Ecu) ECU03g0700 GI:19173030 Q8SW47


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
IDA
SceS000005381
ISS
SpoSPBC26H8.10
GO:0000177 cytoplasmic exosome (RNase complex) C
IDA
SceS000005381
ISS
SpoSPBC26H8.10
GO:0005634 nucleus C
IDA
SpoSPBC26H8.10
GO:0005730 nucleolus C
IDA
SceS000005381
GO:0005737 cytoplasm C
IDA
SceS000002701
SpoSPAC2C4.07c
SPBC609.01
SPCC16C4.09
GO:0005739 mitochondrion C
IDA
AthAt5g02250
SceS000004900
S000005381
ISS
SpoSPBC26H8.10
GO:0005759 mitochondrial matrix C
IDA
SceS000004900
GO:0005829 cytosol C
IDA
SpoSPAC2C4.07c
SPBC609.01
SPCC16C4.09
GO:0009507 chloroplast C
IDA
AthAt5g02250
GO:0032153 cell division site C
IDA
SpoSPCC16C4.09
GO:0000049 tRNA binding F
IDA
SceS000005381
IMP
SceS000005381
GO:0000175 3'-5'-exoribonuclease activity F
IDA
AthAt5g02250
SceS000005381
IMP
SceS000005381
ISS
SpoSPBC26H8.10
GO:0003723 RNA binding F
IDA
SceS000002701
ISS
AthAt2g17510
At5g02250
At1g77680
SpoSPAC2C4.07c
SPCC16C4.09
SPBC609.01
GO:0003729 mRNA binding F
IDA
SceS000002701
GO:0004518 nuclease activity F
RCA
SceS000002701
GO:0004521 endoribonuclease activity F
IDA
SceS000005381
IMP
SceS000005381
GO:0004527 exonuclease activity F
RCA
SceS000002701
GO:0004532 exoribonuclease activity F
RCA
SceS000002701
GO:0004540 ribonuclease activity F
ISS
AthAt1g77680
At5g02250
At2g17510
SpoSPBC609.01
SPAC2C4.07c
SPCC16C4.09
GO:0005515 protein binding F
IPI
SpoSPBC26H8.10
GO:0008408 3'-5' exonuclease activity F
RCA
SceS000002701
GO:0008536 Ran GTPase binding F
IPI
SpoSPBC26H8.10
GO:0008859 exoribonuclease II activity F
IDA
SceS000004900
GO:0016788 hydrolase activity, acting on ester
bonds		 F
RCA
SceS000002701
GO:0016796 exonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0016896 exoribonuclease activity, producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0000003 reproduction P
IMP
CelWBGene00001001
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPBC26H8.10
GO:0000465 exonucleolytic trimming to generate mature 5'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
ISS
SpoSPBC26H8.10
GO:0000467 exonucleolytic trimming to generate mature 3'-end
of 5.8S rRNA from tricistronic rRNA transcript
(SSU-rRNA, 5.8S rRNA, LSU-rRNA)		 P
IMP
SceS000005381
GO:0001300 chronological cell aging P
IMP
SceS000002701
GO:0001302 replicative cell aging P
IMP
SceS000002701
GO:0006364 rRNA processing P
IMP
AthAt5g02250
GO:0006401 RNA catabolic process P
IDA
SceS000004900
IMP
SceS000004900
ISS
SpoSPAC2C4.07c
SPCC16C4.09
GO:0006402 mRNA catabolic process P
ISS
SpoSPBC26H8.10
GO:0007051 spindle organization P
IMP
SpoSPBC26H8.10
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPBC26H8.10
GO:0008150 biological_process P
ND
SpoSPBC609.01
GO:0009658 chloroplast organization P
IMP
AthAt5g02250
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g02250
GO:0009826 unidimensional cell growth P
IMP
SpoSPCC16C4.09
GO:0016073 snRNA metabolic process P
RCA
SceS000005381
GO:0016075 rRNA catabolic process P
IMP
SceS000005381
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002701
GO:0032853 positive regulation of Ran GTPase
activity		 P
IMP
SpoSPBC26H8.10
GO:0033554 cellular response to stress P
IEP
SpoSPAC2C4.07c
GO:0034475 U4 snRNA 3'-end processing P
RCA
SceS000005381
GO:0034613 cellular protein localization P
IGI
SpoSPCC16C4.09
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001001
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001001
GO:0043144 snoRNA processing P
RCA
SceS000005381
GO:0043628 ncRNA 3'-end processing P
IMP
SceS000005381
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IC
SceS000005381
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IC
SceS000005381
GO:0070651 nonfunctional rRNA decay P
IMP
SceS000005381
GO:0071028 nuclear mRNA surveillance P
IMP
SceS000005381
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic
process		 P
IMP
SceS000005381
GO:0071038 nuclear polyadenylation-dependent tRNA catabolic
process		 P
IDA
SceS000005381
IGI
SceS000005381
IMP
SceS000005381
GO:0071039 nuclear polyadenylation-dependent CUT catabolic
process		 P
IMP
SceS000005381
GO:0071042 nuclear polyadenylation-dependent mRNA catabolic
process		 P
IC
SceS000005381
GO:0071051 polyadenylation-dependent snoRNA 3'-end
processing		 P
IC
SceS000005381

