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Search term: YDR381W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YRA1
SGD link S000002789
Alternative ID YDR381W
Description RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; functionally redundant with Yra2p, another REF family member
Synonyms YDR381W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0533 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RRM motif-containing protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g66260 GI:12323574
Arabidopsis thaliana (Ath) At5g02530 GI:15241854
Arabidopsis thaliana (Ath) At5g37720 GI:15240320
Arabidopsis thaliana (Ath) At5g59950 GI:15238570
Caenorhabditis elegans (Cel) CE02954
(WBGene00000120)		 GI:17538372 Q17561
Caenorhabditis elegans (Cel) CE06198
(WBGene00000122)		 GI:17541570
Caenorhabditis elegans (Cel) CE09586
(WBGene00000121)		 GI:17539984 O62183
Caenorhabditis elegans (Cel) CE16801
(WBGene00015329)		 GI:17538402 O44444
Caenorhabditis elegans (Cel) CE26061
(WBGene00021364)		 GI:17543086 Q9N442
Drosophila melanogaster (Dme) 7293508 GI:7293508
Drosophila melanogaster (Dme) 7297959 GI:7297959 Q9VK76
Drosophila melanogaster (Dme) 7298863 GI:5679350
Homo sapiens (Hsa) Hs14779319 GI:14779319
Homo sapiens (Hsa) Hs17572810 GI:17572810
Saccharomyces cerevisiae (Sce) YDR381w
(S000002789)		 GI:6320589 Q12159
Schizosaccharomyces pombe (Spo) SPBC106.12c GI:19111953 Q9URV0
Schizosaccharomyces pombe (Spo) SPBC1D7.04c GI:19112507
Arabidopsis thaliana (Ath) At1g66260 GI:12323574
Arabidopsis thaliana (Ath) At5g02530 GI:15241854
Arabidopsis thaliana (Ath) At5g37720 GI:15240320
Arabidopsis thaliana (Ath) At5g59950 GI:15238570
Caenorhabditis elegans (Cel) CE02954
(WBGene00000120)		 GI:17538372 Q17561
Caenorhabditis elegans (Cel) CE06198
(WBGene00000122)		 GI:17541570
Caenorhabditis elegans (Cel) CE09586
(WBGene00000121)		 GI:17539984 O62183
Caenorhabditis elegans (Cel) CE16801
(WBGene00015329)		 GI:17538402 O44444
Caenorhabditis elegans (Cel) CE26061
(WBGene00021364)		 GI:17543086 Q9N442
Drosophila melanogaster (Dme) 7293508 GI:7293508
Drosophila melanogaster (Dme) 7297959 GI:7297959 Q9VK76
Drosophila melanogaster (Dme) 7298863 GI:5679350
Homo sapiens (Hsa) Hs14779319 GI:14779319
Homo sapiens (Hsa) Hs17572810 GI:17572810
Saccharomyces cerevisiae (Sce) YDR381w
(S000002789)		 GI:6320589 Q12159
Schizosaccharomyces pombe (Spo) SPBC106.12c GI:19111953 Q9URV0
Schizosaccharomyces pombe (Spo) SPBC1D7.04c GI:19112507
Arabidopsis thaliana (Ath) At1g66260 GI:12323574
Arabidopsis thaliana (Ath) At5g02530 GI:15241854
Arabidopsis thaliana (Ath) At5g37720 GI:15240320
Arabidopsis thaliana (Ath) At5g59950 GI:15238570
Caenorhabditis elegans (Cel) CE02954
(WBGene00000120)		 GI:17538372 Q17561
Caenorhabditis elegans (Cel) CE06198
(WBGene00000122)		 GI:17541570
Caenorhabditis elegans (Cel) CE09586
(WBGene00000121)		 GI:17539984 O62183
Caenorhabditis elegans (Cel) CE16801
(WBGene00015329)		 GI:17538402 O44444
Caenorhabditis elegans (Cel) CE26061
(WBGene00021364)		 GI:17543086 Q9N442
Drosophila melanogaster (Dme) 7293508 GI:7293508
Drosophila melanogaster (Dme) 7297959 GI:7297959 Q9VK76
Drosophila melanogaster (Dme) 7298863 GI:5679350
Homo sapiens (Hsa) Hs14779319 GI:14779319
Homo sapiens (Hsa) Hs17572810 GI:17572810
Saccharomyces cerevisiae (Sce) YDR381w
(S000002789)		 GI:6320589 Q12159
Schizosaccharomyces pombe (Spo) SPBC106.12c GI:19111953 Q9URV0
Schizosaccharomyces pombe (Spo) SPBC1D7.04c GI:19112507


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000346 transcription export complex C
IPI
SceS000002789
GO:0000347 THO complex C
ISS
SpoSPBC106.12c
GO:0005575 cellular_component C
ND
AthAt1g66260
At5g02530
GO:0005634 nucleus C
IDA
SpoSPBC106.12c
GO:0005730 nucleolus C
IDA
AthAt5g37720
SpoSPBC106.12c
GO:0003676 nucleic acid binding F
ISS
AthAt5g59950
At5g37720
At5g02530
At1g66260
GO:0003723 RNA binding F
IDA
SceS000002789
ISS
SpoSPBC106.12c
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
ISS
SpoSPBC106.12c
GO:0006283 transcription-coupled nucleotide-excision
repair		 P
IMP
SceS000002789
GO:0006397 mRNA processing P
ISS
SpoSPBC106.12c
GO:0006406 mRNA export from nucleus P
IGI
SceS000002789
ISS
SpoSPBC106.12c
GO:0008150 biological_process P
ND
AthAt5g59950
At5g37720
At5g02530
At1g66260
GO:0034243 regulation of RNA elongation from RNA polymerase
II promoter		 P
ISS
SpoSPBC106.12c
GO:0040011 locomotion P
IMP
CelWBGene00000121
WBGene00000122
WBGene00000120

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
36237

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) mlo3
(SPBC1D7.04)		 GI:19112507 Q09330
Saccharomyces cerevisiae (Sce) YRA1
(S000002789)		 GI:6320589 Q12159
Kluyveromyces lactis (Kla) KLLA0E02706g GI:50308139
Eremothecium gossypii (Ego) AGOS_AFR149C GI:45198667
Magnaporthe grisea (Mgr) MGG_06668 GI:39977567
Neurospora crassa (Ncr) NCU01793.1 GI:32415505


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000346 transcription export complex C
IPI
SceS000002789
ISS
SpoSPBC1D7.04
GO:0005634 nucleus C
IDA
SpoSPBC1D7.04
GO:0003723 RNA binding F
IDA
SceS000002789
ISS
SpoSPBC1D7.04
GO:0005515 protein binding F
IPI
SpoSPBC1D7.04
GO:0006283 transcription-coupled nucleotide-excision
repair		 P
IMP
SceS000002789
GO:0006406 mRNA export from nucleus P
IGI
SceS000002789
GO:0016973 poly(A)+ mRNA export from nucleus P
IGI
SpoSPBC1D7.04
IMP
SpoSPBC1D7.04

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_7855

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3341 AFR149C
Caenorhabditis elegans (Cel) cel714 C01F6.5
(CE02954;
WBGene00000120)
Candida glabrata (Cgl) cgl130 CAGL0A03117
Cryptococcus neoformans (Cne) cne4410 177.m03163
Debaryomyces hansenii (Dha) dha6347 DEHA0G14520g
Homo sapiens (Hsa) hsa14622 ENSP00000345570
Kluyveromyces lactis (Kla) kla3069 KLLA0E02706g
Mus musculus (Mmu) mmu1487 ENSMUSP00000080242
(MGI:1913144)		 Q4KL64
Neurospora crassa (Ncr) ncr1745 NCU01793.2
Saccharomyces cerevisiae (Sce) sce1446 YDR381W
(S000002789)
Yarrowia lipolytica (Yli) yli722 YALI0A20856g
Yarrowia lipolytica (Yli) yli723 YALI0A20878g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000346 transcription export complex C
IPI
SceS000002789
GO:0005575 cellular_component C
ND
MmuMGI:1913144
GO:0003697 single-stranded DNA binding F
IDA
MmuMGI:1913144
GO:0003723 RNA binding F
IDA
MmuMGI:1913144
SceS000002789
GO:0006283 transcription-coupled nucleotide-excision
repair		 P
IMP
SceS000002789
GO:0006406 mRNA export from nucleus P
IGI
SceS000002789
GO:0008150 biological_process P
ND
MmuMGI:1913144
GO:0040011 locomotion P
IMP
CelWBGene00000120

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1D7.04
(Q09330)		 YDR381W
(S000002789)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000346 transcription export complex C
IPI
SceS000002789
ISS
SpoSPBC1D7.04
GO:0005634 nucleus C
IDA
SpoSPBC1D7.04
GO:0003723 RNA binding F
IDA
SceS000002789
ISS
SpoSPBC1D7.04
GO:0005515 protein binding F
IPI
SpoSPBC1D7.04
GO:0006283 transcription-coupled nucleotide-excision
repair		 P
IMP
SceS000002789
GO:0006406 mRNA export from nucleus P
IGI
SceS000002789
GO:0016973 poly(A)+ mRNA export from nucleus P
IGI
SpoSPBC1D7.04
IMP
SpoSPBC1D7.04

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