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Search term: YDR295C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HDA2
SGD link S000002703
Alternative ID YDR295C
Description Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance
Synonyms YDR295C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38754

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HDA2
(S000002703)
GI:6320501
Kluyveromyces lactis (Kla) KLLA0C10483g GI:50305415
Eremothecium gossypii (Ego) AGOS_AAL069C GI:45184755


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002703
GO:0070823 HDA1 complex C
IDA
SceS000002703
IPI
SceS000002703
GO:0003677 DNA binding F
IDA
SceS000002703
GO:0003682 chromatin binding F
IDA
SceS000002703
GO:0004407 histone deacetylase activity F
IDA
SceS000002703
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002703
GO:0010978 gene silencing involved in chronological cell
aging
P
IGI
SceS000002703
IMP
SceS000002703
GO:0016575 histone deacetylation P
IDA
SceS000002703
IMP
SceS000002703
GO:0031047 gene silencing by RNA P
IMP
SceS000002703

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24799

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago118 AAL069C
Candida glabrata (Cgl) cgl2123 CAGL0H01331g
Debaryomyces hansenii (Dha) dha3090 DEHA0D17611g
Kluyveromyces lactis (Kla) kla1666 KLLA0C10483g
Saccharomyces cerevisiae (Sce) sce1348 YDR295C
(S000002703)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002703
GO:0070823 HDA1 complex C
IDA
SceS000002703
IPI
SceS000002703
GO:0003677 DNA binding F
IDA
SceS000002703
GO:0003682 chromatin binding F
IDA
SceS000002703
GO:0004407 histone deacetylase activity F
IDA
SceS000002703
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002703
GO:0010978 gene silencing involved in chronological cell
aging
P
IGI
SceS000002703
IMP
SceS000002703
GO:0016575 histone deacetylation P
IDA
SceS000002703
IMP
SceS000002703
GO:0031047 gene silencing by RNA P
IMP
SceS000002703

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC188.07
(Q10432)
YDR295C
(S000002703)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPCC188.07
GO:0005634 nucleus C
IDA
SceS000002703
SpoSPCC188.07
GO:0005654 nucleoplasm C
IDA
SpoSPCC188.07
GO:0005816 spindle pole body C
IDA
SpoSPCC188.07
GO:0031933 telomeric heterochromatin C
IDA
SpoSPCC188.07
GO:0043234 protein complex C
NAS
SpoSPCC188.07
GO:0070188 Stn1-Ten1 complex C
IDA
SpoSPCC188.07
GO:0070823 HDA1 complex C
IDA
SceS000002703
IPI
SceS000002703
GO:0003677 DNA binding F
IDA
SceS000002703
GO:0003682 chromatin binding F
IDA
SceS000002703
GO:0004407 histone deacetylase activity F
IDA
SceS000002703
GO:0005515 protein binding F
IPI
SpoSPCC188.07
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002703
GO:0000723 telomere maintenance P
IMP
SpoSPCC188.07
GO:0006348 chromatin silencing at telomere P
IMP
SpoSPCC188.07
GO:0010978 gene silencing involved in chronological cell
aging
P
IGI
SceS000002703
IMP
SceS000002703
GO:0016233 telomere capping P
IGI
SpoSPCC188.07
GO:0016575 histone deacetylation P
IDA
SceS000002703
IMP
SceS000002703
GO:0031047 gene silencing by RNA P
IMP
SceS000002703
GO:0032206 positive regulation of telomere
maintenance
P
IMP
SpoSPCC188.07
GO:0034613 cellular protein localization P
IGI
SpoSPCC188.07
GO:0045132 meiotic chromosome segregation P
IMP
SpoSPCC188.07
GO:0045141 meiotic telomere clustering P
IMP
SpoSPCC188.07
GO:0048239 negative regulation of DNA recombination at
telomere
P
IMP
SpoSPCC188.07

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