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Search term: YDR335W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSN5
SGD link S000002743
Alternative ID YDR335W
Description Karyopherin involved in nuclear import and export of proteins, including import of replication protein A and export of Swi6p, Far1p, and Pho4p; required for re-export of mature tRNAs after their retrograde import from the cytoplasm
Synonyms YDR335W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2020 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Nuclear transport receptor CRM1/MSN5 (importin beta superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g03110 GI:6714425
Arabidopsis thaliana (Ath) At3g05040 GI:15229879
Arabidopsis thaliana (Ath) At5g17020 GI:15237894
Caenorhabditis elegans (Cel) CE23467
(WBGene00002078)		 GI:17566910
Drosophila melanogaster (Dme) 7290037 GI:17864544
Drosophila melanogaster (Dme) 7293623 GI:7293623
Homo sapiens (Hsa) Hs18583463 GI:18583463
Homo sapiens (Hsa) Hs20562336 GI:20562336
Homo sapiens (Hsa) Hs22060276 GI:20555117
Homo sapiens (Hsa) Hs4507943
(XPO1)		 GI:4507943 O14980
Saccharomyces cerevisiae (Sce) YDR335w
(S000002743)		 GI:6320542 P52918
Saccharomyces cerevisiae (Sce) YGR218w
(S000003450)		 GI:6321657 P30822
Schizosaccharomyces pombe (Spo) SPAC1805.17 GI:19114840 P14068
Schizosaccharomyces pombe (Spo) SPAC328.01c GI:19115115 O14116
Schizosaccharomyces pombe (Spo) SPAC3A11.01c GI:19115114
Encephalitozoon cuniculi (Ecu) ECU11g0240 GI:19074824 Q8SU86


