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Search term: YDR349C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YPS7
SGD link S000002757
Alternative ID YDR349C
Description Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum
Synonyms YDR349C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1339 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Aspartyl protease

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g01300 GI:15223368
Arabidopsis thaliana (Ath) At1g03220 GI:15218740
Arabidopsis thaliana (Ath) At1g03230 GI:18379072
Arabidopsis thaliana (Ath) At1g05840 GI:18390579
Arabidopsis thaliana (Ath) At1g08210 GI:6579210
Arabidopsis thaliana (Ath) At1g09750 GI:15218254
Arabidopsis thaliana (Ath) At1g11910 GI:15221141
Arabidopsis thaliana (Ath) At1g25510 GI:15222611
Arabidopsis thaliana (Ath) At1g31450 GI:15222357
Arabidopsis thaliana (Ath) At1g44130 GI:15219354
Arabidopsis thaliana (Ath) At1g49050 GI:15222029
Arabidopsis thaliana (Ath) At1g62290 GI:15220747
Arabidopsis thaliana (Ath) At1g64830 GI:15217764
Arabidopsis thaliana (Ath) At1g65240 GI:15217887
Arabidopsis thaliana (Ath) At1g66180 GI:18408451
Arabidopsis thaliana (Ath) At1g69100 GI:15222219
Arabidopsis thaliana (Ath) At1g77480 GI:15223969
Arabidopsis thaliana (Ath) At1g79720 GI:7715602
Arabidopsis thaliana (Ath) At2g03200 GI:7487145
Arabidopsis thaliana (Ath) At2g17760 GI:15227889
Arabidopsis thaliana (Ath) At2g28010 GI:15226315
Arabidopsis thaliana (Ath) At2g28030 GI:15226317
Arabidopsis thaliana (Ath) At2g28040 GI:15226319
Arabidopsis thaliana (Ath) At2g28220 GI:15226358
Arabidopsis thaliana (Ath) At2g36670 GI:15228017
Arabidopsis thaliana (Ath) At2g39710 GI:7487691
Arabidopsis thaliana (Ath) At2g42980 GI:15228044
Arabidopsis thaliana (Ath) At3g02740 GI:15232960
Arabidopsis thaliana (Ath) At3g12700 GI:15230568
Arabidopsis thaliana (Ath) At3g18490 GI:15229656
Arabidopsis thaliana (Ath) At3g20015 GI:15231010
Arabidopsis thaliana (Ath) At3g25700 GI:15230868
Arabidopsis thaliana (Ath) At3g42550 GI:15228576
Arabidopsis thaliana (Ath) At3g50050 GI:15229663
Arabidopsis thaliana (Ath) At3g51330 GI:11281623
Arabidopsis thaliana (Ath) At3g51340 GI:15230458
Arabidopsis thaliana (Ath) At3g51350 GI:15230460
Arabidopsis thaliana (Ath) At3g51360 GI:15230462
Arabidopsis thaliana (Ath) At3g52500 GI:18409620
Arabidopsis thaliana (Ath) At3g54400 GI:15232503
Arabidopsis thaliana (Ath) At3g59080 GI:15231625
Arabidopsis thaliana (Ath) At3g61820 GI:15228618
Arabidopsis thaliana (Ath) At4g04460 GI:15233518
Arabidopsis thaliana (Ath) At4g12920 GI:15235526
Arabidopsis thaliana (Ath) At4g16560_1 GI:7485159
Arabidopsis thaliana (Ath) At4g22050 GI:15234696
Arabidopsis thaliana (Ath) At4g30030 GI:15234606
Arabidopsis thaliana (Ath) At4g30040 GI:15234607
Arabidopsis thaliana (Ath) At4g33490 GI:7484812
Arabidopsis thaliana (Ath) At4g35880 GI:15233372
Arabidopsis thaliana (Ath) At5g02190 GI:15241713
Arabidopsis thaliana (Ath) At5g07030 GI:15240680
Arabidopsis thaliana (Ath) At5g10080 GI:15238055
Arabidopsis thaliana (Ath) At5g10760 GI:15238250
Arabidopsis thaliana (Ath) At5g10770 GI:15238251
Arabidopsis thaliana (Ath) At5g19100 GI:15239644
Arabidopsis thaliana (Ath) At5g19110 GI:15239655
Arabidopsis thaliana (Ath) At5g19120 GI:15239656
Arabidopsis thaliana (Ath) At5g22850 GI:15237145
Arabidopsis thaliana (Ath) At5g24820 GI:18420846
Arabidopsis thaliana (Ath) At5g33340 GI:15242803
Arabidopsis thaliana (Ath) At5g33350 GI:15242805
Arabidopsis thaliana (Ath) At5g36260 GI:15239353
Arabidopsis thaliana (Ath) At5g37540 GI:15240269
Arabidopsis thaliana (Ath) At5g43100 GI:15239176
Arabidopsis thaliana (Ath) At5g45120 GI:15242307
