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Search term: YDR308C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SRB7
SGD link S000002716
Alternative ID YDR308C
Description Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p
Synonyms YDR308C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1510 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA polymerase II holoenzyme and mediator subcomplex, subunit SURB7/SRB7

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g04780_2 GI:15234448
Caenorhabditis elegans (Cel) CE18529_2 GI:17552292
Drosophila melanogaster (Dme) 7289569 GI:7289569
Homo sapiens (Hsa) Hs21361161 GI:7531204 Q13503
Homo sapiens (Hsa) HsM4759194 GI:4759194
Saccharomyces cerevisiae (Sce) YDR308c
(S000002716)
GI:6320514 P47822
Schizosaccharomyces pombe (Spo) SPBC1604.10 GI:19113422 O94376


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC1604.10
GO:0005829 cytosol C
IDA
SpoSPBC1604.10
GO:0016592 mediator complex C
IDA
SceS000002716
SpoSPBC1604.10
NAS
SpoSPBC1604.10
TAS
AthAt4g04780
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0009817 defense response to fungus, incompatible
interaction
P
IMP
AthAt4g04780
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPBC1604.10
GO:0045449 regulation of transcription P
ISS
SpoSPBC1604.10
TAS
AthAt4g04780

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38762

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SRB7
(S000002716)
GI:6320514 P47822
Kluyveromyces lactis (Kla) KLLA0C14806g GI:50305805
Eremothecium gossypii (Ego) AGOS_AAL049C GI:45184775


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0016592 mediator complex C
IDA
SceS000002716
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000002716
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000002716

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15299

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago138 AAL049C
Candida glabrata (Cgl) cgl3476 CAGL0J11022g
Debaryomyces hansenii (Dha) dha3619 DEHA0E08547g
Kluyveromyces lactis (Kla) kla1862 KLLA0C14806g
Neurospora crassa (Ncr) ncr5108 NCU05263.2
Saccharomyces cerevisiae (Sce) sce1361 YDR308C
(S000002716)
Schizosaccharomyces pombe (Spo) spo4017 SPBC1604.10 O94376
Yarrowia lipolytica (Yli) yli4480 YALI0E15037g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC1604.10
GO:0005829 cytosol C
IDA
SpoSPBC1604.10
GO:0016592 mediator complex C
IDA
SceS000002716
SpoSPBC1604.10
NAS
SpoSPBC1604.10
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPBC1604.10
GO:0045449 regulation of transcription P
ISS
SpoSPBC1604.10

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC1604.10
(O94376)
YDR308C
(S000002716)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC1604.10
GO:0005829 cytosol C
IDA
SpoSPBC1604.10
GO:0016592 mediator complex C
IDA
SceS000002716
SpoSPBC1604.10
NAS
SpoSPBC1604.10
GO:0016455 RNA polymerase II transcription mediator
activity
F
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0006366 transcription from RNA polymerase II
promoter
P
IDA
SceS000002716
ISS
SpoSPBC1604.10
GO:0032569 gene-specific transcription from RNA polymerase II
promoter
P
IC
SpoSPBC1604.10
GO:0045449 regulation of transcription P
ISS
SpoSPBC1604.10

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