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Search term: YDR331W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GPI8
SGD link S000002739
Alternative ID YDR331W
Description ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog
Synonyms YDR331W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1349 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Gpi-anchor transamidase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g08750 GI:15223905
Caenorhabditis elegans (Cel) CE13247 GI:17542212
Drosophila melanogaster (Dme) 7290241 GI:7290241
Homo sapiens (Hsa) Hs14724559 GI:14724559
Saccharomyces cerevisiae (Sce) YDR331w
(S000002739)
GI:6320538 P49018
Schizosaccharomyces pombe (Spo) SPCC11E10.02c GI:19075698 Q9USP5
Encephalitozoon cuniculi (Ecu) ECU09g1070 GI:19173230


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC11E10.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002739
GO:0042765 GPI-anchor transamidase complex C
IGI
SpoSPCC11E10.02c
IPI
SceS000002739
GO:0003923 GPI-anchor transamidase activity F
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
IPI
SceS000002739
ISS
AthAt1g08750
GO:0004197 cysteine-type endopeptidase activity F
ISS
SpoSPCC11E10.02c
GO:0006508 proteolysis P
ISS
AthAt1g08750
GO:0016255 attachment of GPI anchor to protein P
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
GO:0042157 lipoprotein metabolic process P
RCA
SceS000002739

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4002

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PIGK GI:23199983
Pan troglodytes (Ptr) PIGK GI:114557239
Canis familiaris (Cfa) PIGK GI:73959812
Mus musculus (Mmu) Pigk
(MGI:1913863)
GI:29788753 Q3TGN0
Rattus norvegicus (Rno) Pigk
(RGD:1306753)
GI:58865476
Gallus gallus (Gga) PIGK GI:71896773
Drosophila melanogaster (Dme) CG4406
(FBgn0023545)
GI:24639234
Anopheles gambiae (Aga) AgaP_AGAP004301 GI:158292002
Caenorhabditis elegans (Cel) T05E11.6
(CE40776;
WBGene00011482)
GI:193206557
Schizosaccharomyces pombe (Spo) gpi8
(SPCC11E10.02c)
GI:19075698 Q9USP5
Saccharomyces cerevisiae (Sce) GPI8
(S000002739)
GI:6320538 P49018
Kluyveromyces lactis (Kla) KLLA0E17105g GI:50309421
Eremothecium gossypii (Ego) AGOS_ADR299W GI:45188173
Magnaporthe grisea (Mgr) MGG_10490 GI:39969761
Neurospora crassa (Ncr) NCU07259.1 GI:32414131
Arabidopsis thaliana (Ath) AT1G08750 GI:18390936
Oryza sativa (Osa) Os02g0219400 GI:115445065


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1913863
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC11E10.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002739
GO:0030176 integral to endoplasmic reticulum
membrane
C
NAS
HsaPIGK
GO:0042765 GPI-anchor transamidase complex C
IGI
SpoSPCC11E10.02c
IMP
HsaPIGK
IPI
SceS000002739
GO:0003674 molecular_function F
ND
MmuMGI:1913863
GO:0003923 GPI-anchor transamidase activity F
IGI
SpoSPCC11E10.02c
IMP
HsaPIGK
SceS000002739
IPI
SceS000002739
ISS
AthAt1g08750
DmeFBgn0023545
GO:0004197 cysteine-type endopeptidase activity F
ISS
SpoSPCC11E10.02c
GO:0005515 protein binding F
IPI
HsaPIGK
GO:0034235 GPI anchor binding F
TAS
HsaPIGK
GO:0000003 reproduction P
IMP
CelWBGene00011482
GO:0006467 protein thiol-disulfide exchange P
TAS
HsaPIGK
GO:0006508 proteolysis P
ISS
AthAt1g08750
GO:0008150 biological_process P
ND
MmuMGI:1913863
GO:0016255 attachment of GPI anchor to protein P
EXP
HsaPIGK
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
TAS
HsaPIGK
GO:0042157 lipoprotein metabolic process P
RCA
SceS000002739