Arabidopsis thaliana (Ath) At5g48430 GI:15238970
Caenorhabditis elegans (Cel) CE03567
(WBGene00000217)		 GI:17549909 Q21966
Caenorhabditis elegans (Cel) CE03881_2 GI:17549964
Caenorhabditis elegans (Cel) CE04749
(WBGene00019619)		 GI:17568861 Q94271
Caenorhabditis elegans (Cel) CE04971 GI:17557204
Caenorhabditis elegans (Cel) CE05287
(WBGene00007605)		 GI:17557992 Q18020
Caenorhabditis elegans (Cel) CE09538 GI:17560022
Caenorhabditis elegans (Cel) CE09539
(WBGene00000218)		 GI:17557206 O01532
Caenorhabditis elegans (Cel) CE09540
(WBGene00017678)		 GI:17560024 O01531
Caenorhabditis elegans (Cel) CE09541 GI:17560028
Caenorhabditis elegans (Cel) CE09542
(WBGene00000219)		 GI:17557208 O01530
Caenorhabditis elegans (Cel) CE09738
(WBGene00017881)		 GI:17560290 Q22972
Caenorhabditis elegans (Cel) CE11478 GI:17561738
Caenorhabditis elegans (Cel) CE11480
(WBGene00019105)		 GI:17561740 O16338
Caenorhabditis elegans (Cel) CE16843
(WBGene00015700)		 GI:17538662 O45072
Caenorhabditis elegans (Cel) CE19495
(WBGene00000216)		 GI:17549907 P55956
Caenorhabditis elegans (Cel) CE20430 GI:17566864
Caenorhabditis elegans (Cel) CE21681 GI:17565564
Caenorhabditis elegans (Cel) CE21683 GI:17565562
Caenorhabditis elegans (Cel) CE21684 GI:17565560
Caenorhabditis elegans (Cel) CE21685 GI:17565558
Drosophila melanogaster (Dme) 7290034
(FBgn0003044)		 GI:17986011
Drosophila melanogaster (Dme) 7296074 GI:7296074 Q9VQ14
Drosophila melanogaster (Dme) 7296075 GI:7296075 Q9VQ13
Drosophila melanogaster (Dme) 7296076 GI:19920514
Drosophila melanogaster (Dme) 7296077 GI:7296077
Drosophila melanogaster (Dme) 7297427
(FBgn0032049)		 GI:20129385
Drosophila melanogaster (Dme) 7297765 GI:7297765 Q9VKP7
Drosophila melanogaster (Dme) 7297766
(FBgn0032304)		 GI:19921120
Drosophila melanogaster (Dme) 7300253 GI:7300253 Q9VEK5
Drosophila melanogaster (Dme) 7300254 GI:7300254
Drosophila melanogaster (Dme) 7300255 GI:7300255 Q9VEK3
Drosophila melanogaster (Dme) 7303185 GI:7303185 A1Z9Q9
Drosophila melanogaster (Dme) 7304149 GI:6685167
Homo sapiens (Hsa) Hs18549644 GI:18549644
Homo sapiens (Hsa) Hs19923395
(BACE2)		 GI:19923395 Q9Y5Z0
Homo sapiens (Hsa) Hs21040360 GI:21040360 Q9Y5Z0
Homo sapiens (Hsa) Hs21040362 GI:21040362 Q9Y5Z0
Homo sapiens (Hsa) Hs21040364 GI:21040364 P56817
Homo sapiens (Hsa) Hs21040366 GI:21040366 P56817
Homo sapiens (Hsa) Hs21040368 GI:21040368 P56817
Homo sapiens (Hsa) Hs22040925 GI:22040925
Homo sapiens (Hsa) Hs22050827 GI:22050827
Homo sapiens (Hsa) Hs22063872 GI:22063872
Homo sapiens (Hsa) Hs22063875 GI:22063875
Homo sapiens (Hsa) Hs22063919 GI:22063919
Homo sapiens (Hsa) Hs4503143
(CTSD)		 GI:4503143 P07339
Homo sapiens (Hsa) Hs4503145
(CTSE)		 GI:4503145 P14091
Homo sapiens (Hsa) Hs4505757
(PGC)		 GI:4505757 P20142
Homo sapiens (Hsa) Hs4506475
(REN)		 GI:4506475 Q15296
Homo sapiens (Hsa) Hs4758754
(NAPSA)		 GI:4758754 O96009
Homo sapiens (Hsa) Hs6912266
(BACE1)		 GI:6912266 P56817
Saccharomyces cerevisiae (Sce) YDR144c
(S000002551)		 GI:6320348 P53379
Saccharomyces cerevisiae (Sce) YDR349c
(S000002757)		 GI:6320556 Q06325
Saccharomyces cerevisiae (Sce) YGL258w-a GI:13129168 Q3E740
Saccharomyces cerevisiae (Sce) YGL259w
(S000003228)		 GI:6321178 P53057
Saccharomyces cerevisiae (Sce) YIL015w
(S000001277)		 GI:6322174 P12630
Saccharomyces cerevisiae (Sce) YIR039c
(S000001478)		 GI:6322230 P40583
Saccharomyces cerevisiae (Sce) YLR120c
(S000004110)		 GI:6323149 P32329
Saccharomyces cerevisiae (Sce) YLR121c
(S000004111)		 GI:6323150 Q12303
Saccharomyces cerevisiae (Sce) YPL154c
(S000006075)		 GI:6325103 P07267
Schizosaccharomyces pombe (Spo) SPAC26A3.01 GI:19115056 P32834
Schizosaccharomyces pombe (Spo) SPCC1795.09 GI:19075535 O59774


