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Search term: YDR385W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name EFT2
SGD link S000002793
Alternative ID YDR385W
Description Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
Synonyms YDR385W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0469 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Elongation factor 2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g56075 GI:15222834
Caenorhabditis elegans (Cel) CE15900
(WBGene00001167)		 GI:17506493 P29691
Drosophila melanogaster (Dme) 7302127 GI:7302127
Homo sapiens (Hsa) Hs22052810 GI:22052810
Homo sapiens (Hsa) Hs4503483
(EEF2)		 GI:4503483 P13639
Saccharomyces cerevisiae (Sce) YDR385w
(S000002793)		 GI:6320593 P32324
Saccharomyces cerevisiae (Sce) YOR133w
(S000005659)		 GI:6320593 P32324
Schizosaccharomyces pombe (Spo) SPAC513.01c GI:19114887 O14460
Schizosaccharomyces pombe (Spo) SPCP31B10.07 GI:19075363 O14460
Encephalitozoon cuniculi (Ecu) ECU11g1460 GI:19074946 Q8SQT7
Arabidopsis thaliana (Ath) At1g56075 GI:15222834
Caenorhabditis elegans (Cel) CE15900
(WBGene00001167)		 GI:17506493 P29691
Drosophila melanogaster (Dme) 7302127 GI:7302127
Homo sapiens (Hsa) Hs22052810 GI:22052810
Homo sapiens (Hsa) Hs4503483
(EEF2)		 GI:4503483 P13639
Saccharomyces cerevisiae (Sce) YDR385w
(S000002793)		 GI:6320593 P32324
Saccharomyces cerevisiae (Sce) YOR133w
(S000005659)		 GI:6320593 P32324
Schizosaccharomyces pombe (Spo) SPAC513.01c GI:19114887 O14460
Schizosaccharomyces pombe (Spo) SPCP31B10.07 GI:19075363 O14460
Encephalitozoon cuniculi (Ecu) ECU11g1460 GI:19074946 Q8SQT7
Arabidopsis thaliana (Ath) At1g56075 GI:15222834
Caenorhabditis elegans (Cel) CE15900
(WBGene00001167)		 GI:17506493 P29691
Drosophila melanogaster (Dme) 7302127 GI:7302127
Homo sapiens (Hsa) Hs22052810 GI:22052810
Homo sapiens (Hsa) Hs4503483
(EEF2)		 GI:4503483 P13639
Saccharomyces cerevisiae (Sce) YDR385w
(S000002793)		 GI:6320593 P32324
Saccharomyces cerevisiae (Sce) YOR133w
(S000005659)		 GI:6320593 P32324
Schizosaccharomyces pombe (Spo) SPAC513.01c GI:19114887 O14460
Schizosaccharomyces pombe (Spo) SPCP31B10.07 GI:19075363 O14460
Encephalitozoon cuniculi (Ecu) ECU11g1460 GI:19074946 Q8SQT7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCP31B10.07
GO:0005829 cytosol C
IDA
SpoSPCP31B10.07
SPAC513.01c
GO:0005840 ribosome C
ISS
SpoSPAC513.01c
SPCP31B10.07
TAS
SceS000002793
S000005659
GO:0030529 ribonucleoprotein complex C
IDA
HsaEEF2
GO:0003746 translation elongation factor activity F
TAS
SceS000005659
S000002793
SpoSPAC513.01c
SPCP31B10.07
GO:0005515 protein binding F
IPI
HsaEEF2
GO:0005525 GTP binding F
ISS
SpoSPCP31B10.07
SPAC513.01c
GO:0000003 reproduction P
IMP
CelWBGene00001167
GO:0002119 nematode larval development P
IMP
CelWBGene00001167
GO:0006414 translational elongation P
EXP
HsaEEF2
TAS
SceS000002793
S000005659
SpoSPAC513.01c
SPCP31B10.07
GO:0006417 regulation of translation P
RCA
SceS000002793
S000005659
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001167
GO:0040007 growth P
IMP
CelWBGene00001167
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001167
GO:0045901 positive regulation of translational
elongation		 P
IMP
SceS000002793