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1808

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6841 ENSANGP00000013498
Ashbya gossypii (Ago) ago2041 ADR299W
Arabidopsis thaliana (Ath) ath884 At1g08750.1
Arabidopsis thaliana (Ath) ath885 At1g08750.2
Arabidopsis thaliana (Ath) ath886 At1g08750.3
Caenorhabditis elegans (Cel) cel14642 T05E11.6
(CE40776;
WBGene00011482)
Candida glabrata (Cgl) cgl4711 CAGL0M01298g
Cryptococcus neoformans (Cne) cne1463 180.m00417
Dictyostelium discoideum (Ddi) ddi8681 DDB0186511
Debaryomyces hansenii (Dha) dha5611 DEHA0F27401g
Drosophila melanogaster (Dme) dme16157 CG4406-PA
(FBgn0023545)
Danio rerio (Dre) dre10830 ENSDARP00000039104
(pigk)
Q6IQM5
Danio rerio (Dre) dre10831 ENSDARP00000041800
Encephalitozoon cuniculi (Ecu) ecu1381 19173230
Gallus gallus (Gga) gga22612 ENSGALP00000014651
(PIGK)
Q5F451
Homo sapiens (Hsa) hsa1376 ENSP00000271047
Homo sapiens (Hsa) hsa1377 ENSP00000352041
(PIGK)
A6NEM5
Kluyveromyces lactis (Kla) kla3717 KLLA0E17105g
Mus musculus (Mmu) mmu17724 ENSMUSP00000045351
(MGI:1913863)
Q8BL63
Mus musculus (Mmu) mmu17723 ENSMUSP00000057498
(MGI:1913863)
Q9CXY9
Neurospora crassa (Ncr) ncr7065 NCU07259.2
Oryza sativa (Osa) osa30091 4297.m00136
Oryza sativa (Osa) osa29421 4325.m00159
Oryza sativa (Osa) osa36463 4934.m00108
Plasmodium falciparum (Pfa) pfa749 PF11_0298
Rattus norvegicus (Rno) rno17192 ENSRNOP00000014725
(RGD:1306753)
Q5XIP2
Rattus norvegicus (Rno) rno17191 ENSRNOP00000032696
Saccharomyces cerevisiae (Sce) sce1389 YDR331W
(S000002739)
Schizosaccharomyces pombe (Spo) spo4826 SPCC11E10.02c Q9USP5
Yarrowia lipolytica (Yli) yli5668 YALI0F07733g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1913863
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC11E10.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002739
GO:0042765 GPI-anchor transamidase complex C
IGI
SpoSPCC11E10.02c
IPI
SceS000002739
GO:0003674 molecular_function F
ND
MmuMGI:1913863
GO:0003923 GPI-anchor transamidase activity F
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
IPI
SceS000002739
ISS
AthAt1g08750
DmeFBgn0023545
GO:0004197 cysteine-type endopeptidase activity F
ISS
SpoSPCC11E10.02c
GO:0000003 reproduction P
IMP
CelWBGene00011482
GO:0006508 proteolysis P
ISS
AthAt1g08750
GO:0008150 biological_process P
ND
MmuMGI:1913863
GO:0016255 attachment of GPI anchor to protein P
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
GO:0042157 lipoprotein metabolic process P
RCA
SceS000002739

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC11E10.02c
(Q9USP5)
YDR331W
(S000002739)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPCC11E10.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002739
GO:0042765 GPI-anchor transamidase complex C
IGI
SpoSPCC11E10.02c
IPI
SceS000002739
GO:0003923 GPI-anchor transamidase activity F
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
IPI
SceS000002739
GO:0004197 cysteine-type endopeptidase activity F
ISS
SpoSPCC11E10.02c
GO:0016255 attachment of GPI anchor to protein P
IGI
SpoSPCC11E10.02c
IMP
SceS000002739
GO:0042157 lipoprotein metabolic process P
RCA
SceS000002739

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk