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Search term: YDR380W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ARO10
SGD link S000002788
Alternative ID YDR380W
Description Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway
Synonyms YDR380W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1184 A---YP-

KOGs classification KOGs description
METABOLISMMETABOLISM Thiamine pyrophosphate-requiring enzyme

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g33070 GI:15234062
Arabidopsis thaliana (Ath) At5g01320 GI:15240950
Arabidopsis thaliana (Ath) At5g01330 GI:15240952
Arabidopsis thaliana (Ath) At5g54960 GI:15240423
Saccharomyces cerevisiae (Sce) YDL080c
(S000002238)		 GI:6320123 Q07471
Saccharomyces cerevisiae (Sce) YDR380w
(S000002788)		 GI:6320588 Q06408
Saccharomyces cerevisiae (Sce) YGR087c
(S000003319)		 GI:6321524 P26263
Saccharomyces cerevisiae (Sce) YLR044c
(S000004034)		 GI:6323073 P06169
Saccharomyces cerevisiae (Sce) YLR134w
(S000004124)		 GI:6323163 P16467
Schizosaccharomyces pombe (Spo) SPAC13A11.06 GI:19113906 Q09737
Schizosaccharomyces pombe (Spo) SPAC186.09 GI:19115939 Q9P7P6
Schizosaccharomyces pombe (Spo) SPAC1F8.07c GI:19113708 Q92345
Schizosaccharomyces pombe (Spo) SPAC3G9.11c GI:19114995 O42873
Arabidopsis thaliana (Ath) At4g33070 GI:15234062
Arabidopsis thaliana (Ath) At5g01320 GI:15240950
Arabidopsis thaliana (Ath) At5g01330 GI:15240952
Arabidopsis thaliana (Ath) At5g54960 GI:15240423
Saccharomyces cerevisiae (Sce) YDL080c
(S000002238)		 GI:6320123 Q07471
Saccharomyces cerevisiae (Sce) YDR380w
(S000002788)		 GI:6320588 Q06408
Saccharomyces cerevisiae (Sce) YGR087c
(S000003319)		 GI:6321524 P26263
Saccharomyces cerevisiae (Sce) YLR044c
(S000004034)		 GI:6323073 P06169
Saccharomyces cerevisiae (Sce) YLR134w
(S000004124)		 GI:6323163 P16467
Schizosaccharomyces pombe (Spo) SPAC13A11.06 GI:19113906 Q09737
Schizosaccharomyces pombe (Spo) SPAC186.09 GI:19115939 Q9P7P6
Schizosaccharomyces pombe (Spo) SPAC1F8.07c GI:19113708 Q92345
Schizosaccharomyces pombe (Spo) SPAC3G9.11c GI:19114995 O42873


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt5g01320
At5g54960
SpoSPAC1F8.07c
GO:0005634 nucleus C
IDA
SceS000004034
S000002238
S000004124
SpoSPAC3G9.11c
SPAC13A11.06
SPAC186.09
GO:0005737 cytoplasm C
IDA
SceS000003319
S000004124
S000004034
S000002788
GO:0005829 cytosol C
IDA
SceS000002238
S000004034
SpoSPAC3G9.11c
SPAC13A11.06
SPAC186.09
GO:0016020 membrane C
IDA
AthAt4g33070
GO:0004737 pyruvate decarboxylase activity F
IDA
SceS000004034
S000004124
IGI
SceS000004124
IMP
SceS000003319
ISS
AthAt5g01330
At5g01320
At4g33070
At5g54960
SceS000002788
SpoSPAC1F8.07c
SPAC13A11.06
SPAC186.09
GO:0016831 carboxy-lyase activity F
IMP
SceS000002788
S000002238
ISS
SceS000002238
S000002788
GO:0050177 phenylpyruvate decarboxylase activity F
IDA
SceS000002788
GO:0000949 aromatic amino acid family catabolic process to
alcohol via Ehrlich pathway		 P
IGI
SceS000003319
S000002788
S000004034
S000004124
ISS
SpoSPAC13A11.06
GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway		 P
IGI
SceS000002238
S000002788
GO:0000951 methionine catabolic process to
3-methylthiopropanol		 P
IMP
SceS000002788
GO:0001666 response to hypoxia P
IEP
AthAt5g54960
GO:0006066 alcohol metabolic process P
RCA
SceS000004034
GO:0006067 ethanol metabolic process P
IMP
SceS000003319
GO:0006082 organic acid metabolic process P
RCA
SceS000004034
GO:0006090 pyruvate metabolic process P
IDA
SceS000004124
S000004034
IGI
SceS000004124
ISS
SpoSPAC1F8.07c
SPAC13A11.06
SPAC186.09
NAS
SpoSPAC3G9.11c
GO:0006091 generation of precursor metabolites and
energy		 P
NAS
SpoSPAC1F8.07c
SPAC3G9.11c
SPAC186.09
GO:0006417 regulation of translation P
RCA
SceS000004034
GO:0006552 leucine catabolic process P
IGI
SceS000002238
S000002788
IMP
SceS000002788
GO:0006559 L-phenylalanine catabolic process P
IDA
SceS000002788
IGI
SceS000002788
S000003319
S000004034
S000004124
GO:0006569 tryptophan catabolic process P
IGI
SceS000002788
S000004034
S000003319
S000004124
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000003319
GO:0008152 metabolic process P
NAS
SpoSPAC1F8.07c
GO:0009063 cellular amino acid catabolic process P
ISS
SpoSPAC186.09
SPAC3G9.11c
SPAC1F8.07c
GO:0019655 glucose catabolic process to ethanol P
IDA
SceS000004034
S000004124
IGI
SceS000004124
ISS
SpoSPAC13A11.06
GO:0044237 cellular metabolic process P
NAS
SpoSPAC1F8.07c
GO:0044238 primary metabolic process P
NAS
SpoSPAC1F8.07c
GO:0044262 cellular carbohydrate metabolic
process		 P
RCA
SceS000004034
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000002238
GO:0070623 regulation of thiamin biosynthetic
process		 P
IMP
SceS000002238
IPI
SceS000002238

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38802

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ARO10
(S000002788)		 GI:6320588 Q06408
Kluyveromyces lactis (Kla) KLLA0E02662g GI:50308135
Eremothecium gossypii (Ego) AGOS_ACR211W GI:45185897


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002788
GO:0004737 pyruvate decarboxylase activity F
ISS
SceS000002788
GO:0016831 carboxy-lyase activity F
IMP
SceS000002788
ISS
SceS000002788
GO:0050177 phenylpyruvate decarboxylase activity F
IDA
SceS000002788
GO:0000949 aromatic amino acid family catabolic process to
alcohol via Ehrlich pathway		 P
IGI
SceS000002788
GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway		 P
IGI
SceS000002788
GO:0000951 methionine catabolic process to
3-methylthiopropanol		 P
IMP
SceS000002788
GO:0006552 leucine catabolic process P
IGI
SceS000002788
IMP
SceS000002788
GO:0006559 L-phenylalanine catabolic process P
IDA
SceS000002788
IGI
SceS000002788
GO:0006569 tryptophan catabolic process P
IGI
SceS000002788

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24795

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1258 ACR211W
Candida glabrata (Cgl) cgl129 CAGL0A03102g
Debaryomyces hansenii (Dha) dha2788 DEHA0D11066g
Kluyveromyces lactis (Kla) kla3067 KLLA0E02662g
Saccharomyces cerevisiae (Sce) sce1444 YDR380W
(S000002788)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000002788
GO:0004737 pyruvate decarboxylase activity F
ISS
SceS000002788
GO:0016831 carboxy-lyase activity F
IMP
SceS000002788
ISS
SceS000002788
GO:0050177 phenylpyruvate decarboxylase activity F
IDA
SceS000002788
GO:0000949 aromatic amino acid family catabolic process to
alcohol via Ehrlich pathway		 P
IGI
SceS000002788
GO:0000950 branched chain family amino acid catabolic process
to alcohol via Ehrlich pathway		 P
IGI
SceS000002788
GO:0000951 methionine catabolic process to
3-methylthiopropanol		 P
IMP
SceS000002788
GO:0006552 leucine catabolic process P
IGI
SceS000002788
IMP
SceS000002788
GO:0006559 L-phenylalanine catabolic process P
IDA
SceS000002788
IGI
SceS000002788
GO:0006569 tryptophan catabolic process P
IGI
SceS000002788

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s.khadayate@ucl.ac.uk