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Search term: YDR399W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HPT1
SGD link S000002807
Alternative ID YDR399W
Description Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
Synonyms YDR399W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48650

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HPT1
(S000002807)		 GI:6320607
Kluyveromyces lactis (Kla) KLLA0C06655g GI:50305071


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002807
GO:0005737 cytoplasm C
IDA
SceS000002807
GO:0004422 hypoxanthine phosphoribosyltransferase
activity		 F
IDA
SceS000002807
IGI
SceS000002807
IMP
SceS000002807
GO:0032263 GMP salvage P
IDA
SceS000002807
GO:0032264 IMP salvage P
IDA
SceS000002807
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002807

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_9328

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago522 ABL070C
Candida glabrata (Cgl) cgl1339 CAGL0F02563g
Candida glabrata (Cgl) cgl4676 CAGL0M00484g
Cryptococcus neoformans (Cne) cne2898 167.m03172
Debaryomyces hansenii (Dha) dha5899 DEHA0G04565g
Kluyveromyces lactis (Kla) kla716 KLLA0B04158g
Kluyveromyces lactis (Kla) kla1493 KLLA0C06655g
Neurospora crassa (Ncr) ncr5384 NCU05542.2
Saccharomyces cerevisiae (Sce) sce1464 YDR399W
(S000002807)
Saccharomyces cerevisiae (Sce) sce3629 YJR133W
(S000003894)
Schizosaccharomyces pombe (Spo) spo4810 SPAC23C11.13c O13917
Yarrowia lipolytica (Yli) yli4552 YALI0E16753g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002807
ISS
SpoSPAC23C11.13c
GO:0005737 cytoplasm C
IDA
SceS000002807
S000003894
ISS
SpoSPAC23C11.13c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C11.13c
GO:0000310 xanthine phosphoribosyltransferase
activity		 F
IMP
SceS000003894
GO:0004422 hypoxanthine phosphoribosyltransferase
activity		 F
IDA
SceS000002807
IGI
SceS000003894
S000002807
IMP
SceS000002807
ISS
SpoSPAC23C11.13c
GO:0032261 purine nucleotide salvage P
ISS
SpoSPAC23C11.13c
GO:0032263 GMP salvage P
IDA
SceS000002807
GO:0032264 IMP salvage P
IDA
SceS000002807
GO:0032265 XMP salvage P
IMP
SceS000003894
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002807
GO:0046100 hypoxanthine metabolic process P
IGI
SceS000003894

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C11.13c
(O13917)		 YDR399W
(S000002807)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000002807
ISS
SpoSPAC23C11.13c
GO:0005737 cytoplasm C
IDA
SceS000002807
ISS
SpoSPAC23C11.13c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC23C11.13c
GO:0004422 hypoxanthine phosphoribosyltransferase
activity		 F
IDA
SceS000002807
IGI
SceS000002807
IMP
SceS000002807
ISS
SpoSPAC23C11.13c
GO:0032261 purine nucleotide salvage P
ISS
SpoSPAC23C11.13c
GO:0032263 GMP salvage P
IDA
SceS000002807
GO:0032264 IMP salvage P
IDA
SceS000002807
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000002807

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