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
100816

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EEF2 GI:4503483 P13639
Canis familiaris (Cfa) EEF2 GI:73987435
Mus musculus (Mmu) Eef2
(MGI:95288)		 GI:33859482 O89069
Rattus norvegicus (Rno) Eef2
(RGD:61979)		 GI:8393296
Gallus gallus (Gga) EEF2 GI:45382453
Schizosaccharomyces pombe (Spo) SPAPYUK71.04c GI:68000026
Schizosaccharomyces pombe (Spo) eft202
(SPCP31B10.07)		 GI:19075363 O14460
Saccharomyces cerevisiae (Sce) EFT1
(S000005659)		 GI:6324707
Saccharomyces cerevisiae (Sce) EFT2
(S000002793)		 GI:6320593 P32324
Kluyveromyces lactis (Kla) KLLA0E02926g GI:50308159
Eremothecium gossypii (Ego) AGOS_AFR142C GI:45198660
Magnaporthe grisea (Mgr) MGG_01742 GI:145613301
Neurospora crassa (Ncr) NCU07700.1 GI:32415856
Oryza sativa (Osa) Os01g0742200 GI:115439863


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCP31B10.07
GO:0005829 cytosol C
IDA
SpoSPCP31B10.07
GO:0005840 ribosome C
ISS
SpoSPCP31B10.07
TAS
SceS000002793
S000005659
GO:0030529 ribonucleoprotein complex C
IDA
HsaEEF2
ISO
MmuMGI:95288
GO:0003746 translation elongation factor activity F
TAS
SceS000005659
S000002793
SpoSPCP31B10.07
GO:0005515 protein binding F
IPI
HsaEEF2
GO:0005525 GTP binding F
ISS
SpoSPCP31B10.07
GO:0006414 translational elongation P
EXP
HsaEEF2
TAS
SceS000002793
S000005659
SpoSPCP31B10.07
GO:0006417 regulation of translation P
RCA
SceS000002793
S000005659
GO:0045901 positive regulation of translational
elongation		 P
IMP
SceS000002793

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_641

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga11598 ENSANGP00000018623
Ashbya gossypii (Ago) ago3334 AFR142C
Arabidopsis thaliana (Ath) ath4950 At1g56070.1
Caenorhabditis elegans (Cel) cel7285 F25H5.4
(CE15900;
WBGene00001167)
Candida glabrata (Cgl) cgl135 CAGL0A03234g
Cryptococcus neoformans (Cne) cne946 163.m06397
Dictyostelium discoideum (Ddi) ddi13282 DDB0191363
Dictyostelium discoideum (Ddi) ddi12990 DDB0216236
Debaryomyces hansenii (Dha) dha5984 DEHA0G06380g
Drosophila melanogaster (Dme) dme3293 CG2238-PA
(FBgn0000559)
Drosophila melanogaster (Dme) dme3295 CG2238-PB
(FBgn0000559)
Drosophila melanogaster (Dme) dme3294 CG2238-PC
(FBgn0000559)
Danio rerio (Dre) dre14559 ENSDARP00000013684
Danio rerio (Dre) dre14582 ENSDARP00000014975
Danio rerio (Dre) dre19899 ENSDARP00000015299
Danio rerio (Dre) dre14581 ENSDARP00000020169
(zgc:113191)		 Q501T8
Danio rerio (Dre) dre8545 ENSDARP00000024752
(eef2l)		 Q6P3J5
Danio rerio (Dre) dre14583 ENSDARP00000031681
(LOC568904)		 Q1LYG6
Danio rerio (Dre) dre14580 ENSDARP00000044304
Encephalitozoon cuniculi (Ecu) ecu1034 19074946
Takifugu rubripes (Fru) fru29958 SINFRUP00000175273
Gallus gallus (Gga) gga14107 ENSGALP00000002828
(EEF2)		 Q90705
Homo sapiens (Hsa) hsa15346 ENSP00000307940
(EEF2)		 P13639
Kluyveromyces lactis (Kla) kla3079 KLLA0E02926g
Mus musculus (Mmu) mmu2563 ENSMUSP00000046101
(MGI:95288)		 P58252
Neurospora crassa (Ncr) ncr7497 NCU07700.2
Oryza sativa (Osa) osa4889 2341.m00124
Oryza sativa (Osa) osa11948 2808.m00177
Oryza sativa (Osa) osa31786 4392.m00141
Oryza sativa (Osa) osa32897 4621.m00159
Oryza sativa (Osa) osa58091 6251.m00118
Oryza sativa (Osa) osa81300 8215.m00164
Plasmodium falciparum (Pfa) pfa1166 PF14_0486
Rattus norvegicus (Rno) rno26204 ENSRNOP00000027598
Rattus norvegicus (Rno) rno26205 ENSRNOP00000041821
(RGD:61979)		 P05197
Saccharomyces cerevisiae (Sce) sce1450 YDR385W
(S000002793)
Saccharomyces cerevisiae (Sce) sce5870 YOR133W
(S000005659)
Schizosaccharomyces pombe (Spo) spo2384 SPAC513.01c O14460
Schizosaccharomyces pombe (Spo) spo4788 SPCP31B10.07 O14460
Yarrowia lipolytica (Yli) yli10 YALI0A00352g
Yarrowia lipolytica (Yli) yli690 YALI0A20152g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0486
GO:0005730 nucleolus C
IDA
AthAt1g56070
GO:0005737 cytoplasm C
IDA
SpoSPCP31B10.07
NAS
DmeFBgn0000559
GO:0005811 lipid particle C
IDA
DmeFBgn0000559
GO:0005829 cytosol C
IDA
AthAt1g56070
SpoSPCP31B10.07
SPAC513.01c
ISS
DmeFBgn0000559
GO:0005840 ribosome C
ISS
SpoSPAC513.01c
SPCP31B10.07
TAS
SceS000002793
S000005659
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0000559
GO:0005886 plasma membrane C
IDA
AthAt1g56070
GO:0009507 chloroplast C
IDA
AthAt1g56070
GO:0016020 membrane C
IDA
AthAt1g56070
GO:0030529 ribonucleoprotein complex C
ISO
MmuMGI:95288
GO:0003746 translation elongation factor activity F
ISS
AthAt1g56070
DmeFBgn0000559
PfaPF14_0486
NAS
DmeFBgn0000559
TAS
SceS000005659
S000002793
SpoSPAC513.01c
SPCP31B10.07
GO:0005507 copper ion binding F
IDA
AthAt1g56070
GO:0005525 GTP binding F
ISS
SpoSPCP31B10.07
SPAC513.01c
GO:0008135 translation factor activity, nucleic acid
binding		 F
ISS
AthAt1g56070
GO:0000003 reproduction P
IMP
CelWBGene00001167
GO:0000022 mitotic spindle elongation P
IMP
DmeFBgn0000559
GO:0002119 nematode larval development P
IMP
CelWBGene00001167
GO:0006412 translation P
NAS
DmeFBgn0000559
GO:0006414 translational elongation P
ISS
DmeFBgn0000559
PfaPF14_0486
TAS
SceS000002793
S000005659
SpoSPAC513.01c
SPCP31B10.07
GO:0006417 regulation of translation P
RCA
SceS000002793
S000005659
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0000559
GO:0009409 response to cold P
IMP
AthAt1g56070
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001167
GO:0040007 growth P
IMP
CelWBGene00001167
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001167
GO:0045901 positive regulation of translational
elongation		 P
IMP
SceS000002793

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCP31B10.07
(O14460)		 YDR385W
(S000002793)
SPAC513.01c
(O14460)		 YDR385W
(S000002793)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCP31B10.07
GO:0005829 cytosol C
IDA
SpoSPCP31B10.07
SPAC513.01c
GO:0005840 ribosome C
ISS
SpoSPAC513.01c
SPCP31B10.07
TAS
SceS000002793
GO:0003746 translation elongation factor activity F
TAS
SceS000002793
SpoSPAC513.01c
SPCP31B10.07
GO:0005525 GTP binding F
ISS
SpoSPCP31B10.07
SPAC513.01c
GO:0006414 translational elongation P
TAS
SceS000002793
SpoSPAC513.01c
SPCP31B10.07
GO:0006417 regulation of translation P
RCA
SceS000002793
GO:0045901 positive regulation of translational
elongation		 P
IMP
SceS000002793

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