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
TAS
SceS000006075
GO:0000328 fungal-type vacuole lumen C
TAS
SceS000006075
GO:0005575 cellular_component C
ND
AthAt3g12700
At4g16560
SceS000003228
YGL258w-a
GO:0005576 extracellular region C
NAS
HsaCTSD
GO:0005615 extracellular space C
IDA
HsaCTSD
REN
TAS
HsaPGC
GO:0005618 cell wall C
IDA
AthAt1g03230
At1g03220
At1g09750
At3g52500
At3g54400
At5g07030
TAS
SpoSPCC1795.09
GO:0005634 nucleus C
IDA
DmeFBgn0003044
ISS
DmeFBgn0003044
NAS
DmeFBgn0003044
GO:0005737 cytoplasm C
IDA
SceS000002757
GO:0005739 mitochondrion C
IDA
SceS000006075
GO:0005764 lysosome C
IC
CelWBGene00000217
NAS
HsaCTSD
GO:0005768 endosome C
IDA
HsaCTSE
GO:0005773 vacuole C
IDA
AthAt1g62290
At1g11910
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g02190
SceS000002757
SpoSPAC26A3.01
SPCC1795.09
GO:0005794 Golgi apparatus C
IDA
HsaBACE2
GO:0005886 plasma membrane C
IDA
AthAt3g02740
At1g03220
At1g65240
SceS000004111
SpoSPAC26A3.01
ISS
SceS000004111
GO:0009277 fungal-type cell wall C
IDA
SceS000002551
S000001478
S000004110
GO:0009505 plant-type cell wall C
IDA
AthAt1g08210
At1g01300
At1g44130
At1g03220
At1g03230
At1g09750
At3g61820
At3g52500
At3g54400
At5g07030
GO:0009507 chloroplast C
IDA
AthAt3g54400
GO:0009986 cell surface C
NAS
SpoSPCC1795.09
TAS
SpoSPAC26A3.01
GO:0016020 membrane C
IDA
AthAt3g52500
At1g01300
At1g03220
GO:0016021 integral to membrane C
NAS
HsaBACE2
GO:0030287 cell wall-bounded periplasmic space C
TAS
SceS000001277
GO:0031012 extracellular matrix C
IDA
HsaCTSD
GO:0031225 anchored to membrane C
TAS
AthAt5g36260
At2g17760
At3g02740
At1g05840
At1g08210
At1g65240
At3g51330
At3g51350
At4g35880
At5g10080
GO:0046658 anchored to plasma membrane C
IDA
AthAt1g65240
At5g10080
SceS000004111
IPI
SceS000004111
GO:0048046 apoplast C
IDA
AthAt5g33340
At1g79720
At1g09750
At3g54400
At5g10760
GO:0003674 molecular_function F
ND
SceYGL258w-a
GO:0003677 DNA binding F
IDA
DmeFBgn0003044
ISS
AthAt3g59080
At5g10770
GO:0003700 transcription factor activity F
IDA
DmeFBgn0003044
GO:0004175 endopeptidase activity F
IDA
AthAt1g11910
RCA
SceS000006075
GO:0004190 aspartic-type endopeptidase activity F
IDA
AthAt5g33340
HsaBACE2
CTSE
REN
SceS000002551
S000004110
S000001277
S000004111
IMP
SceS000001277
ISS
AthAt5g33340
At5g02190
CelWBGene00000217
DmeFBgn0032304
FBgn0032049
SceS000002757
S000003228
S000001478
S000004111
RCA
SceS000006075
TAS
SpoSPAC26A3.01
GO:0005102 receptor binding F
IPI
HsaREN
GO:0005199 structural constituent of cell
wall		 F
IPI
SceS000004111
GO:0005515 protein binding F
IPI
DmeFBgn0003044
GO:0008233 peptidase activity F
IDA
AthAt5g02190
HsaREN
SceS000006075
GO:0070001 aspartic-type peptidase activity F
RCA
SceS000006075
GO:0070011 peptidase activity, acting on L-amino acid
peptides		 F
RCA
SceS000006075
GO:0000746 conjugation P
RCA
SceS000001277
GO:0000747 conjugation with cellular fusion P
IMP
SpoSPAC26A3.01
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IDA
SceS000001277
IMP
SceS000001277
GO:0001822 kidney development P
IMP
HsaREN
GO:0002003 angiotensin maturation P
IDA
HsaREN
GO:0006414 translational elongation P
RCA
SceS000004111
GO:0006508 proteolysis P
IDA
AthAt1g11910
HsaREN
IMP
CelWBGene00000217
SceS000002551
ISS
AthAt2g03200
At5g45120
At1g64830
At2g42980
At3g18490
At3g42550
At2g28030
At1g08210
At1g31450
At2g28220
At5g33340
At2g28040
At1g66180
At1g79720
At1g05840
At2g28010
At1g25510
At3g02740
At1g01300
At2g36670
At2g39710
At1g69100
At2g17760
At1g62290
At1g65240
At1g49050
At1g11910
At3g12700
At3g51360
At3g20015
At5g22850
At3g50050
At3g51350
At3g52500
At3g51330
At3g51340
At4g04460
At5g37540
At3g54400
At5g36260
At5g24820
At5g43100
At4g12920
At3g61820
At4g30040
At4g22050
At4g30030
At4g35880
At5g10760
At5g07030
At5g10080
NAS
HsaBACE2
GO:0006509 membrane protein ectodomain proteolysis P
IDA
HsaBACE2
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000006075
RCA
SceS000006075
GO:0007586 digestion P
TAS
HsaCTSE
GO:0008150 biological_process P
ND
SceS000003228
YGL258w-a
GO:0008217 regulation of blood pressure P
TAS
HsaREN
GO:0008219 cell death P
IMP
CelWBGene00000217
WBGene00000218
WBGene00000219
WBGene00000216
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000216
GO:0009267 cellular response to starvation P
IMP
SceS000006075
GO:0009651 response to salt stress P
IEP
AthAt1g03220
At1g03230
At1g11910
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g02190
GO:0010310 regulation of hydrogen peroxide metabolic
process		 P
IDA
AthAt5g33340
IMP
AthAt5g33340
GO:0010337 regulation of salicylic acid metabolic
process		 P
IMP
AthAt5g33340
GO:0012501 programmed cell death P
IMP
AthAt5g02190
GO:0012502 induction of programmed cell death P
IMP
CelWBGene00000217
GO:0016237 microautophagy P
IMP
SceS000006075
GO:0016485 protein processing P
IDA
SceS000004110
RCA
SceS000002551
GO:0016486 peptide hormone processing P
NAS
HsaBACE2
GO:0016568 chromatin modification P
IDA
DmeFBgn0003044
GO:0019236 response to pheromone P
RCA
SceS000001277
GO:0019886 antigen processing and presentation of exogenous
peptide antigen via MHC class II		 P
IDA
HsaCTSE
GO:0019953 sexual reproduction P
RCA
SceS000001277
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
IMP
SceS000006075
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002551
S000002757
S000001478
S000004110
S000004111
GO:0040011 locomotion P
IMP
CelWBGene00000218
GO:0042742 defense response to bacterium P
IMP
AthAt5g33340
GO:0042985 negative regulation of amyloid precursor protein
biosynthetic process		 P
IMP
HsaBACE2
GO:0043171 peptide catabolic process P
IDA
SceS000001277
GO:0043408 regulation of MAPKKK cascade P
IDA
HsaREN
GO:0044267 cellular protein metabolic process P
IDA
SceS000004111
ISS
SceS000004111
GO:0045892 negative regulation of transcription,
DNA-dependent		 P
IDA
DmeFBgn0003044
GO:0046686 response to cadmium ion P
IEP
AthAt4g04460
GO:0051603 proteolysis involved in cellular protein catabolic
process		 P
IMP
SceS000006075
GO:0051604 protein maturation P
RCA
SceS000002551

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38786

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YPS7
(S000002757)		 GI:6320556 Q06325
Kluyveromyces lactis (Kla) KLLA0F22088g GI:50312069
Eremothecium gossypii (Ego) AGOS_ACR150W GI:45185836


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002757
GO:0005783 endoplasmic reticulum C
IDA
SceS000002757
GO:0004190 aspartic-type endopeptidase activity F
ISS
SceS000002757
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002757

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_17704

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1197 ACR150W
Candida glabrata (Cgl) cgl97 CAGL0A02431g
Debaryomyces hansenii (Dha) dha4052 DEHA0E18326g
Kluyveromyces lactis (Kla) kla5066 KLLA0F22088g
Saccharomyces cerevisiae (Sce) sce1407 YDR349C
(S000002757)
Yarrowia lipolytica (Yli) yli4898 YALI0E24981g
Yarrowia lipolytica (Yli) yli5298 YALI0E34331g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002757
GO:0005783 endoplasmic reticulum C
IDA
SceS000002757
GO:0004190 aspartic-type endopeptidase activity F
ISS
SceS000002757
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002757

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1795.09
(O59774)		 YDR349C
(S000002757)
SPAC26A3.01
(P32834)		 YDR349C
(S000002757)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
TAS
SpoSPCC1795.09
GO:0005737 cytoplasm C
IDA
SceS000002757
GO:0005783 endoplasmic reticulum C
IDA
SceS000002757
SpoSPAC26A3.01
SPCC1795.09
GO:0005886 plasma membrane C
IDA
SpoSPAC26A3.01
GO:0009986 cell surface C
NAS
SpoSPCC1795.09
TAS
SpoSPAC26A3.01
GO:0004190 aspartic-type endopeptidase activity F
ISS
SceS000002757
TAS
SpoSPAC26A3.01
GO:0000747 conjugation with cellular fusion P
IMP
SpoSPAC26A3.01
GO:0031505 fungal-type cell wall organization P
IGI
SceS000002757

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