YOGY Home YOGY Help

Search term: YDR372C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VPS74
SGD link S000002780
Alternative ID YDR372C
Description Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function
Synonyms YDR372C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3983 -CDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Golgi protein

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE24362
(WBGene00021644)		 GI:17510021 Q9N3S8
Drosophila melanogaster (Dme) 7295987 GI:19920564 Q9VQ93
Homo sapiens (Hsa) Hs11545859
(GOLPH3)		 GI:11545859 Q9H4A6
Homo sapiens (Hsa) Hs21361716 GI:10803417 Q9H4A5
Homo sapiens (Hsa) HsM8922589 GI:8922589
Saccharomyces cerevisiae (Sce) YDR372c
(S000002780)		 GI:6320580 Q06385
Schizosaccharomyces pombe (Spo) SPAC5D6.13 GI:19114269 O14205
Encephalitozoon cuniculi (Ecu) ECU07g0370 GI:19074459 Q8SV34


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002780
SpoSPAC5D6.13
GO:0005737 cytoplasm C
IDA
SceS000002780
GO:0005739 mitochondrion C
IDA
HsaGOLPH3
GO:0005794 Golgi apparatus C
IDA
SceS000002780
ISS
SpoSPAC5D6.13
GO:0005802 trans-Golgi network C
IDA
HsaGOLPH3
GO:0005829 cytosol C
IDA
HsaGOLPH3
SceS000002780
SpoSPAC5D6.13
GO:0019898 extrinsic to membrane C
IDA
SceS000002780
GO:0003674 molecular_function F
ND
SpoSPAC5D6.13
GO:0005515 protein binding F
IGI
SceS000002780
IPI
HsaGOLPH3
SceS000002780
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000002780
IMP
SceS000002780
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0008283 cell proliferation P
IMP
HsaGOLPH3
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00021644
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021644
GO:0010171 body morphogenesis P
IMP
CelWBGene00021644
GO:0010821 regulation of mitochondrion organization P
IDA
HsaGOLPH3
GO:0030968 endoplasmic reticulum unfolded protein
response		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0032008 positive regulation of TOR signaling
cascade		 P
IMP
HsaGOLPH3
GO:0034067 protein localization in Golgi apparatus P
IMP
SceS000002780
GO:0040011 locomotion P
IMP
CelWBGene00021644

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56942

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GOLPH3 GI:11545859 Q9H4A6
Pan troglodytes (Ptr) GOLPH3 GI:55624518
Canis familiaris (Cfa) GOLPH3 GI:73954363
Mus musculus (Mmu) Golph3
(MGI:1913879)		 GI:14140240 Q05BZ0
Rattus norvegicus (Rno) Golph3
(RGD:621226)		 GI:62461580
Gallus gallus (Gga) GOLPH3 GI:118103660
Drosophila melanogaster (Dme) l(2)s5379
(FBgn0010704)		 GI:78706834
Anopheles gambiae (Aga) AgaP_AGAP012632 GI:31197197
Anopheles gambiae (Aga) AgaP_AGAP012606 GI:31194093
Caenorhabditis elegans (Cel) Y47G6A.18
(CE24362;
WBGene00021644)		 GI:17510021 Q9N3S8
Schizosaccharomyces pombe (Spo) SPAPJ735.02c GI:67995539
Saccharomyces cerevisiae (Sce) VPS74
(S000002780)		 GI:6320580 Q06385
Kluyveromyces lactis (Kla) KLLA0E02354g GI:50308107
Eremothecium gossypii (Ego) AGOS_ACL165C GI:45185523
Magnaporthe grisea (Mgr) MGG_00839 GI:39974029
Neurospora crassa (Ncr) NCU06091.1 GI:32410931


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002780
GO:0005737 cytoplasm C
IDA
SceS000002780
GO:0005739 mitochondrion C
IDA
HsaGOLPH3
GO:0005768 endosome C
ISO
MmuMGI:1913879
GO:0005794 Golgi apparatus C
IDA
MmuMGI:1913879
SceS000002780
GO:0005802 trans-Golgi network C
IDA
HsaGOLPH3
ISO
MmuMGI:1913879
GO:0005829 cytosol C
IDA
HsaGOLPH3
SceS000002780
ISO
MmuMGI:1913879
GO:0005886 plasma membrane C
ISO
MmuMGI:1913879
GO:0019898 extrinsic to membrane C
IDA
SceS000002780
GO:0005515 protein binding F
IGI
SceS000002780
IPI
HsaGOLPH3
SceS000002780
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000002780
IMP
SceS000002780
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000002780
GO:0008283 cell proliferation P
IMP
HsaGOLPH3
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00021644
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021644
GO:0010171 body morphogenesis P
IMP
CelWBGene00021644
GO:0010821 regulation of mitochondrion organization P
IDA
HsaGOLPH3
GO:0030968 endoplasmic reticulum unfolded protein
response		 P
IMP
SceS000002780
GO:0032008 positive regulation of TOR signaling
cascade		 P
IMP
HsaGOLPH3
GO:0034067 protein localization in Golgi apparatus P
IMP
SceS000002780
GO:0040011 locomotion P
IMP
CelWBGene00021644

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4031

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14163 ENSANGP00000012745
Anopheles gambiae (Aga) aga12645 ENSANGP00000015241
Ashbya gossypii (Ago) ago884 ACL165C
Caenorhabditis elegans (Cel) cel19125 Y47G6A.18
(CE24362;
WBGene00021644)
Candida glabrata (Cgl) cgl120 CAGL0A02926g
Cryptococcus neoformans (Cne) cne3980 185.m02579
Dictyostelium discoideum (Ddi) ddi9542 DDB0219659
Debaryomyces hansenii (Dha) dha6130 DEHA0G09658g
Drosophila melanogaster (Dme) dme350 CG7085-PA
(FBgn0010704)
Danio rerio (Dre) dre19889 ENSDARP00000027667
Takifugu rubripes (Fru) fru12858 SINFRUP00000143696
Gallus gallus (Gga) gga28280 ENSGALP00000004980
(GOLPH3)
Gallus gallus (Gga) gga23875 ENSGALP00000023549
(GOLPH3L)
Homo sapiens (Hsa) hsa25088 ENSP00000265070
(GOLPH3)		 Q9H4A6
Homo sapiens (Hsa) hsa1960 ENSP00000271732
(GOLPH3L)		 Q9H4A5
Kluyveromyces lactis (Kla) kla3053 KLLA0E02354g
Mus musculus (Mmu) mmu8792 ENSMUSP00000057375
(MGI:1913879)		 Q9CRA5-1
Mus musculus (Mmu) mmu17150 ENSMUSP00000058654
(MGI:1917129)		 Q8R088-1
Neurospora crassa (Ncr) ncr5920 NCU06091.2
Rattus norvegicus (Rno) rno15666 ENSRNOP00000017276
(RGD:621226)		 Q569C9
Saccharomyces cerevisiae (Sce) sce1435 YDR372C
(S000002780)
Schizosaccharomyces pombe (Spo) spo937 SPAC5D6.13 O14205
Yarrowia lipolytica (Yli) yli2853 YALI0D03575g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002780
SpoSPAC5D6.13
GO:0005737 cytoplasm C
IDA
SceS000002780
GO:0005768 endosome C
ISO
MmuMGI:1913879
GO:0005794 Golgi apparatus C
IDA
MmuMGI:1913879
SceS000002780
ISO
MmuMGI:1917129
ISS
SpoSPAC5D6.13
GO:0005802 trans-Golgi network C
ISO
MmuMGI:1913879
GO:0005829 cytosol C
IDA
SceS000002780
SpoSPAC5D6.13
ISO
MmuMGI:1913879
GO:0005886 plasma membrane C
ISO
MmuMGI:1913879
GO:0019898 extrinsic to membrane C
IDA
SceS000002780
GO:0003674 molecular_function F
ND
MmuMGI:1917129
SpoSPAC5D6.13
GO:0005515 protein binding F
IGI
SceS000002780
IPI
SceS000002780
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000002780
IMP
SceS000002780
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0008150 biological_process P
ND
MmuMGI:1917129
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00021644
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00021644
GO:0010171 body morphogenesis P
IMP
CelWBGene00021644
GO:0030968 endoplasmic reticulum unfolded protein
response		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0034067 protein localization in Golgi apparatus P
IMP
SceS000002780
GO:0040011 locomotion P
IMP
CelWBGene00021644

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC5D6.13
(O14205)		 YDR372C
(S000002780)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002780
SpoSPAC5D6.13
GO:0005737 cytoplasm C
IDA
SceS000002780
GO:0005794 Golgi apparatus C
IDA
SceS000002780
ISS
SpoSPAC5D6.13
GO:0005829 cytosol C
IDA
SceS000002780
SpoSPAC5D6.13
GO:0019898 extrinsic to membrane C
IDA
SceS000002780
GO:0003674 molecular_function F
ND
SpoSPAC5D6.13
GO:0005515 protein binding F
IGI
SceS000002780
IPI
SceS000002780
GO:0070273 phosphatidylinositol-4-phosphate
binding		 F
IDA
SceS000002780
IMP
SceS000002780
GO:0006890 retrograde vesicle-mediated transport, Golgi to
ER		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0030968 endoplasmic reticulum unfolded protein
response		 P
IMP
SceS000002780
ISS
SpoSPAC5D6.13
GO:0034067 protein localization in Golgi apparatus P
IMP
SceS000002780

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk