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Search term: YDR397C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NCB2
SGD link S000002805
Alternative ID YDR397C
Description Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta
Synonyms YDR397C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0871 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Class 2 transcription repressor NC2, beta subunit (Dr1)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g08190 GI:11279032
Arabidopsis thaliana (Ath) At5g23090 GI:15237218
Caenorhabditis elegans (Cel) CE16097
(WBGene00001092)		 GI:17552846 O45550
Drosophila melanogaster (Dme) 7298194
(NC2beta)		 GI:19921362
Homo sapiens (Hsa) Hs4503381
(DR1)		 GI:4503381 Q01658
Saccharomyces cerevisiae (Sce) YDR397c
(S000002805)		 GI:6320605 Q92317
Schizosaccharomyces pombe (Spo) SPBC30D10.02 GI:19113075 O14348
Encephalitozoon cuniculi (Ecu) ECU11g0730 GI:19074873 Q8SQX5
Arabidopsis thaliana (Ath) At5g08190 GI:11279032
Arabidopsis thaliana (Ath) At5g23090 GI:15237218
Caenorhabditis elegans (Cel) CE16097
(WBGene00001092)		 GI:17552846 O45550
Drosophila melanogaster (Dme) 7298194
(NC2beta)		 GI:19921362
Homo sapiens (Hsa) Hs4503381
(DR1)		 GI:4503381 Q01658
Saccharomyces cerevisiae (Sce) YDR397c
(S000002805)		 GI:6320605 Q92317
Schizosaccharomyces pombe (Spo) SPBC30D10.02 GI:19113075 O14348
Encephalitozoon cuniculi (Ecu) ECU11g0730 GI:19074873 Q8SQX5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
NAS
SpoSPBC30D10.02
GO:0005634 nucleus C
IDA
AthAt5g23090
DmeNC2beta
SpoSPBC30D10.02
IPI
SceS000002805
ISS
SpoSPBC30D10.02
GO:0005829 cytosol C
IDA
SpoSPBC30D10.02
GO:0017054 negative cofactor 2 complex C
IDA
SceS000002805
NAS
DmeNC2beta
GO:0003677 DNA binding F
ISS
AthAt5g08190
TAS
HsaDR1
GO:0003700 transcription factor activity F
ISS
AthAt5g08190
At5g23090
GO:0003702 RNA polymerase II transcription factor
activity		 F
IDA
DmeNC2beta
GO:0003713 transcription coactivator activity F
IDA
SceS000002805
GO:0003714 transcription corepressor activity F
IGI
SceS000002805
IMP
SceS000002805
ISS
SpoSPBC30D10.02
TAS
HsaDR1
GO:0005515 protein binding F
IPI
DmeNC2beta
GO:0008134 transcription factor binding F
TAS
HsaDR1
GO:0016563 transcription activator activity F
IDA
DmeNC2beta
GO:0016564 transcription repressor activity F
IDA
DmeNC2beta
GO:0016565 general transcriptional repressor
activity		 F
NAS
DmeNC2beta
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeNC2beta
IGI
SceS000002805
IMP
SceS000002805
NAS
SpoSPBC30D10.02
TAS
HsaDR1
GO:0017055 negative regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
NAS
DmeNC2beta
GO:0045449 regulation of transcription P
TAS
AthAt5g08190
At5g23090
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeNC2beta
SceS000002805

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
38809

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DR1 GI:4503381 Q01658
Pan troglodytes (Ptr) DR1 GI:114557737
Canis familiaris (Cfa) DR1 GI:57088223
Mus musculus (Mmu) Dr1
(MGI:1100515)		 GI:27754097 Q3UMQ2
Rattus norvegicus (Rno) Dr1
(RGD:1305201)		 GI:58865406
Gallus gallus (Gga) DR1 GI:56605968
Drosophila melanogaster (Dme) NC2beta GI:19921362
Anopheles gambiae (Aga) AgaP_AGAP010322 GI:58391043
Caenorhabditis elegans (Cel) dro-1
(CE16097;
WBGene00001092)		 GI:17552846 O45550
Schizosaccharomyces pombe (Spo) SPBC30D10.02 GI:19113075 O14348
Saccharomyces cerevisiae (Sce) NCB2
(S000002805)		 GI:6320605 Q92317
Kluyveromyces lactis (Kla) KLLA0C06611g GI:50305067
Eremothecium gossypii (Ego) AGOS_AFR397C GI:45198915
Magnaporthe grisea (Mgr) MGG_02824 GI:39970715
Neurospora crassa (Ncr) NCU02017.1 GI:32417458
Arabidopsis thaliana (Ath) NF-YB12 GI:18415737
Arabidopsis thaliana (Ath) NF-YB13 GI:30688813
Oryza sativa (Osa) Os08g0383700 GI:115476204


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
NAS
SpoSPBC30D10.02
GO:0005634 nucleus C
IDA
AthNF-YB13
DmeNC2beta
MmuMGI:1100515
SpoSPBC30D10.02
IPI
SceS000002805
ISS
SpoSPBC30D10.02
GO:0005829 cytosol C
IDA
SpoSPBC30D10.02
GO:0017054 negative cofactor 2 complex C
IDA
SceS000002805
NAS
DmeNC2beta
GO:0003677 DNA binding F
ISS
AthNF-YB12
TAS
HsaDR1
GO:0003700 transcription factor activity F
ISS
AthNF-YB13
NF-YB12
GO:0003702 RNA polymerase II transcription factor
activity		 F
IDA
DmeNC2beta
GO:0003713 transcription coactivator activity F
IDA
SceS000002805
GO:0003714 transcription corepressor activity F
IGI
SceS000002805
IMP
SceS000002805
ISS
SpoSPBC30D10.02
TAS
HsaDR1
GO:0005515 protein binding F
IPI
DmeNC2beta
MmuMGI:1100515
GO:0008134 transcription factor binding F
TAS
HsaDR1
GO:0016563 transcription activator activity F
IDA
DmeNC2beta
GO:0016564 transcription repressor activity F
IDA
DmeNC2beta
GO:0016565 general transcriptional repressor
activity		 F
NAS
DmeNC2beta
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeNC2beta
IGI
SceS000002805
IMP
SceS000002805
NAS
SpoSPBC30D10.02
TAS
HsaDR1
GO:0008150 biological_process P
ND
MmuMGI:1100515
GO:0017055 negative regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
NAS
DmeNC2beta
GO:0045449 regulation of transcription P
TAS
AthNF-YB13
NF-YB12
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeNC2beta
SceS000002805

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3294

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga13970 ENSANGP00000017122
Ashbya gossypii (Ago) ago3589 AFR397C
Arabidopsis thaliana (Ath) ath23036 At5g08190.1
Arabidopsis thaliana (Ath) ath24550 At5g23090.1
Arabidopsis thaliana (Ath) ath24551 At5g23090.2
Arabidopsis thaliana (Ath) ath24552 At5g23090.3
Caenorhabditis elegans (Cel) cel9936 F53A2.5
(CE16097;
WBGene00001092)
Candida glabrata (Cgl) cgl4719 CAGL0M01474g
Cryptococcus neoformans (Cne) cne881 163.m06259
Dictyostelium discoideum (Ddi) ddi11470 DDB0216393
Debaryomyces hansenii (Dha) dha5904 DEHA0G04675g
Drosophila melanogaster (Dme) dme2462 CG4185-PA
(FBgn0028926)
Encephalitozoon cuniculi (Ecu) ecu961 19074873
Takifugu rubripes (Fru) fru25319 SINFRUP00000136643
Gallus gallus (Gga) gga22484 ENSGALP00000009403
(DR1)		 Q5ZMV3
Homo sapiens (Hsa) hsa1511 ENSP00000236164
Kluyveromyces lactis (Kla) kla1491 KLLA0C06611g
Mus musculus (Mmu) mmu20565 ENSMUSP00000031190
(MGI:1100515)		 Q91WV0
Neurospora crassa (Ncr) ncr1961 NCU02017.2
Oryza sativa (Osa) osa40160 5010.m00039
Oryza sativa (Osa) osa80539 8162.m00178
Rattus norvegicus (Rno) rno9898 ENSRNOP00000000080
(RGD:1305201)		 Q5XI68
Saccharomyces cerevisiae (Sce) sce1462 YDR397C
(S000002805)
Schizosaccharomyces pombe (Spo) spo788 SPBC30D10.02 O14348
Yarrowia lipolytica (Yli) yli4531 YALI0E16294g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
NAS
SpoSPBC30D10.02
GO:0005634 nucleus C
IDA
AthAt5g23090
DmeFBgn0028926
MmuMGI:1100515
SpoSPBC30D10.02
IPI
SceS000002805
ISS
SpoSPBC30D10.02
GO:0005829 cytosol C
IDA
SpoSPBC30D10.02
GO:0017054 negative cofactor 2 complex C
IDA
SceS000002805
NAS
DmeFBgn0028926
GO:0003677 DNA binding F
ISS
AthAt5g08190
GO:0003700 transcription factor activity F
ISS
AthAt5g08190
At5g23090
GO:0003702 RNA polymerase II transcription factor
activity		 F
IDA
DmeFBgn0028926
GO:0003713 transcription coactivator activity F
IDA
SceS000002805
GO:0003714 transcription corepressor activity F
IGI
SceS000002805
IMP
SceS000002805
ISS
SpoSPBC30D10.02
GO:0005515 protein binding F
IPI
DmeFBgn0028926
MmuMGI:1100515
GO:0016563 transcription activator activity F
IDA
DmeFBgn0028926
GO:0016564 transcription repressor activity F
IDA
DmeFBgn0028926
GO:0016565 general transcriptional repressor
activity		 F
NAS
DmeFBgn0028926
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeFBgn0028926
IGI
SceS000002805
IMP
SceS000002805
NAS
SpoSPBC30D10.02
GO:0008150 biological_process P
ND
MmuMGI:1100515
GO:0017055 negative regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
NAS
DmeFBgn0028926
GO:0045449 regulation of transcription P
TAS
AthAt5g08190
At5g23090
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IDA
DmeFBgn0028926
SceS000002805

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30D10.02
(O14348)		 YDR397C
(S000002805)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
NAS
SpoSPBC30D10.02
GO:0005634 nucleus C
IDA
SpoSPBC30D10.02
IPI
SceS000002805
ISS
SpoSPBC30D10.02
GO:0005829 cytosol C
IDA
SpoSPBC30D10.02
GO:0017054 negative cofactor 2 complex C
IDA
SceS000002805
GO:0003713 transcription coactivator activity F
IDA
SceS000002805
GO:0003714 transcription corepressor activity F
IGI
SceS000002805
IMP
SceS000002805
ISS
SpoSPBC30D10.02
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IGI
SceS000002805
IMP
SceS000002805
NAS
SpoSPBC30D10.02
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000002805

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GO info in one table:

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