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
HsaXPO1
SceS000003450
GO:0005634 nucleus C
IDA
SceS000002743
S000003450
SpoSPAC1805.17
SPAC328.01c
ISS
AthAt3g03110
At5g17020
SpoSPAC328.01c
TAS
AthAt5g17020
GO:0005635 nuclear envelope C
IDA
SpoSPAC328.01c
SPAC1805.17
NAS
AthAt3g05040
RCA
SceS000002743
TAS
HsaXPO1
GO:0005642 annulate lamellae C
IDA
HsaXPO1
GO:0005643 nuclear pore C
ISS
AthAt5g17020
At3g03110
SpoSPAC1805.17
NAS
SpoSPAC328.01c
RCA
SceS000002743
GO:0005654 nucleoplasm C
EXP
HsaXPO1
GO:0005737 cytoplasm C
ISS
AthAt5g17020
At3g03110
GO:0005816 spindle pole body C
IDA
SceS000003450
GO:0005829 cytosol C
EXP
HsaXPO1
IDA
SpoSPAC1805.17
SPAC328.01c
GO:0016021 integral to membrane C
RCA
SceS000002743
GO:0030529 ribonucleoprotein complex C
IDA
HsaXPO1
GO:0031224 intrinsic to membrane C
RCA
SceS000002743
GO:0046930 pore complex C
RCA
SceS000002743
GO:0004872 receptor activity F
ISS
AthAt5g17020
GO:0005487 nucleocytoplasmic transporter activity F
NAS
AthAt3g05040
GO:0005515 protein binding F
IPI
AthAt5g17020
HsaXPO1
SceS000002743
GO:0005525 GTP binding F
NAS
SpoSPAC1805.17
SPAC328.01c
GO:0008262 importin-alpha export receptor
activity		 F
IDA
SceS000002743
ISS
SceS000002743
GO:0008565 protein transporter activity F
IDA
SceS000003450
IMP
SceS000003450
ISS
AthAt3g03110
At5g17020
SpoSPAC1805.17
NAS
SpoSPAC328.01c
GO:0000055 ribosomal large subunit export from
nucleus		 P
IMP
SceS000003450
ISS
SpoSPAC1805.17
GO:0000059 protein import into nucleus, docking P
ISS
AthAt5g17020
At3g03110
GO:0002119 nematode larval development P
IMP
CelWBGene00002078
GO:0006403 RNA localization P
RCA
SceS000002743
GO:0006406 mRNA export from nucleus P
IMP
SceS000003450
GO:0006407 rRNA export from nucleus P
RCA
SceS000002743
GO:0006408 snRNA export from nucleus P
RCA
SceS000002743
GO:0006409 tRNA export from nucleus P
RCA
SceS000002743
GO:0006606 protein import into nucleus P
RCA
SceS000003450
S000002743
GO:0006607 NLS-bearing substrate import into
nucleus		 P
RCA
SceS000002743
GO:0006608 snRNP protein import into nucleus P
RCA
SceS000002743
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
RCA
SceS000002743
GO:0006610 ribosomal protein import into nucleus P
RCA
SceS000002743
GO:0006611 protein export from nucleus P
IDA
SceS000002743
IGI
SpoSPAC1805.17
IMP
SceS000003450
ISS
AthAt5g17020
SpoSPAC328.01c
GO:0006999 nuclear pore organization P
RCA
SceS000002743
GO:0009415 response to water P
RCA
SceS000002743
GO:0009553 embryo sac development P
IGI
AthAt5g17020
At3g03110
GO:0009555 pollen development P
IGI
AthAt5g17020
At3g03110
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002078
GO:0009846 pollen germination P
IGI
AthAt5g17020
At3g03110
GO:0009860 pollen tube growth P
IGI
AthAt5g17020
At3g03110
GO:0009910 negative regulation of flower development P
IMP
AthAt3g05040
GO:0009944 polarity specification of adaxial/abaxial
axis		 P
IMP
AthAt3g05040
GO:0009965 leaf morphogenesis P
IMP
AthAt3g05040
GO:0010171 body morphogenesis P
IMP
CelWBGene00002078
GO:0015931 nucleobase, nucleoside, nucleotide and nucleic
acid transport		 P
RCA
SceS000002743
GO:0017038 protein import P
RCA
SceS000002743
GO:0033365 protein localization in organelle P
RCA
SceS000002743
GO:0034501 protein localization to kinetochore P
IGI
SceS000003450
GO:0034504 protein localization in nucleus P
RCA
SceS000003450
S000002743
GO:0034599 cellular response to oxidative
stress		 P
IMP
SpoSPAC1805.17
GO:0035281 pre-microRNA export from nucleus P
TAS
AthAt3g05040
GO:0040007 growth P
IMP
CelWBGene00002078
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002078
GO:0040011 locomotion P
IMP
CelWBGene00002078
GO:0045184 establishment of protein localization P
RCA
SceS000002743
GO:0048364 root development P
IMP
AthAt3g05040
GO:0048367 shoot development P
IMP
AthAt3g05040
GO:0051029 rRNA transport P
RCA
SceS000002743
GO:0051030 snRNA transport P
RCA
SceS000002743
GO:0051031 tRNA transport P
RCA
SceS000002743
GO:0051168 nuclear export P
IMP
SpoSPAC1805.17
GO:0051170 nuclear import P
RCA
SceS000003450
S000002743
GO:0051301 cell division P
IMP
CelWBGene00002078
GO:0071313 cellular response to caffeine P
IMP
SpoSPAC1805.17
GO:0071528 tRNA re-export from nucleus P
IGI
SceS000002743

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38780

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC328.01c GI:63054601 O14116
Saccharomyces cerevisiae (Sce) MSN5
(S000002743)		 GI:6320542 P52918
Kluyveromyces lactis (Kla) KLLA0F21648g GI:50312029
Eremothecium gossypii (Ego) AGOS_AEL094C GI:45190513
Magnaporthe grisea (Mgr) MGG_09560 GI:145602668
Neurospora crassa (Ncr) NCU02387.1 GI:32421439