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68649

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SSD1
(S000002701)		 GI:6320499 P24276
Kluyveromyces lactis (Kla) KLLA0C10571g GI:50305423
Eremothecium gossypii (Ego) AGOS_AAL072C GI:45184752
Magnaporthe grisea (Mgr) MGG_08084 GI:145612079
Neurospora crassa (Ncr) NCU01197.1 GI:32412420


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002701
GO:0003723 RNA binding F
IDA
SceS000002701
GO:0003729 mRNA binding F
IDA
SceS000002701
GO:0004518 nuclease activity F
RCA
SceS000002701
GO:0004527 exonuclease activity F
RCA
SceS000002701
GO:0004532 exoribonuclease activity F
RCA
SceS000002701
GO:0008408 3'-5' exonuclease activity F
RCA
SceS000002701
GO:0016788 hydrolase activity, acting on ester
bonds		 F
RCA
SceS000002701
GO:0016796 exonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0016896 exoribonuclease activity, producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0001300 chronological cell aging P
IMP
SceS000002701
GO:0001302 replicative cell aging P
IMP
SceS000002701
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002701

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2741

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago115 AAL072C
Arabidopsis thaliana (Ath) ath7108 At1g77680.1
Caenorhabditis elegans (Cel) cel9627 F48E8.6
(CE02758;
WBGene00018612)
Candida glabrata (Cgl) cgl2121 CAGL0H01287g
Cryptococcus neoformans (Cne) cne4321 177.m03076
Dictyostelium discoideum (Ddi) ddi5864 DDB0206173
Debaryomyces hansenii (Dha) dha6665 DEHA0G21615g
Drosophila melanogaster (Dme) dme7198 CG16940-PA
(FBgn0035111)
Drosophila melanogaster (Dme) dme7196 CG16940-PB
(FBgn0035111)
Drosophila melanogaster (Dme) dme7197 CG16940-PC
(FBgn0035111)
Danio rerio (Dre) dre29964 ENSDARP00000040097
Takifugu rubripes (Fru) fru27568 SINFRUP00000140976
Gallus gallus (Gga) gga23539 ENSGALP00000012585
(DIS3L2)
Gallus gallus (Gga) gga23540 ENSGALP00000012586
Homo sapiens (Hsa) hsa19463 ENSP00000273009
(DIS3L2)		 Q8IYB7-3
Homo sapiens (Hsa) hsa19464 ENSP00000315569
(DIS3L2)		 Q8IYB7-1
Kluyveromyces lactis (Kla) kla1670 KLLA0C10571g
Mus musculus (Mmu) mmu696 ENSMUSP00000068384
(MGI:2442555)		 Q8C0W5
Mus musculus (Mmu) mmu697 ENSMUSP00000070506
(MGI:2442555)		 Q8CI75-1
Neurospora crassa (Ncr) ncr1160 NCU01197.2
Oryza sativa (Osa) osa30056 4341.m00197
Rattus norvegicus (Rno) rno30397 ENSRNOP00000025779
(RGD:1560168)
Saccharomyces cerevisiae (Sce) sce1346 YDR293C
(S000002701)
Schizosaccharomyces pombe (Spo) spo4822 SPAC2C4.07c O14040
Schizosaccharomyces pombe (Spo) spo2587 SPBC609.01 O94525
Schizosaccharomyces pombe (Spo) spo1728 SPCC16C4.09 O74454
Yarrowia lipolytica (Yli) yli5921 YALI0F13717g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000176 nuclear exosome (RNase complex) C
ISS
DmeFBgn0035111
GO:0000177 cytoplasmic exosome (RNase complex) C
ISS
DmeFBgn0035111
GO:0005575 cellular_component C
ND
MmuMGI:2442555
GO:0005737 cytoplasm C
IDA
SceS000002701
SpoSPAC2C4.07c
SPBC609.01
SPCC16C4.09
GO:0005829 cytosol C
IDA
SpoSPAC2C4.07c
SPBC609.01
SPCC16C4.09
GO:0032153 cell division site C
IDA
SpoSPCC16C4.09
GO:0003674 molecular_function F
ND
MmuMGI:2442555
GO:0003723 RNA binding F
IDA
SceS000002701
ISS
AthAt1g77680
SpoSPAC2C4.07c
SPCC16C4.09
SPBC609.01
GO:0003729 mRNA binding F
IDA
SceS000002701
GO:0004518 nuclease activity F
RCA
SceS000002701
GO:0004527 exonuclease activity F
RCA
SceS000002701
GO:0004532 exoribonuclease activity F
RCA
SceS000002701
GO:0004540 ribonuclease activity F
ISS
AthAt1g77680
SpoSPBC609.01
SPAC2C4.07c
SPCC16C4.09
GO:0008408 3'-5' exonuclease activity F
RCA
SceS000002701
GO:0008859 exoribonuclease II activity F
ISS
DmeFBgn0035111
GO:0016788 hydrolase activity, acting on ester
bonds		 F
RCA
SceS000002701
GO:0016796 exonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0016896 exoribonuclease activity, producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0001300 chronological cell aging P
IMP
SceS000002701
GO:0001302 replicative cell aging P
IMP
SceS000002701
GO:0006401 RNA catabolic process P
ISS
SpoSPAC2C4.07c
SPCC16C4.09
GO:0008150 biological_process P
ND
MmuMGI:2442555
SpoSPBC609.01
GO:0009826 unidimensional cell growth P
IMP
SpoSPCC16C4.09
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002701
GO:0033554 cellular response to stress P
IEP
SpoSPAC2C4.07c
GO:0034613 cellular protein localization P
IGI
SpoSPCC16C4.09

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC16C4.09
(O74454)		 YDR293C
(S000002701)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002701
SpoSPCC16C4.09
GO:0005829 cytosol C
IDA
SpoSPCC16C4.09
GO:0032153 cell division site C
IDA
SpoSPCC16C4.09
GO:0003723 RNA binding F
IDA
SceS000002701
ISS
SpoSPCC16C4.09
GO:0003729 mRNA binding F
IDA
SceS000002701
GO:0004518 nuclease activity F
RCA
SceS000002701
GO:0004527 exonuclease activity F
RCA
SceS000002701
GO:0004532 exoribonuclease activity F
RCA
SceS000002701
GO:0004540 ribonuclease activity F
ISS
SpoSPCC16C4.09
GO:0008408 3'-5' exonuclease activity F
RCA
SceS000002701
GO:0016788 hydrolase activity, acting on ester
bonds		 F
RCA
SceS000002701
GO:0016796 exonuclease activity, active with either ribo- or
deoxyribonucleic acids and producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0016896 exoribonuclease activity, producing
5'-phosphomonoesters		 F
RCA
SceS000002701
GO:0001300 chronological cell aging P
IMP
SceS000002701
GO:0001302 replicative cell aging P
IMP
SceS000002701
GO:0006401 RNA catabolic process P
ISS
SpoSPCC16C4.09
GO:0009826 unidimensional cell growth P
IMP
SpoSPCC16C4.09
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002701
GO:0034613 cellular protein localization P
IGI
SpoSPCC16C4.09

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